Search clinical trials for: Immunological profile

Total 16023 results

Azienda Ospedaliera Specializzata in Gastroenterologia...
Cozzolongo Raffaele; Shahini Endrit; Notarnicola Maria; De Pergola Giovanni; Lippolis...

Not yet recruiting

Changes in the Lipidomic, Immunological and miRNA Profile in Patients Undergoing a Dietary Program or Bariatric Surgery

Obesity | Liver Disease Parenchymal

Italy
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

HCQ+ADC vs ADC in the Treatment of Advanced Breast Cancer

Advanced Breast Cancer | Metastatic Breast Cancer

China
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Study of the Blood and Skin Immunological Profile of Patients With Recessive Dystrophic Epidermolysis Bullosa: in Vivo Analysis and the Impact of Placental Stem Cells in Vitro (ISTRADEB)

Epidermolysis Bullosa Dystrophica
Mabscale, LLC

Recruiting

Study, Evaluating Pharmacokinetics, Pharmacodynamics, Immunogenicity and Safety Profiles of Rituximab Compared to MabThera® in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis

Russian Federation
Peter MacCallum Cancer Centre, Australia
Sanofi; Regeneron Pharmaceuticals; Monash University; University of Adelaide; University...

Recruiting

Deep sequencIng in Cutaneous Squamous CEll caRciNomas (DISCERN)

Neoplasms | Cutaneous Squamous Cell Carcinoma of the Head and Neck | Non-melanoma Skin Cancer | Cutaneous Squamous Cell Carcinoma

Australia
Nazarbayev University
Ministry of Education and Science, Republic of Kazakhstan

Not yet recruiting

Immunological Profile and Microbial Markers in Evaluating the Effectiveness of Probiotic Therapy in RA Patients

Rheumatoid Arthritis
Hackensack Meridian Health
MedSIR

Recruiting

Immune Profile Selection By Fraction of ctDNA in Patients With Advanced NSCLC Treated With Immunotherapy (G360-IIT)

Carcinoma, Non-Small-Cell Lung

United States
Leiden University Medical Center

Recruiting

89Zr-Bevacizumab PET/CT Imaging in NF2 Patients

Neurofibromatosis 2

Netherlands
Centre Hospitalier Universitaire, Amiens

Recruiting

Immune Profile Analysis and Biomarker Identification in Women With Repeated Implantation Failure or Unexplained Recurrent Spontaneous Miscarriage (ERIM)

Recurrent Miscarriage | Immune System | Repeated Embryo Implantation Failure

France
Arcus Biosciences, Inc.
Gilead Sciences

Recruiting

A Clinical Trial of a New Combination Treatment, Domvanalimab and Zimberelimab, Plus Chemotherapy, for People With an Upper Gastrointestinal Tract Cancer That Cannot be Removed With Surgery That Has Spread to Other Parts of the Body (STAR-221)

Advanced Upper Gastrointestinal Tract Adenocarcinoma

United States, France, Spain, Korea, Republic of, Hungary, Israel, United Kingdom, Italy, Japan, China, Australia, Canada, Portugal, Romania, Hong Kong, Malaysia, Argentina, Georgia, Serbia, Lithuania, Mexico, Chile, Greece, Guatemala, ... and more
Assiut University

Not yet recruiting

Immunological Profile and Clinical Characteristics of Children Diagnosed With Chronic Granulomatous Disease

CGD
National Cancer Centre, Singapore
National University Hospital, Singapore; Singapore General Hospital; Tan Tock... and other collaborators

Recruiting

Deep, Multi-omics Phenotyping to Predict Response, Resistance and Recurrence to Adjuvant Atezolizumab Plus Bevacizumab in Resected Hepatocellular Carcinoma (EMPHASIS)

Hepatocellular Carcinoma

Singapore
Hospital das Clínicas de Ribeirão Preto
Bristol-Myers Squibb; Fundação de Amparo à Pesquisa do Estado de São Paulo

Recruiting

CLARA: Somatic and Germline Mechanisms That Impact Renal Cancer Immunotherapy

Renal Cancer Metastatic

Brazil
Cambridge University Hospitals NHS Foundation Trust
National Institute for Health Research, United Kingdom

Not yet recruiting

Pembrolizumab With Olaparib as Combined Therapy in Metastatic Pancreatic Cancer

Pancreatic Cancer
University Health Network, Toronto
GlaxoSmithKline

Recruiting

Using Genetic Profile to Determine the Treatment for Patients With Ovarian Cancer Who Previously Received a PARP-inhibitor

Ovarian Cancer | Fallopian Tube Cancer | Primary Peritoneal Cancer | High Grade Serous Cancer | High Grade Endometrioid Cancer

Canada
Institut Paoli-Calmettes

Not yet recruiting

Immunological Profile for Patients Treated With CAR-T Cells (SI-CART)

