Search clinical trials for: Healthy Unrelated Stem Cell Donors

Total 85128 results

National Cancer Institute (NCI)

Recruiting

Study of Palifermin (Kepivance) in Persons Undergoing Unrelated Donor Allogeneic Hematopoietic Cell Transplantation

Multiple Myeloma | Hodgkin's Lymphoma | Non-Hodgkin's Lymphoma | Acute Leukemia | Myelodysplastic Syndrome

United States
Center for International Blood and Marrow Transplant...
National Marrow Donor Program

Recruiting

Filgrastim-Mobilized Stem Cells for Transplantation Using Unrelated Donors

Healthy

United States
National Cancer Institute (NCI)

Completed

A Phase I Study of NK Cell Infusion Following Allogeneic Peripheral Blood Stem Cell Transplantation From Related or Matched Unrelated Donors in Pediatric Patients With Solid Tumors and Leukemias

Lymphoma | Leukemia

United States
University of California, San Francisco

Completed

Filgrastim-Mobilized Peripheral Blood Stem Cells for Allogeneic Transplantation With Unrelated Donors

Healthy

United States
Center for International Blood and Marrow Transplant...
National Marrow Donor Program

Recruiting

HLA-Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation With Reduced Dose Post Transplantation Cyclophosphamide GvHD Prophylaxis (OPTIMIZE)

Lymphoma | Acute Myeloid Leukemia | Myelodysplastic Syndromes | Myelofibrosis | Chronic Myelomonocytic Leukemia | Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | Chronic Myeloid Leukemia | Acute Leukemia | Myeloproliferative Neoplasm | Pro-Lymphocytic Leukemia

United States
Children's Oncology Group

Recruiting

Mismatched Related Donor Versus Matched Unrelated Donor Stem Cell Transplantation for Children, Adolescents, and Young Adults With Acute Leukemia or Myelodysplastic Syndrome

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Myelodysplastic Syndrome | Mixed Phenotype Acute Leukemia

United States, Australia, Canada
Center for International Blood and Marrow Transplant...
National Marrow Donor Program

Recruiting

HLA-Mismatched Unrelated Donor Hematopoietic Cell Transplantation With Post-Transplantation Cyclophosphamide (ACCESS)

Lymphoma | Myelodysplastic Syndromes | Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | Acute Leukemia | Acute Myelogenous Leukemia | Chronic Myelogenous Leukemia | Mixed Phenotype Acute Leukemia

United States
University of Wisconsin, Madison
University of Wisconsin Carbone Cancer Center (UWCCC)

Not yet recruiting

Alpha/Beta T-cell Depleted Blood-forming Stem Cell Transplant From Related or Unrelated Donors for Blood Diseases in Children and Young Adults

Blood Disease
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI)

Recruiting

Reduced Intensity, Partially HLA Mismatched BMT to Treat Hematologic Malignancies

Hematologic Malignancies

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute...

Active, not recruiting

Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts From HLA-Matched Related and Unrelated Donors in Preventing GVHD

Lymphoblastic Lymphoma | Childhood Acute Myeloid Leukemia in Remission | Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | Myelodysplastic Syndrome With Excess Blasts | Childhood Acute Lymphoblastic Leukemia in Remission | Recurrent Childhood Acute Lymphoblastic Leukemia | Recurrent... and other conditions

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

AlloHCT From Matched Unrelated Donors in Pts w/ Advanced Hematologic Malignancies & Disorders

Lymphoma | Myelodysplastic Syndromes | Leukemia

United States
Dipnarine Maharaj

Enrolling by invitation

Safety, Efficacy of FFP From Healthy Donors to AmeliorateFrailty and Enhance Immune Function in Older Individuals

Frailty

United States
Dipnarine Maharaj

Enrolling by invitation

A Study Using White Blood Cells From Healthy Donors To Treat Solid Cancers

Solid Tumors

United States
Baptist Health South Florida

Withdrawn

Transplantation of Hematopoietic Stem Cells From HLA-compatible Donors in Patients With B-Cell Lymphoid Malignancies

