Search clinical trials for: Hepatic function

Total 26764 results

Resolution Therapeutics Limited

Recruiting

Study in Patients With Decompensated Liver Cirrhosis (OPAL)

Liver Cirrhosis

United Kingdom
Medical University of Vienna

Recruiting

Effects of Cross-sex Hormone Treatment on Cardiac Function, Myocardial and Hepatic Fat Content

Gender Dysphoria

Austria
Sun Yat-sen University

Recruiting

FOLFOX-HAIC Plus Lenvatinib and Toripalimab vs. FOLFOX-HAIC Plus Lenvatinib for Advanced Hepatocellular Carcinoma: a Randomized Controlled and Double-blind Trial

Hepatocellular Carcinoma

China
National Atomic Research Institute, Taiwan

Not yet recruiting

A Study of Ga-68 Dolacga to Evaluate Liver Reserve Function in Patients With HCC Before and After Proton Therapy

Hepatic Carcinoma

Taiwan
University Medicine Greifswald

Not yet recruiting

Dose-dependent Kinetics of Thiamin in Healthy Volunteers With and Without Functional OCT1 Hepatic Transporters (THIAMO-1)

Healthy

Germany
Sohag University

Not yet recruiting

Prevelance Of Cutaneous Disorders Among Patients With Heamatologic Malignancies

Dermatologic Disorders With Heamatologic Malignancies Patients

Egypt
NewAmsterdam Pharma
Veranex

Recruiting

PK and Safety in Participants Taking Obicetrapib With Moderate Hepatic Impairment Relative to Normal Hepatic Function

Healthy | Hepatic Impairment

United States
Laval University

Recruiting

Diet Impact on Hepatic Transcriptomics and Lipidomics in Pre-diabetes (DGENE-NAFLD)

Pre-diabetes

Canada
Sohag University

Not yet recruiting

Pulmonary Function Tests Study in Cirrhotic Patients With and Without Hepatocellular Carcinoma

Pulmonary Complications of Liver Cirrhosis and HCC

Egypt
Novo Nordisk A/S

Recruiting

A Research Study Looking at How a Single Dose of the Study Medicine NNC0194-0499 Behaves in Participants With Reduced Liver Function Compared to Participants With Normal Liver Function

Healthy Volunteers | Hepatic Impairment

Germany, Poland, Slovakia
Eli Lilly and Company

Recruiting

A Study of LY3437943 in Participants With Impaired and Normal Liver Function

Hepatic Insufficiency | Healthy

United States
Pfizer

Not yet recruiting

A Study to Learn About the Relationship Between Hepatic Impairment and Myelosuppression (Decreased Bone Marrow Function) in Breast Cancer Patients Treated With the Study Medicine Palbociclib (Pal-bow-sai-klib)

Breast Cancer
Taoyuan General Hospital

Not yet recruiting

Effects of Vitamin D Status and Multiple Mega-dose Supplementation on Health Care Disparities in Perioperative Patients With Hepatocellular Carcinoma Receiving Hepatectomy

Postoperative Complications | Hepatocellular Carcinoma | Liver Function
Pfizer

Recruiting

A Study to Learn About How Loss of Liver Function Affects the Blood Levels of the Study Medicine Called PF-07817883.

COVID-19

United States
Eli Lilly and Company

Recruiting

A Study of LY3502970 in Participants With Impaired and Normal Liver Function

Hepatic Insufficiency | Healthy

United States
Sohag University

Recruiting

Validity of Cow's Milk-related Symptom Score Among Children Suspected to Have Cow's Milk Protein Alergy

Cow's Milk Allergy

Egypt
Daewoong Pharmaceutical Co. LTD.

Recruiting

To Compare the Safety and PK/PD Characteristics of Subjects With Between Hepatic Impairment and Normal Hepatic Function

Diabetes Mellitus, Type 2

Korea, Republic of
Atea Pharmaceuticals, Inc.

Recruiting

Study of Bemnifosbuvir in Subjects With Normal and Impaired Hepatic Function

Hepatic Impairment | Healthy Volunteer

United States
Postgraduate Institute of Medical Education and...

