Search clinical trials for: Hyperlipoproteinemia(a)

Total 471746 results

Silence Therapeutics plc
Medpace, Inc.

Completed

Study to Investigate Safety, Tolerability, PK and PD Response of SLN360 in Subjects With Elevated Lipoprotein(a)

Dyslipidemias | Hyperlipidemias | Elevated Lp(a)

United States, Australia, United Kingdom, Netherlands
Akcea Therapeutics
Ionis Pharmaceuticals, Inc.

Completed

Phase 2 Study of ISIS 681257 (AKCEA-APO(a)-LRx) in Participants With Hyperlipoproteinemia(a) and Cardiovascular Disease

Cardiovascular Disease | Elevated Lipoprotein(a)

United States, Canada, Denmark, Germany, Netherlands
Charite University, Berlin, Germany

Withdrawn

Randomized Controlled Trial of Lipid Apheresis in Patients With Elevated Lipoprotein(a) (ELAILa)

Hyperlipoproteinemia(a) | Progressive Cardiovascular Disease

Germany
Novartis Pharmaceuticals

Active, not recruiting

A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Rate of Weekly Lipoprotein Apheresis Sessions in Patients With Hyperlipoproteinemia(a) and Established Cardiovascular Disease in Germany

Hyperlipoproteinemia(a)

Germany
Novartis Pharmaceuticals

Recruiting

An Open Label Extension (OLE) Study to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230) (OLE)

Hyperlipoproteinemia (a)

Germany
Technische Universität Dresden
Kaneka Pharma Europe N.V.

Recruiting

Effect of Lipoprotein(a) Elimination by Lipoprotein Apheresis on Cardiovascular Outcomes (MultiSELECt)

Lipoprotein Types--Lp System Lp(A) Hyperlipoproteinemia

Germany
Changi General Hospital

Not yet recruiting

Elevated Lipoprotein(a) in Hospital Staff (LPACO)

Cardiovascular Diseases | Hypercholesterolemia | Lipoprotein Types--Lp System Lp(A) Hyperlipoproteinemia

Singapore
Novartis Pharmaceuticals

Recruiting

A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosis

Aortic Stenosis

Switzerland, Canada, Israel, United States, United Kingdom
Fresenius Medical Care Deutschland GmbH

Completed

Safety and Efficacy of the DALI LDL-adsorber and MONET Lipoprotein Filter (LINET)

Hypercholesterolemia, Familial | LIPOPROTEIN TYPES--Lp SYSTEM Lp(a) HYPERLIPOPROTEINEMIA

Germany
Jubilee Mission Medical College and Research Institute
Christian Medical College, Vellore, India

Active, not recruiting

Effect of a Customised Lifestyle Medicine Strategy on Lowering Blood Lipid Levels in Indian Physicians (CLIP)

Hypertension | BMI | Cholesterol, Elevated | Lifestyle Risk Reduction | LDL Hyperlipoproteinemia | HbA1C | Lipoprotein(A)

India
DynPort Vaccine Company LLC, A GDIT Company

Completed

Study to Evaluate the Safety, Tolerability and Immunogenicity of Recombinant Botulinum Vaccine A/B in Healthy Adults

RECOMBINANT BOTULINUM VACCINE A/B

United States
Amsterdam Molecular Therapeutics
ICON plc

Terminated

Duration of Effect of Alipogene Tiparvovec Treatment, Which Was Administered in Other Studies

Hyperlipoproteinemia Type I

Canada
University of Texas Southwestern Medical Center

Completed

Orlistat for the Treatment of Type I Hyperlipoproteinemia (T1HLP)

Hypertriglyceridemia | Hyperlipoproteinemia Type I

United States
Duke University

Completed

Comparison of Topical Skin Adhesive to Subcuticular Suture Closure of Implantable Port Incisions

Port-A-Cath Placement | Octylcyanoacrylate

United States
AstraZeneca

Completed

Effect of Rosuvastatin on Triglyceride Levels in Mexican Hypertriglyceridemic Patients

Hypertriglyceridemia | Hyperlipidemia | Hyperlipoproteinemia Type V | Hyperlipoproteinemia Type IV | Hyperlipoproteinemia Type IIb

Mexico
Novartis Pharmaceuticals

Completed

A Randomized, Double-blind, Placebo Controlled Study to Assess Efficacy, Safety and Tolerability of LCQ908 in Subjects With Familial Chylomicronemia Syndrome

Familial Chylomicronemia Syndrome (FCS)

South Africa, Spain, France, Germany, United Kingdom, United States, Canada, Netherlands
Aristotle University Of Thessaloniki

Recruiting

Association of Single Nucleotide Polymorphisms (SNPs) in Metalloproteinases (MMPs) Genes With the Risk of Primary Knee Osteoarthritis in Greek Population.