Hematologic Neoplasms

France
Brian Hill

Recruiting

Loncastuximab Tesirine and Venetoclax for Relapsed/ Refractory Non-Hodgkin Lymphoma

Refractory Non-Hodgkin Lymphoma | Relapsed Non Hodgkin Lymphoma

United States
Gustave Roussy, Cancer Campus, Grand Paris

Recruiting

Gustave Roussy Cancer Profiling (STING)

Solid Tumor, Unspecified, Adult

France
Nanobiotix

Recruiting

NBTXR3 With or Without Cetuximab in LA-HNSCC

Aged | Locally Advanced Head and Neck Squamous Cell Carcinoma

France, Spain, Israel, United States, Taiwan, Finland, Japan, Belgium, Korea, Republic of, Hungary, China, Georgia, Portugal, Austria, Bulgaria, Canada, Czechia, Germany, Greece, Romania, Serbia
Emory University
National Cancer Institute (NCI); Novartis; Secura Bio, Inc.

Recruiting

Duvelisib Exposure to Enhance Immune Profiles of T Cells in Patients With Recurrent or Refractory Diffuse Large B-Cell Lymphoma, DEEP T CELLS Study

Recurrent Diffuse Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma

United States
Centre Leon Berard

Recruiting

Efficacy of the Combination of Nivolumab and Ipilimumab as a Treatment in Patients With Sarcoma of Rare Subtype (RAR-Immune)

Sarcoma

France
Daiichi Sankyo
Merck Sharp & Dohme LLC; AstraZeneca

Recruiting

HER3-DXd (Patritumab Deruxtecan; U3-1402) in Combination With Osimertinib in Subjects With Locally Advanced or Metastatic EGFR-mutated Non-Small Cell Lung Cancer

Non-Small Cell Lung Cancer (NSCLC)

United States, Korea, Republic of, Taiwan, Japan
Oncodesign SA

Recruiting

OncoSNIPE - Study of Molecular Profiles Associated With the Development of Resistance in Solid Cancer Patients (OncoSNIPE)

CANCER

France
University Hospital Southampton NHS Foundation...
AstraZeneca

Recruiting

Acalabrutinib in Combination With R-CHOP for Previously Untreated Diffuse Large B-cell Lymphoma (DLBCL) (REMoDL-A)

Diffuse Large B Cell Lymphoma

United Kingdom
Duke University
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS) (POPS or POP02)

Heart Failure | Pain | Pneumonia | Hypertension | Edema | Hemophilia | Insomnia | Pulmonary Arterial Hypertension | Coagulation Disorder | Asthma in Children | Down Syndrome | Attention Deficit Hyperactivity Disorder | Bronchopulmonary Dysplasia | Hypokalemia | Hyperphosphatemia | Primary Hyperaldosteronism | Adrenal Insufficiency and other conditions

United States, Canada
Centre Oscar Lambret
Institut National de la Santé Et de la Recherche Médicale, France

Recruiting

Phenotypic Characterization Tumor-infiltrating Lymphocytes at Diagnosis and After Chemotherapy in Ovarian Cancer (TILsOV-1805)

Ovarian Cancer Stage IIIC | Ovarian Cancer Stage IV | Fallopian Tube Cancer Stage IIIC | Fallopian Tube Cancer Stage IV

France
University of Roma La Sapienza
University of Palermo; Federico II University; University of Padova; University... and other collaborators

Recruiting

The Circadian Rhythm in CusHing SyndrOme in Active Phase and dUring RemiSsion (TheHOURS) (TheHOURS)

Cushing Syndrome

Italy
The Netherlands Cancer Institute
Bristol-Myers Squibb; Eli Lilly and Company; Bayer; GlaxoSmithKline; Merck Sharp... and other collaborators

Recruiting

The Drug Rediscovery Protocol (DRUP Trial) (DRUP)

Cancer | Neoplasm | Tumors | Neoplasia

Netherlands
Neuromed IRCCS

Recruiting

Immunological Profile in Relation to Cardiac Geometry in Hypertension

Immune System Profile During Hypertensive Cardiac Remodeling

Italy
Longevity Biotech
Michael J. Fox Foundation for Parkinson's Research; Corporal Michael J. Crescenz...

Terminated

Parkinson's Disease Inflammatory Biomarker Profiling

Parkinson Disease

United States
Singapore National Eye Centre
SingHealth Translational Immunology and Inflammation Centre; TTSH Eye Clinic

Completed

Exploring Immune Cell Signatures in Autoimmunity and Dry Eye Syndrome

Dry Eye Syndrome | Autoimmunity

Singapore
Singapore National Eye Centre
Singapore General Hospital

Completed

Ocular Surface Disease in Chronic Graft-Versus-Host Disease (GVHD) Patients

Dry Eye | GVHD

Singapore
Rahul Aggarwal
Xynomic Pharmaceuticals, Inc.

