Search clinical trials for: Natural Killer cells

Total 14278 results

Anhui Provincial Cancer Hospital
Anhui Kecheng intelligent health technology Co., LTD

Recruiting

Safety and Efficacy of Intraperitoneal Injection of METR-NK Cells as Neoadjuvant Therapy for Advanced Epithelial Ovarian Cancer

Ovarian Cancer

China
Beijing Tongren Hospital

Recruiting

Linperlisib Combined With Camrelizumab and Pegaspargase in Advanced or Relapsed/Refractory NK/T-cell Lymphoma

T-lymphoblastic Lymphoma | Natural Killer/T-Cell Lymphoma, Nasal and Nasal-Type

China
Zhejiang University
Hangzhou Qihanjiyin Biotech Co.,Ltd.

Recruiting

Natural Killer(NK) Cell Therapy Targeting CLL1 or CD33 in Acute Myeloid Leukemia

AML, Adult

China
Senti Biosciences

Recruiting

SENTI-202: Off-the-shelf Logic Gated CAR NK Cell Therapy in Adults With CD33 and/or FLT3 Blood Cancers Including AML/MDS

AML/MDS | CD33 Expressing Hematological Malignancies | FLT3 Expressing Hematological Malignancies

United States, Australia
Dana-Farber Cancer Institute
ImmunityBio, Inc.

Not yet recruiting

Intraperitoneal Cytokine-Induced Memory Like (CIML) Natural Killer (NK) Cells in Recurrent Ovarian Cancer

Ovarian Cancer | Platinum-resistant Ovarian Cancer | Ovarian Carcinoma | Recurrent Ovary Cancer | Ovarian Carcinoma, Recurrent

United States
Dana-Farber Cancer Institute
ImmunityBio, Inc.; Kidney Cancer Association

Not yet recruiting

A Phase 0 Pilot Study of Memory-like Natural Killer (NK) Cell Immune Therapy in Combination With N-803 in Patients With Renal Cell Carcinoma or Urothelial Carcinoma

Renal Cell Carcinoma | Urothelial Carcinoma | Renal Carcinoma

United States
Fudan University

Recruiting

Screening Study of Combined Sequential Chemotherapy and Radiation Therapy for Early-stage NK/T-cell Lymphoma

Natural Killer/T-Cell Lymphoma, Nasal and Nasal-Type

China
Ruijin Hospital

Not yet recruiting

The Efficacy and Safety of Chidamide, Anti-PD-1 Antibody in Combination With Pegaspargase Versus DDGP in the Treatment of Newly Diagnosed, Stage III to IV Extranodal Natural Killer/T-Cell Lymphoma

Extranodal Natural Killer T Cell Lymphoma

China
Washington University School of Medicine
The Leukemia and Lymphoma Society; Rising Tide Foundation; St. Louis Children...

Not yet recruiting

Pilot Study of Memory-like Natural Killer (ML NK) Cells After TCRαβ T Cell Depleted Haploidentical Transplant in AML (ABCD-NK)

Acute Myeloid Leukemia | Aml | AML, Childhood | Acute Myeloid Leukemia, Pediatric

United States
Dushu Lake Hospital Affiliated to Soochow University

Recruiting

Natural Killer (NK) Cells (XS005) Injection Combined With Stupp Regimen for Adjuvant Chemotherapy in Subjects With Primary Glioblastoma(GBM)

Glioblastoma | GBM

China
Dana-Farber Cancer Institute

Recruiting

Preemptive CIML NK Cell Therapy After Hematopoietic Stem Cell Transplantation

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Leukemia | Leukemia, Myeloid | Myeloproliferative Disorders | Myeloproliferative Neoplasm

United States
ImmunityBio, Inc.

Recruiting

Single Center Study Of N-803 Stimulation On Expansion, Enrichment, Proliferation Of Natural Killer Cells Collected By Apheresis

Healthy Subjects

United States
Margaret Gatti-Mays

Recruiting

Gemcitabine and Ex Vivo Expanded Allogenic Universal Donor, TGFβi Natural Killer (NK) Cells With or Without Naxitamab (Danyelza) for the Treatment of Patients With Metastatic, GD2 Expressing, HER2 Negative Breast Cancer

Anatomic Stage IV Breast Cancer AJCC v8 | HER2-Negative Breast Carcinoma

United States
Institut National de la Santé Et de la Recherche...

Recruiting

Characterization of Natural Killer Cells in Severe Asthma Patients in Comparison With Control Subjects (NKAS)

Asthma Acute

France
Radboud University Medical Center
Maastricht University Medical Center

Recruiting

Aerobe Cycling Training in Women With Unexplained Recurrent Pregnancy Loss (HMOVE)

Recurrent Pregnancy Loss

Netherlands
Zhejiang University

Recruiting

Universal Dual-target NKG2D-NKp44 CAR-T Cells in Advanced Solid Tumors

Advanced Solid Tumors

China
Antonio Pérez Martínez

Recruiting

Clinical Trial of Infusion of Activated NK Cells for the Treatment of Sarcomas (SANKOMA)

Malignant Sarcoma

Spain
Sabine Mueller, MD, PhD
Washington University School of Medicine; Nationwide Children's Hospital; Rally...

