Search clinical trials for: LAG-3

Total 18057 results

Shanghai Henlius Biotech

Completed

Evaluate the Safety, Tolerability, Pharmacokinetic Characteristics and Preliminary Efficacy of HLX26 and HLX10 in Patients With Advanced/Metastatic Solid Tumor

Adult Solid Tumor

China
Shanghai Henlius Biotech

Completed

A Clinical Study to Evaluate the Safety, Tolerability and Pharmacokinetic Characteristics of HLX26 Monoclonal Antibody Injection in Patients With Solid Tumor or Lymphoma

Lymphoma | Solid Tumor, Adult

China
Immutep S.A.S.
Umanis

Completed

IMP321 Phase 1 Trial in Metastatic Renal Cell Carcinoma (MRCC)

Stage IV Renal Cell Carcinoma

France
Symphogen A/S

Completed

Sym022 (Anti-LAG-3) in Patients With Advanced Solid Tumor Malignancies or Lymphomas

Lymphoma | Solid Tumor | Metastatic Cancer

Canada, United States
Zhongnan Hospital

Recruiting

Clinical Study for Combined Analysis of CTC and Exosomes on Predicting the Efficacy of Immunotherapy in Patients With Hepatocellular Carcinoma

Hepatocellular Carcinoma

China
Immutep S.A.S.
SGS Aster-Cephac (CRO)

Completed

Phase I Study of IMP321 Given Alone or as an Adjuvant to a Reference Flu Antigen

Healthy

France
Immutep S.A.S.
Umanis

Completed

IMP321 Plus First-line Paclitaxel in Metastatic Breast Carcinoma

Metastatic Breast Cancer

France
Symphogen A/S

Completed

Sym021 Monotherapy, in Combination With Sym022 or Sym023, and in Combination With Both Sym022 and Sym023 in Patients With Advanced Solid Tumor Malignancies or Lymphomas

Lymphoma | Solid Tumor | Metastatic Cancer

Canada, United States
The First Affiliated Hospital of Xiamen University

Recruiting

PET Imaging of LAG-3 Expression

Tumor, Solid

China
Instituto Traumatologico Dr. Teodoro Gebauer Weisser

Unknown

Comparison of Dynamic Versus Static Lag Screw Modes for Cephalomedullary Nails Used to Fix Intertrochanteric Fragility Fractures

Hip Fractures

Chile
Washington University School of Medicine

Terminated

Lag-3 and Gemcitabine for Treatment of Advanced Pancreas Cancer

Pancreatic Neoplasms

United States
Aswan University Hospital

Recruiting

Iron, Alpha-Synuclein, and Lymphocyte-activation Gene-3 in Ischemic Stroke

Brain Ischemia

Egypt
Samsung Medical Center

Recruiting

LAG3 Expression in Triple Negative Breast Cancer

Triple Negative Breast Cancer | Immune Checkpoint Inhibitor

Korea, Republic of
University of Alabama at Birmingham

Not yet recruiting

PD-1, LAG-3 and TIM-3 Checkpoint Blockade in DLBCL

Lymphoma, Follicular | Lymphoma, B-Cell | Diffuse Large B Cell Lymphoma

United States
Riphah International University

Completed

DAPRE Exercises Technique and CKC Exercises on Extensor Lag in Post Knee Stiffness

Extensor Lag | Post-operative Knee Stiffness

Pakistan
Peking University Third Hospital

Not yet recruiting

Correlation Between Preoperative Knee Extension Lag and Functional Outcome After Total Knee Arthroplasty

Total Knee Arthroplasty | Extension Lag
Tesaro, Inc.
GlaxoSmithKline

Completed

Study of TSR-033 With an Anti-programmed Cell Death-1 Receptor (PD-1) in Participants With Advanced Solid Tumors (CITRINO)

Neoplasms

United States, France
Immutep S.A.S.
SGS Aster-Cephac (CRO)

Completed

A Randomized Phase I Study of a Hepatitis B Antigen Combined With IMP321

Healthy

France
NorthShore University HealthSystem
Chiesi USA, Inc.

