Search clinical trials for: Non covalent

Total 53114 results

Biomea Fusion Inc.

Recruiting

Study of Covalent Menin Inhibitor BMF-219 in Adult Patients With KRAS Driven Non-Small Cell Lung Cancer, Pancreatic Cancer, and Colorectal Cancer

Colorectal Cancer | Pancreatic Cancer | NSCLC | Non Small Cell Lung Cancer | Stage III Pancreatic Cancer | Stage IV Pancreatic Cancer | CRC | KRAS Mutation-Related Tumors | Relapsed Cancer | Refractory Cancer | Stage IV Non-small Cell Lung Cancer | Stage IV Colorectal Cancer | Stage III Non-small Cell Lung Cancer | Stage III NSCLC and other conditions

United States, Korea, Republic of
Biomea Fusion Inc.

Recruiting

Study of BMF-219, a Covalent Menin Inhibitor, in Adult Patients With AML, ALL (With KMT2A/ MLL1r, NPM1 Mutations), DLBCL, MM, and CLL/SLL

Lymphoma | Lymphoma, Non-Hodgkin | Acute Myeloid Leukemia | Cancer | Progression | Multiple Myeloma | Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | Plasma Cell Myeloma | Diffuse Large B Cell Lymphoma | Small Lymphocytic Lymphoma | Refractory | Myeloma, Plasma-Cell | Myelomatosis | Acute Mixed-Phenotype...

United States, Spain, Netherlands, Greece, Italy
Aptose Biosciences Inc.

Active, not recruiting

A Study of CG-806 in Patients With Relapsed or Refractory AML or Higher-Risk MDS

Acute Myeloid Leukemia | Myelodysplastic Syndromes

United States
Ahram Canadian University

Not yet recruiting

Relation Between Muscle Mass, Total Body Fat, Visceral Fat, Waist Hip Ratio and Sleeping Hours in Patient With Nonspecific Back Pain

Obesity | Back Pain | Sleep
Pak Emirates Military Hospital

Not yet recruiting

Comparison of Efficacy of Methotrexate and Azathioprine in Patients With Chronic Actinic Dermatitis: A Randomized Controlled Trial

Chronic Actinic Dermatitis
Vertanical GmbH

Not yet recruiting

Dose-Response Characterization of VER-01 in the Treatment of Patients With Chronic Non-specific Low Back Pain (RESPONSE)

Chronic Non-specific Low Back Pain
Tang-Du Hospital

Not yet recruiting

Neoadjuvant/Adjuvant Tislelizumab Combined With Anlotinib and Platinum Doublet Chemotherapy With Resectable NSCLC

Non-Small Cell Lung Cancer | Anti Angiogenesis

China
Sichuan Baili Pharmaceutical Co., Ltd.
Baili-Bio (Chengdu) Pharmaceutical Co., Ltd.

Not yet recruiting

A Study of BL-B01D1+PD-1 Monoclonal Antibody in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer, Nasopharyngeal Carcinoma and Other Solid Tumors

Nasopharyngeal Carcinoma | Solid Tumor | Non-small Cell Lung Cancer

China
Fundacion Universitaria Maria Cano

Recruiting

Effectiveness of Physical Exercise of Patients With Chronic Non-communicable Disease

Diabetes | Frailty | COPD | Physical Inactivity

Colombia
Xadcera Biopharmaceutical (Suzhou) Co., Ltd.

Not yet recruiting

A Study of DM001 in Patients With Advanced Solid Tumors

Breast Neoplasms | Carcinoma, Non-Small-Cell Lung | Solid Carcinoma
Eli Lilly and Company

Not yet recruiting

A Bioequivalence Study of Citrate Free Mirikizumab (LY3074828) in Healthy Participants

Healthy

United States
Bristol-Myers Squibb

Not yet recruiting

A Study to Evaluate the Safety, Tolerability, and Efficacy of Escalating Doses of BMS-986463 in Participants With Select Advanced Malignant Tumors.

Non-small Cell Lung Cancer (NSCLC) | High-grade Serous Ovarian Carcinoma (HGSOC) | Uterine Serous Carcinoma (USC)

United States, Canada
Atif Shafqat

Recruiting

Opioid-based Versus Opioid-free Anaesthesia for Laparoscopic Cholecystectomy

Laparoscopic Cholecystectomy | Surgical Procedure, Unspecified

Pakistan
Dana-Farber Cancer Institute
Merck Sharp & Dohme LLC

Not yet recruiting

Pembrolizumab + Chemotherapy in Newly Diagnosed PCNSL

Lymphoma | Primary Central Nervous System Lymphoma

United States
Guy's and St Thomas' NHS Foundation Trust
University of Nottingham; Liverpool Heart and Chest Hospital NHS Foundation... and other collaborators

