Search clinical trials for: High Need High Risk

Total 34101 results

Massachusetts General Hospital
Patient-Centered Outcomes Research Institute; Vanderbilt University Medical... and other collaborators

Not yet recruiting

Annual Wellness Visits vs GRACE-augmented Annual Wellness Visits For Older Adults With High Needs - Phase 1 (SPIRE1)

Healthy Aging | Health Care Utilization | Health-Related Behavior
G. d'Annunzio University

Not yet recruiting

Probiotics in Special Needs Patients at High Risk for Tooth Decay: a Randomized Controlled Trial.

Intellectual Disability | Caries,Dental | Tooth Decay

Italy
National Cancer Institute (NCI)

Not yet recruiting

Acolbifene Versus Low Dose Tamoxifen for the Prevention of Breast Cancer in Premenopausal Women at High Risk for Development of Breast Cancer

Breast Carcinoma | Breast Ductal Carcinoma In Situ | Breast Lobular Carcinoma In Situ | Breast Atypical Hyperplasia

United States
Samsung Medical Center

Not yet recruiting

Routine Versus As-Needed Stress Testing in Asymptomatic Patients With High-Risk Coronary Calcium (SMART-EXAM)

Coronary Atherosclerosis Due to Calcified Coronary Lesion
Ohio State University
DexCom, Inc.; Agency for Healthcare Research and Quality (AHRQ)

Not yet recruiting

Successfully Achieving and Maintaining Euglycemia During Pregnancy for Type 2 Diabetes Through Technology and Coaching

Pregnancy, High Risk | Pre-Gestational Diabetes | Pregnancy in Diabetic | Type2diabetes

United States
Peking Union Medical College Hospital
Tongji Hospital; Beijing Hospital; The First Affiliated Hospital of Xiamen University

Not yet recruiting

A Cohort Study on Screening and Follow-up of High-risk Population of PDAC Based on EUS

Carcinoma, Pancreatic Ductal
VA Office of Research and Development
Veterans Health Administration Office of Primary Care; Veterans Health Administration... and other collaborators

Recruiting

High-Risk Veteran Initiative (RIVET)

Multimorbidity

United States
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI); Seagen Inc.

Recruiting

T-DM1 and Tucatinib Compared With T-DM1 Alone in Preventing Relapses in People With High Risk HER2-Positive Breast Cancer, the CompassHER2 RD Trial

Anatomic Stage IA Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IIIA Breast Cancer AJCC v8 | Anatomic Stage IIIB Breast Cancer AJCC... and other conditions

United States, Canada, Puerto Rico
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Recruiting

Molecular Predictors of Cancer in Patients at High Risk of Lung Cancer

Lung Cancer

United States
Carol Fabian, MD

Recruiting

Protocol for Women at Increased Risk of Developing Breast Cancer

Breast Cancer

United States
M.D. Anderson Cancer Center

Active, not recruiting

Azacitidine, Venetoclax, and Gilteritinib in Treating Patients With Recurrent/Refractory FLT3-Mutated Acute Myeloid Leukemia, Chronic Myelomonocytic Leukemia, or High-Risk Myelodysplastic Syndrome/Myeloproliferative Neoplasm

Recurrent Acute Myeloid Leukemia | Recurrent Chronic Myelomonocytic Leukemia | Refractory Acute Myeloid Leukemia | Refractory Chronic Myelomonocytic Leukemia | Recurrent Myelodysplastic/Myeloproliferative Neoplasm | Refractory Myelodysplastic/Myeloproliferative Neoplasm

United States
LIB Therapeutics LLC
Medpace, Inc.

Active, not recruiting

Study of Long-Term Efficacy and Safety of LIB003 in CVD or High Risk for CVD Patients Needing Further LDL-C Reduction (LIBerate-HR)

Cardiovascular Diseases | Hypercholesterolemia | Cardiovascular Risk Factor | Cardiovascular Stroke

United States, Israel, India
Maastricht University Medical Center

Active, not recruiting

Needs and Preferences of Patients With Head-neck Cutaneous SCC

Squamous Cell Carcinoma of the Head and Neck | Squamous Cell Carcinoma of Head and Neck | Skin Cancer | Patient Satisfaction | Decision Making | Squamous Cell Carcinoma | Cutaneous Squamous Cell Carcinoma of the Head and Neck | Cutaneous Squamous Cell Carcinoma | High-Risk Cancer | Preference, Patient | I...

Netherlands
Norwegian Institute of Public Health
University of Oslo; Oslo University Hospital; Oslo Municipality

Active, not recruiting

Does the New Fall- and Fracture Prevention Initiative in Oslo Have Effect?

