Search clinical trials for: Instantaneous wave Free Ratio

Total 10650 results

Yonsei University
Philips Healthcare

Recruiting

Impact of Dynamic CoROnary RoADmap System for Guidance of Instantaneous Wave-Free Ratio or Fractional Flow Reserve (ROAD-IFR)

Ischemic Heart Disease

Korea, Republic of
Daugavpils Regional Hospital
Riga Stradins University

Recruiting

Instantaneous Wave-free Ratio Guidance Strategy Evaluation in the Treatment of Multivessel Acute Coronary Syndrome. (iStrategy)

Acute Coronary Syndrome | Cardiac Ischemia

Latvia
Amsterdam UMC, location VUmc

Recruiting

Registry of Patients That Have Undergone ICA or PCI (ICA-PI)

Coronary Artery Disease

Netherlands
Prakash Punjabi

Recruiting

iFR Guided Coronary Artery Bypass Grafting Surgery (iCABG)

Coronary Artery Disease | Coronary Stenosis | Ischaemic Heart Disease

United Kingdom
Yale University

Enrolling by invitation

Fractional Flow Reserve and Instantaneous Free-wave Ratio Revascularization Strategies in Women (FiRST)

Coronary Disease | Percutaneous Coronary Intervention | Cardiac Catheterization | Myocardial Perfusion Imaging | Exercise Test

United States
Maimónides Biomedical Research Institute of Córdoba

Active, not recruiting

Usefulness of the Use of Co-registration Strategy With iFR in Long and/or Diffuse Coronary Lesions (iLARDI)

Instantaneous Wave Free Ratio | Diffuse Coronary Artery Disease | Long Coronary Lesion | Syncvision Software

Spain
Samsung Medical Center
Seoul National University Hospital; Philips Healthcare

Active, not recruiting

INsTantenous wavE-Free Ratio-guided PCI Versus Fractional Flow REserve-Guided PCI in rouTine Clinical Practice, Prospective, Multicenter Registry (INTERPRET)

Stable Angina | ST-segment Elevation Myocardial Infarction | Unstable Angina | Non ST Segment Elevation Myocardial Infarction | Silent Myocardial Ischemia

Korea, Republic of
ECRI bv
Boston Scientific Corporation; Volcano Corporation

Completed

Trial Evaluating New Strategy in the Functional Assessment of 3-vessel Disease Using SYNTAXII Score in Patients With PCI

Heart Diseases | Cardiovascular Diseases | 3 Vessel Coronary Artery Disease

Netherlands, Poland, Spain, United Kingdom
Aga Khan University Hospital, Pakistan

Completed

Clinical Outcomes of Patients With Deferred Revascularization Based on FFR and iFR Negative Coronary Artery Lesions.

Coronary Artery Disease

Pakistan
Mid and South Essex NHS Foundation Trust

Completed

The Physiological Impact of CTO PCI on Coronary Pressure Measurements and Correlation in Donor Vessel (IMPACT-CTO)

Coronary Artery Disease | Acute Coronary Syndrome

United Kingdom
East Carolina University
Imperial College London; Volcano Corporation

Completed

Correlation Study of Imaging Data Acquired During CABG With Data Acquired in the Cath Lab (PERSEUS)

Coronary Artery Disease

United States
Azienda Ospedaliera Città della Salute e della...
Politecnico di Torino

Unknown

Relationship Between Fractional Flow Reserve/ Instantaneous Wave Free Ratio and Endothelial Wall Shear Stress (RELATE)

Coronary Artery Disease | Acute Coronary Syndrome | Stable Angina

Italy
Seoul National University Hospital
Samsung Medical Center

Unknown

Association Between IVUS and OCT Parameters and Invasive Physiologic Indices

Ischemic Heart Disease

Korea, Republic of
Volcano Corporation

Terminated

User Evaluation Study of SyncVision System With Software v4.X (Prepare II)

Coronary Artery Disease

Israel
General University Hospital, Prague
University of Iowa

Unknown

FFR Versus iFR in Assessment of Hemodynamic Lesion Significance (FiGARO)

Hemodynamics | Tomography, Optical Coherence | Coronary Circulation | Endothelial Cells | Polymorphism, Genetic

Czech Republic
Uppsala University

Completed

Evaluation of iFR vs FFR in Stable Angina or Acute Coronary Syndrome (iFR Swedeheart)