Recruiting

Point-of-Care Echocardiography to Assess Impact of Dynamic Cardiac Function, Renal and Cardiac Biomarkers in Cirrhosis With Refractory Ascites

Acute-On-Chronic Liver Failure | Ascites | Acute Kidney Injury | Cirrhosis, Liver | Refractory Ascites

India
UNICANCER

Recruiting

Testing Immunotherapy for Patients With Liver Cancer and Moderately Altered Liver Functions (HESTIA)

Hepatocellular Carcinoma by BCLC Stage

France
Novo Nordisk A/S

Recruiting

A Research Study Looking at How a Single Dose of the Medicine Cagrilintide Behaves in Participants With Reduced Liver Function and in Healthy Participants With Normal Liver Function

Hepatic Impairment

Germany, Slovakia
Chipscreen Biosciences, Ltd.

Recruiting

Pharmacokinetics of Chiglitazar in Subjects With Hepatic Impairment and Normal Hepatic Function

Hepatic Impairment

China
Tufts University
University of North Carolina, Chapel Hill; Tufts Medical Center

Recruiting

Effects of Vitamin K on Lower-extremity Function in Adults With Osteoarthritis:

Osteo Arthritis Knee

United States
Vanderbilt University Medical Center

Recruiting

Evaluating the Prevalence of Acute Hepatic Porphyria in Postural Tachycardia Syndrome

Postural Orthostatic Tachycardia Syndrome | Acute Hepatic Porphyria

United States
Alexion

Recruiting

Study of ALXN2050 in Participants With Hepatic Impairment

Healthy | Impaired Hepatic Function

United States
Bristol-Myers Squibb

Recruiting

A Study to Evaluate CC-486/Onureg in Participants With Moderate or Severe Hepatic Impairment Compared With Normal Hepatic Function in Participants With Myeloid Malignancies

Hepatic Insufficiency | Neoplasms

Spain, United States, Germany, Argentina, Colombia, Greece
Peking University

Recruiting

Neoadjuvant HAIC of TACE Plus Donafenib in BCLC B Stage HCC: a Multi-center Randomized Controlled Trial.

Hepatocellular Carcinoma

China
Postgraduate Institute of Medical Education and...

Recruiting

Global Coagulation Assessment in Portal Vein Thrombosis and Budd-Chiari Syndrome (Liv-Thrombus)

Portal Vein Thrombosis | Anticoagulants and Bleeding Disorders | Hepatic Vein Thromboses | Hepatic Venous Outflow Obstruction | Portal Hypertension, Noncirrhotic | Portal Vein Occlusion | Portal Vein Embolism | JAK2 Mutation | CALR Gene Mutation | Prothrombin G20210A

India
Sunshine Lake Pharma Co., Ltd.

Not yet recruiting

Pharmacokinetics Study of Larotinib in Subjects With Impaired Hepatic Function

Esophageal Cancer | Advanced Solid Tumor

China
Peking University

Recruiting

Biliary Drainage Plus HAIC in Locally Advanced pCCA

Perihilar Cholangiocarcinoma

China
Shanghai Chest Hospital

Recruiting

Analysis of Drug Resistance in Immune Checkpoint Inhibitors of Non-small Cell Lung Cancer

Non-Small Cell Lung Cancer

China
University of Malaya

Recruiting

Treatment Outcomes For Functional Dyspepsia Based On Current International Guidelines In Multi-Ethnic Asian Patients

Functional Dyspepsia

Malaysia
Peking University Third Hospital

Recruiting

Assessment of Remnant Liver Function in ALPPS by Gd-EOB-DTPA Enhanced MRI

Liver Function Failure | Liver Malignant Tumors

China
Zydus Therapeutics Inc.

Recruiting

Hepatic Impairment, Cholestatic Liver Disease, & NASH With Advanced Fibrosis & Normal Hepatic Function

Hepatic Impairment

United States
Johannes Gutenberg University Mainz
Interdisciplinary Center Clinical Trials (IZKS), University Medical Center...

