Search clinical trials for: Microbiome Metabolic Therapy

Total 104597 results

Western University

Not yet recruiting

Akkermansia Muciniphilia and Metabolic Side Effects of ADT

Obesity | Diabetes | Metabolic Syndrome | Bone Diseases | Hyperlipidemias | Prostate Cancer | Cardiovascular Morbidity
Anna Baiges
Hospital Universitario Ramon y Cajal; Instituto de Salud Carlos III; Gregorio...

Recruiting

Role of Sarcopenia and Nutritional/Physical Therapy Intervention in Post-TIPS Hepatic Encephalopathy

Hepatic Encephalopathy | Sarcopenia | Cirrhosis, Liver

Spain
Penn State University
United States Department of Agriculture (USDA)

Recruiting

Probiotics and Gut Health (PRO)

Metabolic Syndrome

United States
University of Colorado, Denver

Recruiting

The Effect of PPI Therapy on Weight, Gut Microbiome, and Expression of GPR41 and GPR43

Obesity | Gastroesophageal Reflux Disease

United States
Indiana University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

eIMPACT-DM Pilot Trial: Depression Treatment to Reduce Diabetes Risk

Depression | Insulin Resistance | PreDiabetes | Type 2 Diabetes | Depressive Symptoms | Major Depressive Disorder | Dysthymic Disorder

United States
University of Connecticut

Completed

Blackcurrants Modify Gut Microbiota and Reduce Osteoporosis and CVD Risk

Cardiovascular Diseases | Gut Microbiota | Postmenopausal Osteoporosis

United States
Kaleido Biosciences

Terminated

UNLOCKED: A Phase 2, Open-label Trial With KB195 in Subjects With a Urea Cycle Disorder (UNLOCKED)

Urea Cycle Disorder

Belgium, United States, Spain, United Kingdom, Germany, Switzerland, Turkey
Kaleido Biosciences

Completed

A Clinical Study to Assess the Effects of KB295 in Patients With Ulcerative Colitis (UC) on Gut Microbiota Structure and Function

Ulcerative Colitis

Ireland, United States
Kaleido Biosciences

Completed

An Observational Clinical Study to Evaluate COVID-19 Symptoms in "Long Hauler" Patients Who Participated in K031-120 or K032-120

COVID-19

United States
Kaleido Biosciences

Completed

A Clinical Study to Assess the Physiologic Effects of KB109 in Patients With COVID-19 on Gut Microbiota Structure and Function

Mild-to-Moderate COVID-19

United States
Kaleido Biosciences

Completed

A Clinical Study to Assess the Natural History of COVID-19 and Effects of KB109 and Supportive Self-care in Outpatients With Mild-to-moderate COVID-19

Mild-to-moderate COVID-19

United States
Kaleido Biosciences

Terminated

VITORA: Clinical Study to Evaluate the Effect of KB109 on the Gut Microbiome in Subjects Whose Gastrointestinal Tracts Are Colonized With Multiple Drug-resistant Organisms (VITORA)

Vancomycin-Resistant Enterococcus, Extended-Spectrum Beta Lactamase-Producing Enterobacteriaceae, or Carbapenem-Resistant Enterobacteriaceae Colonized Subjects

United States
Microbiome Health Research Institute
University of Cape Town

Terminated

Transfer of Healthy Gut Flora for Restoration of Intestinal Microbiota Via Enema for Patients in the Rehabilitative Phase of Malnutrition (THRIVE)

Moderate Acute Malnutrition | Severe Acute Malnutrition

South Africa
Kaleido Biosciences

Completed

A Clinical Study to Assess the Effect of Increasing Intake Amounts of Two Novel Glycans on the Gut Microbiota of Healthy Subjects

Healthy

United States
Kaleido Biosciences

Completed

A Clinical Study to Assess the Effect of Novel Glycans on Nitrogen Metabolism of the Gut in Healthy Subjects

Healthy

United States
McGill University

Recruiting

Accuracy of a Continuous Ketone Monitoring (CKM) System in Individuals With Type 1 Diabetes on Insulin Pump Therapy. (CKM 1)

type1diabetes

Canada
GeneCradle Inc

Recruiting

Evaluation of Safety and Efficacy of Gene Therapy Drug in the Treatment of Spinal Muscular Atrophy (SMA) Type 3 Patients

Spinal Muscular Atrophy Type 3

China
University of Oxford
Oxford Brookes University; Oxford University Hospitals NHS Trust; Scholar Rock... and other collaborators