Hip Fractures | Fall Injury
Sahlgrenska University Hospital, Sweden
NU-Hospital Organization, Sweden

Active, not recruiting

Standardized Perioperative Management of Patients Operated With Acute Abdominal Surgery in a High-risk Emergency Setting (SMASH)

Peritonitis | Ileus | Laparotomy | Acute Abdomen | Perforated Bowel

Sweden
Medtronic Cardiovascular

Completed

Safety and Efficacy Continued Access Study of the Medtronic CoreValve® System in the Treatment of Symptomatic Severe Aortic Stenosis in Very High Risk Subjects and High Risk Subjects Who Need Aortic Valve Replacement

Severe Aortic Stenosis

United States
Medtronic Cardiovascular

Completed

Safety and Efficacy Study of the Medtronic CoreValve® System in the Treatment of Symptomatic Severe Aortic Stenosis in High Risk and Very High Risk Subjects Who Need Aortic Valve Replacement

Severe Aortic Stenosis

United States
Johns Hopkins University

Withdrawn

High Risk Outpatient Intern-led Care (HeROIC) Clinic Initiative

Emergencies | Risk Reduction | Comorbidities and Coexisting Conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Withdrawn

Lurbinectedin With or Without Irinotecan in Treating Patients With Relapsed or High Risk Metastatic Ewing Sarcoma

Recurrent Ewing Sarcoma | Metastatic Ewing Sarcoma

United States
Miami VA Healthcare System

Enrolling by invitation

Inter-Disciplinary Outpatient Care Model Providing Comprehensive Geriatric Assessment, Care-Coordination & Co-management (C4)

Geriatric Assessment | Veterans | Care-Coordination | Outpatient Care

United States
Nanfang Hospital of Southern Medical University
Changhai Hospital; LanZhou University; Beijing 302 Hospital; Sheffield Teaching... and other collaborators

Unknown

Detachable String Magnetically Controlled Capsule Endoscopy for Detecting High-risk Varices in Compensated Cirrhosis

Compensated Cirrhosis | Gastroesophageal Varices Bleeding

China, United Kingdom
Boston Medical Center
Centers for Disease Control and Prevention

Completed

A Medical Home-Based Intervention to Prevent Child Neglect in High-Risk Families

Child Abuse

United States
CareMore Health, San Bernardino

Unknown

Intensive Management of At-risk Patients

Chronic Disease
National Institute of Dental and Craniofacial Research...

Completed

Oral Health Needs Assessment of Sjogren s Syndrome and Salivary Gland Dysfunction Cohorts and Healthy Volunteers Evaluating Oral Health Disparities as Determinants of Oral Health in a High-Risk Population

Sjogren's Syndrome | Oral Health

United States
Carol Fabian, MD
Intergenetics, Inc.

Withdrawn

Protocol for Postmenopausal Women at Increased Risk of Developing Breast Cancer

Breast Cancer

United States
Eisai Inc.
Thrombolysis In Myocardial Infarction (TIMI) Academic Research Organization

Completed

A Study to Evaluate the Effect of Long-term Treatment With BELVIQ (Lorcaserin HCl) on the Incidence of Major Adverse Cardiovascular Events and Conversion to Type 2 Diabetes Mellitus in Obese and Overweight Subjects With Cardiovascular Disease or Multiple Cardiovascular Risk Factors (CAMELLIA-TIMI)

Obesity | Cardiovascular Disease | Overweight | Type 2 Diabetes | High Cardiovascular Risk

United States, Canada, Poland, Australia, Mexico, New Zealand, Bahamas, Chile
Pfizer

Terminated

The Evaluation of Bococizumab (PF-04950615; RN316) in Reducing the Occurrence of Major Cardiovascular Events in High Risk Subjects (SPIRE-2)

Cardiovascular Disease

United States, Finland, Netherlands, Spain, Belgium, Germany, Czechia, Switzerland, Denmark, Australia, United Kingdom, Korea, Republic of, Hungary, Israel, Poland, Taiwan, Mexico, Turkey, Ireland, Canada, New Zealand, South Africa, Brazi... and more
Celgene

Completed

Evaluate Risk/Benefit of Nab Paclitaxel in Combination With Gemcitabine and Carboplatin Compared to Gemcitabine and Carboplatin in Triple Negative Metastatic Breast Cancer (or Metastatic Triple Negative Breast Cancer) (tnAcity)

Breast Cancer | Metastatic Breast Cancer | Stage IV Breast Cancer | Triple-negative Breast Cancer | Recurrent Breast Cancer | Breast Tumor | Cancer of the Breast | Triple-negative Metastatic Breast Cancer | Estrogen Receptor- Negative Breast Cancer | HER2- Negative Breast Cancer | Progesterone Receptor- Negative...

