Search clinical trials for: Non-transfusion dependent

Total 3781 results

Regeneron Pharmaceuticals

Not yet recruiting

A Study to Test the Safety, Tolerability, and Efficacy of an Antibody, REGN7999, Injected Under the Skin for the Treatment of Iron Overload in Adult Participants With Non-Transfusion Dependent β-thalassemia, Using MRI Scans to Measure Iron Levels in the Body (FERVENT-1)

Non-transfusion Dependent Beta-thalassemia (NTDT)
Bristol-Myers Squibb

Recruiting

A Study to Determine the Efficacy and Safety of Luspatercept in Adult and Adolescent Participants With Alpha (α)-Thalassemia

Anemia

Thailand, China, Canada, Turkey, Greece, Taiwan, Italy, Hong Kong
Phoenicia BioScience
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

The BENeFiTS Trial in Beta Thalassemia Intermedia (PB04-001)

Sickle Cell Disease | Beta Thalassemia Intermedia

United States, Canada
Silence Therapeutics plc

Completed

A Study Investigate the Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Response of SLN124 in Adults With Alpha/Beta-thalassaemia and Very Low- and Low-risk Myelodysplastic Syndrome

Non-transfusion-dependent Thalassemia | Low Risk Myelodysplastic Syndrome | Very-Low Risk Myelodysplastic Syndrome

Thailand, Israel, Jordan, United Kingdom, Germany, Italy, Malaysia
Vifor (International) Inc.
Labcorp Corporation of America Holdings, Inc

Completed

Safety, Tolerability, Pharmacokinetics (PK), Pharmacodynamics (PD) and Preliminary Efficacy of VIT-2763 in β-thalassaemia (VITHAL)

Beta-Thalassemia | Non-transfusion-dependent Thalassemia

Greece, Israel, Italy, Lebanon, Thailand
Novartis Pharmaceuticals

Completed

Open-label, Multicenter Study Assessing Preference for Deferasirox Film-coated Tablet Compared to Dispersible Tablet (Jupiter)

Non-transfusion-dependent Thalassemia | Transfusion-dependent Thalassemia

Egypt, Turkey, Thailand, Lebanon, Morocco, Saudi Arabia, Vietnam
Silence Therapeutics plc

Withdrawn

Study in Beta-thalassaemia or Myelodysplastic Syndrome Patients to Investigate the Safety and Tolerability of SLN124

Non-transfusion-dependent Thalassemia | Low Risk Myelodysplastic Syndrome

United Kingdom, Bulgaria
Novartis Pharmaceuticals

Completed

Efficacy and Safety Study of Deferasirox in Patients With Non-transfusion Dependent Thalassemia (THETIS)

Non-transfusion Dependent Thalassemia

Thailand, Turkey, Italy, Greece, China, United Kingdom, Lebanon, Tunisia
Celgene

Completed

To Document the Burden of Illness on the Quality of Life and the Impact on Healthcare Utilization in (Beta) β-thalassemia Subjects Who Are Transfusion Dependent (TD) and Non-transfusion Dependent (NTD) Receiving Standard of Care

Beta-Thalassemia

Greece, Italy, Lebanon, Thailand, Turkey
Novartis Pharmaceuticals

Completed

Efficacy and Safety of Deferasirox in Non-transfusion Dependent Thalassemia Patients With Iron Overload and a One Year Open-label Extension Study (THALASSA)

Non-transfusion Dependent Thalassemia

Greece, Taiwan, Italy, United Kingdom, Lebanon, Turkey, Malaysia, Thailand, United States
Afyonkarahisar Health Sciences University

Recruiting

Postoperative Pain Control Following Hysteroscopy

Postoperative Pain | Analgesia | Postoperative Nausea

Turkey
E-DA Hospital

Recruiting

2% Lidocaine Gel in Reducing Postoperative Pain Following Haemorrhoidectomy

Pain, Postoperative | Surgery

Taiwan
University Hospital, Gentofte, Copenhagen

Recruiting

The Glucagonotropic Effects of Glucose-dependent Insulinotropic Polypeptide and Alanine in Healthy Individuals (GIPALANIN)

Effect of iv Administration of GIP and Alanine

Denmark
Eli Lilly and Company

Not yet recruiting

A Study Comparing Abemaciclib Plus Temozolomide to Temozolomide Monotherapy in Children and Young Adults With High-grade Glioma Following Radiotherapy

Glioma

United States
Ulrich Ronellenfitsch, MD
German Federal Ministry of Education and Research; Coordinating Centre for...

