Search clinical trials for: Long-acting muscarinic antagonist

Total 33728 results

AstraZeneca
Parexel

Not yet recruiting

A Study to Assess the Lung Exposure Bioequivalence of Budesonide, Glycopyrronium, & Formoterol (BGF) Metered Dose Inhaler (MDI) Hydrofluoroolefin (HFO) With a Spacer (Treatment B), BGF MDI Hydrofluoroalkane (HFA) With a Spacer (Treatment A), as Well as BGF MDI HFO Without a Spacer (Treatment C)

Healthy

Germany
AstraZeneca

Recruiting

A Study to Assess the Pharmacokinetics and Safety of Budesonide, Glycopyrronium, & Formoterol (BGF) Metered Dose Inhaler (MDI) Hydrofluoroolefin (HFO) With a Spacer (Treatment B), BGF MDI Hydrofluoroalkane (HFA) With a Spacer (Treatment A), as Well as BGF MDI HFO Without a Spacer (Treatment C).

Chronic Obstructive Pulmonary Disease

Germany, United Kingdom
Mylan Pharma UK Ltd.

Completed

Revefenacin in Chinese Subjects With Moderate to Very Severe Chronic Obstructive Pulmonary Disease(COPD)

COPD

China
Boehringer Ingelheim

Completed

Safety of Tiotropium + Olodaterol in Chronic Obstructive Pulmonary Disease (COPD) Patients in Taiwan: a Non-interventional Study Based on the Taiwan National Health Insurance (NHI) Data

Pulmonary Disease, Chronic Obstructive

China
Boehringer Ingelheim

Completed

A Study in South Korea Using Medical Records to Look at Different Treatments for Chronic Obstructive Airway Disease (COPD)

Pulmonary Disease, Chronic Obstructive

Korea, Republic of
AstraZeneca
Parexel

Completed

A Single Inhalation Dose Study to Assess Efficacy, Pharmacokinetics (PK), Safety and Tolerability of AZD8871 in Patients With Long-term Lung Diseases.

Chronic Obstructive Pulmonary Disease

Germany, United Kingdom
Boehringer Ingelheim

Completed

Effectiveness of Triple Therapy in COPD

Pulmonary Disease, Chronic Obstructive

United Kingdom
University of Dundee
Almirall Limited

Completed

Evaluation of Long-Acting Muscarinic Antagonists in COPD (MAN04)

Pulmonary Disease, Chronic Obstructive

United Kingdom
GlaxoSmithKline

Completed

28-day Repeat Dose Study of GSK573719

Pulmonary Disease, Chronic Obstructive

United States, Estonia, Germany, Poland
GlaxoSmithKline

Completed

A Cross-Over Study to Evaluate Lung Function Response After Treatment With Umeclidinium (UMEC) 62.5 Micrograms (mcg), Vilanterol (VI) 25 mcg, and Umeclidinium/Vilanterol (UMEC/VI) 62.5/25 mcg Once-Daily in Subjects With Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive

Ukraine, Slovakia
GlaxoSmithKline

Completed

GSK573719 Dose Ranging Study in Chronic Obstructive Pulmonary Disease

Pulmonary Disease, Chronic Obstructive

Germany, United States
GlaxoSmithKline

Completed

A Phase I Pharmacokinetic Study of Fluticasone Furoate /Umeclidinium Bromide/Vilanterol (100/62.5/25 Microgram [mcg]) After Single and Repeat Dose Administration From a Dry Powder Inhaler in Healthy Chinese Subjects

Pulmonary Disease, Chronic Obstructive

China
Novartis Pharmaceuticals

Completed

Long Term Safety Study of NVA237 vs QAB149 in COPD Patients

Chronic Obstructive Pulmonary Disease (COPD)

United States
Soroka University Medical Center
Ben-Gurion University of the Negev

Terminated

"Death Rattle" - A Double Blind, Randomly Controlled, Crossover Trial

Death | Noise

Israel
Hospital San Carlos, Madrid

Recruiting

Efficacy and Safety of Atropine and DIMS Lenses in Controlling Myopia in Children: A Randomized Clinical Trial. (DIMS)

Myopia

Spain
ASST Fatebenefratelli Sacco

Not yet recruiting

A Study to Investigate the Analgesic Efficacy of Ibuprofen Alone and Ibuprofen Plus Hyoscine-n- Butyl Bromide in Reducing Pain of Outpatient Hysteroscopy

Pain
National Taiwan University Hospital

Not yet recruiting

Sugammadex v.s. Neostigmine/Glycopyrrolate

Head and Neck Neoplasms | Chronic Sinusitis | Chronic Otitis Media

Taiwan
Post Graduate Institute of Medical Education and...

