Search clinical trials for: MitraClip NTR

Total 268 results

Nantes University Hospital
Abbott; Ministère de la Santé

Recruiting

Multicentre Study of MITRACLIP® Transcatheter Mitral Valve Repair in Patients With Severe Primary Mitral Regurgitation Eligible for High-risk Surgery (MITRA-HR)

Mitral Regurgitation

France, Monaco
Abbott Medical Devices
Abbott

Completed

The MitraClip® EXPAND Study of the Next Generation of MitraClip® Devices

Mitral Regurgitation | Mitral Valve Regurgitation

Netherlands, United Kingdom, United States, Spain, Israel, Germany, Italy, Switzerland
Attikon Hospital

Recruiting

"Hypotension Probability Indicator" in TAVI/MitraClip for Hypotension Management

Hypotension During Surgery | Prevention of Hypotension

Greece
Fundación para la Investigación Biosanitaria del...
Meditrial Europe Ltd.

Not yet recruiting

Early Transcatheter Mitral Valve Repair After Myocardial Infarction (EMCAMI)

Acute Mitral Regurgitation

Spain, Italy, Netherlands, Israel
Janssen Research & Development, LLC

Recruiting

A Study of JNJ-77242113 for the Treatment of Participants With Moderate to Severe Plaque Psoriasis (ICONIC-ADVANCE 2)

Plaque Psoriasis

United States, Korea, Republic of, Taiwan, Germany, Poland, Brazil, Spain, Hungary, Australia, Canada, Romania
IRCCS San Raffaele

Recruiting

Multiparametric Protocol for Assessment of Intraprocedural Result of MITRACLIP Procedure (IPCLIP-2020)

Residual Mitral Regurgitation

Italy
South Valley University

Recruiting

Monitoring Effect Of Shock Wave On Microcirculation Changes In Type2 Diabetes Mellitus

Shock Wave and Nitric Oxide

Egypt
Janssen Research & Development, LLC

Recruiting

Enhanced Dermatological Care to Reduce Rash and Paronychia in Epidermal Growth Factor Receptor (EGRF)-Mutated Non-Small Cell Lung Cancer (NSCLC) Treated First-line With Amivantamab Plus Lazertinib (COCOON)

Carcinoma, Non-Small-Cell Lung

United States, Taiwan, Korea, Republic of, Malaysia, Turkey, France, Spain, China, Germany, Argentina
Janssen Research & Development, LLC

Recruiting

A Study of JNJ-77242113 in Participants With Moderately to Severely Active Ulcerative Colitis (ANTHEM-UC)

Colitis, Ulcerative

Korea, Republic of, Canada, United States, Australia, Czechia, Malaysia, Germany, Turkey, Japan, Belgium, Hungary, Italy, Spain, China, Poland, United Kingdom, Brazil, France, Argentina, Romania, India
Academisch Medisch Centrum - Universiteit van Amsterdam...
Radboud University Medical Center; Obesitas Kliniek B.V.

Recruiting

Predictors of Weight Loss and Metabolic Health After Bariatric Surgery

Obesity, Morbid | Bariatric Surgery Candidate | Insulin Sensitivity | Feeding Behavior

Netherlands
TYK Medicines, Inc

Recruiting

A Study of TY-2136b in Patients With Advanced Solid Tumors Harboring ALK, ROS1 or NTRK1-3 Alterations

Metastatic Solid Tumor | Locally Advanced Solid Tumor

United States
Beijing InnoCare Pharma Tech Co., Ltd.