United States, United Kingdom, Italy, Germany, Spain, Canada, Portugal, Australia, Austria, Greece, Brazil, France
Mackay Memorial Hospital

Completed

Nutritional Needs and Intake on Clinical Outcomes in Mechanically Ventilated Critically Ill Elderly Patients

Critical Illness | Elderly | Mechanical Ventilation

Taiwan
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

C-11 Choline PET-CT Scan in Finding Metastases in Patients With Newly Diagnosed High-Risk Prostate Cancer

Prostate Cancer

United States
University of Washington
National Cancer Institute (NCI)

Completed

Sorafenib Tosylate and Gene Expression Analysis in Patients Undergoing Surgery For High-Risk Localized Prostate Cancer

Stage II Prostate Cancer | Stage III Prostate Cancer | Adenocarcinoma of the Prostate

United States
Helse Stavanger HF
Abbott; Nordsjørittet

Active, not recruiting

The North Sea Race Endurance Exercise Study (NEEDED)

Healthy

Norway
Boston Medical Center
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Completed

Project HERMITAGE: HIV Prevention in Hospitalized Russian Drinkers

HIV Infections

Russian Federation
San Diego State University

Completed

Latinos Understanding the Need for Adherence (LUNA)

Type 2 Diabetes Mellitus | Atherosclerosis | Hypercholesterolemia | Heart Disease | High Blood Pressure

United States
Carol Fabian, MD
BTR Group

Completed

Modulation of Breast Cancer Risk Biomarkers by High Dose Vitamin D

Breast Cancer

United States
Carol Fabian, MD
Novartis

Completed

Protocol for Women at Increased Risk of Developing Breast Cancer

Breast Cancer

United States
CureVac

Terminated

An Open Label Randomised Trial of RNActive® Cancer Vaccine in High Risk and Intermediate Risk Patients With Prostate Cancer

Prostate Carcinoma

Germany
Hillel Yaffe Medical Center

Unknown

Neonatal Sepsis Workup for High Risk Newborns - Evaluation of Need and Ways to Prevent

Neonatal Sepsis

Israel
Fox Chase Cancer Center
National Cancer Institute (NCI)

Withdrawn

Comparison of Biomarkers Based on Fine-Needle Aspiration in Women at Increased or Normal Risk of Breast Cancer

Breast Cancer
Children's Cancer and Leukaemia Group

Withdrawn

High-Dose Iodine I 131 Metaiodobenzylguanidine, Topotecan, and Peripheral Stem Cell Transplant in Treating Young Patients With Relapsed Stage 4 Neuroblastoma or Primary Resistant High-Risk Neuroblastoma

Neuroblastoma
National Cancer Institute (NCI)

Completed

A Pilot Trial of Tamoxifen and 4-HPR (4-N-Hydroxyphenyl Retinamide) in Persons at High Risk for Developing Breast Cancer

Breast Cancer | Breast Neoplasms

United States
Peking Union Medical College
China-Japan Friendship Hospital

Not yet recruiting

Impact of Multi-Component Interventions on High Risk COPD Population

Chronic Obstructive Pulmonary Disease | Multimorbidity | Population Medicine
Peking Union Medical College
China-Japan Friendship Hospital

Not yet recruiting

Impact of Multi-Component Interventions on High-Risk COPD Smokers

Tobacco Use Cessation | Multimorbidity | Digital Health Intervention | Multi-component Intervention
Ruijin Hospital

Not yet recruiting

The Efficacy of Allogeneic Hematopoietic Stem Cell Transplantation in Newly Diagnosed High-relapse-risk CEBPA Mutant Acute Myeloid Leukemia

Acute Myeloid Leukemia

China
Chengdu Zenitar Biomedical Technology Co., Ltd

Recruiting

Flunotinib Maleate Phase II Intermediate-High Risk Bone Fiber Clinical Trial

MF,PMF,PPV-MF,PET-MF

China
Peking Union Medical College
China-Japan Friendship Hospital

Not yet recruiting

Impact of Multi-component Interventions on Populations With Mental Health Symptoms and High-risk COPD

Multimorbidity | Mental Health Issue | Multi-component Interventions
Ruijin Hospital

Not yet recruiting

The Efficacy of Allo-HSCT in ND HR-CBF-AML

Acute Myeloid Leukemia

China
Fudan University

Recruiting

Short-course Radiotherapy Combined With CapeOx and PD-1 Inhibitor After Local Excision for High-risk Early Rectal Cancer (TORCH-LE)

Rectal Cancer

China
Qilu Hospital of Shandong University

Recruiting

Adjuvant Adebrelimab Plus Apatinib for Participants With HCC at High-risk of Recurrence After Curative Resection

Carcinoma, Hepatocellular

China
Maria Sklodowska-Curie National Research Institute...

Not yet recruiting

177Lu-PSMA as a Systemic Adjuvant Treatment in Patients With High and Very High Risk Prostate Cancer (PSMA-ADJUVO)

Prostate Cancer

Search clinical trials for: High Need High Risk

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