Not yet recruiting

Acceptability, Feasibility, Safety and Efficacy of a Optimized Rehabilitation Program for Treated Patients With Spinal Muscular Atrophy (SMA) (ACE SMA) (ACE SMA)

Spinal Muscular Atrophy

United Kingdom
Emory University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Not yet recruiting

Automated Insulin Delivery for Inpatients With Dysglycemia (AIDING)

Type 1 Diabetes | Type 2 Diabetes

United States
Peking University People's Hospital
Xingtai People's Hospital; Hebei Provincial People's Hospital

Not yet recruiting

Efficacy and Safety of an Artificial-pancreas-like Learning-based Control in Type 1 Diabetes on Multiple Daily Injection Therapy (ELITE)

Diabetes Mellitus, Type 1
Jin Lu, MD

Recruiting

Daratumumab, Bortezomib, Cyclophosphamide, and Dexamethasone Therapy for Patients With MIDD

Monoclonal Gammopathy of Renal Significance

China
Masaryk University

Recruiting

Effect of Speech Therapy in Combination With Non-invasive Brain Stimulation on Speech of Patients With Parkinson's Disease

Parkinson Disease

Czechia
Peking University First Hospital

Not yet recruiting

Evaluation of Efficacy and Safety of Combination Therapy of Henagliflozin Proline, Retagliptin and Metformin in New Diagnosed Type 2 Diabetes Patients

Type 2 Diabetes
University of Nove de Julho

Not yet recruiting

Action of Photodynamic Therapy on Wound Quality and Tissue Repair in the Diabetic Foot

Diabetic Foot Ulcer

Brazil
University College Cork

Recruiting

The Fibre Full Study

Overweight and Obesity

Ireland
Shanghai Changzheng Hospital

Recruiting

UCMSCs Combined With Standard Therapy for the Treatment of Newly Diagnosed Type 1 Diabetes

Newly Diagnosed Type 1 Diabetes Mellitus

China
ETS Wound Care, LLC
Professional Education and Research Institute

Recruiting

Bioresorbable Glass Fiber Matrix in the Treatment of Diabetic Foot Ulcers (BGWM)

Diabetic Foot | Diabetic Foot Ulcer | Ulcer Foot

United States
Universiti Sains Malaysia

Recruiting

Electrolyte Balance Effects of Sterofundin Versus Normal Saline in Diabetic Ketoacidosis

Treatment Diabetic Ketoacidosis, Electrolyte Balance Effects

Malaysia
Petra Zimmermann
ETH Zurich; University of Luzern

Not yet recruiting

NapBiome: Targeting Gut Microbiota and Sleep Rhythm to Improve Developmental and Behavioral Outcomes in Early Childhood (NapBiome)

Neurobehavioral Manifestations | Sleep Problem

Switzerland
Beijing Hospital of Traditional Chinese Medicine

Not yet recruiting

A Multicentre Randomized Controlled Clinical Study on the Chitosan Nanocrystalline Qinteng Huoxue Runji Ointment Therapy for Psoriasis With Blood Stasis Syndrome.

Plaque Psoriasis
Anhui Provincial Cancer Hospital
Anhui Kecheng intelligent health technology Co., LTD

Recruiting

Safety and Efficacy of Intraperitoneal Injection of METR-NK Cells as Neoadjuvant Therapy for Advanced Epithelial Ovarian Cancer

Ovarian Cancer

China
The Children's Hospital of Zhejiang University...
Leman Biotech Co., Ltd

Recruiting

Safety and Efficacy of Metabolically Armed CD19 CAR-T Cells (Meta10-19) in the Treatment of Relapsed and/or Refractory CD19-positive B Cell Hematological Malignancies Clinical Research

Acute Lymphoblastic Leukemia | Non-hodgkin Lymphoma

China
GeneCradle Inc

Recruiting

Evaluation of the Safety and Efficacy of Late-onset Pompe Disease Gene Therapy Drug

Pompe Disease (Late-onset)

China
Hebrew SeniorLife
Beth Israel Deaconess Medical Center; Tufts University; MaineHealth; Solarea Bio...