Not yet recruiting

A RCT to Compare the Effectiveness of Nebulized Anticholinergics for Cough Suppression During Flexible Bronchoscopy (NAFCOF)

Subjects Undergoing Flexible Bronchoscopy

India
AstraZeneca

Recruiting

Change in Patient-repOrted Outcomes in COPD Patients Newly Initiated on TRIXEO AEROSPHERE in Real worlD (COnCORD)

Chronic Obstructive Pulmonary Disease (COPD)

Romania
Biomedical Advanced Research and Development Authority
Rho Federal Systems Division, Inc.; Allucent

Not yet recruiting

Sublingual Atropine Bioequivalence by Route of Administration (SABER) (SABER)

Atropine Bioequivalence

United States
The Hong Kong Polytechnic University
The University of Hong Kong

Not yet recruiting

Combination Effect of Optical Defocus and Low Dose Atropine in Myopia Control

Myopia

Hong Kong
James J. Peters Veterans Affairs Medical Center

Recruiting

Transdermal Administration by a Novel Wireless Iontophoresis Device

Constipation | Spinal Cord Injuries | Neurogenic Bowel | Fecal Incontinence

United States
Ain Shams University

Recruiting

Gabapentin Versus Trospium Chloride for Prevention of a Catheter-related Bladder Discomfort Inside the ICU

Catheter-related Bladder Discomfort (CRBD)

Egypt
Essilor-Polylite Taiwan Co., Ltd.

Recruiting

Stellest Lenses and Low-concentration Atropine Myopia Control Among Children

Myopia

Taiwan
Kasr El Aini Hospital

Recruiting

Dexmedetomidine Infusion Dose Versus Rapid Bolus Dose Before Tracheal Intubation.

Dexmedetomidine | Intubation Complication

Egypt
China Medical University Hospital

Not yet recruiting

Pharmacological Treatment Targeting Endotypic Traits of Obstructive Sleep Apnea

Obstructive Sleep Apnea of Adult
The Hong Kong Polytechnic University
The University of Hong Kong

Recruiting

Pharmacological and Non-pharmacological Treatment Effects on Children With Different Predicted Myopia Progression Rate

Myopia

Hong Kong
Ain Shams University

Not yet recruiting

Low Dose Atropine Eye Drops in Myopic Egyptian Children (LAMP)

Myopia Progression | Axial Length, Eye | Sclera Thickness

Egypt
McGill University
Université de Montréal

Not yet recruiting

A Study to Assess the Safety, Tolerability, and Pharmacology of Darifenacin in Patients With ALS

Amyotrophic Lateral Sclerosis

Canada
Eurofarma Laboratorios S.A.

Not yet recruiting

Study of Fluticasone/Formoterol/Glycopyrronium for the Treatment Chronic Obstructive Pulmonary Disease (TRIPLAR) (TRIPLAR)

Chronic Obstructive Pulmonary Disease

Brazil
Aarhus University Hospital
University of Aarhus; Central Denmark Region; Vejle Hospital; TrygFonden, Denmark; Aalborg University Hospital and other collaborators

Recruiting

Patient Education and Duloxetine, Alone and in Combination, for Patients With Multisystem Functional Somatic Disorder (EDULOX)

Functional Disorder

Denmark
Matias Vested

Recruiting

Neostigmine/Glyco-pyrrolate 50 Mikrogram/kg or Sugammadex 2 mg/kg for Reversal of Neuromuscular Blockade in Elderly Patients

Neuromuscular Blockade, Residual

Denmark
Lakehead University

Recruiting

Over-the-Counter Antihistamines & Heat Stress

Allergic Rhinitis | Heat Illness | Heat Injury | Sudomotor Sympathetic Dysfunction