Recruiting

A Study to Evaluate the Safety, Tolerability and Efficacy of Cabozantinib in Patients With Hepatocellular Carcinoma and Impaired Liver Function (CaboCHILD)

Hepatocellular Carcinoma

Germany
GlaxoSmithKline

Recruiting

A Study of Belantamab Mafodotin in Multiple Myeloma Participants With Normal and Impaired Hepatic Function (DREAMM 13)

Multiple Myeloma

Greece, Korea, Republic of, United States
Epizyme, Inc.
Sponsor GmbH

Recruiting

A Study to Compare the Blood Levels and Safety of Tazemetostat in Participants With Advanced Cancer and Moderate/Severe Liver Impairment to Participants With Advanced Cancer and Normal Liver Function

Hepatic Impairment | Advanced Malignant Solid Tumor

France, Belgium, United States, Poland, Slovakia
Janssen Research & Development, LLC

Recruiting

A Study of Apalutamide in Participants With Severe Hepatic Impairment Compared With Participants With Normal Hepatic Function

Hepatic Impairment

United States
Chinese University of Hong Kong

Recruiting

Safety and Efficacy of Fecal Microbiota Transplantation

Alcohol Dependence | Multiple Sclerosis | Obesity | Diabetes Mellitus | Hepatic Encephalopathy | Irritable Bowel Syndrome | Constipation | Celiac Disease | Crohn Disease | Ulcerative Colitis | Liver Disease | Idiopathic Thrombocytopenic Purpura | Clostridium Difficile Infection | Alopecia | Autism | Multiple Organ Dysfunction... and other conditions

Hong Kong
Baylor Research Institute

Recruiting

Functional Assessment in Liver Transplantation (FrAILT)

End Stage Liver Disease | Cirrhosis

United States
Chinese University of Hong Kong

Recruiting

Microwave Ablation Versus Liver Resection For Early Hepatocellular Carcinoma in Patients With Borderline Liver Function

Carcinoma, Hepatocellular

Hong Kong
Lykos Therapeutics

Not yet recruiting

MDMA in Subjects With Moderate Hepatic Impairment and Subjects With Normal Hepatic Function

Pharmacokinetics | Hepatic Impairment

United States
University of California, San Francisco
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National...

Recruiting

Functional Assessment in Liver Transplantation (FrAILT)

End Stage Liver Disease

United States
University of Washington

Recruiting

Sulfur Colloid SPECT/CT in Measuring Liver Function in Patients With Primary or Metastatic Liver Cancer Undergoing Radiation Therapy or Surgery

Hepatocellular Carcinoma | Intrahepatic Cholangiocarcinoma | Stage IV Liver Cancer | Stage IVA Liver Cancer | Stage IVB Liver Cancer | Vascular Thrombosis

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Radiation Therapy in Treating Patients With Hepatocellular Carcinoma, Cholangiocarcinoma, or Liver Metastasis Who Have Impaired Liver Function

Hepatocellular Carcinoma | Cirrhosis | Cholangiocarcinoma | Metastatic Malignant Neoplasm in the Liver

United States
University of Colorado, Denver

Active, not recruiting

Hepatic Mitochondrial Function in Youth (MANGO)

Obesity | Bariatric Surgery Candidate | Adolescent Obesity | Hepatic Steatosis

United States
Hacettepe University

Active, not recruiting

Evaluation of Frailty and Functional Capacity in End-Stage Liver Disease

End Stage Liver Disease

Turkey
Incyte Corporation

Completed

A Study to Evaluate the Pharmacokinetics and Safety of INCB054707 in Participants With Normal Hepatic Function and Participants With Hepatic Impairment

Kidney Diseases | Renal Insufficiency

United States, Germany
Pfizer

Completed

A Study to Compare How the Study Medicine (PF-07923568) is Processed in Participants With Different Levels of Loss of Liver Function to Healthy Participants.

Liver Diseases | Hepatic Impairment

United States
Eli Lilly and Company

Completed

A Study of Imlunestrant (LY3484356) in Female Participants With Impaired Liver Function

Hepatic Insufficiency | Healthy

United States

Search clinical trials for: Hepatic function

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