Metalloproteinase SNPs -1575 G/A MMP-2, 836 A/G MMP-9 and -77 A/G MMP-13 and Risk for Developing Knee Osteoarthritis in Greek Population

Greece
Merz Pharmaceuticals GmbH

Completed

A Study to Evaluate the Distribution of Botulinum Neurotoxin Type A Administered as Intradermal Injections, Comparing Different Doses, Concentrations, and Delivery Methods

N/A, as no Specific Medical Condition Will be Treated

Germany
University of Texas Southwestern Medical Center

Recruiting

Long Term Efficacy and Safety of Orlistat for Type 1 Hyperlipoproteinemia

Type 1 Hyperlipoprotenemia

United States
S.LAB (SOLOWAYS)
Center of New Medical Technologies; Triangel Scientific

Completed

Evaluating the Impact of Omega-3 Fatty Acid Supplementation (Soloways™) on Lipid Profiles in Adults With PPARG Polymorphisms (SOLIPARG)

LDL Hyperlipoproteinemia | Low-Density-Lipoprotein-Type [LDL] Hyperlipoproteinemia | Triglyceride Storage Type I or II Disease

Russian Federation
Novartis Pharmaceuticals

Completed

Safety, Tolerability,Pharmacokinetics(PK)and Pharmacodynamics(PD)Assessment of LCQ908 in Patients With Severe Hypertriglyceridemia

Hyperlipoproteinemia

Canada
Nina Hermans
University Hospital, Antwerp

Recruiting

Extracts of Amla, Walnut Leaf, Red Yeast Rice and Olive in Cardiovascular Prevention (AmWaRO)

Low-Density-Lipoprotein-Type [LDL] Hyperlipoproteinemia

Belgium
University Hospital Ostrava

Completed

The Impact of the COVID-19 Pandemic on Cardiovascular Risk Factors in Patients With Diabetes (ICOVdia)

Diabetes Mellitus | Covid19

Czechia
PHAC/CIHR Influenza Research Network
GlaxoSmithKline; CHU de Quebec-Universite Laval; The Ottawa Hospital; Hamilton... and other collaborators

Completed

Surveillance for Adverse Events Following Pandemic H1N1 Immunization

Novel Influenza A/H1N1
Assiut University

Unknown

Managment of Cardiorespiratory Arrest (clinicalaudit)

Assess the Quality Ofmanagement of Children With Cardiorespiratory Arrest in Assuit University Children Hospital According to the( A H A)Guidelines
University of Texas Southwestern Medical Center

Terminated

Phase 2 Study of Orlistat and SLx-4090 for the Treatment of Type 1 Hyperlipoproteinemia

Type 1 Hyperlipoproteinemia

United States
Saint-Joseph University

Unknown

Red Rice Yeast in Low-density Lipoprotein (LDL) Lowering: an Efficacy Study

Dyslipidemias | LDL Hyperlipoproteinemia

Lebanon
National Institute of Environmental Health Sciences...

Withdrawn

BPA Biomonitoring Study in Cashiers

Bisphenol A
UniQure Biopharma B.V.

Completed

Glybera Registry, Lipoprotein Lipase Deficient (LPLD) Patients (GENIALL)

Lipoprotein Lipase Deficiency | Familial Hyperlipoproteinemia Type 1 | Familial Hyperchylomicronemia

Germany
Swansea University

Completed

Study Protocol for a Feasibility Study of a Novel ACT-based eHealth Psychoeducational Intervention for Students With Mental Distress

A Bite of ACT' (BOA) Acceptance and Commitment Therapy Online Psychoeducation Course | A Wait-list Control

United Kingdom
Cheikh Anta Diop University, Senegal
International Atomic Energy Agency

Not yet recruiting

Kinetics of Retinol and TBS Among Lactating Senegalese Women Living in an Urban Setting and the Relationship Between Their TBS and Those of Their Infants (TBS)

Vitamin A

Senegal
Hospices Civils de Lyon

Completed

FH Detection in Children by Salivary Test (DEPEDIACOL)

Hyperlipoproteinemia Type II

France
Nordic Pharma, USA
Nutrasource Pharmaceutical and Nutraceutical Services, Inc.