Not yet recruiting

Intra-Tumoral Injections of Natural Killer Cells for Recurrent Malignant Brain Tumors (PNOC028)

Pediatric Brain Tumor | Recurrent Pediatric Brain Tumor | Pediatric Supratentorial Neoplasm

United States
GI Cell, Inc.

Recruiting

A Study of GIC-102 (Allogeneic Natural Killer Cells) in Patients With Advanced Solid Tumors, Non-Hodgkin Lymphoma, and Multiple Myeloma

Advanced Solid Tumors | Relapsed/Refractory Multiple Myeloma | Relapsed/Refractory Non-Hodgkin Lymphoma

Korea, Republic of
University Hospital, Tours
Research Center for Respiratory Diseases, Inserm U1100

Recruiting

Study of Neonatal IgG Fc Receptor Expression in Natural Killer T Cells Expressing an Invariant T Receptor : Implication in the Pathophysiology of Systemic Lupus (FiNKLUPUS)

Systemic Lupus Erythematosus | Physiopathology

France
Washington University School of Medicine

Not yet recruiting

Memory-Like Natural Killer Cells With Nivolumab and Relatlimab in Advanced or Metastatic Melanoma After Progression on Checkpoint Inhibitors

Metastatic Melanoma | Advanced Melanoma

United States
Kari Kendra

Recruiting

Natural Killer Cell Therapy (UD TGFbetai NK Cells) and Temozolomide for the Treatment of Stage IV Melanoma Metastatic to the Brain

Metastatic Melanoma | Clinical Stage IV Cutaneous Melanoma AJCC v8 | Pathologic Stage IV Cutaneous Melanoma AJCC v8 | Metastatic Malignant Neoplasm in the Brain

United States
Children's Hospital Medical Center, Cincinnati

Recruiting

Cytokine-Induced Memory-Like Natural Killer Cells (CIML-NK) for Relapsed & Refractory Acute Myeloid Leukemia (AML)

Acute Myeloid Leukemia

United States
Nationwide Children's Hospital

Recruiting

Safety and Efficacy of Expanded, Universal Donor Natural Killer Cells for Relapsed/Refractory AML (KARMA)

Acute Myeloid Leukemia

United States
Sun Yat-sen University

Recruiting

Tislelizumab Combined With Mitoxantrone Hydrochloride Liposome in Extranodal Natural Killer/T Cell Lymphoma

Extranodal Natural Killer T Cell Lymphoma

China
University of Mississippi Medical Center
National Center for Complementary and Integrative Health (NCCIH)

Recruiting

Spirulina Oral Supplement for Enhancing Host Resilience to Virus Infection

Healthy Volunteers

United States
Jennifer Eva Selfridge

Recruiting

Natural Killer (NK) Cells in Combination With Interleukin-2 (IL-2) and Transforming Growth Factor Beta (TGFbeta) Receptor I Inhibitor Vactosertib in Cancer

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Colorectal Cancer | Hodgkin Lymphoma | Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | Non Hodgkin Lymphoma | Chronic Myeloid Leukemia | Plasma Cell Myeloma | Hematologic Malignancy | Rectum Cancer | Myeloproliferative Syndrome

United States
Vall d'Hebron Institute of Oncology
Hospital del Mar; Clinica Universidad de Navarra, Universidad de Navarra; Puerta... and other collaborators

Recruiting

A Study of Allogenic Natural Killer Cells in Combination With Trastuzumab and Pertuzumab in Adult Patients With Refractory Metastatic Her2 Positive Breast Cancer. NK-ACT-BC_2020

Breast Neoplasms

Spain
Zhejiang University
Hangzhou Qihan Biotech Co.,Ltd.

Recruiting

Natural Killer (NK) Cell Therapy for B-Cell Malignancies

B-cell Lymphoma | B-cell Acute Lymphoblastic Leukemia

China
The First Affiliated Hospital with Nanjing Medical...
Zhenjiang First People's Hospital; Second Affiliated Hospital of Soochow University and other collaborators

Not yet recruiting

A Clinical Study of the Value of Circulating Free Methylated EBV DNA in Extranodal NK/T Cell Lymphoma

Extranodal Natural Killer/T-cell Lymphoma

China
First Affiliated Hospital Xi'an Jiaotong University

Recruiting

Donor Immune Cell Therapy for Acute Myeloid Leukemia

Acute Myeloid Leukemia

China
City of Hope Medical Center
National Cancer Institute (NCI); CytoImmune Therapeutics

Recruiting

Genetically Engineered Natural Killer (NK) Cells With or Without Atezolizumab for the Treatment of Non-small Cell Lung Cancer Previously Treated With PD-1 and/or PD-L1 Immune Checkpoint Inhibitors

Metastatic Lung Non-Small Cell Carcinoma | Refractory Lung Non-Small Cell Carcinoma | Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Stage III Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Stage IIIA Lung Cancer AJCC v8 | Stage IIIB Lung Cancer AJCC v8 | Stage IIIC Lung Cancer... and other conditions

United States
Belarusian Research Center for Pediatric Oncology...

