Search clinical trials for: METHOTREXATE

Total 1783 results

St. Jude Children's Research Hospital
AbbVie

Not yet recruiting

Adding Dasatinib Or Venetoclax To Improve Responses In Children With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia (ALL) Or Lymphoma (T-LLY) Or Mixed Phenotype Acute Leukemia (MPAL)

T-cell Lymphoma | T-cell Acute Lymphoblastic Leukemia | Mixed Phenotype Acute Leukemia

United States
Institute of Hematology & Blood Diseases Hospital...

Not yet recruiting

Efficacy and Safety of Low-dose Chemotherapy Plus Immuno-targeted Drugs in Newly Diagnosed Elderly/Unfit Ph- B-ALL

Precursor Cell Lymphoblastic Leukemia-Lymphoma
Murdoch Childrens Research Institute

Not yet recruiting

A Study Investigating the Change in Metabolism Phenotype in Paediatric, Adolescent & Young Adults With Hodgkin or Non-Hodgkin Lymphoma. (PEGASUS)

Hodgkin Lymphoma | Non Hodgkin Lymphoma

Australia
The Cleveland Clinic

Not yet recruiting

NonNarcotic Pain Control in Percutaneous Needle Tenotomy of Elbow

Chronic Pain | Elbow Pain

United States
Egymedicalpedia

Not yet recruiting

Evaluation of TWEAK in Plaque Psoriasis and Psoriatic Arthritis Patients

Plaque Psoriasis

Egypt
Siriraj Hospital

Not yet recruiting

The Comparison the CMV Infection and Reactivation After Allogeneic Hematopoietic Stem Cell Transplantation Between Standard Regimen, Methotrexate Plus Cyclosporin A, and Post-transplant Cyclophosphamide-based Regimen (CMV)

CMV Infection or Reactivation After Allogenic HSCT
Hospital de Clinicas de Porto Alegre

Recruiting

Use of Letrozole for Ectopic Pregnancy (EcZOL)

Ectopic Pregnancy

Brazil
National University Hospital, Singapore

Recruiting

Ma-Spore ALL 2020 Study

B Lymphoblastic Leukemia

Malaysia, Singapore
National Cancer Institute (NCI)

Not yet recruiting

Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia

B Acute Lymphoblastic Leukemia | Acute Leukemia of Ambiguous Lineage
University of Alabama at Birmingham

Not yet recruiting

Trial of 2 Step ATG for Acute GVHD Prevention Post Myeloablative Allogeneic Stem Cell Transplant

Myelodysplastic Syndromes | Myeloproliferative Disorders | Acute Leukemia | GVHD,Acute

United States
Peking University People's Hospital

Recruiting

Narlumosbartmab Combined With Neoadjuvant Chemotherapy in Bone-derived Malignancies With Osteolytic Lesions and Multinucleated Giant Cells

Malignant Bone Tumor

China
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Not yet recruiting

Methotrexate Combined With Tofacitinib in Rheumatoid Arthritis

Rheumatoid Arthritis
Assiut University

Not yet recruiting

Treatment of Ectopic Pregnancy by Low Dose of Methotrexate

Ectopic Pregnancy
Shanghai Institute Of Biological Products
The First Affiliated Hospital of Henan University of Science and Technology; First Affiliated Hospital Bengbu Medical College and other collaborators

Recruiting

A Phase Ib Clinical Trial of Peguricase for Injection With Methotrexate in Patients With Uncontrolled Gout.

Gout

China
National Institute of Geriatrics, Rheumatology...
Medical Research Agency, Poland

Not yet recruiting

Study of the Efficacy of Nintedanib+Tocilizumab in Patients With Systemic Sclerosis and Interstitial Lung Disease (NINTOC-TU)

Systemic Sclerosis | Interstitial Lung Disease

Poland
St. Jude Children's Research Hospital

Not yet recruiting

Identification of Necessary Information for Treatment Induction in Newly Diagnosed Acute Lymphoblastic Leukemia/Lymphoma

Acute Lymphoblastic Leukemia | Lymphoblastic Lymphoma | Mixed Phenotype Acute Leukemia

United States
University of Health Sciences Lahore

Recruiting

"Comparing Methotrexate Usage Techniques to Prevent Proliferative Vitreoretinopaty After Retinal Detachment Vitrectomy"