Angina Pectoris | Acute Myocardial Infarction

Sweden, Denmark, Iceland
Azienda Ospedaliera San Camillo Forlanini

Unknown

Instantaneous Wave-Free Ratio and Fractional Flow Reserve for the Assessment of Non Culprit Lesions in Patients With ST-segment Elevation Myocardial Infarction (WAVE)

ST Segment Elevation Myocardial Infarction

Italy
Volcano Corporation

Completed

The REAL Registry for Utilization of iFR in Assessing Coronary Stenoses (DEFINE REAL)

Coronary Disease

Belgium
Shanghai 10th People's Hospital

Unknown

Determination of Instantaneous Wave-Free Ratio by Computed Tomography (iFRCT)

Coronary Artery Disease

China
National University of Ireland, Galway, Ireland

Recruiting

Multivessel TALENT

Myocardial Ischemia | Heart Diseases | Cardiovascular Diseases | Vascular Diseases | Coronary Artery Disease | Coronary Disease | Arterial Occlusive Diseases

Ireland
American Heart of Poland
Silesian Centre for Heart Diseases; Andrzej Frycz Modrzewski Kraków University... and other collaborators

Not yet recruiting

Revascularization Strategies in Patients With Non-ST-Segment Elevation Acute Coronary Syndrome (NSTE-ACS) and Severe Coronary Artery Disease (MILESTONE)

Acute Coronary Syndrome | Multivessel Coronary Artery Disease

Poland
Imperial College London
Hospital San Carlos, Madrid

Completed

Vasodilator Free Measure of Fractional Flow Reserve (ADVISE)

Coronary Stenosis

United Kingdom
NHS National Waiting Times Centre Board
Stanford University; Catharina Ziekenhuis Eindhoven; Onze Lieve Vrouw Hospital; Brno University Hospital and other collaborators

Completed

Fractional Flow Reserve (FFR) Versus Instant Wave-Free Ratio (iFR)

Coronary Artery Disease | Plaque, Atherosclerotic

Netherlands, United States, Czech Republic, Belgium, Sweden
Merck Sharp & Dohme LLC

Recruiting

Study of MK-6552 in Participants With Narcolepsy Type 1 (MK-6552-004)

Narcolepsy

United States
University of Sharjah

Recruiting

Assessment of the Effect of Non-surgical Periodontal Treatment on Endothelial Function- a Prospective Study

Periodontal Diseases | Endothelial Dysfunction

United Arab Emirates
Murdoch Childrens Research Institute
National Health and Medical Research Council, Australia; Royal Children's Hospital and other collaborators

Recruiting

Generation Victoria Cohort 2020s: A Statewide Longitudinal Cohort Study of Victorian Children and Their Parents (GenV)

Communicable Diseases | Quality of Life | Inflammation | Obesity | Congenital Abnormalities | Genetics | Healthy Aging | Child Development | Diet | Mental Health | Disability | Injuries | Cognition | Child Health | Environmental Exposure | Noncommunicable Diseases | Physical Fitness | Intergenerational Relations | Social Determinants... and other conditions

Australia
Daiichi Sankyo
Merck Sharp & Dohme LLC; AstraZeneca

Recruiting

Study of Dato-DXd Plus Pembrolizumab vs Pembrolizumab Alone in the First-line Treatment of Subjects With Advanced or Metastatic NSCLC Without Actionable Genomic Alterations (TROPION-Lung08)

Metastatic Non Small Cell Lung Cancer

United States, China, Belgium, Portugal, Japan, Taiwan, France, United Kingdom, Spain, Hungary, Thailand, Germany, Italy, Switzerland, Hong Kong, Korea, Republic of, Australia, Mexico, Brazil, Netherlands, Romania, Argentina, Chile, G... and more
Royal Free Hospital NHS Foundation Trust
Private Physiotherapy Education Fund

Recruiting

Can Waveform and Flow Traces From Mechanical Insuflattion:Exsufflation (MI:E) be Used to Identify Laryngeal Responses to MI:E and Thus Optimise Treatment Algorithms? (SETTLE)

Neuromuscular Diseases

United Kingdom
Merck Sharp & Dohme LLC

Recruiting

A Study of Zilovertamab Vedotin (MK-2140) in Combination With Standard of Care in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (rrDLBCL) (MK-2140-003)

Diffuse Large B-Cell Lymphoma | DLBCL

Poland, United States, France, Israel, Italy, Turkey, Canada, Korea, Republic of, United Kingdom, Thailand, China
Xiuli Zuo

