Search clinical trials for: Multidisciplinary, multicentre prospective study

Total 121791 results

Cancer Institute and Hospital, Chinese Academy...

Not yet recruiting

A Multicentre Prospective Cohort Study: Intensive Adjuvant Therapy for TNBC With BRCA Gene Mutation

Early-stage Triple-negative Breast Cancer With BRCA1/2 Mutations

China
Cancer Institute and Hospital, Chinese Academy...

Not yet recruiting

A Multicentre Prospective Cohort Study: Effect of (Neo)Adjuvant Therapy on Lipids in Young Breast Cancer Patients

Lipids | Young Breast Cancer Patient | Anti-tumour Drug Therapy
University Health Network, Toronto
Queen's University

Not yet recruiting

Albumin Utilization in Adult Cardiac Surgical Patients : A Multicentre Prospective Cohort Study (AlbACS-1Pro)

Antithrombin III Levels | Albumin Levels

Canada
B.Braun Avitum AG

Recruiting

Prospective, Multicentre, Randomized, Controlled, Cross-over Study on the Safety and Performance of the Biologic Fusion Option of DialogiQ Compared to Haemodialysis Without Biologic Fusion in Hypotension Prone Patients on Maintenance Haemodialysis

Renal Dialysis

Italy
University Hospitals of North Midlands NHS Trust

Not yet recruiting

Prospective, Multicentre Study to Validate the GastroIntestinal Dysfunction Score (GIDS) and Describe Prevalence, Outcomes, and Management of Phosphate Disorders in Intensive Care Patients (GUTPHOS)

Gastrointestinal Dysfunction

United Kingdom
Meyer Children's Hospital IRCCS

Recruiting

Multicentre Prospective Observational Study of Acute Intoxications in Paediatric Age

Acute Intoxication

Italy
Charles University, Czech Republic

Recruiting

Prospective Multicentre Study on Symptoms in First-onset Bronchial Asthma in Children and Adolescents

Pneumonia | Cough | Asthma | Asthma in Children | Dyspnea | Recurrent Respiratory Tract Infections | Shortness of Breath | Wheezing | Mucus; Plug | Lower Respiratory Tract and Lung Infections | Chest Tightness

Czechia
Italfarmaco

Recruiting

A Multicentre, Prospective, Open-label, Non-comparative Study

Contraception

Italy
Centre Hospitalier Universitaire de Saint Etienne

Recruiting

Performance of Spectral CT-scan in Patients With Metastatic Colorectal Cancer: a Prospective Multicentre Study

Colo-rectal Cancer

France
Foundation for Innovative New Diagnostics, Switzerland

Not yet recruiting

Evaluating Next Generation LAM Assays and Molecular Diagnostics (POC and Near POC) for the Diagnosis of TB Among People With Presumptive TB: a Prospective Multicentre Diagnostic Accuracy Study (DriveDx4TB)

Tuberculosis
Guangdong Provincial People's Hospital
Shenzhen People's Hospital; Affiliated Cancer Hospital of Shantou University... and other collaborators

Not yet recruiting

Dynamic Follow-up of Symptoms Based on Patient-reported Outcomes in Immunotherapy for Esophageal Cancer: a Prospective Multicentre Cohort Study (SPRING)

Esophageal Cancer | Immunotherapy | Patient-reported Outcomes

China
Johann Wolfgang Goethe University Hospital

Recruiting

Recycling Potential in Endoscopy - a Multicentre Prospective Observational Study

Sustainable Development

Germany
iVascular S.L.U.

Recruiting

Prospective, Multicentre Study to Evaluate the Thrombectomy System for Stroke: INEDIT, INDEEP and INTERCEPT (SEMTiC)

Acute Ischemic Stroke

Spain, Belgium, France, Germany
Vinodh Kakkassery, MD
University Hospital Tuebingen; University Hospital Schleswig-Holstein

Not yet recruiting

Multicentre Implementation and Validation of a Molecular Diagnostic for VitreoRetinal Lymphoma (DecodeVRL)

Vitreoretinal Lymphoma
Fondation Lenval

Recruiting

A Multicentre French Prospective Study of Children With Food Protein Induced Enterocolitis Syndrome in Its Acute Form (SEIPA-FPIES)

Food Protein Induced Enterocolitis Syndrome (FPIES)

France
The First Affiliated Hospital of Zhengzhou University

Not yet recruiting

Esophageal Arterial Infusion Chemotherapy Versus Systemic Intravenous Chemotherapy for Resectable Locally Advanced Esophageal Squamous Cell Carcinoma: a Prospective, Multicentre, Randomised Controlled Clinical Study

Resectable Locally Advanced Esophageal Squamous Cell Carcinoma
SerenaGroup, Inc.
Dabir Surfaces Inc

Recruiting

A Multicentre Prospective Study Evaluating an Off-loading Mattress Overlay System in Healing of Stage 3 Pressure Ulcers (DABIRPrU)