Proliferative Vitreoretinopathy

Pakistan
Diakonhjemmet Hospital

Not yet recruiting

A Post-trial Follow-up of MERINO Participants to Evaluate Long-term Effects of Methotrexate Treatment in Adults With Erosive Hand OA. (MERINO:2)

Hand Osteoarthritis | Erosive Osteoarthritis

Norway
Phramongkutklao College of Medicine and Hospital

Recruiting

Effect of Silymarin Against Methotrexate-induced Liver Injury in Rheumatic Diseases

Rheumatoid Arthritis | Psoriasis | Psoriatic Arthritis

Thailand
University of Alabama at Birmingham

Not yet recruiting

Trial of 2 Step ATG for Prevention of Acute GVHD Post Allogeneic Stem Cell Transplant

Myeloproliferative Disorders | Acute Leukemia | Myelodysplastic Syndrome

United States
Princess Maxima Center for Pediatric Oncology
Daiichi Sankyo

Recruiting

CHIP-AML22/Quizartinib: Quizartinib + Chemotherapy in Newly Diagnosed Pediatric FLT3-ITD+ and NPM1wt AML Patients (CHIP-AML22/Q)

Acute Myeloid Leukemia in Children

Netherlands
All India Institute of Medical Sciences, Bhubaneswar

Not yet recruiting

Efficacy and Safety of add-on Apremilast Versus add-on Methotrexate in Patients With Oral Lichen Planus

Oral Lichen Planus

India
Nantes University Hospital

Not yet recruiting

Study Testing Two Conditioning Regimen With a Single Prophylaxis of GVHD by Cyclophosphamide and Methotrexate Post-transplant in Patients Eligible for Matched-donor Allograft Transplantation (CY-MET-RIC)

Hematologic Malignancy | Graft Versus Host Disease
Children's Oncology Group

Not yet recruiting

A Study to Find the Highest Dose of Imetelstat in Combination With Fludarabine and Cytarabine for Patients With AML, MDS or JMML That Has Come Back or Does Not Respond to Therapy

Recurrent Acute Myeloid Leukemia | Recurrent Myelodysplastic Syndrome | Refractory Acute Myeloid Leukemia | Refractory Myelodysplastic Syndrome | Recurrent Juvenile Myelomonocytic Leukemia
medac GmbH

Not yet recruiting

Efficacy and Safety of Methotrexate Versus Placebo in Adults With Atopic Dermatitis.

Moderate to Severe Atopic Dermatitis
Mostafa Bahaa

Recruiting

Paroxetine Safety and Efficacy in Rheumatoid Arthritis

Rheumatoid Arthritis

Egypt
Amgen

Recruiting

A Trial to Investigate the Non-inferiority of Pegloticase Administered Every 4 Weeks (Q4W) With MTX Compared With Every 2 Weeks (Q2W) With MTX in Participants With Uncontrolled Refractory Gout

Gout

United States
Instituto Nacional de Cancer, Brazil

Recruiting

Evaluation of Prophylactic Photobiomodulation Therapy in Patients With Osteosarcoma (PBMT/MTX)

Mucositis Oral

Brazil
National Cancer Institute (NCI)

Not yet recruiting

Adding Targeted Drugs to Usual Chemotherapy for Adults With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia (T-ALL) and T-Cell Lymphoblastic Lymphoma (T-LBL)

T Acute Lymphoblastic Leukemia | T Lymphoblastic Lymphoma
University of Chicago

Not yet recruiting

A Study to Investigate LP-118, Ponatinib, Vincristine and Dexamethasone in Relapsed/Refractory Acute Lymphoblastic Leukemia (ALL) or Lymphoblastic Lymphoma (LBL)

Lymphoblastic Lymphoma | Acute Leukemia | Lymphoblastic Leukemia

United States
Brigham and Women's Hospital

Not yet recruiting

Drug Screening Using IMD in Bladder Cancer

Muscle Invasive Bladder Urothelial Carcinoma

United States
Tongji Hospital
Geneplus-Beijing Co. Ltd.; Chinese Cooperative Group of Liver Cancer (CCGLC)

Recruiting

Combined DEB-TACE, Lenvatinib and Pucotenlimab as Conversion Therapy for Unresectable Intrahepatic Cholangiocarcinoma (CCGLC-012)

