Search clinical trials for: Hippocampal Avoidance Whole Brain Radiotherapy

Total 43588 results

Fudan University

Recruiting

WBRT With Hippocampal-avoidance Technique Followed by SRT for Extensive-stage SCLC With Baseline Brain Metastases

Brain Metastases | SCLC,Extensive Stage

China
National Taiwan University Hospital

Recruiting

Neurocognitive Outcome of Bilateral or Unilateral Hippocampal Avoidance WBRT With Memantine for Brain Metastases

Metastatic Malignant Neoplasm to Brain

Taiwan
Chang Gung Memorial Hospital

Recruiting

Neurocognitive Impact and Dose-Effect Relationship of Hippocampal Avoidance During Whole Brain Radiotherapy Plus Simultaneous Integrated Boost - A Prospective Follow-up Study

Brain Metastasis | Brain Metastases

Taiwan
Chang Gung Memorial Hospital

Recruiting

A Prospective Study of the Impact of Hippocampal Avoidance During Whole Brain Radiotherapy on Neurocognitive Function Decline

Brain Metastasis | Brain Metastases

Taiwan
NRG Oncology
National Cancer Institute (NCI); Radiation Therapy Oncology Group

Active, not recruiting

Whole-Brain Radiation Therapy With or Without Hippocampal Avoidance in Treating Patients With Limited Stage or Extensive Stage Small Cell Lung Cancer

Extensive Stage Small Cell Lung Carcinoma | Limited Stage Small Cell Lung Carcinoma

United States, Canada
Washington University School of Medicine
Varian Medical Systems

Completed

Simulation-Free Hippocampal-Avoidance Whole Brain Radiotherapy Using Diagnostic MRI-Based and Cone Beam Computed Tomography-Guided On-Table Adaptive Planning in a Novel Ring Gantry Radiotherapy Device

Intracranial Metastatic Disease From Any Solid Malignancy

United States
NRG Oncology
National Cancer Institute (NCI)

Completed

Memantine Hydrochloride and Whole-Brain Radiotherapy With or Without Hippocampal Avoidance in Reducing Neurocognitive Decline in Patients With Brain Metastases

Cognitive Impairment | Metastatic Malignant Neoplasm in the Brain | Solid Neoplasm

United States, Canada
National Taiwan University Hospital

Unknown

Neurocognitive Outcome of Conformal WBRT w/wo Hippocampal Avoidance for Brain Metastases

Metastatic Malignant Neoplasm to Brain

Taiwan
Kaohsiung Medical University Chung-Ho Memorial...

Unknown

Memory Preservation of Hippocampal Avoidance Whole Brain Radiotherapy

Brain Metastases | Neurocognitive Function

Taiwan
Affiliated Hospital to Academy of Military Medical...

Unknown

Hippocampal-sparing Whole Brain Radiotherapy for Brain Metastases From Breast Cancer

Brain Metastases | Breast Cancer Metastatic

China
Medical University Innsbruck

Recruiting

HA-WBRT vs SRS in Patients With Multiple Brain Metastases (HipSter)

Brain Metastases

Austria
Canadian Cancer Trials Group
Alliance for Clinical Trials in Oncology; NRG Oncology

Recruiting

Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5 or More Brain Metastases

Brain Metastases

Canada, United States
Dana-Farber Cancer Institute
Brigham and Women's Hospital

Recruiting

Hippocampal Sparing Whole Brain Radiation Versus Stereotactic Radiation in Patients With 5-20 Brain Metastases: A Phase III, Randomized Trial

Brain Metastases

United States
University College, London
Cancer Research UK; The Brain Tumour Charity

Completed

Hippocampal Sparing Whole Brain Radiotherapy vs Conventional Whole Brain Radiotherapy in Patients With Brain Metastases (HIPPO)

Brain Metastases

United Kingdom
University of Texas Southwestern Medical Center

Completed

Hippocampal-Avoiding Whole Brain Irradiation With Simultaneous Integrated Boost for Treatment of Brain Metastases

Brain Neoplasms, Adult, Malignant

United States
Institut Paoli-Calmettes

Completed

Evaluation of the Efficacy of Hippocampal Avoidance on the Cognitive Toxicity of Whole-Brain Radiation Therapy After Surgical Resection of Single Brain Metastasis of Breast Cancer

Breast Cancer | Brain Metastasis

France
Sun Yat-sen University
Fifth Affiliated Hospital, Sun Yat-Sen University

Unknown

A Clinical Trial on Whole-brain Radiotherapy With Temozolomide Concurrent Chemotherapy or Avoidance of Hippocampus for Patients of Brain Metastases

Brain Metastasis | Radiation Therapy Complication

China
Sheba Medical Center

Unknown

Neurocognitive Function After Prophylactic Cranial Irradiation & Hippocampal Sparing in LD SCLC Patients - a Pilot Study