Pressure Ulcer

United States
Sebastiano Biondo

Recruiting

Prospective and Multicentre Study on Clinical-biological Factors Predictive of Chronic Colon DIverticulitis (DICRO)

Acute Diverticulitis

Spain
Imperial College London
Joint Replacement Instrumented Orthopaedics Ltd

Recruiting

Furlong Evolution® Hip Trial

Focus: A Multicentre Prospective Clinical Surveillance Study Aims to Assess the Clinical, Functional and Radiological Outcome of the Furlong Evolution® Hip Stem

United Kingdom
Zhujiang Hospital

Enrolling by invitation

Haemodynamic Mechanisms and Multicentre Prospective Cohort Study of the Pipeline Flow-diverting Device for the Treatment of Intracranial Aneurysms. Evaluation of the Safety and Efficacy of the Pipeline Flow-diverting Device for the Treatment of Intracranial Aneurysms

Safety Issues

China
Zimmer Biomet
Zimmer, GmbH

Active, not recruiting

Sidus(TM) Post Market Clinical Follow-up (PMCF) Study

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Non-inflammatory Degenerative Joint Disease (NIDJD) | Inflammatory Joint Disease (IJD)

Germany, Austria, Italy, France, United Kingdom
Centre hospitalier de l'Université de Montréal...
UCB Pharma

Completed

Brivaracetam: a Prospective and Multicentre Post-marketing Observational Study

Epilepsy

Canada
Boehringer Ingelheim

Completed

A Prospective, Randomised, Double-blind, Double-dummy, Forced-titration, Multicentre, Parallel Group, One Year Treatment Trial to Compare Telmisartan (MICARDIS) 80 mg Versus Losartan (COZAAR) 100 mg, in Hypertensive Type 2 Diabetic Patients With Overt Nephropathy (AMADEO Study)

Hypertension | Diabetic Nephropathies

Taiwan, United States, Canada, Thailand, Korea, Republic of, Argentina, Australia, Brazil, Mexico, New Zealand
Fondazione Melanoma Onlus

Withdrawn

"Dabrafenib and Trametinib in Circulating Free DNA BRAFV600 Mutated Metastatic Melanoma Patients: a Prospective Phase II, Open Label, Multicentre Study - (Bioliquid TAILOR Study - BIOTAILOR)"

Melanoma

Italy
Centre Leon Berard

Completed

Prospective Multicentre Study of the Use of Ketamine in the Treatment of Refractory Chronic Pain in the French CLCC (KETACANCER)

Cancer | Chronic Pain | Neuropathic Pain | Opioid Use

France
Zimmer Biomet

Active, not recruiting

Multicentre Prospective Study to Evaluate Long-term Clinical Outcomes of the Sirius Cemented Femoral Stem (Sirius)

Arthroplasty, Replacement, Hip

Denmark, United Kingdom
Fundación EPIC

Active, not recruiting

A Prospective Study, Single-arm, Multicentre, Observational to Evaluate Safety and Effectiveness of Stent Ultimaster Tansei Coronary Stent in Complex Coronary Lesions. (TANSEI)

Coronary Artery Disease | Ischemic Heart Disease

Spain
Centre Hospitalier Universitaire, Amiens
Centre Hospitalier Universitaire de Caen; Centre Hospitalier VALENCIENNES; st...

Completed

Individualized Hemodynamic Optimization by Indirect Measurement of the Respiratory Quotient in Major Surgery: Prospective Randomized Multicentre Open-Label Study (OPHIQUE) Individualized Optimization by Indirect Measurement of the Respiratory Quotient (OPHIQUE)

Respiratory Complication | Post-Op Complication

France
Zagazig University

Completed

A Prospective Multicentre Study Evaluating the Outcomes of the Abdominal Wall Dehiscence Repair Using Posterior Component Separation With Transversus Abdominis Muscle Release Reinforced by a Retro-muscular Mesh - Filling a Step

Abdominal Wall Defect

Egypt
Cambridge University Hospitals NHS Foundation Trust
Sheffield Teaching Hospitals NHS Foundation Trust; University Hospital Birmingham... and other collaborators

Completed

A Prospective UK Multicentre Study of Kidney Donors (EARNEST)

Living Kidney Donors

United Kingdom
University Hospital, Bordeaux

Completed

Multicentre Prospective Cohort Study of Patients With Chronic Alcoholic and/or Metabolic Liver Disease (CALMET)

Metabolic Diseases | Liver Diseases, Alcoholic

France
University Paul Sabatier of Toulouse

Completed

Outcomes of FEVAR and BEVAR to Treat Secondary Type 1 Endoleak After EVAR: A Prospective Multicentre Study

Abdominal Aortic Aneurysm
Drugs for Neglected Diseases

Completed

Efficacy and Safety of Fexinidazole in Children at Least 6 Years Old and Weighing Over 20 kg With Human African Trypanosomiasis (HAT) Due to T.b. Gambiense: a Prospective, Multicentre, Open Study, plug-in to the Pivotal Study