Cholangiocarcinoma Non-resectable

China
St. Jude Children's Research Hospital
Syndax Pharmaceuticals

Recruiting

Study of Revumenib, Azacitidine, and Venetoclax in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia

Refractory Acute Myeloid Leukemia | Acute Leukemia of Ambiguous Lineage | Relapsed Acute Myeloid Leukemia

United States
PETHEMA Foundation

Not yet recruiting

Treatment Protocol for Newky Diagnosed Adult Ph Positive ALL (LALPh2022)

Lymphoblastic Leukemia | Adult ALL | Philadelphia-Positive ALL
University of Palermo

Not yet recruiting

Cornual Pregnancy: Results of a Single-center Retrospective Experience and Systematic Review on Reproductive Outcomes

Ectopic Pregnancy
University of Texas Southwestern Medical Center
assertio Therapeutics, Inc

Not yet recruiting

Intra-nasal Ketorolac for Acute Ureteral Stent-associated Pain Following Ureteroscopy for Stone Disease

Urolithiasis | Post Operative Pain | Ureter Calculi | Stent Complication

United States
Assiut University

Not yet recruiting

Methotrexate Alone vs Combination With Excimer Light in Nail Psoriasis

Nail Psoriasis

Egypt
City of Hope Medical Center
National Cancer Institute (NCI)

Not yet recruiting

Ruxolitinib With Tacrolimus and Methotrexate for the Prevention of Graft Versus Host Disease in Pediatric and Young Adult Patients Undergoing Allogeneic Hematopoietic Cell Transplant for Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or Myelodysplastic Syndrome

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Myelodysplastic Syndrome

United States
National Cancer Institute (NCI)

Not yet recruiting

A Study Comparing the Combination of Dasatinib and Chemotherapy Treatment With or Without Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or Philadelphia Chromosome-Like (Ph-Like) ABL-Class B-Cell Acute Lymphoblastic Leukemia (B-ALL)

B Acute Lymphoblastic Leukemia
Sohag University

Not yet recruiting

Evaluation of High Dose Methotrexate Toxicity

Methotrexate Toxicity
Nationwide Children's Hospital
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Not yet recruiting

GERD Infant Feeding Therapeutics Trial (GIFT Trial) (GIFT)

GERD in Infants
Hee Young Ju

Not yet recruiting

Treatment of Newly Diagnosed Standard Risk Acute Lymphoblastic Leukemia in Children

Lymphoblastic Leukemia in Children
Al-Azhar University

Not yet recruiting

Methotrexate Versus Triamcinilone Acetonide in Treatment of Recalcitrant Alopecia Areata

Alopecia Areata

Egypt
University of Illinois at Chicago

Recruiting

BRE-08 Phase II Study of CMC Regimen for Early Stage Breast Cancer (BRE-08)

Breast Cancer

United States
Hunan Province Tumor Hospital
Xiangya Hospital of Central South University

Recruiting

The Efficacy and Safety of IBI363 in Solid Tumors. (Promise)

Advanced Solid Tumor

China
Cairo University

Not yet recruiting

Tissue and Serum Level of NLRP1, NLRP3 and Il-18 in Early Stages of mf Patients

Early Disease Onset
Academisch Medisch Centrum - Universiteit van Amsterdam...
Celltrion

Recruiting

inDuctIon tREatment With subCuTaneous Infliximab for Crohn's Disease (DIRECTCD)

Bowel Disease | Inflammatory Disease | Disease Crohn

Netherlands
Instituto do Cancer do Estado de São Paulo
Libbs Farmacêutica LTDA

Recruiting

Bortezomib-based Regimen for Refractory or Relapsed Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia, in Relapse | Acute Lymphoblastic Leukemia With Failed Remission

Brazil
Ohio State University Comprehensive Cancer Center

Recruiting

Pharmacogenomics Effects on High-Dose Methotrexate Clearance in Patients With Diffuse Large B-Cell Lymphoma

Diffuse Large B-Cell Lymphoma | Central Nervous System Lymphoma

United States
Alexion Pharmaceuticals, Inc.

Not yet recruiting

Mitigate Immune-Mediated Loss of Therapeutic Response to Asfotase Alfa (STRENSIQ®) for Hypophosphatasia (RESTORE)

Hypophosphatasia

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