Completed

Abexinostat in Combination With Pembrolizumab in Patients With Advanced Solid Tumor Malignancies

Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Metastatic Melanoma | Stage III Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Stage IIIA Lung Cancer AJCC v8 | Stage IIIB Lung Cancer AJCC v8 | Locally Advanced Melanoma | Metastatic Malignant Solid Neoplasm | Metastatic Urothelial... and other conditions

United States
Jonsson Comprehensive Cancer Center
Genentech, Inc.

Completed

Bevacizumab and Temozolomide in Treating Older Patients With Newly-Diagnosed Glioblastoma Multiforme or Gliosarcoma

Glioblastoma | Gliosarcoma | Giant Cell Glioblastoma

United States
Mabscale, LLC

Active, not recruiting

Study, Evaluating Pharmacokinetics, Immunogenicity and Safety Profiles of Pertuzumab Compared to Perjeta® in Healthy Man

Healthy Men

Russian Federation
UNICANCER
AstraZeneca; Intergroupe Francophone de Cancerologie Thoracique; Fondation ARC

Completed

SAFIR02_Lung - Efficacy of Targeted Drugs Guided by Genomic Profiles in Metastatic NSCLC Patients (SAFIR02_Lung)

Non-small Cell Lung Cancer Metastatic

France
University of Nebraska
National Cancer Institute (NCI); Genta Incorporated

Terminated

Oblimersen Sodium & Combination Chemotherapy in Treating Patients With Newly Diagnosed Diffuse Large B-Cell Lymphoma

Stage III Adult Diffuse Large Cell Lymphoma | Stage IV Adult Diffuse Large Cell Lymphoma | Contiguous Stage II Adult Diffuse Large Cell Lymphoma | Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma | Stage I Adult Diffuse Large Cell Lymphoma

United States
Arcus Biosciences, Inc.

Completed

A Study to Investigate the Pharmacokinetic Profile of Oral AB680 in Healthy Volunteers

Healthy Volunteers

Australia
St. Jude Children's Research Hospital
Pfizer; Gateway for Cancer Research

Completed

A Phase II Trial of Avelumab in Patients With Recurrent or Progressive Osteosarcoma

Osteosarcoma

United States
National Cancer Institute (NCI)

Completed

Nivolumab (Anti-PD1), Tadalafil and Oral Vancomycin in People With Refractory Primary Hepatocellular Carcinoma or Liver Dominant Metastatic Cancer From Colorectal or Pancreatic Cancers

Metastatic Colorectal Cancer | Hepatocellular Carcinoma | Hepatocellular Cancer | Metastatic Pancreatic Cancer | Liver Metastasis

United States
Samara State Medical University

Enrolling by invitation

Clinical and Metabolic, Immunological and Microbiological Characteristics of Obese Patients

Obesity

Russian Federation
Centre Hospitalier Universitaire de Nīmes
Institute of Human Genetics, Montpellier

Active, not recruiting

Immunological Profiling of Patients With COVID-19 in Respiratory Distress (ACTICOV-2)

Covid-19 | SARS-CoV-2

France
Sumitomo Pharma Oncology, Inc.
Syneos Health

Completed

A Study of DSP-0509 in Patients With Advanced Solid Tumors to Determine the Safety and the Pharmacokinetic Profile

Neoplasms

United States
CareDx

Withdrawn

KidneyCare Immuno-optimization in Renal Allografts (KIRA)

Immunosuppression | Kidney Transplant | Allograft
National Allergy Research Center, Denmark
University of Copenhagen

Completed

The Immunological Profile of Nickel Dermatitis

Allergy | Inflammatory Response | Nickel Sensitivity | Nickel; Eczema

Denmark
University Hospital, Montpellier

Completed

Characterization of the Immunological Profile Patients With Post-polio Syndrome

Poliomyelitis Sequelae

France
Hospices Civils de Lyon

Withdrawn

Identification by Cytometry by Mass of Predictive Immunological Profiles of Answer to Treatmentby Biotherapics for Patients With Crohn's Disease (PICTURE)

Crohn Disease
Indiana University

Completed

Immunological Profile Changes In Patients With Advanced Non-Small Cell Lung Cancer

Healthy | Non Small Cell Lung Cancer | Non Small Cell Lung Cancer Metastatic

United States
Istituto Scientifico Romagnolo per lo Studio e...

Unknown

Exploring Disease Immunogenicity and the Immunological Effects of Hypomethylating Agents in Acute Myeloid Leukemia (Immune-AML)

Acute Myeloid Leukemia

Italy
Taipei Medical University WanFang Hospital

Completed

Immune Profile and Prognosis of Malignant Liver Tumors With Radiofrequency Ablation (RFA) Therapy (RFA)

Liver Cancer

Taiwan

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