Human African Trypanosomiasis (HAT)

Congo, The Democratic Republic of the
Drugs for Neglected Diseases

Completed

Efficacy and Safety of Fexinidazole in Patients With Stage 1 or Early Stage 2 Human African Trypanosomiasis (HAT) Due to T.b. Gambiense: a Prospective, Multicentre, Open-label Cohort Study, plug-in to the Pivotal Study

Human African Trypanosomiasis (HAT)

Congo, The Democratic Republic of the
Royal Victoria Hospital, Canada

Completed

Impact of a Regional Antimicrobial Stewardship on the Length of Stay of Patients Admitted to Hospital With Pneumonia (RASPCAP)

Pneumonia

Canada
Centro Nacional de Investigaciones Oncologicas...
Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina... and other collaborators

Completed

Prospective Multicentre Cohort Study PROREPAIR-B (mCRPC)

Prostate Cancer
University of Southampton
Assistance Publique - Hôpitaux de Paris; Hacettepe University; Universitaire... and other collaborators

Unknown

PRospective Observational Multicentre Study on VAriability of Lung Function in Stable PCD Patients (PROVALF-PCD)

Primary Ciliary Dyskinesia

United Kingdom
Assistance Publique Hopitaux De Marseille

Unknown

The Evaluation of the Diagnostic Properties of Intra-operative In-situ Thyroglobin Levels of Cervical Lymph Nodes, in the Discrimination Between Benign and Malignant Lymph Nodes in Thyroid Cancer: a Prospective Multicentre Study. (Tgcyto)

Thyroid Cancer

France
Association for Innovation and Biomedical Research...
European Vision Institute Clinical Research Network

Completed

Prospective, Randomized, Multicentre, Open-label, Phase II / III Study to Assess Efficacy and Safety of Ranibizumab 0.5 mg Intravitreal Injections Plus Panretinal Photocoagulation (PRP) Versus PRP in Monotherapy in the Treatment of Subjects With High Risk Proliferative Diabetic Retinopathy. (PROTEUS)

High Risk Proliferative Diabetic Retinopathy

Portugal, Italy, United Kingdom, France
Mycenax Biotech Inc.

Unknown

A Prospective, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicentre, Phase III Study to Evaluate the Efficacy and Safety of ENIA11 in Combination With DMARDs Versus DMARDs Alone in Patients With Rheumatoid Arthritis

Combination With DMARDs

Taiwan
Trans Tasman Radiation Oncology Group
Peter MacCallum Cancer Centre, Australia

Completed

Magnetic Resonance Imaging (MRI) Staging of Cervix Cancer

Cancer of the Uterine Cervix

United States, Singapore, Australia, New Zealand, India
Novartis Pharmaceuticals

Terminated

A Prospective, Observational, Multicentre, 2 Year Study Evaluating the Use of Eylea (Aflibercept) for the Treatment of Neovascular (Wet) Age-related Macular Degeneration in UK NHS Opthalmology Clinics

Wet Age-related Macular Degeneration

United Kingdom
National University, Singapore
Boston Scientific Corporation

Completed

Sleep and Stent Study: a Multicentre, Prospective Study

Obstructive Sleep Apnea

Singapore
University Hospital, Bordeaux

Completed

Lenalidomide in Relapsed or Refractory Primary-cutaneous Large B-cell Lymphoma Leg-type : Multicentre Prospective Phase II Single Arm Trial of the French Study Group of Cutaneous Lymphoma (REV-LEG)

Refractory Primary-cutaneous Large B-cell Lymphoma (Leg-type)

France
Countess of Chester NHS Foundation Trust

Unknown

Hartmann's Versus Intersphincetric APE: A Prospective, Multicentre Study (HiP)

Rectal Cancer

United Kingdom
Peking Union Medical College Hospital
Jiangsu HengRui Medicine Co., Ltd.

Unknown

An Open Label, Prospective, Multicentre, Non-interventional Study of Apatinib for Chemotherapy-Refractory Advanced Metastatic Gastric Cancer (AHEAD-G202)

Metastatic Gastric Cancer

China
University Hospital, Lille
Ministry of Health, France

Completed

Development of a Modified Pediatric Early Warning Score: a French Prospective Multicentre Regional Study

Critical Illness

France
LEO Pharma
Quintiles, Inc.

Completed

LEO 90105 Ointment in Japanese Subjects With Psoriasis

Psoriasis

Japan
Orion Corporation, Orion Pharma

Completed

Prospective Multicentre Non-interventional Study of VANTAS® for the Treatment of Patients With Advanced Prostate Cancer (Vantas)

Prostate Cancer

Sweden
Institut National de la Santé Et de la Recherche...
Centers for Disease Control and Prevention; Ministry of Health, Mozambique; War... and other collaborators

Unknown

Infective Endocarditis in Developing Countries, a Prospective, Observational, Multicentre Study (EndoDev)

Infective Endocarditis

Fiji, Lao People's Democratic Republic, Mozambique, Senegal, Uganda

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