Not yet recruiting

Using AI Within Digital Wound Monitoring of Surgical Wounds to Prioritise Non-healing Wounds for Urgent Review (WISDOM)

Surgical Wound | Heart; Surgery, Heart, Functional Disturbance as Result | Wound Healing Delayed

United Kingdom
Sahmyook University

Not yet recruiting

Effects of a Cognitive Gait Dual Task With Smartglasses in Stroke Patients (stroke)

Stroke

Korea, Republic of
The First People's Hospital of Lianyungang

Recruiting

SRT Combined With Anlotinib for the Treatment of Brain Metastases From Non-small Cell Lung Cancer

Brain Metastases | Non-Small-Cell Lung Cancer

China
Yale University

Not yet recruiting

Submaximal Cardiopulmonary Exercise Testing for Detection of Myocardial Injury After Noncardiac Surgery (EnhanceMINS)

Preoperative Period | Submaximal Exercise Performance | Myocardial Injury After Non-cardiac Surgery

United States
Altria Client Services LLC
ICON Clinical Research

Not yet recruiting

Room Air Levels of Harmful and Potentially Harmful Constituents After Heated Tobacco Product Use and Combustible Cigarettes

Tobacco Use | Tobacco Smoking

United States
Assistance Publique - Hôpitaux de Paris
Institut National de la Santé Et de la Recherche Médicale, France

Not yet recruiting

Design, Implementation and Evaluation of an Intervention Within Video Game for Mental Health Literacy in Adolescents and Young Adults (SCOTT)

Mental Health Literacy

France
Assaf-Harofeh Medical Center

Recruiting

Comparison of the Effect of K Ketalar or Dexmedetomidine on Increased Sensitivity to Pain Induced Following Treatment With Remifentanil

Cholecystectomy

Israel
Vejle Hospital
University of Aarhus; University of Southern Denmark; Region of Southern Denmark and other collaborators

Not yet recruiting

Reducing Breathlessness With Dronabinol in COPD Patients (BONG)

Cannabis | COPD | Breathlessness
Neuropix

Not yet recruiting

Non-invasive Auricular Fiber Vagus Nerve Stimulation (afVNS) for Treatment of Autism Spectrum Disorder

Autism Spectrum Disorder
Distalmotion SA
confinis AG

Not yet recruiting

The DEXTER-assisted Non-acutE cholecyStecTomy Study (The NEST Study)

Cholecystectomy
Shanghai Juncell Therapeutics

Not yet recruiting

A Phase Ⅰb Study on Autologous GC101 TIL Injection for the Treatment of NSCLC (MIZAR-005)

Non Small Cell Lung Cancer | Non Small Cell Lung Cancer Metastatic
OSE Immunotherapeutics
Exystat; Genome Diagnostics (GenDx)

Not yet recruiting

Trial of Therapeutic Cancer Vaccine OSE2101 in Patients With Non-Small Cell Lung Cancer and Secondary Resistance to Immune Checkpoint Inhibitor (ARTEMIA)

Patients With Non-Small Cell Lung Cancer

United States
University of Erlangen-Nürnberg Medical School

Recruiting

Non-invasive Evaluation of Graft Condition in Adult Patients With Kidney Transplant Using Ultrasound Localization Microscopy and Multispectral Optoacoustic Tomography (ESTIMATOR)

Kidney Transplant | Kidney Biopsy

Germany
Mohammed Abdulhameed

Not yet recruiting

This Study Assess Some Physiological Parameters, Blood Picture, and Hemodynamic Parameters, Blood Pressure, Respiratory Assess by SPO2, During Different Periods in Laparoscopic Surgery (laparoscopy)

Anesthesia Complication | Physiological Parameter
AstraZeneca

Recruiting

Clinical and demOgRaphic Features of Patients With Uncontrolled Severe Asthma in Russia (CORSAR) (CORSAR)

Severe Asthma

Russian Federation
Tianjin Medical University Cancer Institute and...

Not yet recruiting

Zanubrutinib and G-CHOP in Untreated Intermediate-high Risk Follicular Lymphoma

FL
University of Basel

Recruiting

Sustainable Improvement of INTERprofessional Care for Better Resident Outcomes (INTERSCALE)

Unplanned Hospitalizations

Switzerland
Mayo Clinic

Recruiting

Insomnia in Patients With Metastatic Lung Cancer

Metastatic Lung Non-Small Cell Carcinoma | Stage IV Lung Cancer AJCC v8

United States
General Hospital of Ningxia Medical University

Not yet recruiting

Non-invasive vs Invasive Cardiac Output Monitoring During Cesarean Section

Hemodynamics
BrainCare Medical Group

Not yet recruiting

The Impact of Eye and Body Training on the Injury Rate of Concussions in Female Soccer Players