Non-Hodgkin Lymphoma | Hematologic Malignancy | B-Cell Lymphoid Malignancies

United States
Milton S. Hershey Medical Center

Terminated

Clofarabine Pre-conditioning Followed by Stem Cell Transplant for Non-remission AML

Acute Myeloid Leukemia

United States
OHSU Knight Cancer Institute
Oregon Health and Science University

Available

Bone Marrow Transplantation Using CD34-Selected Stem Cells From Related or Unrelated Donors in Treating Participants With Cancer or Other Disorders

Malignant Neoplasm | Hematopoietic Cell Transplantation Recipient | Benign Neoplasm | Bone Marrow Transplantation Recipient

United States
Karolinska Institutet
Medical University of Vienna; Oslo University Hospital; Sahlgrenska University... and other collaborators

Terminated

Randomized Clinical Study Assessing Haplo vs. URD in AML

Acute Myeloid Leukemia

Canada, Austria, Sweden, Russian Federation, Norway
Gruppo Italiano Trapianto di Midollo Osseo

Completed

Post Transplant High-Dose Cy as GvHD Prophylaxis in 1 HLA Mismatched Unrelated HSCT for Myeloid Malignancies (GITMO-PHYLOS)

Myeloid Malignancies

Italy
Sidney Kimmel Cancer Center at Thomas Jefferson...

Completed

A Research Study of Bone Marrow Transplantation From Unrelated or Partially Matched Related Donors

Hematological Malignancies

United States
Memorial Sloan Kettering Cancer Center

Completed

HLA-Compatible Related or Unrelated Donors With CD34+ Enriched, T-cell Depleted Peripheral Blood Stem Cells Isolated by the CliniMACS System in the Treatment of Patients With Hematologic Malignancies

Multiple Myeloma | Acute Lymphoblastic Leukemia | Myelodysplastic Syndrome | Acute Myelogenous Leukemia

United States
Memorial Sloan Kettering Cancer Center

Completed

Busulfan, Melphalan, and Fludarabine With Peri-transplant Palifermin, Followed by a T-Cell Depleted Hematopoietic Stem Cell Transplant From HLA Matched or Mismatched Related or Unrelated Donors in Patients With Advanced Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML)

Acute Myeloid Leukemia | Advanced Myelodysplastic Syndromes

United States
Christopher Dvorak

No longer available

Expanded Access Protocol (EAP) Using the CliniMACS® Device for Pediatric Haplocompatible Donor Stem Cell Transplant

Acute Myeloid Leukemia | Leukocyte Disorders | Acute Lymphoblastic Leukemia | Chronic Myeloid Leukemia | Myelodysplastic Syndrome | Cytopenias | Immune Deficiency | Lymphomas | Bone Marrow Failure | Osteopetrosis | Hemoglobinopathy | Anemia Due to Intrinsic Red Cell Abnormality

United States
Memorial Sloan Kettering Cancer Center

Terminated

TCR Alpha Beta T-cell and CD19 B-cell Depleted Peripheral Blood Stem Cell Transplantation Using the CliniMACS System for Patients With Non-Malignant Hematologic Disorders From Matched or Mismatched, Related or Unrelated Donors

Non-Malignant Hematologic Disorders

United States
Federal Research Institute of Pediatric Hematology...