Not yet recruiting

Tranexamic Acid for Reduction of Transfusion in Abdominal Surgery (TATRA)

Surgical Blood Loss | Transfusion-dependent Anemia | Abdomen Disease

Germany
M.D. Anderson Cancer Center

Not yet recruiting

Phase II Study of REPotrectinib With or Without Fulvestrant in Patients With Hormone Receptor-positive Human Epidermal Growth Factor 2-negative Metastatic Invasive LObular Carcinoma Who Received a Prior Endocrine Therapy in Combination With Cyclin-dependent Kinase 4 and 6 Inhibitor (REPLOT Trial)

Hormone Receptor-positive Human Epidermal Growth Factor 2-negative | Metastatic Invasive LObular Carcinoma

United States
University of Calgary

Not yet recruiting

Ablation Index in Standard vs. High Power Radiofrequency Ablation for Typical Atrial Flutter: A Randomized Study (AITAF) (AITAF)

Atrial Flutter | Atrial Flutter Typical | Cavotricuspid Isthmus Dependent Macroreentry Tachycardia

Canada
West China Hospital

Recruiting

Effect of Lidocaine on Postoperative Pain and Long-term Survival in Elderly Patients Undergoing Colorectal Surgery

Colorectal Cancer

China
University of Ioannina

Recruiting

Opioid-free Anaesthesia in Breast Cancer Surgery

Pain, Postoperative | Breast Cancer | Anesthesia | Pain, Chronic | Cancer Recurrence | Opioid Free Anaesthesia

Greece
National University of Singapore
National University Polyclinics, Singapore

Not yet recruiting

Intensive Aerobic and Resistance Exercise Program (IAREP)

Type 2 Diabetes Mellitus | Cognitive Impairment | Cognitive Dysfunction | Non-insulin-dependent Diabetes Mellitus
Ain Shams University

Recruiting

Effect of Topical Airway Block on Hemodynamic Stability Post Induction of Anaesthesia in Cardiac Surgeries (hemodynamics)

Cardiac Surgery

Egypt
Sinclair Pharmaceuticals Limited

Recruiting

A Study to Evaluate the Safety and Effectiveness of Injectable Gel for Correction of Infraorbital Hollowing in Chinese Population

Infraorbital Hollowing

China
Washington University School of Medicine

Not yet recruiting

LIMIT Trial - Lidocaine With Intramuscular Injection of Benzathine Penicillin G for Treponema Pallidum Treatment (LIMIT)

Syphilis Infection | Benzathine Penicillin Adverse Reaction
Nordsjaellands Hospital

Recruiting

Combining Lidocaine and Ropivacaine for an Infraclavicular Brachial Plexus Nerve Block

Anesthesia, Local | Surgery | Brachial Plexus Block | Nerve Block | Forearm Fracture

Denmark
Nordsjaellands Hospital

Recruiting

Ultrasound-guided Infraclavicular Block With Lidocaine or Ropivacaine for Closed Reduction of Distal Radius Fractures

Colles' Fracture | Fracture Dislocation | Distal Radius Fractures | Lidocaine | Ropivacaine | Closed Reduction of Fracture and Application of Plaster Cast

Denmark
Modern Biosciences Ltd

Recruiting

Drug-Drug Interaction (DDI) Study of Leramistat in Healthy Adult Subjects

Pharmacokinetics

United Kingdom
Teoxane SA

Not yet recruiting

RHA® Redensity With New Anesthetic Agent Perioral Rhytids (PAS)

Pain | Aging

United States
Amany Ahmed Eissa

Recruiting

The Efficacy of Thoracic Erector Spinae Plane Block For Perioperative Analgesia in Laparoscopic Bariatric Surgery for Super Obese Patients: Randomized Controlled Trial.

Erector Spinae Plane Block | Bariatric Surgery | Super Obese Patients

Egypt
Galderma R&D

Not yet recruiting

Comparing Pain, Safety and Effectiveness of Restylane Skinboosters Vital Lido and Vital Without Lido in Dorsal Hand

Skin Aging of Dorsal Hands

China
Kasr El Aini Hospital

Recruiting

Evaluation of Lidocaine Spray Versus Dexmetomidine Spray on Stress Response

To Measure Systolic Blood Pressure Postintubation

Egypt
Babujinaya Cela

Not yet recruiting

Effect of Stellate Ganglion Block on Drooling in Parkinson's Syndrome

Parkinson's Syndrome
Ain Shams University

Recruiting

Assessment Of Dose-Dependent Immunomodulatory Effect Of Alveofact With or Without Steroisd In Neonatal RDS

Inflammatory Response | Preterm Birth | Premature Lungs | Neonatal Respiratory Distress Syndrome | Neutrophil Extracellular Trap Formation

Egypt
Prince of Songkla University

Not yet recruiting

Short Effects of SIMT and EM in Prolonged Mechanically Ventilated Patients

Ventilator Dependent

Thailand
Editas Medicine, Inc.