Withdrawn

Efficacy Study of Daily Pro-Omega LDL for Low-Density Lipoprotein Cholesterol and Triglyceride Reduction (PrOteCT)

Mixed Hyperlipoproteinemia
Coopervision, Inc.

Completed

Clinical Evaluation of Two Silicone Hydrogel Contact Lenses

Myopia

United Kingdom
Coopervision, Inc.

Completed

Evaluation of the Performance of Monthly Replacement Sphere Lens Designs in Habitual Soft Contact Lens Wearers

Myopia | Hyperopia

United States
University of California, Davis
Bill and Melinda Gates Foundation; Penn State University; Newcastle University; Helen Keller International and other collaborators

Completed

Vitamin A Status and Risk of Excessive Vitamin A Intake Among Urban Filipino Children (GloVitAS-P)

Vitamin A Status

Philippines
Coopervision, Inc.
CORE

Completed

Evaluation of Monthly Replacement Lenses in Habitual Soft Contact Lens Wearers Who Report Frequent Digital Devise Use

Ametropia

United States, Canada
Ionis Pharmaceuticals, Inc.
Akcea Therapeutics

Completed

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of IONIS APO(a)-LRx in Healthy Volunteers With Elevated Lipoprotein(a)

Elevated Lipoprotein(a)

Canada
Ionis Pharmaceuticals, Inc.

Completed

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ISIS-APO(a)Rx in Participants With High Lipoprotein(a)

Elevated Lipoprotein(a)

Netherlands, United Kingdom, Denmark, Germany, Canada
Coopervision, Inc.
CORE

Completed

Performance Evaluation of Two Silicone Hydrogel Toric Lens Designs in Habitual Soft Contact Lens Wearers

Astigmatism

United States, Canada
Bioverativ Therapeutics Inc.

Completed

Long-Term Safety and Efficacy of rFVIIIFc in the Prevention and Treatment of Bleeding Episodes in Previously Treated Participants With Hemophilia A (ASPIRE)

Hemophilia A

United States, Canada, Italy, Australia, Austria, Belgium, Brazil, France, Germany, Hong Kong, India, Ireland, Israel, Japan, Netherlands, New Zealand, Poland, South Africa, Spain, Sweden, Switzerland, United Kingdom
Xention Ltd

Completed

A Study on the Effects of TA-8995 on Lp(a) in Subjects With Elevated Lp(a)

Elevated Lp(a)

Denmark
National Institute of Allergy and Infectious Diseases...

Completed

H5 Vaccine Alone or With Aluminum Hydroxide in Elderly Adults

Influenza

United States
National Institute of Allergy and Infectious Diseases...

Completed

Higher Dose Intradermal H5 Vaccine

Influenza

United States
Blood Donation Service Zurich, SRC

Unknown

Whole Genome Sequencing for Blood Group Genotyping and Definition as Exemplified on U- and St(a)+. (Blood Genome)

Genetic Blood Group (bg) Polymorphism in U Negativity and St(a) of MNSs

Switzerland
Institute of Nutrition of Central America and Panama
Bill and Melinda Gates Foundation; Newcastle University; International Atomic...

Completed

Estimation of Vitamin A Stores in Children and Women in Guatemala and Relation With Potential Toxicity Markers (GloVitAS-GU)

Vitamin A Status

Guatemala
Prince of Songkla University

Unknown

Efficacy of Vitamin A Fortified Rice in Lactating Thai Women (EVAL)

Vitamin A Status

Thailand
Medical University of Vienna

Completed

Comparison of IgA Levels in the Bronchoalveolar Lavage Fluid of Patients With and Without Antibiotic Therapy

Immunoglobulin A

Austria
University of California, Davis
Helen Keller International

Completed

Effect of Small Daily Doses of B-carotene on Breast Milk Retinol

Vitamin A Status

United States
Tufts University
Nutricia Research Fundation; National University of Science and Technology,...

Completed

Bioavailability of Yellow Maize Carotenoids in Humans

Vitamin A Status

Zimbabwe

Search clinical trials for: Hyperlipoproteinemia(a)

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