Carcinoma, Small Cell

Israel
Sichuan University

Recruiting

Safety and Efficacy of Whole Brain LDRT+ICI+Intrathecal Chemotherapy in Refractory Meningeal Metastasis of Lung Cancer

NSCLC | PD-1 Inhibitor | Leptomeningeal Metastasis | Low Dose Radiotherapy

China
Emory University
National Cancer Institute (NCI)

Not yet recruiting

Arginine and Whole Brain Radiation Therapy for the Treatment of Patients With Brain Metastases

Metastatic Malignant Solid Neoplasm | Metastatic Malignant Neoplasm in the Brain

United States
Chang Gung Memorial Hospital

Not yet recruiting

Cognition-preserving Brain Irradiation for Treating Patients With Intracranial Meningioma in the Era of Modern Radiotherapeutic Techniques Including Proton Beam Therapy - a Prospective Study Focusing on Radiological Outcomes and Neurocognitive Endpoints

Intracranial Meningioma

Taiwan
Chang Gung Memorial Hospital

Not yet recruiting

HF-SRT vs. HS-WBRT in Treating Patients With Brain Oligometastases

Brain Oligometastases

Taiwan
Xiaorong Dong

Not yet recruiting

Circulating Tumor DNA and T Cell Repertoire Predict Radiotherapeutic Outcomes in NSCLC Patients With Brain Metastasis

Carcinoma, Non-Small-Cell Lung | Brain Metastases

China
ImmunoChem Therapeutics, LLC
National Cancer Institute (NCI); Northwestern Medicine

Recruiting

MW151 and Whole-brain Radiotherapy in Patients With Intracranial Metastases (MW151-102)

Cognitive Dysfunction, Cognitive Disorder

United States
University Hospital Heidelberg

Recruiting

The CyberChallenge Trial How Much is Too Much - What is the Role of Cyberknife Radiosurgery in Patients With Multiple Brain Metastases? (CyberChallenge)

Brain Metastases | Nsclc

Germany
Tata Memorial Hospital

Recruiting

Observation or Upfront Cranial RT in Oncogene Mutated NSCLC With Asymptomatic BM: A Phase III RCT

Asymptomatic Brain Metastases | Driver Mutation Positive Non-small Cell Lung Cancer

India
Ottawa Hospital Research Institute

Not yet recruiting

Hippocampal-Sparing Stereotactic Radiosurgery Treatment of Brain Metastases Using CyberKnife (HiSparCK)

Brain Metastases | Radiosurgery
Postgraduate Institute of Medical Education and...

Recruiting

Stereotactic Radiosurgery vs Whole Brain Radiotherapy in Breast Cancer With Brain Oligometastasis (SRSvsWBRT)

Breast Cancer | Brain Metastases, Adult | Stereotactic Radiosurgery | Whole Brain Radiotherapy

India
Chongqing University Cancer Hospital

Recruiting

Almonertinib Combined With Cerebral Radiation Treat Brain Metastases From EGFR Positive NSCLC

Non-Small Cell Lung Cancer (NSCLC)

China
Dana-Farber Cancer Institute
NH TherAguix SAS

Recruiting

Stereotactic Brain-directed Radiation With or Without Aguix Gadolinium-Based Nanoparticles in Brain Metastases

Melanoma | Breast Cancer | Colorectal Cancer | Lung Cancer | Brain Cancer | Brain Tumor | HER2-positive Breast Cancer | Gastrointestinal Cancer | Brain Metastases | SRS | SRT | Whole Brain Radiation | Stereotactic Radiation | AGuIX | Nanoparticle | Cystic

United States
Mediterranean Institute of Oncology
University of Palermo; University of Messina

Recruiting

WHOle Brain Irradiation or STEreotactic Radiosurgery for Five or More Brain Metastases (WHOBI-STER) (WHOBI-STER)

Quality of Life | Neurocognitive Deficit | Activities of Daily Living

Italy
NRG Oncology
National Cancer Institute (NCI)

Recruiting

Testing if High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids the Hippocampus is Better at Preventing Loss of Memory and Thinking Ability

Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Metastatic Malignant Neoplasm in the Brain | Metastatic Lung Small Cell Carcinoma | Recurrent Lung Small Cell Carcinoma

United States, Canada
NRG Oncology
National Cancer Institute (NCI)

Recruiting

Testing the Addition of Whole Brain Radiotherapy Using a Technique That Avoids the Hippocampus to Stereotactic Radiosurgery in People With Cancer That Has Spread to the Brain and Come Back in Other Areas of the Brain After Earlier Stereotactic Radiosurgery

Metastatic Renal Cell Carcinoma | Metastatic Lung Non-Small Cell Carcinoma | Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Anatomic Stage IV Breast Cancer AJCC v8 | Prognostic Stage IV Breast Cancer AJCC v8 | Metastatic Melanoma | Stage IV Lung Cancer AJCC v8 | Stage IV Renal Cell... and other conditions