Not yet recruiting

Efficacy and Safety of 14-day Concomitant Therapy for Difficult-to-Treat Helicobacter Pylori Infection

Helicobacter Pylori Infection

China
National University of Ireland, Galway, Ireland

Recruiting

The PIONEER-IV Study is Comparing Clinical Outcomes Between Angiography-derived Physiology Guidance to Usual Care in an All-comers PCI Population With Unrestrictive Use of the HT Supreme Sirolimus-eluting Stent (PIONEER-IV)

Coronary Artery Disease

Belgium, Netherlands, Ireland, United Kingdom, Spain
Tampere University Hospital

Recruiting

Small Airway Inflammation and Dysfunction in Different Asthma Phenotypes

Asthma

Finland
University of Manitoba

Recruiting

Spinal Anesthesia For Enhanced Recovery After Liver Surgery (SAFER-L)

Pain, Postoperative | Liver Neoplasms | Hepatectomy

Canada
Merck Sharp & Dohme LLC

Recruiting

Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)

Solid Tumors | Hematologic Malignancies

United States, Poland, Brazil, Ukraine, Argentina, Australia, Austria, Belgium, Canada, Chile, China, Colombia, Czechia, Denmark, Estonia, Finland, France, Germany, Greece, Guatemala, Hong Kong, Hungary, Israel, Italy, Japan, Korea, Republic... and more
Vertos Medical, Inc.

Recruiting

MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study

Lumbar Spinal Stenosis

United States
NRG Oncology
National Cancer Institute (NCI)

Recruiting

Doxorubicin Hydrochloride and Cyclophosphamide Followed by Paclitaxel With or Without Carboplatin in Treating Patients With Triple-Negative Breast Cancer

Stage IIIA Breast Cancer | Stage IB Breast Cancer | Stage IIA Breast Cancer | Stage IIB Breast Cancer | Stage IIIC Breast Cancer | Estrogen Receptor Negative | HER2/Neu Negative | Progesterone Receptor Negative | Triple-Negative Breast Carcinoma | Breast Adenocarcinoma

United States, Canada
Boston Scientific Corporation

Active, not recruiting

Paresthesia-Free Fast-Acting Subperception (FAST) Study (FAST)

Chronic Pain

United States
National Cancer Institute (NCI)

Active, not recruiting

Oxaliplatin, Leucovorin Calcium, and Fluorouracil With or Without Bevacizumab in Treating Patients Who Have Undergone Surgery for Stage II Colon Cancer

Lynch Syndrome | Colon Mucinous Adenocarcinoma | Colon Signet Ring Cell Adenocarcinoma | Stage IIA Colon Cancer AJCC v7 | Stage IIB Colon Cancer AJCC v7 | Stage IIC Colon Cancer AJCC v7

United States, Canada, Puerto Rico, Peru, South Africa
National Cancer Institute (NCI)

Active, not recruiting

Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)

Glioma | Hematopoietic and Lymphoid Cell Neoplasm | Melanoma | Lymphoma | Multiple Myeloma | Recurrent Ovarian Carcinoma | Breast Carcinoma | Recurrent Head and Neck Carcinoma | Recurrent Lung Carcinoma | Recurrent Skin Carcinoma | Gastric Carcinoma | Advanced Lymphoma | Advanced Malignant Solid Neoplasm | Refractory... and other conditions

United States, Puerto Rico, Guam
National Cancer Institute (NCI)

Active, not recruiting

Testing the Timing of Pembrolizumab Alone or With Chemotherapy as First Line Treatment and Maintenance in Non-small Cell Lung Cancer

Stage IV Lung Cancer AJCC v8 | Lung Non-Squamous Non-Small Cell Carcinoma | Stage IIIB Lung Cancer AJCC v8 | Stage IIIC Lung Cancer AJCC v8

United States, Canada, Guam
National Cancer Institute (NCI)

Active, not recruiting

Testing the Addition of an Antibody to Standard Chemoradiation Followed by the Antibody for One Year to Standard Chemoradiation Followed by One Year of the Antibody in Patients With Unresectable Stage III Non-Small Cell Lung Cancer

Stage III Lung Cancer AJCC v8 | Stage IIIA Lung Cancer AJCC v8 | Stage IIIB Lung Cancer AJCC v8 | Stage IIIC Lung Cancer AJCC v8 | Unresectable Lung Non-Small Cell Carcinoma | Recurrent Lung Non-Small Cell Carcinoma

United States, Guam
National Cancer Institute (NCI)
NCIC Clinical Trials Group; Cancer and Leukemia Group B; North Central Cancer... and other collaborators

