Search clinical trials for: Neonatal thymus transplant

Total 17125 results

Fundacion Clinica Valle del Lili

Recruiting

Neonatal Thymus Transplantation in Humans (SUPERTHYM)

Safety Issues

Colombia
Johns Hopkins University

Not yet recruiting

Comparing Single Versus Repeat NMT on the Diversity of the Neonatal Nasal Microbiome

Staphylococcus Aureus | Microbial Colonization | Neonatal Infection

United States
iECURE, Inc.

Recruiting

An Open-label Study to Investigate ECUR-506 in Male Babies Less Than 9 Months of Age With Neonatal Onset OTC Deficiency (OTC-HOPE)

Urea Cycle Disorders, Inborn | Ornithine Transcarbamylase Deficiency | Ornithine Transcarbamylase Deficiency Disease | Ornithine Carbamoyltransferase Deficiency (Disorder)

United Kingdom
David Bond, MD

Recruiting

Tafasitamab and Lenalidomide Followed by Tafasitamab and ICE as Salvage Therapy for Transplant Eligible Patients With Relapsed/ Refractory Large B-Cell Lymphoma

Recurrent Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Refractory Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Recurrent High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements | Refractory High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements | Recurrent... and other conditions

United States
Johns Hopkins University
National Institute of Allergy and Infectious Diseases (NIAID)

Recruiting

Feasibility and Safety Study of Parent-to-Child Nasal Microbiota Transplant (ParentsTREAT)

Staphylococcus Aureus | Microbial Colonization | Neonatal Infection

United States
Children's Oncology Group

Recruiting

Mismatched Related Donor Versus Matched Unrelated Donor Stem Cell Transplantation for Children, Adolescents, and Young Adults With Acute Leukemia or Myelodysplastic Syndrome

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Myelodysplastic Syndrome | Mixed Phenotype Acute Leukemia

United States, Australia, Canada
Institute of Hematology & Blood Diseases Hospital
The Second Hospital of Hebei Medical University; Tianjin Medical University... and other collaborators

Not yet recruiting

Posaconazole for Pulmonary Fungal Infection Prophylaxis in Hematopoietic Stem Cell Transplantation Patients

Pulmonary Fungal Infection

China
Massachusetts General Hospital

Recruiting

Renal Allograft Tolerance Through Mixed Chimerism - SMC/MGH

Renal Failure

United States
Maastricht University Medical Center
Charles University, Czech Republic; Karolinska University Hospital; Hospices... and other collaborators

Recruiting

European/Euro-ELSO Survey on Adult and Neonatal/ Pediatric COVID-19 Patients in ECMO (EuroECMO-COVID)

Septic Shock | Extracorporeal Membrane Oxygenation | COVID | SARS-CoV-2 | Cardiogenic Shock | ARDS, Human | Refractory Hypoxemia

Spain, Germany, Netherlands, France, Sweden, Belgium, Austria, Portugal, Poland, United Kingdom, Italy, Lithuania, Czechia, Denmark, Greece, Hungary, Israel, Russian Federation, Switzerland
Masonic Cancer Center, University of Minnesota

Recruiting

MT2013-31: Allo HCT for Metabolic Disorders and Severe Osteopetrosis

Hurler Syndrome | Sphingolipidoses | Peroxisomal Disorders | Metachromatic Leukodystrophy | Alpha-Mannosidosis | Hunter Syndrome | Mucopolysaccharidosis Disorders | Maroteaux Lamy Syndrome | Sly Syndrome | Fucosidosis | Aspartylglucosaminuria | Glycoprotein Metabolic Disorders | Recessive Leukodystrophies | Globoid... and other conditions

United States
National Cancer Institute (NCI)

Recruiting

Allogeneic Hematopoietic Stem Cell Transplant for GATA2 Mutations

MDS | Immunodeficiency | GATA2

United States
University of Edinburgh
Chief Scientist Office of the Scottish Government

Active, not recruiting

Targeting Investigation and Treatment in Patients With Type 2 Myocardial Infarction (TARGET-Type 2)

Myocardial Infarction Type 2

United Kingdom
Children's Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)

Neuroblastoma | Ganglioneuroblastoma

United States, Canada, Puerto Rico
Xencor, Inc.
ICON Clinical Research

Active, not recruiting

Study to Evaluate Safety and Tolerability of XmAb13676 (Plamotamab) in Patients With CD20-expressing Hematologic Malignancies

Chronic Lymphocytic Leukemia | B-cell Non-Hodgkins Lymphoma

United States, France, Korea, Republic of, United Kingdom
Henrietta Bada
National Institute on Drug Abuse (NIDA)

Active, not recruiting

Non-Opiate Treatment After Prenatal Opiate Exposure to Prevent Postnatal Injury to the Young Brain (No-POPPY)

Neonatal Abstinence Syndrome

United States
Baylor College of Medicine
National Cancer Institute (NCI)

Completed

Dose Adjusted EPOCH-R, to Treat Mature B Cell Malignancies (DA-EPOCH-R)

Diffuse Large B Cell Lymphoma | Post Transplant Lymphoproliferative Disorder | Primary Mediastinal (Thymic) Large B-cell Lymphoma

United States
University of Nebraska

Active, not recruiting

ONC 201 Maintenance Therapy in Acute Myeloid Leukemia and Myelodysplastic Syndrome After Stem Cell Transplant

Acute Myeloid Leukemia | Myelodysplastic Syndromes

United States
Chiesi Farmaceutici S.p.A.

