Search clinical trials for: Next generation sequencing exome

Total 4333 results

University Hospital Tuebingen

Recruiting

Diagnostic Value of Exome/ Genome Sequencing, Conventional Methods in Rare Diseases and Familial Tumor Syndromes (EXGEFATU)

Rare Diseases | Genetic Predisposition

Germany
Institut National de la Santé Et de la Recherche...
Institut Bergonié; Commissariat A L'energie Atomique; Plateforme labellisée Inca... and other collaborators

Active, not recruiting

Molecular Profiling of Advanced Soft-tissue Sarcomas (MULTISARC)

Soft Tissue Sarcoma

France
University of North Carolina, Chapel Hill
National Human Genome Research Institute (NHGRI); East Carolina University; Mission...

Active, not recruiting

North Carolina Genomic Evaluation by Next-generation Exome Sequencing, 2 (NCGENES2)

Neuromuscular Diseases | Movement Disorders | Intellectual Disability | Autism Spectrum Disorder | Microcephaly | Hearing Loss | Genetic Disease | Inborn Errors of Metabolism | Epilepsy; Seizure | Brain Malformation | Hypotonia | Development Delay | Chromosome Abnormality | Dysmorphic Features | Skeletal Dysplasia | Congenital... and other conditions

United States
Leiden University Medical Center

Enrolling by invitation

Evaluating Prenatal Exome Sequencing Study (EPES)

Genetic Diseases, Inborn | Mendelian Disorders | Congenital Anomalies

Netherlands
University of California, San Francisco
National Human Genome Research Institute (NHGRI)

Completed

Clinical Utility of Pediatric Whole Exome Sequencing

Epilepsy | Cerebral Palsy | Intellectual Disability | Developmental Delay | Metabolic Disease | Neuro-Degenerative Disease | Encephalopathy | Birth Defect | Multiple Congenital Anomaly | Developmental Defect

United States
Rennes University Hospital

Completed

Retrospective Study Using Next Generation Sequencing (NGS) on Biological Samples to Improve Genetic Counseling for Patients With Previously Explored Craniofacial Midline Defects. (EXOMEDIANE)

Holoprosencephaly

France
Imperial College London Diabetes Centre

Unknown

Application of UCPCR as a Testing Tool for Identification of MODY Patients in the UAE

Diabetes Mellitus, Type 2 | Diabetes Mellitus, Type 1 | Maturity-onset Diabetes of the Young

United Arab Emirates
University Hospital, Montpellier

Completed

Identification of Genes Involved in Juvenile Idiopathic Arthritis by Wholel Exome Sequencing (GenesinJIA)

Arthritis, Juvenile Rheumatoid
University Hospital, Strasbourg, France

Completed

Severe PID With Lymphoproliferation and Neutropenia (DICEP)

Primary Immune-Deficiency (PID) Common Variable Immune Deficiency (CVID)

France
Rennes University Hospital

Completed

Improving Genetic Counseling for Patients With Spina Bifida Using Next Generation Sequencing (EXOSPINA)

Spina Bifida

France
Institut National de la Santé Et de la Recherche...
Institut Bergonié; Plateforme labellisée Inca - Institut Bergonié, Bordeaux; Plateforme... and other collaborators

Completed

Molecular Profiling to Improve Outcome of Patients in Cancer. A Pilot Study (MULTIPLI-0)

Soft Tissue Sarcoma | Colorectal Carcinoma

France
National Taiwan University Hospital
Ministry of Science and Technology, Taiwan

Unknown

Rapid Genetic Diagnosis Employing Next Generation Sequencing for Critical Illness in Infants and Children

Acute Disease | Congenital Metabolic Disorder

Taiwan
University Hospital, Strasbourg, France

Unknown

Identification of Mutations Responsible for Rare Familial Skin Diseases by Next Generation Sequencing (DERMA-SEQ)

Familial Lipomatosis | Very Rare Dermatologic Diseases

France
Hospices Civils de Lyon

Unknown

Clinical and Genetic Study of Familial Sarcoidosis (SARCFAM) (SARCFAM)

Sarcoidosis

France
Gattaca Genomics

Recruiting

Embryo Assessment Utilizing Timelapse Imaging in Conjunction With Preimplantation Genetic Testing for Aneuploidy With Next Generation Sequencing

Infertility | Aneuploidy | Infertility, Female | Infertility, Male | IVF

United States
OncoAtlas LLC
N.N. Blokhin National Medical Research Center of Oncology; Moscow MultidisciplinaryClinical...

