Search clinical trials for: Minimal Toxicity

Total 4080 results

University of Oklahoma

Not yet recruiting

Relugolix + Enzalutamide Study in High-Risk Prostate Cancer

Androgen Deprivation Therapy | Locally Advanced Prostate Cancer

United States
Instituto do Cancer do Estado de São Paulo
Servier

Recruiting

Adult Acute Lymphoblastic Leukemia Treated With Pediatric Regimen in Brazil (BRALLA)

Acute Lymphoid Leukemia | Chemotherapeutic Toxicity | Minimal Residual Disease | Gene Abnormality

Brazil
Centre Francois Baclesse, Luxembourg
BIONEXT; NEOLYS DIAGNOSTICS - ALARA GROUP

Not yet recruiting

Pre-therapeutic Analysis of the Individual Radiosensitivity of Cancer Patients in Luxembourg (APRI-Lux): Prospective National Interventional Study With Minimal Risk

Cancer | Radiation Toxicity | Radiosensitivity
Hospital General de Mexico

Recruiting

Efficacy of the Use of Bortezomib for the Treatment of Relapsed Leukemia or Positive MRD

Acute Lymphoblastic Leukemia, in Relapse | Chemotherapeutic Toxicity | Minimal Residual Disease

Mexico
NovoCure GmbH
Merck Sharp & Dohme LLC

Recruiting

EF-36/Keynote B36: A Pilot, Randomized, Open-label Study of Tumor Treating Fields (TTFields, 150 kHz) Concomitant With Pembrolizumab for First Line Treatment of Advanced or Metastatic Non-small Cell Lung Cancer (KEYNOTE B36)

Non-small Cell Lung Cancer

United States
NovoCure Ltd.

Recruiting

Open-Label Pilot Study of OPTUNE® With High Density Transducer Arrays for the Treatment of Recurrent GBM

Glioblastoma Multiforme

Czechia
SWOG Cancer Research Network
National Cancer Institute (NCI)

Recruiting

S1501 Carvedilol in Preventing Cardiac Toxicity in Patients With Metastatic HER-2-Positive Breast Cancer

Cardiotoxicity | Recurrent Breast Carcinoma | HER2/Neu Positive | Metastatic Malignant Neoplasm in the Brain | Stage IV Breast Cancer AJCC v6 and v7

United States, Korea, Republic of, Puerto Rico, Saudi Arabia
NovoCure Ltd.

Completed

Effect of Tumor Treating Fields (TTFields, 200 kHz) Concomitant With Weekly Paclitaxel for the Treatment of Recurrent Ovarian Cancer (ENGOT-ov50 / GOG-3029 / INNOVATE-3)

Ovarian Cancer

United States, Israel, Belgium, Netherlands, Hungary, Germany, Poland, Canada, Austria, Czechia, Italy, Spain, Switzerland
University Hospital, Basel, Switzerland

Completed

Probability of Optimal Target Attainment of Amikacin in Patients With Febrile Neutropenia During Treatment for a Hematological Disorder

Febrile Neutropenia (FN)

Switzerland
Weill Medical College of Cornell University
Teleflex; NeoTract, Inc.

Suspended

Urolift Pre-SBRT for Reduced Urinary Toxicity in Patients With BPH and Prostate Cancer.

Benign Prostatic Hyperplasia

United States
NovoCure GmbH

Active, not recruiting

Effect of Tumor Treating Fields (TTFields) (150 kHz) Concurrent With Standard of Care Therapies for Treatment of Stage 4 Non-small Cell Lung Cancer (NSCLC) Following Platinum Failure (LUNAR)

NSCLC | Nonsmall Cell Lung Cancer

United States, Poland, Hong Kong, China, Spain, Serbia, Croatia, France, Canada, Netherlands, Austria, Belgium, Bulgaria, Czechia, Germany, Hungary, Italy, Switzerland
NovoCure Ltd.

Active, not recruiting

Effect of Tumor Treating Fields (TTFields, 150 kHz) as Front-Line Treatment of Locally-advanced Pancreatic Adenocarcinoma Concomitant With Gemcitabine and Nab-paclitaxel (PANOVA-3)

Pancreas Adenocarcinoma

United States, China, Belgium, Czechia, Korea, Republic of, Spain, Hong Kong, France, Australia, Italy, Hungary, Germany, Croatia, Canada, Mexico, Israel, Austria, Switzerland, Brazil, Poland
NovoCure GmbH

Active, not recruiting

Pivotal, Open-label, Randomized Study of Radiosurgery With or Without Tumor Treating Fields (TTFields) for 1-10 Brain Metastases From Non-small Cell Lung Cancer (NSCLC).

Brain Metastases From Non-small Cell Lung Cancer (NSCLC)

United States, China, Israel, Spain, Austria, Canada, Hong Kong, Germany, France, Bulgaria, Croatia, Hungary, Italy, Poland, Serbia
NovoCure GmbH

Unknown

Effect of Tumor Treating Fields (TTFields, 150kHz) Concomitant With Sorafenib For Advanced Hepatocellular Carcinoma (HCC) (HEPANOVA)

Hepatocellular Carcinoma

Italy, Czechia, France, Germany, Poland, Spain
NovoCure GmbH
Zai Lab (Shanghai) Co., Ltd.