Completed

Cangrelor Neonatal PK/PD and Safety Study

Partial Obstruction of Systemic to Pulmonary Artery Shunt | Complete Obstruction of Systemic to Pulmonary Artery Shunt

United States
Fred Hutchinson Cancer Center
ADC Therapeutics

Withdrawn

Loncastuximab Tesirine in Combination With Chemotherapy Prior to Stem Cell Transplant for the Treatment of Recurrent or Refractory Diffuse Large B-Cell Lymphoma

Recurrent Diffuse Large B-Cell Lymphoma | Recurrent Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Refractory Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Recurrent Diffuse Large B-Cell Lymphoma, Not Otherwise Specified | Recurrent High... and other conditions

United States
Scripps Health

Completed

Nonmyeloablative Allogeneic Transplant (Mini-allo)

Melanoma | Sarcoma | Renal Cell Carcinoma | Breast Cancer | Multiple Myeloma | Hodgkin's Lymphoma | Non-Hodgkin's Lymphoma | Ovarian Cancer | Thymoma | Waldenstrom Macroglobulinemia | Mantle Cell Lymphoma | Chronic Lymphocytic Leukemia | Myelodysplastic Syndrome | Acute Lymphocytic Leukemia | Acute Myelogenous Leukemia | Chronic Myelogenous Leukemia and other conditions

United States
Enzyvant Therapeutics GmBH

Approved for marketing

Expanded Access Protocol Thymus Transplantation

Immunodeficiency | Poor Thymic Function | Athymia | Immunoreconstitution | Thymus Transplantation | Low T Cell Numbers
Enzyvant Therapeutics GmBH
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy... and other collaborators

Approved for marketing

Thymus Transplantation Safety-Efficacy

DiGeorge Syndrome | DiGeorge Anomaly | Complete DiGeorge Anomaly | Complete DiGeorge Syndrome

United States
Enzyvant Therapeutics GmBH
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy... and other collaborators

Completed

Parathyroid and Thymus Transplantation in DiGeorge #931

DiGeorge Syndrome | Hypoparathyroidism | Complete DiGeorge Syndrome

United States
Enzyvant Therapeutics GmBH
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy... and other collaborators

Completed

Thymus Transplantation With Immunosuppression (884)

DiGeorge Syndrome | DiGeorge Anomaly | Complete DiGeorge Anomaly | Complete DiGeorge Syndrome

United States
Enzyvant Therapeutics GmBH

Terminated

Phase I Study of Umbilical Cord Blood Transplantation Followed by Third Party Thymus Transplantation

Stem Cell Transplantation

United States
Enzyvant Therapeutics GmBH
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy... and other collaborators

Terminated

Serum-Free Thymus Transplantation in DiGeorge Anomaly (SerumFree)

DiGeorge Anomaly
Enzyvant Therapeutics GmBH
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy... and other collaborators

Completed

Thymus Transplantation Dose in DiGeorge #932

DiGeorge Syndrome | DiGeorge Anomaly | Complete DiGeorge Anomaly | Complete DiGeorge Syndrome

United States
Enzyvant Therapeutics GmBH
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy... and other collaborators

Completed

Phase I/II Thymus Transplantation With Immunosuppression #950 (#950)

DiGeorge Anomaly | Complete DiGeorge Anomaly | Complete DiGeorge Syndrome | Complete Atypical DiGeorge Anomaly | Complete Atypical DiGeorge Syndrome

United States
Enzyvant Therapeutics GmBH
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy... and other collaborators

Completed

Thymus Transplantation in DiGeorge Syndrome #668

DiGeorge Syndrome | Complete Typical DiGeorge Anomaly

United States
Masonic Cancer Center, University of Minnesota

Completed

TBI Dose De-escalation for Fanconi Anemia

Fanconi Anemia

United States
University of Tennessee Medical Center

Completed

Clonidine Versus Phenobarbital as Adjunctive Therapy for Neonatal Abstinence Syndrome

Neonatal Abstinence Syndrome

United States
Massachusetts General Hospital

Completed

Renal Allograft Tolerance Through Mixed Chimerism (Belatacept)

Renal Insufficiency | Kidney Failure, Chronic

United States
Massachusetts General Hospital

Completed

Renal Allograft Tolerance Through Mixed Chimerism

End Stage Renal Disease

United States
National Cancer Institute (NCI)

Completed

Pilot Study of Leuprolide to Improve Immune Function After Allogeneic Bone Marrow Transplantation

Chronic Myelomonocytic Leukemia | Myelodysplastic Syndrome | Acute Lymphocytic Leukemia | Acute Myelogenous Leukemia | Chronic Myelogenous Leukemia

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Terminated

Methadone, Morphine, or Oxycodone in Treating Pain in Patients With Cancer

Pain | Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Brain and Central Nervous System Tumors | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm | Precancerous Condition | Lymphoproliferative Disorder | Myelodysplastic/Myeloproliferative...