Recruiting

Prophylactic Minimally Invasive Surfactant Evaluation (PreProMISe)

Premature Birth | Respiratory Distress Syndrome, Newborn

United States
Vanda Pharmaceuticals

Completed

A Proof of Concept Study to Evaluate the Effects of Tasimelteon and Placebo in Travelers With Jet Lag Disorder

Jet Lag Disorder

United States
University Medical Center Groningen
Regeneron Pharmaceuticals

Active, not recruiting

LAG3 PET Imaging in Advanced Solid Tumors

Metastatic Solid Tumor

Netherlands
Incyte Biosciences International Sàrl

Completed

A Safety and Tolerability Study of INCAGN02385 in Select Advanced Malignancies

Cervical Cancer | Hepatocellular Carcinoma | Esophageal Cancer | Ovarian Cancer | Mesothelioma | Non-small Cell Lung Cancer (NSCLC) | Urothelial Carcinoma | Merkel Cell Carcinoma | Diffuse Large B-cell Lymphoma | Triple-negative Breast Cancer | Renal Cell Carcinoma (RCC) | Small Cell Lung Cancer (SCLC) | Squamous... and other conditions

United States
Multiple Myeloma Research Consortium
Bristol-Myers Squibb; Memorial Sloan Kettering Cancer Center; Washington University... and other collaborators

Active, not recruiting

Immuno-Oncology Drugs Elotuzumab, Anti-LAG-3 and Anti-TIGIT

Multiple Myeloma | Relapsed Refractory Multiple Myeloma

United States
Vanda Pharmaceuticals

Completed

An Observational Study to Investigate the Effects of Rapid Transmeridian Travel

Jet Lag Disorder

United States
Vanda Pharmaceuticals

Completed

Evaluating the Effects of Tasimelteon vs. Placebo on Jet Lag Type Insomnia

Jet Lag Type Insomnia

United States
National Taiwan University Hospital

Recruiting

UVB-induced Treg Cells Exert Antigen-specific Suppression Through LAG-3

Psoriasis | Atopic Dermatitis

Taiwan
Qi-Yong Li

Completed

Single-operator Wire-guided Endoscopic Retrograde Cholangiopancreatography Cannulation Technique

Biliary Diseases | Pancreas Diseases

China
Universidade Federal do Rio de Janeiro

Unknown

Influence of the Number of Layers of a One Bottle Adhesive on the Longevity of Composite Restorations in Primary Molars

Dental Caries | Secondary Dental Caries

Brazil
University of Colorado, Boulder
University of Colorado, Denver

Recruiting

Biomarkers for Peripheral Circadian Clocks in Humans

Circadian Rhythms

United States
Zealand University Hospital
Region Zealand

Completed

Closure of Uterine Incision by Single or Double Layer Technique

Pregnancy

Denmark
Regeneron Pharmaceuticals

Recruiting

Clinical Study of Fianlimab in Combination With Cemiplimab in Adolescent and Adult Patients With Previously Untreated Unresectable Locally Advanced or Metastatic Melanoma

Melanoma

United States, Spain, Germany, Mexico, Turkey, Canada, Austria, Netherlands, United Kingdom, Italy, Georgia, France, Brazil, Romania, Czechia, Argentina, Australia, Ireland, Chile, Hungary, South Africa, Belgium, Poland, Peru
ABL Bio, Inc.

Recruiting

Study to Evaluate the Safety and Tolerability of ABL501, and to Determine the Maximum Tolerated Dose (MTD) and Recommended Phase 2 Dose (RP2D) of ABL501 in Subjects With Any Progressive, Locally Advanced (Unresectable) or Metastatic Solid Tumors

Advanced Solid Tumor

Korea, Republic of
Hams Hamed Abdelrahman

Completed

Herbert Screw vs Lag Screw Fixation in Anterior Mandibular Fracture Treatment

Mandibular Fractures

Egypt
Hospices Civils de Lyon

Completed

Efficacy of Phosphatidylserine Enriched With n-3 PUFA Supplementation on ADHD in Children With Epilepsy (AGPIn3)

Epilepsy | Child | Attention Deficit Disorder With Hyperactivity | ADHD Inattention or Mixed Type

France
Stanford University
McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.