Recruiting

A Phase 2 Study of ICP-723 in Patients With Advanced Solid Tumors or Primary Central Nervous System Tumors

Advanced Solid Tumors Harboring NTRK Fusion | Primary Central Nervous System Tumors Harboring NTRK Fusion

China
Princess Maxima Center for Pediatric Oncology
UMC Utrecht; Dutch Cancer Society

Recruiting

Central Line-associated Bloodstream Infection Prevention Using TauroLock-Hep100 in Pediatric Oncology Patients. (CATERPILLAR)

Central Line-associated Bloodstream Infection (CLABSI)

Netherlands
Queen's University
AFP Innovation Fund

Recruiting

Structural Mitral Valve Project

Mitral Regurgitation

Canada
Adacyte Therapeutics SL

Recruiting

National GMA Post-market Clinical Follow-up Study (GRACE) (GRACE)

Crohn Disease | Ulcerative Colitis

Spain
Fondazione GISE Onlus
University of Padova; Abbott

Recruiting

GISE Registry of Transcatheter Treatment of Mitral Valve Regurgitation With the MitraClip G4

Mitral Valve Regurgitation

Italy
Adacyte Therapeutics SL
Adknoma Health Research

Recruiting

CT to Assess the Efficacy and Safety of Adding GMA to Infliximab in Paediatric Patients With Steroid-refractory Ulcerative Colitis

Ulcerative Colitis

Spain, Portugal
Erasmus Medical Center

Recruiting

Bilateral Prophylactic Mastectomy; Should we Preserve the Pectoral Fascia? (PROFAS)

Seroma | BRCA1/2 Mutation | Bilateral Prophylactic Mastectomy | Pectoral Fascia

Netherlands
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Recruiting

Met Non Small Cell Cancer Registry (MOMENT)

Cancer

United States, Israel, Spain, Finland, France, Belgium, Netherlands, United Kingdom, Canada, Italy, Germany, Sweden, Austria, Czechia, Portugal
Rabin Medical Center

Recruiting

Change in LVEF Following Transcatheter Mitral Edge-To-Edge Repair (MITRA-EF)

Mitral Regurgitation

Israel
Betta Pharmaceuticals Co., Ltd.

Recruiting

A Phase 1 Study of BPI-28592 in Subjects With Advanced Solid Tumors

Metastasis, Neoplasm

China
PETHEMA Foundation
GlaxoSmithKline

Recruiting

Retrospective Study of the Use of Belantamab Mafodotin (Blenrep®) in Patients With Relapsed and/or Refractory Multiple Myeloma (RRMM) in Spain.

RELAPSED AND/OR REFRACTORY MULTIPLE MYELOMA

Spain
Ottawa Heart Institute Research Corporation

Recruiting

Transcatheter Mitral Valve Repair for Inotrope Dependent Cardiogenic Shock (MINOS)

Mitral Regurgitation | Cardiogenic Shock

United States, Canada
Azienda Socio Sanitaria Territoriale degli Spedali...

Recruiting

Mitral Regurgitation Treatment in Advanced Heart Failure (MITRADVANCE)

Heart Failure | Mitral Regurgitation

Italy
Fochon Pharmaceuticals, Ltd.

Recruiting

Study of FCN-098 in Patients With Advanced Solid Tumor

Solid Tumor

China
Ramsay Générale de Santé
European Clinical Trial Experts Network

Recruiting

Hemodynamic Estimation of the Result of the MitraClip Technique: Interest of the Ratio of Mean Arterial Pressure (MAP) to Pressure of the Mean Left Atrium (POG) (MitraPOG) (MitraPOG)

Mitral Insufficiency | Mitraclip

France
GCS Ramsay Santé pour l'Enseignement et la Recherche

Not yet recruiting

Evaluation of the Incidence of NTRK Gene Fusion in Adult Brain Tumours (NTRK Fusion)

Glioma

France
Xuanzhu Biopharmaceutical Co., Ltd.