Musculoskeletal Pain | Concussion, Brain
Chinese PLA General Hospital

Recruiting

A Phase ll Trial of the Combination of Zanubrutinib, Rituximab and Venetoclax in Patients With Previously Untreated Follicular Lymphoma (ZARAV)

Ann Arbor Stage II Follicular Lymphoma | Ann Arbor Stage III Follicular Lymphoma | Ann Arbor Stage IV Follicular Lymphoma | Grade 1 Follicular Lymphoma | Grade 2 Follicular Lymphoma | Grade 3a Follicular Lymphoma

China
Mayo Clinic

Not yet recruiting

Feasibility of Patient-Centered Home Care (PCHC) to Reduce Disparities in High-Risk Black Men (BM) With Advanced Prostate Cancer (CaP)

Stage III Prostate Cancer AJCC v8 | Stage IVB Prostate Cancer AJCC v8 | Metastatic Prostate Adenocarcinoma | Advanced Prostate Adenocarcinoma

United States
GlaxoSmithKline
iTeos Therapeutics

Recruiting

A Study of Belrestotug Plus Dostarlimab Compared With Placebo Plus Pembrolizumab in Previously Untreated Participants With Programmed Death Ligand 1 (PD-L1) High Non-small-cell Lung Cancer (NSCLC)

Lung Cancer, Non-Small Cell

Argentina, Belgium, Brazil, Canada, Finland, Germany, Italy, Japan, Mexico, Panama, Spain, Taiwan, Turkey, Poland, Netherlands, Korea, Republic of, France, Greece, Bulgaria, Croatia, Czechia, Estonia, Hong Kong, Hungary, India, Philippines, Portuga... and more
Xuanwu Hospital, Beijing

Not yet recruiting

Clinical Multicenter Randomized Controlled Study of Non-invasive Brain Oscillation Modulation in the Treatment of AD-MCI Patients

AD-MCI

China
University of Chicago

Not yet recruiting

Effects of Drugs on Stress Memories (ETS)

Stress | THC

United States
Soligenix

Not yet recruiting

Confirmatory Study of Topical HyBryte™ vs. Placebo for the Treatment of CTCL (FLASH2)

Mycosis Fungoides | Cutaneous T Cell Lymphoma | CTCL | CTCL/ Mycosis Fungoides
Zaparackas and Knepper LTD
Northwestern University Feinberg School of Medicine

Not yet recruiting

RQC for the Prevention of Alzheimer's Disease and Retinal Amyloid-β

Alzheimer Disease | Mild Cognitive Impairment | Cognitive Decline

United States
Institut Cancerologie de l'Ouest

Not yet recruiting

Corticodependent or Corticoresistant Brain Radionecrosis After Radiotherapy for Brain Metastases (BRADI)

Brain Metastases | Radionecrosis of Brain

France
Janssen Research & Development, LLC

Recruiting

A Study of JNJ-88998377 for Relapsed/Refractory B-cell Non-Hodgkin's Lymphoma

Lymphoma, Non-Hodgkin | Relapsed B-cell NHL | Refractory B-Cell NHL

Turkey
University of South Carolina
National Institute on Drug Abuse (NIDA)

Recruiting

Theory-based Social Media Intervention for Non-medical Use of Prescription Opioids in Young Adults

Young Adults | Past-3-month Non-medical Use of Prescription Opioids | Without Substance Use Disorders | Social Media Users

United States
Lakehead University

Not yet recruiting

The Short-Term Effects of Dry Cupping the Lumbar Paraspinal Muscles in Individuals With Non-specific Low Back Pain

Non-specific Low Back Pain
Poznan University of Medical Sciences

Not yet recruiting

Dexamethasone vs. Dexmedetomidine for ESPB in Pain Management After Knee Arthroplasty

Knee Osteoarthritis | Knee Arthritis | Knee Pain Chronic | Knee Disease

Poland
Mayo Clinic

Not yet recruiting

Mapping of Electrical Properties in the Brain

Malignant Glioma

United States
Beijing Chest Hospital, Capital Medical University

Not yet recruiting

Adebrelimab Plus Chemo and Recaticimab Perioperative Treatment for Resectable NSCLC

Non Small Cell Lung Cancer

China
Ohio State University
Patient-Centered Outcomes Research Institute; Northwestern University; Preeclampsia...

Not yet recruiting

Effectiveness of Two Aspirin Doses for Prevention of Hypertensive Disorders of Pregnancy: ASPIRIN TRIAL (ASPIRIN)

Preeclampsia | Gestational Hypertension | Hypertensive Disorders of Pregnancy

United States
Hospices Civils de Lyon

Not yet recruiting

Decoding Motor Imagery From Non-invasive Brain Recordings as a Prerequisite for Innovative Motor Rehabilitation Therapies (MODECO)

Motor Imagery | Upper Limb Deficit After Stroke

France

Search clinical trials for: Non covalent

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