United States
Chiesi Farmaceutici S.p.A.

Completed

First In Human Study on Synthetic Surfactant CHF 5633 in Respiratory Distress Syndrome

Respiratory Distress Syndrome in Premature Infants

United Kingdom
Kanuni Sultan Suleyman Training and Research Hospital

Unknown

Is Thymus Size of Infants Who Born to COVID-19 Positive Mothers Associated With Neonatal Morbidities?

Covid19 | Thymic Hypoplasia

Turkey
Massachusetts General Hospital

Completed

Combined Bone Marrow Transplantation (BMT) and Renal Transplant for Multiple Myeloma (MM) With End Stage Renal Disease (ESRD)

Multiple Myeloma | End Stage Renal Disease

United States
Mayo Clinic
National Cancer Institute (NCI)

Completed

Salvia Hispanica Seed in Reducing Risk of Disease Recurrence in Patients With Non-Hodgkin Lymphoma

Diffuse Large B-Cell Lymphoma | Splenic Marginal Zone Lymphoma | Mantle Cell Lymphoma | Mycosis Fungoides | Sezary Syndrome | Lymphoplasmacytic Lymphoma | Anaplastic Large Cell Lymphoma | Blastic Plasmacytoid Dendritic Cell Neoplasm | Primary Effusion Lymphoma | Adult T-Cell Leukemia/Lymphoma | Post-Transplant... and other conditions

United States
Vinmec Research Institute of Stem Cell and Gene...

Completed

Improvement in Gross Motor Function and Muscle Tone in Children With Cerebral Palsy Related to Neonatal Icterus

Cerebral Palsy

Vietnam
University of Pennsylvania

Completed

Fetal Thymus Involution as a Predictor of Adverse Neonatal Outcomes (TIPS)

Women Admitted to Labor and Delivery for the Management of Preterm Labor and/or Preterm Premature Rupture of Membranes (PPROM)

United States
M.D. Anderson Cancer Center
Enzon Pharmaceuticals, Inc.

Completed

Oral Posaconazole Three Times Per Day vs Weekly High Dose Amphotericin B Lipid Complex (ABLC)

Invasive Fungal Infections | Hematologic Malignancies

United States
National Heart, Lung, and Blood Institute (NHLBI)
University of Pittsburgh

Terminated

Thymic Tolerance in Pediatric Heart Transplantation

Heart Transplantation

United States
Daniel Bernstein

Completed

B-Receptor Signaling in Cardiomyopathy

Soft Tissue Sarcoma | Lymphoma, Non-Hodgkin | Leukemia | Breast Cancer | Myeloproliferative Disorders | Multiple Myeloma | Anemia | Pancreatic Cancer | Hodgkin Disease | Esophageal Cancer | Amyloidosis | Lung Cancer | Bone Cancer | Prostate Cancer | Neuroendocrine Tumors | Mesothelioma | Skin Cancer | Thyroid Cancer | Anal Cancer | Hepatobiliary Neoplasm and other conditions

United States
National Institute of Allergy and Infectious Diseases...
Immune Tolerance Network (ITN)

Completed

Combined Kidney and Bone Marrow Transplantation to Prevent Kidney Transplant Rejection

Kidney Failure, Chronic | Kidney Transplantation

United States
Universitaire Ziekenhuizen KU Leuven
Institutul Clinic Fundeni

Completed

A New Dosing Regimen for Posaconazole Prophylaxis in Children Based on Body Surface Area

Hematological Malignancy

Belgium, Romania
University of Chicago

Terminated

Minor Histocompatibility Vaccination After Allogeneic Stem Cell Transplantation for Advanced Hematologic Malignancies

Lymphoma | Preleukemia | Myeloproliferative Disorders | Myeloma | Graft Versus Host Disease

United States
INSYS Therapeutics Inc
National Cancer Institute (NCI)

Completed

Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer Pain

Cancer

United States
Al-Azhar University
Cairo University; Affiliated Hospital to Academy of Military Medical Sciences

Unknown

Transurethral Myoblast Injection for Urinary Incontinence in Children With Bladder Exstrophy

Urinary Incontinence

Egypt
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Completed

Umbilical Cord Blood Transplantation in Treating Patients With Hematologic Cancer or Other Hematologic or Metabolic Diseases

Myelodysplastic Syndromes | Leukemia | Thymic Carcinoma | Graft Versus Host Disease

United States

Search clinical trials for: Neonatal thymus transplant

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