Completed

Indirect Magnetic Resonance Lymphangiography of the Head and Neck Region Using Conventional Gadolinium-based Contrast

Head and Neck Cancer | Head and Neck Cancers

United States
wei bo

Unknown

Comparison of Surgical,Clinical and Oncological Outcomes Between Robotic-assisted and Laparoscopic-assisted Gastrectomy

Gastric Cancer
Ahmed Saad
Hawaa Fertility Center

Completed

Time Lag for Oocyte Denudation: A Better Choice for ICSI Outcome?!

Infertility, Female

Egypt
Centre Hospitalier Universitaire Vaudois
Immutep S.A.S.

Terminated

Immunotherapy of HLA-A2 Positive Stage II-IV Melanoma Patients (LAG-3/IMP321)

Melanoma

Switzerland
Takeda

Completed

Efficacy of Ramelteon on Insomnia Symptoms Associated With Jet Lag in Healthy Adult Volunteers

Circadian Dysregulation

United States
Cairo University

Unknown

Computer Guided Lag Screw Fixation Versus Conventional Lag Screw Fixation in Anterior Mandibular Fractures

Mandible Fracture

Egypt
University of Arizona
University of California, San Diego

Recruiting

Facilitating Adjustment to Simulated Jet Lag

Circadian Rhythm Sleep Disorder, Jet Lag Type

United States
Prisma Health-Upstate
Arthrex, Inc.

Enrolling by invitation

Lateralization After IntraMedullary Nailing of InterTrochanteric Hip Fractures, Clinical and Radiographic Outcomes (LIMIT)

Intertrochanteric Fractures

United States
Rothman Institute Orthopaedics

Enrolling by invitation

Hip DAA Closure Techniques

Total Hip Replacement | Wound Complication

United States
Regeneron Pharmaceuticals

Recruiting

A Trial to Learn How the Combination of Fianlimab With Cemiplimab and Chemotherapy Works Compared With Cemiplimab and Chemotherapy for Treating Adult Patients With Advanced Non-small Cell Lung Cancer

Non-small Cell Lung Cancer

Korea, Republic of, United States, Malaysia, Australia, Georgia, Israel
Incyte Biosciences International Sàrl

Recruiting

Study of Retinfanlimab in Combination With INCAGN02385 and INCAGN02390 as First-Line Treatment in Participants With PD-L1-Positive (CPS ≥ 1) Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck

Head and Neck Cancer

United States, Taiwan, Italy, Korea, Republic of, Spain, France, Portugal, Germany, Poland, Canada, Georgia, Greece, Netherlands, Belgium
National Cancer Institute (NCI)

Recruiting

The Effect of Diet and Exercise on ImmuNotherapy and the Microbiome (EDEN)

Melanoma

United States
invoX Pharma Limited

Active, not recruiting

A Phase 1/2 Study of FS118 in Patients With Advanced Malignancies

Metastatic Cancer | Squamous Cell Carcinoma of Head and Neck | Advanced Cancer

United States, France
Incyte Corporation

Recruiting

Study of INCA32459 a LAG-3 and PD-1 Bispecific Antibody in Participants With Select Advanced Malignancies

Advanced Malignancies

Spain, United States, France, Italy, Belgium
Dan Zandberg
Bristol-Myers Squibb

Active, not recruiting

Personalized Immunotherapy in Patients With Recurrent /Metastatic SCCHN That Have Progressed on Prior Immunotherapy

Squamous Cell Carcinoma of the Head and Neck

United States
Novartis Pharmaceuticals

Completed

Study of Efficacy and Safety of Novel Spartalizumab Combinations in Patients With Previously Treated Unresectable or Metastatic Melanoma (PLATforM)

Melanoma

United States, Italy, United Kingdom, Netherlands, Canada, Germany, Australia, Spain, Switzerland, France

Search clinical trials for: LAG-3

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