Active, not recruiting

Chemotherapy With or Without Bevacizumab in Treating Patients With Stage IB, Stage II, or Stage IIIA Non-small Cell Lung Cancer That Was Removed By Surgery

Stage IB Lung Non-Small Cell Carcinoma AJCC v7 | Stage IIA Lung Non-Small Cell Carcinoma AJCC v7 | Stage IIB Lung Non-Small Cell Carcinoma AJCC v7 | Stage IIIA Lung Non-Small Cell Cancer AJCC v7

United States, Canada, Ireland, Peru, South Africa
Merck Sharp & Dohme LLC

Active, not recruiting

A Study of Pembrolizumab (MK-3475) With or Without Maintenance Olaparib in First-line Metastatic Squamous Non-small Cell Lung Cancer (NSCLC, MK-7339-008/KEYLYNK-008)

Carcinoma, Squamous Cell, Non-small-cell Lung

Poland, Korea, Republic of, United States, Argentina, Australia, Austria, Brazil, Canada, France, Germany, Japan, Mexico, New Zealand, Romania, Russian Federation, Spain, Taiwan, Turkey, Ukraine, United Kingdom
National Cancer Institute (NCI)

Active, not recruiting

Testing The Addition of a New Anti-cancer Drug, Venetoclax, to the Usual Treatment (Ibrutinib and Obinutuzumab) in Untreated, Older Patients With Chronic Lymphocytic Leukemia

Chronic Lymphocytic Leukemia | Small Lymphocytic Lymphoma

United States
National Cancer Institute (NCI)
NCIC Clinical Trials Group; Cancer and Leukemia Group B; North Central Cancer... and other collaborators

Active, not recruiting

Hormone Therapy With or Without Combination Chemotherapy in Treating Women Who Have Undergone Surgery for Node-Negative Breast Cancer (The TAILORx Trial) (TAILORx)

Hormone Receptor Positive | Stage IA Breast Cancer AJCC v7 | Stage IB Breast Cancer AJCC v7 | Stage IIA Breast Cancer AJCC v6 and v7 | Stage IIB Breast Cancer AJCC v6 and v7 | Stage IIIB Breast Cancer AJCC v7 | Breast Adenocarcinoma

United States, Canada, Australia, Puerto Rico, New Zealand, Ireland, Peru, United Kingdom
National Cancer Institute (NCI)
Eastern Cooperative Oncology Group; Cancer and Leukemia Group B; North Central...

Active, not recruiting

Doxorubicin Hydrochloride, Cyclophosphamide, and Paclitaxel With or Without Bevacizumab in Treating Patients With Lymph Node-Positive or High-Risk, Lymph Node-Negative Breast Cancer

Breast Adenocarcinoma

United States, Peru, South Africa
National Cancer Institute (NCI)
NRG Oncology

Active, not recruiting

Testing the Drug Atezolizumab or Placebo With Usual Therapy in First-Line HER2-Positive Metastatic Breast Cancer

Unresectable Breast Carcinoma | Stage IV Breast Cancer AJCC v6 and v7 | Stage III Breast Cancer AJCC v7 | Metastatic Breast Adenocarcinoma | Metastatic HER2-Positive Breast Carcinoma | Recurrent Breast Adenocarcinoma | Recurrent HER2-Positive Breast Carcinoma | Unresectable HER2-Positive Breast Carcinoma

United States, Canada
National Cancer Institute (NCI)

Active, not recruiting

Tamoxifen Citrate or Z-Endoxifen Hydrochloride in Treating Patients With Locally Advanced or Metastatic, Estrogen Receptor-Positive, HER2-Negative Breast Cancer

Recurrent Breast Carcinoma | Stage IV Breast Cancer AJCC v6 and v7 | Stage III Breast Cancer AJCC v7 | Stage IIIA Breast Cancer AJCC v7 | Stage IIIB Breast Cancer AJCC v7 | Stage IIIC Breast Cancer AJCC v7

United States
National Cancer Institute (NCI)
NRG Oncology

Active, not recruiting

Targeted Treatment for ALK Positive Patients Who Have Previously Been Treated for Non-squamous Non-small Cell Lung Cancer

Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Lung Non-Squamous Non-Small Cell Carcinoma

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing Maintenance Therapy for Small Cell Lung Cancer in Patients With SLFN11 Positive Biomarker

Extensive Stage Lung Small Cell Carcinoma

United States

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