Recruiting

Expanded Haploidentical Natural Killer Cells as Consolidation Strategy for Children/Young Adults With AML

Acute Myeloid Leukemia

Belarus
German Cancer Research Center

Not yet recruiting

Natural Killer Cell Immunotherapy in Combination With PARP-inhibition in Acute Myeloid Leukemia (NAKIP-AML)

Acute Myeloid Leukemia
Instituto de Investigación Hospital Universitario...

Recruiting

"Phase I / II Study on Infusion of Natural Killer Cells After Haploidentical Transplantation in Pediatric Patients" (PHINK)

High-risk Leukemias

Spain
Belarusian Research Center for Pediatric Oncology...

Recruiting

Immunotherapy With ex Vivo Expanded Haploidentical Natural Killer Cells for Children/Young Adults With AML

Acute Myeloid Leukemia

Belarus
Universitair Ziekenhuis Brussel

Recruiting

The Role of Natural Killer, Complement and T-lymphocytes in COVID-19 Disease, a Prospective Monocentric Study (TONIC)

Covid19 | Peripheral Blood Mononuclear Cells | Complement Abnormality

Belgium
The Third Affiliated Hospital of Guangzhou Medical...
Hangzhou Cheetah Cell Therapeutics Co., Ltd

Recruiting

NKG2D CAR-T Cells to Treat Patients With Previously Treated Liver Metastatic Colorectal Cancer

Refractory Metastatic Colorectal Cancer

China
Zhejiang University

Recruiting

NKG2D CAR-NK Cell Therapy in Patients With Refractory Metastatic Colorectal Cancer

Refractory Metastatic Colorectal Cancer

China
Fate Therapeutics

Recruiting

FT576 in Subjects With Multiple Myeloma

Multiple Myeloma | Myeloma

United States
Royan Institute
Tehran University of Medical Sciences

Recruiting

Nk Cell Therapy for Recurrent Glioblastoma Multiform Patients

Recurrent Glioblastoma | Glioblastoma Multiform

Iran, Islamic Republic of
Sohag University

Not yet recruiting

Study of T Cells and Natural Killer Cells Expression in Patients With Immune Thrombocytopenic Purpura

Immune Thrombocytopenic Purpura
Nkarta Inc.

Recruiting

NKX019, Intravenous Allogeneic Chimeric Antigen Receptor Natural Killer Cells (CAR NK), in Adults With B-cell Cancers

Lymphoma, Non-Hodgkin | Waldenstrom Macroglobulinemia | Mantle Cell Lymphoma | Chronic Lymphocytic Leukemia | B-cell Acute Lymphoblastic Leukemia | Small Lymphocytic Lymphoma | Large B-cell Lymphoma | Indolent Lymphoma | Aggressive Lymphoma | Large-cell Lymphoma

United States, Australia
Sun Yat-sen University

Recruiting

Sintilimab in Combination With Chidamide in Newly Diagnosed ENKTCL

Safety and Efficacy

China
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Engineered NK Cells Containing Deleted TGF-BetaR2 and NR3C1 for the Treatment of Recurrent Glioblastoma

Recurrent Gliosarcoma | Recurrent Supratentorial Glioblastoma | Supratentorial Gliosarcoma

United States
NKMAX Co., Ltd.

Recruiting

A Study to Evaluate the Safety and Anti-tumor Activity of SNK01 (NK Cells) Administered in Combination With Chemotherapy or Chemotherapy / Cetuximab in Local Advanced or Metastatic Non-small Cell Lung Cancer Patients Who Failed Tyrosine Kinase Inhibitor Treatment (SNK_ASTER)

Non-small Cell Lung Cancer

Korea, Republic of
Tanta University
Mansoura University; Benha University

Recruiting

Uterine Natural Killer (uNK) Cell Expression in Patients With Repeated ICSI Failures: A Multicenter Cohort Study (UNK)

Repeated Implantation Failure | ICSI Failure | uNatural Killer Cells

Egypt
John Reneau

Recruiting

Third-Party Natural Killer Cells and Mogamulizumab for the Treatment of Relapsed or Refractory Cutaneous T-cell Lymphomas or Adult T-Cell Leukemia/Lymphoma

Recurrent Primary Cutaneous T-Cell Non-Hodgkin Lymphoma | Recurrent Adult T-Cell Leukemia/Lymphoma | Refractory Primary Cutaneous T-Cell Non-Hodgkin Lymphoma | Refractory Adult T-Cell Leukemia/Lymphoma

United States
Won Seog Kim
Sanofi

Recruiting

Study of Isatuximab and Cemiplimab in Relapsed or Refractory Natural Killer/T-cell Lymphoid Malignancy (ICING)

Natural Killer/T-cell Lymphoma | Relapsed Natural Killer/T-cell Lymphoma | Refractory Natural Killer/T-cell Lymphoma

Korea, Republic of
Biohaven Pharmaceuticals, Inc.
Dana-Farber Cancer Institute

Recruiting

Autologous Memory-like NK Cell Therapy With BHV-1100 (Formerly KP1237), Low Dose IL-2 in Multiple Myeloma Patients

Multiple Myeloma

United States

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