Canada
Rhendra Hardy Mohamad Zaini

Recruiting

Effects of Sugammadex and Conventional Reversal on Lung Function in Laparoscopic Abdominal Surgery

Pulmonary Function; Newborn, Abnormal | Atelectasis, Postoperative

Malaysia
National Taiwan University Hospital

Not yet recruiting

Association With Low Compliance Bladder in Women With LUTS

Urinary Bladder, Overactive | Urinary Incontinence | Pelvic Organ Prolapse | Urinary Bladder Neck Obstruction

Taiwan
Xing Liu

Recruiting

Efficacy and Safety of Vitamin D in the Treatment of OAB-wet in Children

Overactive Bladder | Urinary Bladder, Overactive | Urinary Incontinence, Urge

China
National Yang Ming Chiao Tung University Hospital

Not yet recruiting

Early Intervention for Premyopic Children

Myopia | Preschool
Mackay Memorial Hospital

Recruiting

Efficacy of Combined Pharmacotherapy Versus Solifenacin With Vaginal Estrogen Cream for Women With Detrusor Overactivity

Urinary Bladder, Overactive | Effect of Drug

Taiwan
Seoul National University Hospital
Il-Yang Pharm. Co., Ltd.

Not yet recruiting

A Trial Evaluating the Clinical Efficacy and Safety of Hibero SR (Mirabegron) 50 mg and Ditropan (Oxybutynin Chloride) 10 mg in Children Between 5 and 18 Years With Overactive Bladder (OAB)

Overactive Bladder

Korea, Republic of
Jeanette Du

Not yet recruiting

Low Dose Atropine for Symptomatic Vitreous Floaters

Vitreous Floaters

United States
Sir Salimullah Medical College Mitford Hospital

Recruiting

Outcome of Moderate Severity in OPC Poisoning Patients When Treated With Pralidoxime (OPC)

Organophosphorus Poisoning

Bangladesh
University of California, Irvine
Merck Sharp & Dohme LLC

Not yet recruiting

Neuromuscular Blockade Comparison for GI-2 Recovery After Bowel Resection

Intestinal Disease

United States
Reinier de Graaf Groep

Not yet recruiting

REDucing Hot FLASHes in Women Using Endocrine Therapy. (REDFLASH)

Breast Cancer | Hot Flash Due to Medication
Medical University of Lodz

Not yet recruiting

Atropine vs Isoprenaline in the Invasive Diagnosis of Arrhythmias

Cardiac Arrhythmia | Supraventricular Arrhythmia

Poland
Islamic Hospital, Jordan
Jordan University of Science and Technology; Yarmouk University

Recruiting

Cycloplegic Refraction in Pediatric Patients With Esotropia

Refractive Errors | Vision Disorders | Esotropia | Cycloplegia

Jordan, Qatar
AstraZeneca

Recruiting

A Study to Investigate the Effect on Lung Function of an Approved COPD Treatment (BGF, With HFA Propellant) Compared to BGF Formulated With a New Propellant (HFO) in Participants 40 to 80 Years of Age With COPD

COPD (Chronic Obstructive Pulmonary Disease)

United States, Korea, Republic of, Argentina, Turkey, Vietnam, Malaysia, Philippines, Thailand, Hungary, Mexico, Canada, India, Bulgaria, Poland
He Eye Hospital

Not yet recruiting

Effect of Atropine on Pupil Size and Quality of Vision

Myopia, Progressive

China
AstraZeneca

Recruiting

A Study to Evaluate the Effect of Budesonide, Glycopyrronium, Formoterol Fumarate (BGF) Metered Dose Inhaler (MDI), Budesonide and Formoterol Fumarate (BFF) MDI and Placebo MDI on Exercise Parameters in Participants With Chronic Obstructive Pulmonary Disease (COPD). (ATHLOS)

Chronic Obstructive Pulmonary Disease

Germany, Spain, United States, China, Korea, Republic of, Argentina, United Kingdom, Canada
Ain Shams University

Recruiting

Effect of Hyoscine- Bromide on Duration of the First Stage of Labor

Labor

Egypt
Chonnam National University Hospital

Recruiting

Psychopharmacotherapy for Depressive Patients (BMDD-2022)

Major Depressive Disorder

Korea, Republic of

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