Unknown

Effect of Tumor Treating Fields (TTFields, 150 kHz) Concomitant With Chemotherapy as First Line Treatment of Unresectable Gastroesophageal Junction or Gastric Adenocarcinoma

Gastric Cancer | GastroEsophageal Cancer

Hong Kong
NovoCure Ltd.

Completed

Safety and Efficacy of TTFields (150 kHz) Concomitant With Pemetrexed and Cisplatin or Carboplatin in Malignant Pleural Mesothelioma (STELLAR)

Malignant Pleural Mesothelioma

Netherlands, Italy, Germany, Belgium, France, Poland, Spain
Gruppo Italiano Malattie EMatologiche dell'Adulto

Unknown

AML Treatment in Untreated Adult Patients (LAM99P)

Leukemia, Myelocytic, Acute

Italy
NovoCure Ltd.

Unknown

Safety Feasibility and Effect of TTFields (150 kHz) Concomitant With Gemcitabine or Concomitant With Gemcitabine Plus Nab-paclitaxel for Front-line Therapy of Advanced Pancreatic Adenocarcinoma (PANOVA)

Pancreatic Adenocarcinoma

Spain, Switzerland
Novartis Pharmaceuticals

Completed

Safety and Efficacy Evaluation of Two Year Imatinib Treatment in Adjuvant Gastrointestinal Stromal Tumor (GIST) (INV555)

Gastrointestinal Stromal Tumors

Saudi Arabia, Taiwan, Turkey, Egypt, Thailand, Russian Federation, South Africa, Lebanon, India, Tunisia, Algeria, Jordan
NovoCure Ltd.

Completed

Effect of NovoTTF-100A Together With Temozolomide in Newly Diagnosed Glioblastoma Multiforme (GBM)

Glioblastoma Multiforme

United States, Spain, France, Canada, Korea, Republic of, Austria, Israel, Czech Republic, Germany, Italy, Sweden, Switzerland
NovoCure Ltd.

Unknown

Safety, Feasibility and Effect of TTFields (200 kHz) Concomitant With Weekly Paclitaxel in Recurrent Ovarian Carcinoma (INNOVATE)

Ovarian Carcinoma

Switzerland, Belgium, Germany, Spain
NovoCure Ltd.

Unknown

Effect of TTFields (150kHz) in Non-small Cell Lung Cancer (NSCLC) Patients With 1-5 Brain Metastases Following Optimal Standard Local Treatment (COMET)

1-5 Brain Metastases From Non-Small Cell Lung Cancer

Poland, Czech Republic, Italy, France, Spain
NovoCure Ltd.

Terminated

Post-approval Study of NovoTTF-100A in Recurrent GBM Patients

Recurrent Glioblastoma Multiforme

United States
Asan Medical Center

Completed

Donor Stem Cell Transplant or Bone Marrow Transplant in Treating Patients With Acute Myeloid Leukemia in Remission

Leukemia

Korea, Republic of
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Gemtuzumab Ozogamicin in Treating Young Patients With Newly Diagnosed Acute Myeloid Leukemia Undergoing Remission Induction and Intensification Therapy

Leukemia

United States, Canada, Australia, Puerto Rico, Switzerland
Sidney Kimmel Cancer Center at Thomas Jefferson...

Completed

Amifostine and Combination Chemotherapy in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia

Leukemia | Drug/Agent Toxicity by Tissue/Organ

United States
NovoCure Ltd.

Completed

Effect of NovoTTF-100A in Recurrent Glioblastoma Multiforme (GBM)

Recurrent Glioblastoma Multiforme

United States, Israel, Switzerland, Austria, Czech Republic, France, Germany
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Umbilical Cord Blood Transplantation in Treating Patients With High-Risk Hematologic Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Myelodysplastic/Myeloproliferative Diseases | Graft Versus Host Disease

United States
Universidad de Murcia

Recruiting

Three Types of Papilla Incision in Periodontal Surgery

Periodontitis | Periodontal Diseases | Periodontal Pocket

Spain
Thanawan Longsuwan

Not yet recruiting

Effect of Topical Tranexamic Acid on Postoperative Drainage in Minimally Invasive Transforaminal Lumbar Interbody Fusion (MI-TLIF)

Surgical Wound | Degenerative Spine Diseases
Amy Wagner
The Beckwith Institute

Not yet recruiting

mindBEAGLE: Unlocking Functional Communication for Patients With Disorders of Consciousness

Disorders of Consciousness

United States
Noordwest Ziekenhuisgroep
Borstkanker Onderzoek Groep; Comprehensive Cancer Centre The Netherlands; Dutch... and other collaborators

Not yet recruiting

Mitigating Toxicity by Electronic Health Portal-mediated Interactive Monitoring of Patient-reported Side Effects (eChemoCoach)

Breast Cancer | eHealth | Self Management | Symptom Monitoring
Odense University Hospital

Recruiting

OPC5: Pressurized IntraThoracic Aerosol Chemotherapy (PITAC) in Patients With Malignant Pleural Effusion.