Completed

TCR Alpha/Beta Depletion for HSCT From Haploidentical and Unrelated Donors in the Treatment of PID

Primary Immune Deficiency Disorder | Hematopoietic Stem Cell Transplantation

Russian Federation
Memorial Sloan Kettering Cancer Center

Terminated

Collection and Generation of Antigen-specific T-lymphocyte Cell Lines From Primary, Third-party, Related, and Unrelated Donors

Healthy

United States
Stanford University

Completed

Stem Cell Transplant From Matched Unrelated or Partially Matched Related Donors

Blood Cancer | Blood and Marrow Transplant (BMT)

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Collection of Bone Marrow From Donors Treated With or Without Filgrastim

No Evidence of Disease | Healthy Stem Cell Donor

United States
University of Calgary
The Canadian Blood and Marrow Transplant Group

Completed

Use of Haploidentical Related Donors for Patients Without Matched Sibling, Unrelated Donor or Cord Blood Units

Hematologic Neoplasms

Canada
National Cancer Institute (NCI)

Completed

Chemotherapy and Unrelated Donor Stem Cell Transplantation for Patients With Cancers of the Blood and Immune System

Multiple Myeloma | Hodgkin's Lymphoma | Acute Leukemia | Myelodysplastic Syndrome | Non-Hodgkin's Disease

United States
Assistance Publique - Hôpitaux de Paris

Unknown

Haploidentical and Mismatched Unrelated Donors Hematopoietic Stem Cell Transplant (ALTERGREF)

Hematopoietic Stem Cell Transplant

France
Stephen Couban
Genzyme, a Sanofi Company

Completed

Healthy Donor Study II - Comparing Plerixafor With G-CSF and Plerixafor

Malignant Lymphoma, Stem Cell Type

Canada
University of Alabama at Birmingham

Terminated

Non-Myeloablative Allogeneic HSCT From HLA Matched Related or Unrelated Donors for the Treatment of Low Grade B Cell Malignancies

Multiple Myeloma | Mantle Cell Lymphoma | Non Hodgkin's Lymphoma | CLL / SLL | Waldenstroms

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Trial of Allogeneic Stem Cell Transplants From HLA Compatible, Related and Unrelated Donors After a Myeloablative Preparative Regimen With Hyperfractionated TBI, Thiotepa and Fludarabine For Adult Patients With Lymphohematopoietic Disorders

Leukemia | Lymphoblastic Lymphoma | Myelodysplastic Syndrome | Paroxysmal Nocturnal Hemoglobinuria (PNH) | Allogeneic Stem Cell Transplant | Non-Hodgkins

United States
Technische Universität Dresden
University Hospital Carl Gustav Carus; Cellex Gesellschaft für Zellgewinnung... and other collaborators

Completed

Plerixafor as a Salvage Regimen to Mobilize Allogeneic Stem Cells in Healthy Volunteers (MOBIL1)

Blood Stem Cell Harvest Failure

Germany
Memorial Sloan Kettering Cancer Center

Completed

Phase II Trial of a Chemotherapy Alone Regimen of IV Busulfan (Busulfex), Melphalan and Fludarabine as Myeloablative Regimen Followed by an Allogeneic T-Cell Depleted Hematopoietic Stem Cell Transplant From an HLA-Identical, or HLA-Non Identical Related or Unrelated Donor

Leukemia | Non-Hodgkin's Lymphoma | Myelodysplastic Syndrome | Allogeneic Marrow Transplant

United States
Sheba Medical Center

Unknown

Carfilzomib for the Prevention of Graft Versus Host Disease

Graft-versus-host Disease

Israel
Heinrich-Heine University, Duesseldorf
Chugai Pharma USA; Terumo BCT

Completed

Two Different Collection Sets for Peripheral Blood Progenitor Cell Apheresis With Spectra Optia® (optiMaL)

Healthy Allogeneic Donors | Granulocyte Colony-stimulating Factor (G-CSF) Mobilized

Germany
Colorado Blood Cancer Institute

Unknown

Fludarabine and 400 CGY Total Body Irradiation for Recipients of HLA-Matched or Mis-Matched Family or Unrelated Donor Hematopoietic Stem Cell Transplants Who Have Rejected Their First Allogeneic Stem Cell Transplant