United States
Chang Gung Memorial Hospital

Recruiting

Prospective Neurobehavioral Functions in Newly-diagnosed Patients With Primary CNS Lymphoma Treated With Hyperfractionated Conformal Whole-brain Radiation Therapy Plus Simultaneous Integrated Boost

Primary CNS Lymphoma | Brain Lymphoma

Taiwan
University Hospital, Grenoble
NH TherAguix SAS

Recruiting

Radiotherapy of Multiple Brain Metastases Using AGuIX® (NANORAD2)

Radiotherapy | Brain Metastases, Adult

France
Lawrence D Recht
Sanofi

Recruiting

Whole Brain Radiation Therapy With Standard Temozolomide Chemo-Radiotherapy and Plerixafor in Treating Patients With Glioblastoma

Glioblastoma | Malignant Glioma | Gliosarcoma | Glioblastoma With Primitive Neuronal Component | Oligodendroglial Component Present

United States
M.D. Anderson Cancer Center

Active, not recruiting

Nivolumab and Radiation Therapy With or Without Ipilimumab in Treating Patients With Brain Metastases From Non-small Cell Lung Cancer

Metastatic Malignant Neoplasm in the Brain | Stage IV Non-Small Cell Lung Cancer AJCC v7

United States
BioMimetix JV, LLC
National Cancer Institute (NCI); Duke Cancer Institute

Terminated

A Trial for Treatment of Cancer Patients With Multiple Brain Metastases Undergoing Whole-Brain Radiotherapy

Multiple Brain Metastases

United States
National Cancer Institute (NCI)

Active, not recruiting

Ropidoxuridine and Whole Brain Radiation Therapy in Treating Patients With Brain Metastases

Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm | Metastatic Malignant Neoplasm in the Brain

United States
National Cancer Institute (NCI)

Active, not recruiting

Trametinib With or Without Whole Brain Radiation Therapy in Treating Patients With Brain Metastases

Metastatic Malignant Neoplasm in the Brain

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing the Safety of M6620 (VX-970) When Given With Standard Whole Brain Radiation Therapy for the Treatment of Brain Metastases From Non-small Cell Lung Cancer, Small Cell Lung Cancer, or Neuroendocrine Tumors

Metastatic Lung Non-Small Cell Carcinoma | Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Metastatic Lung Neuroendocrine Neoplasm | Metastatic Malignant Neoplasm in the Brain | Metastatic Lung Small Cell Carcinoma

United States
National Cancer Centre, Singapore
Singapore General Hospital; Singhealth Duke-NUS Oncology Academic Clinical...

Active, not recruiting

Phase 2 Trial in Multiple Brain Metastases Outcomes With HA-SIB-WBRT

Brain Metastases

Singapore
Sidney Kimmel Cancer Center at Thomas Jefferson...
Bristol-Myers Squibb

Completed

Phase I Study of Ipilimumab Combined With Whole Brain Radiation Therapy or Radiosurgery for Melanoma

Recurrent Melanoma | Stage IV Melanoma | Tumors Metastatic to Brain

United States
Cancer Institute and Hospital, Chinese Academy...

Completed

HA-WBRT-SIB for Brain Metastasis of Lung Cancer

Cognitive Function | Brain Metastases | Lung Neoplasm | Simultaneous Integrated Boost | Hippocampal Avoidance

China
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Stereotactic Radiosurgery or Whole Brain Radiation Therapy in Treating Patients With Newly Diagnosed Non-melanoma Brain Metastases

Metastatic Malignant Neoplasm in the Brain | Metastatic Malignant Neoplasm

United States
H. Lee Moffitt Cancer Center and Research Institute
Pfizer

Active, not recruiting

Avelumab With Radiotherapy in Patients With Leptomeningeal Disease

Leptomeningeal Metastases | Leptomeningeal Disease

United States
Instituto Nacional de Cancerologia de Mexico

Terminated

Study of Whole-brain Irradiation With Chloroquine for Brain Metastases (CLQ)

Brain Metastasis

Mexico
New Mexico Cancer Care Alliance

Completed

Whole Brain Radiation Using IMRT for Patients With Brain Metastases

Neoplasm Metastasis | Central Nervous System Metastases

United States
Juergen Debus
Heidelberg University

Completed

Whole Brain Radiation Therapy Alone vs. Radiosurgery for SCLC Patients With 1-10 Brain Metastases (ENCEPHALON)

SCLC | Brain Metastases

Germany
University Hospital Heidelberg

Suspended

Supportive Care With or Without Repeated Whole Brain Radiotherapy in Patients With Recurrent Brain Metastases (RECARE)

Brain Metastases

Germany

Search clinical trials for: Hippocampal Avoidance Whole Brain Radiotherapy

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