Not yet recruiting

Synbiotic to Attenuate Resorption of the Skeleton (STARS)

Inflammation | Aging | Osteoporosis

United States
Foundation University Islamabad

Recruiting

Effects of Eccentric Training on Glycemic Control and Quality of Life in Patients With Type II Diabetes Mellitus

Type II Diabetes Mellitus

Pakistan
University of Illinois at Urbana-Champaign

Recruiting

Personalized GI Motility Responses to Diet

Cardiovascular Diseases | Dysbiosis | Gastrointestinal Dysfunction | Nutritional and Metabolic Diseases

United States
Wang Siqi
China-Japan Friendship Hospital

Not yet recruiting

Research on Changes in Intestinal Barrier Function and Gut Microbiome in Patients With Type 2 Diabetes After Duodenal Mucosal Resurfacing (DMR) (DMR-IBF-GM)

Type 2 Diabetes Mellitus
Epicentre
Epicentre, Niger; National Nutrition Direction, Niger; Ministry of Public Health... and other collaborators

Recruiting

Effectiveness of a Microbiome-directed Food to Promote Programmatic and Sustained Nutritional Recovery Among Children With Uncomplicated Acute Malnutrition

Malnutrition, Child

Niger
University Hospital, Basel, Switzerland

Not yet recruiting

Validation of New Diagnostic Indices to Simplify Hyponatremia Therapy Assessment in Patients on Thiazide Diuretics

Thiazide Associated Hyponatremia

Switzerland
National Cheng-Kung University Hospital

Not yet recruiting

Function Definition and Clinical Validation of Digital Health App: Using Weight Management as An Example

Weight Loss | Body Fat Rate Loss | Body Composition Change
University of Salerno

Not yet recruiting

Efficacy and Safety of Bempedoic Acid in Association With Anti-PCSK9 and Ezetimibe in Statin-intolerant Patients (BESAFE)

Cardiovascular Diseases | Dyslipidemias | Lipid Metabolism Disorders | Statin Adverse Reaction
Pennington Biomedical Research Center
U.S. Army Medical Research and Development Command

Not yet recruiting

Military Health and Nutrition Examination Study (MHANES)

Cardiovascular Diseases | Hypertension | Dyslipidemias | Type 2 Diabetes

United States
David Franco Castellanos
Jesús Ángel Seco Calvo; Javier Tejada Garcia

Not yet recruiting

How Does Pianistic Musical Training Influence the Development of Alzheimer's Disease?

Dementia | Neurologic Disorder | Dementia, Vascular | Cognitive Decline | Dementia, Mixed | Dementia With Lewy Bodies | Neurologic Dysfunction | Dementia of Alzheimer Type | Neurologic Deficits | Dementia Frontal

Spain
Ali Aminian

Not yet recruiting

Fibrosis Lessens After Metabolic Surgery (FLAMES)

Obesity | Liver Fibrosis | Non-Alcoholic Fatty Liver Disease | Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD) | Metabolic Dysfunction-Associated Steatohepatitis (MASH)

United States, Sweden, Ireland, Finland, United Kingdom, Spain, Switzerland, Brazil, Canada, Italy, Kuwait, India, Mexico
Wake Forest University
University of South Florida

Not yet recruiting

Probiotic Effect on Dietary Nitrate to Plasma Nitrite Production ( OPEDNPN ) (OPEDNPN)

Cardiovascular Diseases | Hypertension | Diabetes
Taipei Veterans General Hospital, Taiwan

Recruiting

The Efficacy of Weight-loss Diet Decision-making Based on Initial Gut Metabolic Modules (GMMs)

Weight Loss

Taiwan
University of Skövde
Albert Einstein College of Medicine; Uppsala University; Göteborg University; University... and other collaborators

Not yet recruiting

The MIND-GUT Digital Pilot Intervention Study (MINDGUT)

Obesity | Stress | Anxiety | Depressive Symptoms | Dysbiosis | Eating Habit

Sweden
Children's Oncology Group

Not yet recruiting

A Study of Lower Radiotherapy Dose to Treat Children With CNS Germinoma

Central Nervous System Germinoma | Diabetes Insipidus | Pineal Region Germinoma | Suprasellar Germinoma
University Ghent
University Hospital, Ghent

Not yet recruiting

Effect of High Intensity Exercise Rehabilitation on Liver Function and Insulin Sensitivity in Patients With MASLD (CENSORIAL)

Exercise Therapy | Metabolic Dysfunction-associated Steatotic Liver Disease
Integrative Phenomics
Assistance Publique - Hôpitaux de Paris; Assistance Publique Hopitaux De Marseille and other collaborators

Not yet recruiting

Individual Factors Related to Chronic Low-grade Inflammation and Cardiometabolic Disease Risk (PINEAPPL)

Hypertension | Healthy | Obesity | Overweight | Metabolic Syndrome | Hypercholesterolemia | Risk Factor, Cardiovascular | Abdominal Obesity | Normal Weight Adults | Low-grade Inflammation | Metabolically Healthy Controls

Search clinical trials for: Microbiome Metabolic Therapy

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