Graft Failure

United States
Nantes University Hospital

Completed

Natural Killer Index From Hematopoietic Stem Cell Graft

Acute Lymphoblastic Leukemia | Chronic Myeloid Leukemia | Acute Myeloblastic Leukemia

France
University College, London
British Bone Marrow Registry; Anthony Nolan Research Institute

Completed

Study on the Impact of Stem Cell Donation and Bone Marrow Harvesting on Unrelated Donors

Chromosome Aberrations
Terumo BCT
Yale University; Versiti; Key Biologics, LLC; LeukoLab

Completed

Evaluation of the Spectra Optia® Apheresis System Mononuclear Cell (MNC) Collection Procedure in Healthy Blood Donors

Leukapheresis

United States
Etablissement Français du Sang

Completed

Cultured Red Blood Cells : Life Span in Vivo Study (GRc2008)

Healthy Volunteers

France
University of California, San Francisco

Completed

Non-Myeloablative Allogeneic Stem Cell Transplantation With Matched Unrelated Donors for Treatment of Hematologic Malignancies, Renal Cell Carcinoma, and Aplastic Anemia

Follicular Lymphoma | Renal Cell Carcinoma | Acute Myeloid Leukemia | Multiple Myeloma | Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | Chronic Myeloid Leukemia | Aplastic Anemia | Myelodysplasia | NHL | Myeloproliferative Diseases

United States
Samsung Medical Center
Medipost Co Ltd.

Unknown

Umbilical Cord Blood-derived Mesenchymal Stem Cells for the Treatment of Steroid-refractory Acute or Chronic Graft-versus-host-disease (GVHD-MSC)

Graft-Versus-Host Disease | GVHD | Disorder Related to Transplantation | Allogeneic Hematopoietic Transplant

Korea, Republic of
St. Jude Children's Research Hospital

Completed

Stem Cell Transplantation for Patients With Hematologic Malignancies

Juvenile Myelomonocytic Leukemia | Non-Hodgkin Lymphoma | Chronic Myeloid Leukemia | Myelodysplastic Syndrome | Acute Lymphoblastic Leukemias | Acute Myelocytic Leukemia | Hemoglobinuria, Paroxysmal

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
Janssen Research & Development, LLC

Not yet recruiting

Darzalex Faspro (Daratumumab and Hyaluronidase-fihj) Before Standard Desensitization and Allogeneic Peripheral Blood Stem Cell Transplantation in Adult Patients at High-risk for Primary Graft Failure Secondary to Donor Specific Antibodies

Lymphoma | Multiple Myeloma | Hodgkin Lymphoma | Myelofibrosis | Non Hodgkin Lymphoma | Chronic Myeloid Leukemia | Hematologic Malignancy | Aplastic Anemia | Myelodysplastic Syndromes (MDS) | Acute Myeloid Leukemia (AML) | Bone Marrow Transplant Rejection | Acute Lymphoblastic Leukemia (ALL), Adult
Peking University People's Hospital

Not yet recruiting

Kinectics of Donor-specific Anti-HLA Antibody After HLA-incompatible Allogeneic Haematopoietic Stem Cell Transplantation

Haematological Malignancy
Grupo Espanol de trasplantes hematopoyeticos y...

Not yet recruiting

Letermovir (LMV) Prophylaxis in CMV-seronegative Allogeneic Stem Cell Transplant Recipients With CMV Seropositive Donors: an Exploratory Study From Spanish GETH/TC Centers

CMV
New York Stem Cell Foundation Research Institute
Charcot-Marie-Tooth Association

Recruiting

Charcot-Marie-Tooth Disease (CMT) Biological Sample Collection for iPSC Generation and Biobanking

Healthy | Charcot-Marie-Tooth Disease

United States
Ruijin Hospital

Recruiting

Safety and Efficacy of LPE in Clearing DSA in Patients Who Received Allo-HSCT

Leukemia

China

Search clinical trials for: Healthy Unrelated Stem Cell Donors

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Congo

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations