Search clinical trials for: Healthy volunteers, pharmacokinetic, inhalation

Total 30222 results

Guangdong Hengrui Pharmaceutical Co., Ltd

Not yet recruiting

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of SHR-4597 Inhalation in Healthy Subjects and Asthmatic Patients

Healthy Subjects | Asthmatic Patients
University Hospital, Rouen

Not yet recruiting

Nebulized Fentanyl in Healthy Volunteers (AEROfen)

Emergencies | Analgesia

France
Respirent Pharmaceuticals Co Ltd.
Becro Ltd.

Recruiting

Bioequivalence Study for Fluticasone Propionate 500 mcg/Salmeterol Xinafoate 50 mcg Inhalation Powder in Healthy Volunteers

Bioequivalence

Greece
CanSino Biologics Inc.

Recruiting

A Study to Evaluate the Safety and Immunogenicity of ChAdOx1-VZV in Healthy Adults Aged 50-65 Years

Herpes Zoster

Canada
Pharmosa Biopharm Inc.
Novotech (Australia) Pty Limited

Recruiting

Safety, Tolerability and Pharmacokinetics of L608 in Healthy Adults

Pulmonary Arterial Hypertension

Australia
Cystetic Medicines, Inc.
DevPro Biopharma

Recruiting

Study to Assess Amphotericin B Cystetic for Inhalation (ABCI) Doses in Healthy Volunteers & People With Cystic Fibrosis (ABCI)

Cystic Fibrosis

Australia, New Zealand
University of Kansas Medical Center
Johns Hopkins University; M.D. Anderson Cancer Center; Baylor College of Medicine and other collaborators

Not yet recruiting

Hyperpolarized 129Xe MRI Lung Health Cohort (XeLHC)

Healthy

United States
Guangdong Hengrui Pharmaceutical Co., Ltd

Recruiting

Study on Single and Multiple Atomization Inhalation of HRS-9821 Suspension for Inhalation in Healthy Subjects

Chronic Obstructive Pulmonary Disease

China
Arrowhead Pharmaceuticals

Recruiting

Study of ARO-MMP7 Inhalation Solution in Healthy Subjects and Patients With Idiopathic Pulmonary Fibrosis

Idiopathic Pulmonary Fibrosis

Denmark, New Zealand, Spain
Respirent Pharmaceuticals Co Ltd.
Becro Ltd.

Recruiting

A Bioequivalence Study Between Fluticasone Propionate 100 mcg/Blister Oral Inhalation Powder/Respirent Pharmaceuticals vs. FLOVENT DISKUS® 100 mcg/Blister Oral Inhalation Powder /GSK in Healthy Volunteers Under Fasting Conditions

Asthma | Bioequivalence

Greece
The Hospital for Sick Children

Recruiting

Development of Hardware and Software for Pulmonary Magnetic Resonance Imaging Using Inhaled Tracer Gases

Healthy Volunteers

Canada
University of Saskatchewan

Recruiting

Effect of Multimodal Opioid-free Anesthesia on Return of Bowel Function in Laparoscopic Colorectal Surgery (RUMBLE)

Laparoscopic Surgery | Analgesia | Colorectal Surgery | Anesthesia | Ketamine | General Anesthesia | Dexmedetomidine | Postoperative Ileus | Analgesics, Opioid | Lidocaine | Opioid Free Anesthesia

Canada
The Hospital for Sick Children

Recruiting

Xenon-129 Lung Magnetic Resonance Imaging: Study of Healthy Volunteers and Participants With Pulmonary Disease

Asthma | Cystic Fibrosis

Canada
Thunder Bay Regional Health Research Institute
Lakehead University; Thunder Bay Regional Health Sciences Centre

Recruiting

HP Xenon-129 fMRI of Healthy Volunteers and Participants With Alzheimer's Disease

Alzheimer Disease

Canada
Western University, Canada
London Health Sciences Centre

Recruiting

Xenon-129 Magnetic Resonance Imaging of Healthy Subjects: Hardware and Software Development and Reproducibility

Healthy Volunteers

Canada
University of North Carolina, Chapel Hill
North Carolina Translational and Clinical Sciences Institute

Recruiting

Hyperpolarized Xenon-129 Magnetic Resonance Imaging and Spectroscopy of Brown Fat: Healthy Adult Volunteer Pilot Study

Obesity

United States
Kexing Biopharm Co., Ltd.
The Third Hospital of Changsha; Guoxin Pharmaceutical Technology (Beijing)... and other collaborators

Completed

A Phase I Study in Healthy Participants

Healthy Participants

China
Imperial College London
Duska Scientific Co.

Completed

ATP/AMP Challenge in Healthy Non-smokers, Smokers, Patients With Asthma, and Patients With Chronic Obstructive Pulmonary Disease (COPD)

Smoking | Asthma | COPD

United Kingdom
Imperial College London

Withdrawn

Endotoxin and Inflammatory Markers in Healthy Non-Smokers and Current Smokers Including Patients With Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease

United Kingdom
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Active, not recruiting

A Trial to Assess the Bioequivalence of Generic Tiotropium Bromide Inhalation Powder and Reference Product in Healthy Adult Participants Under Fasting Conditions (Pilot)

Chronic Obstructive Pulmonary Disease

China
Vectura, Inc.
Syneos Health

Completed

Study to Compare the Pharmacodynamics and Pharmacokinetics of Acetylsalicylic Acid Powder for Oral Inhalation With Non-enteric-coated Chewable Aspirin in Healthy Adults.

Healthy Volunteers

United States
Intech Biopharm Ltd.

Completed

Bioequivalence Between Albuterol Sulfate Inhalation Aerosol 108mcg Per Actuation and Proair HFA (Albuterol Sulfate) Inhalation Aerosol 90mcg Per Actuation in Healthy Volunteers Under Fasting Conditions

Healthy

Taiwan
Intech Biopharm Ltd.

Completed

Bioequivalence Between Albuterol Sulfate Inhalation Aerosol 108 mcg Per Actuation and Proair HFA (Albuterol Sulfate) Inhalation Aerosol 90 mcg Per Actuation in Healthy Volunteers Under Fasting Conditions

Healthy

Taiwan
GlaxoSmithKline

Completed

Safety, Tolerability and Pharmacokinetics of GSK3923868 Inhalation Powder in Healthy Participants and Stable Asthmatics

Pulmonary Disease, Chronic Obstructive

United Kingdom
Insmed Incorporated

Completed

A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of C16TR for Inhalation With Tyvaso® Cohort in Healthy Participants

Healthy Volunteers

United States
Pieris Australia Pty Ltd

Completed

Study of Single and Multiple Doses of PRS-220 Administered by Oral Inhalation in Healthy Subjects

Healthy

Australia
Insmed Incorporated

Completed

A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Treprostinil Palmitil Inhalation Powder (TPIP) in Healthy Participants

Healthy Volunteers

United States
Respirent Pharmaceuticals Co Ltd.
Becro Ltd.

Active, not recruiting

Bioequivalence Study for Fluticasone Propionate 250 mcg/Salmeterol Xinafoate 50 mcg Inhalation Powder in Healthy Volunteers

Bioequivalence

Greece
University of California, San Francisco
Tobacco Related Disease Research Program

Suspended

Controlled Exposure of Healthy Nonsmokers to Secondhand and Thirdhand Cigarette Smoke (THS04)

Pollution; Exposure | Exposure to Pollution | Smoke Inhalation

United States
Insmed Incorporated

Completed

A Study to Investigate Lung Deposition of Inhaled Amikacin-loaded Liposomes in Healthy Male Participants

Healthy Volunteers
Imperial Brands PLC
Nerudia Ltd

Completed

An Exploratory PET-study of Deposition, Disposition and Brain Uptake of [11C]Nicotine After Inhalation of 2 Nicotine Formulations Via the myBluTM E-cigarette in Smokers

Healthy Volunteers

Sweden
AstraZeneca
Parexel

Completed

A Study to Assess the Total Systemic Exposure Bioequivalence of of Budesonide, Glycopyrronium, and Formoterol Delivered by BGF MDI HFO Compared With BGF MDI HFA

Chronic Obstructive Pulmonary Disease

United States
AstraZeneca
Parexel

Completed

Study to Assess the Lung Exposure Bioequivalence of Budesonide, Glycopyrronium, and Formoterol Delivered by BGF MDI HFO Compared With BGF MDI HFA

Chronic Obstructive Pulmonary Disease

United States
Medtronic - MITG

Completed

Evaluation of Bispectral Index (BIS™) and Levels of Sedation With Common Inhalational Anesthetics in Healthy Volunteers (OLIVER) (OLIVER)

Anesthesia

United States
Seoul National University Hospital

Active, not recruiting

Anesthesia and Cancer Study: Renal Cell Carcinoma

Renal Cell Carcinoma

Korea, Republic of
AstraZeneca

Completed

A Clinical Trial in Healthy Volunteers and Patients With Mild Asthma to Investigate a New Medicine (AZD4604) for the Treatment of Asthma

Asthma

United Kingdom
Respirent Pharmaceuticals Co Ltd.
Becro Ltd.

Active, not recruiting

Bioequivalence Study for Fluticasone Propionate 100 mcg/Salmeterol Xinafoate 50 mcg Inhalation Powder in Healthy Volunteers

Bioequivalence

Greece
Hangzhou Sciwind Biosciences Co., Ltd.

Completed

Phase Ia Study of XW001 in Healthy Adult Subjects

Respiratory Syncytial Virus Infections

China
Frontier Biotechnologies Inc.

Completed

A Study of FB2001 for Inhalation in Healthy Chinese Adults

COVID-19 Pandemic

China
Aerami Therapeutics

Completed

Safety, Tolerability, & Pharmacokinetics Study of Single & Multiple Inhaled Doses of Imatinib Inhalation Solution

Pulmonary Arterial Hypertension

Australia
Aquilon Pharmaceuticals S.A.

Completed

Single-dose AQ001S PK Study in Healthy Volunteers (BORA)

Pharmacokinetics

Bulgaria
Respira Therapeutics, Inc.

Completed

A Healthy Volunteer Study Evaluating the the Safety, Tolerability, and Pharmacokinetics of RT234

Healthy Volunteer

Australia
NeuroSense Therapeutics Ltd.

Completed

A Pilot Study to Evaluate the PK Profile of PrimeC-ER Tablets in Healthy Adult Subjects

Pharmacokinetics

United States
Sheffield Teaching Hospitals NHS Foundation Trust

Completed

Assessment of New Magnetic Resonance Imaging (MRI) Pulse Sequences for Imaging Hyperpolarised Xenon in Lung, Heart and Brain in Volunteers

Healthy Volunteers

United Kingdom
Orion Corporation, Orion Pharma

Completed

Comparison of Tiotropium Absorption From Tiotropium Easyhaler and Spiriva HandiHaler (TEMPO)

Healthy Volunteers

Finland
Orion Corporation, Orion Pharma

Completed

Study to Compare Relative Bioavailability of 3 Indacaterol/Glycopyrronium Test Products and Reference Product (FORELLI)

Healthy Volunteers

Finland
TAK-Circulator Co.

Completed

The Safety and Pharmacokinetics Study of TAKC-02 Inhalation Solution in Healthy Adult Males.

Healthy Volunteer

Japan
Respirent Pharmaceuticals Co Ltd.
Becro Ltd.

Active, not recruiting

A Bioequivalence Study Between Fluticasone Propionate 250 mcg/Blister Oral Inhalation Powder/Respirent Pharmaceuticals vs. FLOVENT DISKUS® 250 mcg/Blister Oral Inhalation Powder /GSK in Healthy Volunteers Under Fasting Conditions

Asthma | Bioequivalence

Greece
Takeda

Completed

A Study of Danavorexton in Anesthetized Adults

Healthy Volunteers

United States
SoftOx Solutions AS

Completed

Safety of Ascending Single and Multiple Doses of Nebulised SoftOx Inhalation Solution in Healthy Subjects

Healthy Volunteers | Safety

Denmark

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