Recruiting

A Study of XZP-5955 Tablets in Patients With NTRK or ROS1 Fusion Positive Locally Advanced or Metastatic Solid Tumors

Locally Advanced or Metastatic Solid Tumors | Locally Advanced or Metastatic Non-small Cell Lung Cancer

China
Bayer

Recruiting

NTRK Gene Fusion - Positive Advanced or Recurrent Solid Tumors, a Rare Cancer Caused by Specific Changes in the Genes

Advanced or Recurrent Solid Tumor Harboring an NTRK Gene Fusion

Japan
Centre Leon Berard

Recruiting

Real Word European Registry of NTRK Fusions and Other Rare Actionable Fusions (TRacKING) (TRacKING)

Cancer | Cancer Metastatic | ALK Fusion Protein Expression | FGFR2 Gene Translocation | FGFR3 Gene Translocation | NTRK Family Gene Mutation | Gene Fusion | ROS1 Gene Translocation | NTRK Gene Fusion Overexpression | ATIC-ALK Fusion Protein Expression | BCR-FGFR1 Fusion Protein Expression | COL1A1-PDGFB Fusion... and other conditions

France, Denmark, Netherlands, Austria, Germany, Italy, United Kingdom, Czechia, Poland, Slovenia, Spain
Insel Gruppe AG, University Hospital Bern
University Hospital, Basel, Switzerland; Cardiocentro Ticino; Triemli Hospital

Recruiting

Prediction of Reverse Remodeling and Outcome in Patients With Severe Secondary Mitral Valve Regurgitation Undergoing Transcatheter Edge-to-edge Mitral Valve Repair (PRE-MITRA)

Severe Mitral Regurgitation

Switzerland
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Larotrectinib for the Treatment of NTRK Amplification Positive, Locally Advanced or Metastatic Solid Tumors

Locally Advanced Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States
samir kapadia
V-Wave Ltd

Recruiting

Implantation of a Permanent Interatrial Shunt to Reduce Left Atrial Filling Pressures Following MitraClip

Heart Failure | Mitral Regurgitation

United States
Fochon Pharmaceuticals, Ltd.

Recruiting

Study of FCN-011 in Patients With Advanced Solid Tumor（Phase I）and NTRK Fusion Positive Advanced Solid Tumor （Phase II）

Advanced Solid Tumor

China
Jiangsu Simcere Pharmaceutical Co., Ltd.

Recruiting

An Open Label, Multi-center, Phase I Clinical Study to Evaluate the Safety, Effectiveness and Pharmacokinetic Characteristics of SIM1803-1A in Patients With Locally Advanced/Metastatic Solid Tumors With NTRK, ROS1 or ALK Gene Fusion Mutations.

Advanced or Metastatic Solid Tumors With NTRK, ROS1 or ALK Gene Fusion

China
Hospital Clínico Universitario de Valladolid
Hospital Clinic of Barcelona; Hospital de Basurto; Complejo Hospitalario de Navarra and other collaborators

Recruiting

Peri-Implant and Peri-Prosthetic Fractures: Epidemiology, Morbidity, Mortality, Treatment and Outcome Analysis (PIPPAS)

Periprosthetic Fractures | Periprosthetic Fracture of the Upper or Lower Limb | Peri-implant Fracture of the Upper or Lower Limb | Peri-implant Fracture

Spain
Nationwide Children's Hospital

Recruiting

A Pilot Study of Larotrectinib for Newly-Diagnosed High-Grade Glioma With NTRK Fusion

High Grade Glioma | Diffuse Intrinsic Pontine Glioma

United States, Australia, Canada, Germany
AnHeart Therapeutics Inc.

Recruiting

Basket Study of AB-106 for the Treatment of Patients With Solid Tumors With NTRK Fusion Gene

Solid Tumor

China
German Breast Group
Gilead Sciences; ETOP IBCSG Partners Foundation; UNICANCER; Austrian Breast & Colorectal... and other collaborators

Recruiting

Sacituzumab Govitecan in Primary HER2-negative Breast Cancer (SASCIA)

Triple Negative Breast Cancer | HER2-negative Breast Cancer

Spain, France, Germany, Austria, Belgium, Ireland, Italy, Switzerland
Peking University
Hangzhou DIAN Medical Diagnostic Center Co., Ltd., China

Recruiting

Targeted Agent Evaluation in Digestive Cancers in China Based on Molecular Characteristics (VISIONARY)

Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Gastrointestinal Stromal Tumors | Neuroendocrine Tumors | Esophageal Squamous Cell Carcinoma | Biliary Tract Neoplasms | Unknown Primary Cancer | Digestive Cancer