Not yet recruiting

A Long-Term Follow-Up Study of Participants With Sickle Cell Disease or Transfusion Dependent β-Thalassemia Who Received EDIT-301

Sickle Cell Disease | Hemoglobinopathies | Transfusion-dependent Beta-Thalassemia
Ain Shams University

Recruiting

Analgesic Effect of Illiohypogastic & Ilioinguinal Nerve Block in TAVR - TF (Prospective Randomized Study)

Anesthesia, Local

Egypt
Krankenhaus Barmherzige Schwestern Linz

Not yet recruiting

VENLID: The Application of a 10%-Lidocaine Spray Prior to the Insertion of a Peripheral Intra-venous Catheter in Female Adults (VENLID)

Pain
Istituto di Fisiologia Clinica CNR

Not yet recruiting

Use of ETElcalcetidefor pReserving vitamiN K-dependent proteIn activiTY ITAlian Study (ETERNITY-ITA)

Hemodialysis
Johns Hopkins University
National Institute on Drug Abuse (NIDA)

Not yet recruiting

Examining the Role of Tolerance on Dose-dependent Effects of Acute THC on Oculomotor and Cognitive Performance

Cognitive Impairment | Cannabis Use | Impaired Driving

United States
Hans Bahlmann
Linkoeping University

Recruiting

Spinal Morphine or Intravenous Lidocaine in Robot-assisted Upper Urologic Surgery (SMILe)

Renal Cancer | Ureter Cancer | Other Specified Disorders of Kidney and Ureter | Benign Neoplasm of Ureter | Calculus of Kidney and Ureter | Ureteric Reflux | Congenital Ureteric Anomaly | Benign Renal Neoplasm

Sweden
Ain Shams University

Not yet recruiting

Quality of Recovery After Laparoscopic Cholecystectomy Comparing Opioid Free Analgesia Versus Opioid Free Anesthesia

Pain, Postoperative | Quality of Recovery | Elective Laparoscopic Cholecystectomy

Egypt
IRCCS Policlinico S. Matteo

Not yet recruiting

Sciatic Nerve Block for Ankle and Leg Fracture Manipulation in the Emergency Department (AnkleMan)

Ankle Fractures | Leg Fracture

Italy
Copka Sonpashan

Not yet recruiting

Intra-articular Injection Versus Normal Rehabilitation Therapy on Temporomandibular Joint Dysfunction

Temporomandibular Joint Dysfunction
Copka Sonpashan

Not yet recruiting

Impact of Glossopharyngeal Nerve Block on Swallowing Difficulties Caused by Gastroesophageal Reflux Disease

Dysphagia
University of Salamanca

Not yet recruiting

Interdisciplinary Psychoeducational Intervention Programme for Caregivers of Dependent Older Adults

Occupational Therapy | Intervention | Family Caregiver | Psychology | Dependent Older People | Interdisciplinary | Psychoeducational

Spain
Copka Sonpashan

Not yet recruiting

Stellate Ganglion Block in Bulbar Palsy

Bulbar Palsy
Copka Sonpashan

Not yet recruiting

Stellate Ganglion Block on Gastroesophageal Reflux Disease

Gastroesophageal Reflux Disease
Copka Sonpashan

Not yet recruiting

Effectiveness of Stellate Ganglion Block in Patients Diagnosed With Parkinson's Disease

Parkinson Disease
Copka Sonpashan

Not yet recruiting

Stellate Ganglion Block in Children With Autistic Disorder

Autistic Disorder
Copka Sonpashan

Not yet recruiting

Stellate Ganglion Block in Cerebral Palsy

Cerebral Palsy
Copka Sonpashan

Not yet recruiting

Effectiveness of Stellate Ganglion Block for the Treatment of Obstructive Sleep Apnea

Obstructive Sleep Apnea

Search clinical trials for: Non-transfusion dependent

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