Recruiting

Dynamics of MSI and Genomic Profile of Colorectal Cancer In the Course of Immune Checkpoint Inhibitor Therapy (BLOOMSI)

Cancer | Colorectal Cancer | Colorectal Cancer Metastatic | Colon Adenocarcinoma | MSI-H Colorectal Cancer | dMMR Colorectal Cancer

Russian Federation
University of Missouri-Columbia

Recruiting

Baker Gordon Syndrome Natural History Study (BAGOS)

Epilepsy, Generalized | Sleep Disorder | Rare Diseases | Development Delay | Motor Delay | Autism or Autistic Traits | SYT-SSX Fusion Protein Expression

United States
Instituto de Investigación Biomédica de Salamanca
Carlos III Health Institute

Recruiting

Unified platforM for a Better integRal Evaluation of MyeLodyspLastic Syndromes in SpAin-Strategy for Unraveling Personalized genoMic Medicine in Public heAlth System (UMBRELLA-SUMMA) (UMBRELLA-SUMMA)

Myelodysplastic Syndromes

Spain
University of Aarhus
Aarhus University Hospital

Recruiting

Circulating Tumor DNA in Peripheral T-cell Lymphomas (CIRCULATE)

Peripheral T-cell Lymphoma | NK/T-Cell Lymphoma

Denmark
Siriraj Hospital

Not yet recruiting

Disease Characteristics and Treatment Response in Plasma Cell Disorders Patients Based on Genetic Abnormalities From Fluorescence In Situ Hybridization and Next Generation Sequencing (genetics MM)

Plasma Cell Disorder
King Chulalongkorn Memorial Hospital

Recruiting

Duodenal Microbiota in Functional Dyspepsia

Functional Dyspepsia

Thailand
Hunan Cancer Hospital

Recruiting

Sequencing-based Counting of Plasma Epstein-Barr Virus DNA in Non-metastatic Nasopharyngeal Carcinoma

Nasopharyngeal Carcinoma | Herpesvirus 4, Human

China
Yunfeng Hou

Not yet recruiting

The Value of mNGS in Diagnosis of Pulmonary Infection

Pulmonary Infection
Pusan National University Hospital

Not yet recruiting

Feasibility of Targeted Bronchial Washing for Molecular Testing by Next Generation Sequencing in Early-stage Lung Cancer

Lung Cancer
Interni hematologicka klinika FNKV
Charles University, Czech Republic; University Hospital Olomouc; General University... and other collaborators

Recruiting

Prognostic Significance of ctDNA in HL

Prognostic Cancer Model

Czechia
Tempus AI

Recruiting

TEMPUS ARIES: A Biobank Registry Platform Study in Oncology

Cancer

United States
Duke University
National Institute of Allergy and Infectious Diseases (NIAID)

Recruiting

Pneumonia Direct Pilot (PDP)

Pneumonia, Bacterial | Ventilator Associated Pneumonia

United States
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Diagnostic Efficacy of Metagenomic Next-generation Sequencing in Patients With Spinal Infections: A Retrospective Study

Spinal Infection | Diagnositic Efficacy

China
ART Fertility Clinics LLC

Recruiting

Hyaluronan-enriched Medium and Euploid Blastocyst Transfers (GluePloid)

Infertility | Live Birth Rate | Clinical Pregnancy Rate | Implantation Rate | FET | Blastocysts

United Arab Emirates
National Taiwan University Hospital
National Health Research Institutes, Taiwan; National Science and Technology...

Recruiting

Precision Medicine for Nociception, Sngception and Proprioception.

Rehabilitation | Pain, Chronic | Idiopathic Scoliosis | Pain, Shoulder

Taiwan
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Not yet recruiting

Detection of Pathogen and Antibiotic Resistance Genes by Targeted Next-Generation Sequencing in ICU Patients.

Infections | Critical Illness | Diagnosis
Pusan National University Hospital

Not yet recruiting

Feasibility of Bronchial Washing Fluid for Molecular Testing With Next Generation Sequencing in Lung Cancer

Lung Cancer

Korea, Republic of
Fujian Cancer Hospital
First Affiliated Hospital of Fujian Medical University; Fujian Provincial Hospital and other collaborators

Not yet recruiting

MRI Radiomics Combined With Pathomics on the Prediction of Molecular Classification and Prognosis of Endometrial Cancer

Endometrial Neoplasms

China
Vanderbilt-Ingram Cancer Center

Not yet recruiting

TBNA vs EBUS-TBNA Plus Transbronchial Mediastinal Cryobiopsy for Adequacy of Next Generation Sequencing (META-Gen)

Lung Cancer

United States
Centre Henri Becquerel

Not yet recruiting

Circulating Tumor DNA Sequencing in Patients With Peripheral T-cell Lymphomas (PTCL-SEQ)

Peripheral T Cell Lymphoma

France
Chinese University of Hong Kong

Not yet recruiting

Prospective Clinical Validation of Next Generation Sequencing (NGS) and Patient-Derived Tumor Organoids (PDO) Guided Therapy in Patients With Advanced/ Inoperable Solid Tumors (PDO)

Hepatocellular Carcinoma | Colorectal Cancer

Hong Kong
University Hospital Tuebingen
Charite University, Berlin, Germany; RWTH Aachen University; Medical University...

Not yet recruiting

Initiative for Clinical Long-read Sequencing (IonGER)

Genetic Predisposition

Germany
Nanfang Hospital, Southern Medical University

Recruiting

Pathogenic Metagenomic Next-generation Sequencing to Optimize the Diagnosis of Decompensated Cirrhosis Infection

Cirrhosis, Liver

China
Tianjin Medical University Second Hospital

Recruiting

MyCustom:Prospective Master Protocol Trial on Precision Medicine Treatment for Refractory Solid Tumors

Refractory Solid Tumors | Next Generation Sequencing

China
Centro di Riferimento Oncologico - Aviano

Recruiting

A Study on the Prevalence of Clinically Useful Mutations in Solid Tumor Characterized by Next Generation Sequencing Methods on Liquid Biopsy Analysis (POPCORN) (POPCORN)

Melanoma | Cervical Cancer | Breast Cancer | Gastric Cancer | Pancreatic Cancer | Ovarian Cancer | Solid Tumor | Bile Duct Cancer | Advanced Solid Tumor | Endometrial Cancer | Hepatocarcinoma | Locally Advanced Solid Tumor | Colon Rectal Cancer | Vulva Cancer

Italy
National Taiwan University Hospital
Far Eastern Memorial Hospital; National Taiwan University Hospital Hsin-Chu...

Not yet recruiting

Metagenomic NGS for Diagnosis of Pneumonia

Pneumonia | Diagnosis
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...

Recruiting

Prospective Evaluation of Diagnosis and Treatment of Patients With Autoimmune Cytopenias Including Autoimmune Hemolytic Anemia, Immune Thrombocytopenia, and Chronic Idiopathic/Autoimmune Neutropenia (AIHA ITP CIN)

Myelodysplastic Syndromes | Immune Thrombocytopenia | Autoimmune Hemolytic Anemia | Cold Agglutinin Disease | Autoimmune Neutropenia | Chronic Idiopathic Neutropenia

Italy
Jian-Xin Zhou

Recruiting

Economic Impact of mNGS on Diagnosis of Post-neurosurgical Central Nervous System Infection (mNGS)

Central Nervous System Infections

China
University Hospital Tuebingen
German Consortium for Translational Cancer Research

Not yet recruiting

CIRculating Cell-free nUcLeic Acids in Cancer Therapy Monitoring -01 (CIRCULATING-01)

Next-Generation-Sequencing
Charu Aggarwal
Loxo Oncology, Inc.

Recruiting

Liquid Biopsy Based NGS in Newly Diagnosed NSCLC (iNUDGE)

Non Small Cell Lung Cancer Metastatic | Non-Squamous Non-Small Cell Neoplasm of Lung | Newly Diagnosed NSCLC

United States
Xiaojun Xu

Not yet recruiting

Minimal Residual Disease Quantification by Next-generation Sequencing in Pediatric B-ALL Children Patients Treated With Blinatumomab Consolidation

Acute Lymphoblastic Leukemia, Pediatric
Jagiellonian University

Recruiting

Endometriosis and Peritoneal Dysbiosis

Endometriosis | Infertility Unexplained

Poland
University of Miami

Recruiting

Levels of Circulating Tumor DNA as a Predictive Marker for Early Switch in Treatment for Patients With Metastatic (Stage IV) Breast Cancer

Breast Cancer | Metastatic Breast Cancer | ER-positive Breast Cancer | HER2-negative Breast Cancer

United States
Boris Böll
Noscendo GmbH

Not yet recruiting

Next-Generation-Sequencing Approach to Neutropenic Sepsis (NEXUS)

Febrile Neutropenia
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Study to Assess the Feasibility in Bile cfDNA of Resectable Biliary Tract Carcinomas

This Study Aims to Reveal the Effectiveness, Accuracy, and Feasibility in Bile

China

Search clinical trials for: Next generation sequencing exome

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