China
Mayo Clinic

Recruiting

Watchman for Patients With Atrial Fibrillation Undergoing Transcatheter Mitral Valve Repair (WATCH-TMVR) (WATCH-TMVR)

Nonvalvular Atrial Fibrillation | Severe Degenerative Mitral Regurgitation

United States, Canada
Charite University, Berlin, Germany
Berlin Institute of Health

Recruiting

TransCranial Doppler for REDUCtion of Silent strokE During MitraClip Implantation (TCD-REDUCE)

Mitral Valve Insufficiency

Germany
Abbott Medical Devices

Recruiting

MitraClip REPAIR MR Study

Mitral Valve Regurgitation

Canada, United States, Switzerland, Germany
Bayer

Recruiting

Study to Learn More About the Safety and Effectiveness of the Drug VITRAKVI During Routine Use in Patients With TRK Fusion Cancer Which is Locally Advanced or Spread From the Place Where it Started to Other Places in the Body (ON-TRK)

Locally Advanced or Metastatic Solid Tumor Harboring an NTRK Gene Fusion

United States, Austria, Denmark, Germany, Italy, Norway, Spain, United Kingdom, Brazil, Russian Federation, Switzerland, Taiwan, Canada, China, Australia, Greece, Belgium, Sweden, Korea, Republic of, France, Argentina, Finland, Ireland and more
Turning Point Therapeutics, Inc.

Recruiting

A Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 Alterations

Lymphoma | Locally Advanced Solid Tumors | Metastatic Solid Tumors | Primary CNS Tumors

United States, Korea, Republic of, Spain, Singapore, Taiwan, Australia, Italy, Canada, France, Denmark, United Kingdom
Technische Universität Dresden
Zentrum für Klinische Studien Leipzig; University Medical Center Mainz; KKS Dresden

Recruiting

Treatment of Concomitant Mitral Regurgitation by Mitral Valve Clipping in Patients With Successful Transcatheter Aortic Valve Implantation. (MITAVI)

Aortic Stenosis | Mitral Regurgitation

Germany
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI); Eli Lilly and Company; Genentech, Inc.; Kazia... and other collaborators

Recruiting

Genetic Testing in Guiding Treatment for Patients With Brain Metastases

Metastatic Malignant Solid Neoplasm | Metastatic Malignant Neoplasm in the Brain | NTRK Family Gene Mutation | CDK Gene Mutation | PI3K Gene Mutation | ROS1 Gene Mutation | KRAS G12C Mutation

United States
Edwards Lifesciences

Recruiting

Edwards PASCAL CLASP IID/IIF Pivotal Clinical Trial (CLASP IID/IIF)

Mitral Regurgitation | Mitral Insufficiency | Functional Mitral Regurgitation | Degenerative Mitral Valve Disease

United States, Canada, Switzerland, Germany
VM Oncology, LLC

Recruiting

Selective TrkA Inhibitor VMD-928 to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma

Sarcoma | Cervical Cancer | Breast Cancer | Adenoid Cystic Carcinoma | Pancreatic Cancer | Esophageal Cancer | Ovarian Cancer | Non-Small Cell Lung Cancer | Thymic Carcinoma | Lung Cancer | Mesothelioma | Bladder Cancer | Head and Neck Carcinoma | Uterine Cancer | Any Solid Tumors Progressed After a Prior Immunotherapy

United States, Puerto Rico
Abbott Medical Devices

Recruiting

Clinical Trial to Evaluate the Safety and Effectiveness of Using the Tendyne Transcatheter Mitral Valve System for the Treatment of Symptomatic Mitral Regurgitation (SUMMIT)

Cardiovascular Diseases | Heart Valve Diseases | Mitral Regurgitation | Mitral Valve Insufficiency | Valve Disease, Heart | Mitral Insufficiency | Functional Mitral Regurgitation | Degenerative Mitral Valve Disease

United States, Canada

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