Quality of Life | Pleural Carcinomatosis | Chemotherapy Effect | Pleural Neoplasms | Chemotherapeutic Toxicity | Malignant Pleural Effusion | Pleural Cavity Effusion

Denmark
Insel Gruppe AG, University Hospital Bern
Monash University

Not yet recruiting

CPAx: Responsiveness and Minimal Clinically Important Difference

Muscle Weakness | Critical Illness Myopathy | Physical Inactivity | Critical Illness Polyneuropathy | Critical Illness Polyneuromyopathy

Switzerland
Nantes University Hospital

Not yet recruiting

Evaluation of a Range of Dermo-cosmetic Products to Treat Skin and Nail Toxicity Linked to Bispecific Anti-GPRC5D Bispecific Antibodies in Multiple Myeloma Patients". Myeloma". Descriptive Pilot Study (DELICATESSE)

Myeloma Multiple
VA Office of Research and Development

Not yet recruiting

Ketamine-assisted Integrative Treatment for Veterans With Chronic Low Back Pain and Comorbid Depression

Depression | Chronic Low Back Pain

United States
Shanghai University of Traditional Chinese Medicine
Shanghai Minimally Invasive Surgery Center

Not yet recruiting

Clinical Evaluation of Acupuncture Treatment on Alzheimer's Disease in APOE e4 Carriers and Non-Carriers

Cognitive Impairment | Alzheimer Disease

China
Peter MacCallum Cancer Centre, Australia
AbbVie

Not yet recruiting

MRD-Directed Consolidation With Epcor-only or Epcor-R2 Post Anti-CD19 CAR TCell Therapy for Large B-Cell Lymphoma (EpLCART)

Relapsed/Refractory Large B-cell Lymphoma

Australia
Fondazione Policlinico Universitario Agostino Gemelli...

Not yet recruiting

Minimally Invasive Simple Hysterectomy in Low Risk Cervical Cancer (LASH)

Cervical Cancer | Cervix Cancer
Institut de cancérologie Strasbourg Europe
Centre de recherche du Centre hospitalier universitaire de Sherbrooke

Recruiting

Prediction of Radiotherapy Efficacy in Patients With Triple-negative Breast Cancer (TNBC-RT2023)

Triple-negative Breast Cancer

France
Royal Marsden NHS Foundation Trust

Not yet recruiting

LATe TreatmENT Related Toxicity in Melanoma (LATENT) (LATENT)

Melanoma

United Kingdom
The First Affiliated Hospital of Soochow University

Not yet recruiting

Treatment of High-risk Newly Diagnosed Multiple Myeloma With Minimal Residual Disease Detection

Multiple Myeloma | Newly Diagnosed | MRD | High Risk
National Cancer Institute (NCI)

Not yet recruiting

A UGT1A1 Genotype-Directed Study of Belinostat Pharmacokinetics and Toxicity

Carcinoma, Neuroendocrine | Tumor, Neuroendocrine | Tumors, Neuroendocrine | Neuroendocrine; Carcinoma | Small Cell; Receptors

United States
Air Force Military Medical University, China
First Affiliated Hospital Xi'an Jiaotong University; Shaanxi Provincial People... and other collaborators

Not yet recruiting

Efficacy and Safety of Tacrolimus in Combination With Ripertamab in the Initial Treatment of Patients With MCD

Minimal Change Disease
Washington University School of Medicine
American Academy of Clinical Toxicology

Not yet recruiting

Rivastigmine to Prevent Recurrence of Antimuscarinic Delirium (RIVA-AP)

Anticholinergic Toxicity

United States
Hospital Universitari Vall d'Hebron Research Institute

Recruiting

The Preoperative Administration of ICG Improves Tumor Detection in Patients Undergoing Minimally Invasive Hepatic Resection Guided by Conventional Intraoperative Ultrasound.

Liver Tumor; Surgery

Spain
Exact Sciences Corporation
Labcorp Corporation of America Holdings, Inc

Recruiting

First CORRECT Study of Minimal Residual Disease (MRD) Detection in Colorectal Cancer (MRD)

Colorectal Cancer

United Kingdom, Spain, Italy, Israel
Fondazione Policlinico Universitario Agostino Gemelli...

Not yet recruiting

Evaluation of Ultraaccelerated High Dose Rate Intrauterine Interventional Radiotherapy (EROS3)

Locally Advanced Cervical Carcinoma
Dr. Lutfi Kirdar Kartal Training and Research Hospital

Not yet recruiting

VCare Versus SecuFix Uterine Manipulator for Total Laparoscopic Hysterectomy

Operative Time | Length of Hospital Stay | Perioperative Complications
Beijing Hospital of Traditional Chinese Medicine

Not yet recruiting

A Multicentre Randomized Controlled Clinical Study on the Chitosan Nanocrystalline Qinteng Huoxue Runji Ointment Therapy for Psoriasis With Blood Stasis Syndrome.

Plaque Psoriasis

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