Search clinical trials for: PARPi resistance

Total 7025 results

National Cancer Institute (NCI)

Recruiting

A Phase I/II Study of Sacituzumab Govitecan Plus Berzosertib in Small Cell Lung Cancer, Extra-Pulmonary Small Cell Neuroendocrine Cancer and Homologous Recombination-Deficient Cancers Resistant to PARP Inhibitors

Advanced Solid Tumors | SCLC | HRD Cancer

United States
Xing Xie

Recruiting

Fuzuloparib Arsenic Trioxide Platinum Resistance Relapsed Ovarian Cancer

Efficacy and Safety

China
Central South University

Not yet recruiting

Investigating the Insulin Resistance in Individuals With Type 2 Diabetes

Type 2 Diabetes

China
Khyber Medical University Peshawar

Recruiting

Impact of FTO Gene Variation on Body Composition, Lipid Profile, Insulin Resistance, Advanced Glycation End-Products and Ghrelin Levels in Response to Hypocaloric, Protein Rich-Diet

Inflammation | Obesity | Insulin Resistance | Dyslipidemias | Advance Glycation

Pakistan
University of Sao Paulo General Hospital
Conselho Nacional de Desenvolvimento Científico e Tecnológico

Not yet recruiting

Effect of Resistance Training in Patients on the Waiting List for Heart Transplant

Heart Failure | Heart Transplant

Brazil
Georgiamune Inc

Not yet recruiting

Safety and Tolerability Study of GIM-531 in Advanced Solid Tumors

Solid Tumor | Melanoma Stage IV
Universidade Federal do Rio Grande do Norte

Not yet recruiting

Preference of Women With Fibromyalgia Undergoing a Three Different Volumes of Resistance Training

Chronic Pain | Exercise Addiction | Fibromyalgia, Primary

Brazil
H. Lee Moffitt Cancer Center and Research Institute

Recruiting

Remote Exercise and Nutritional Prehabilitation for Pancreatic Cancer

Pancreatic Cancer

United States
University of California, San Francisco
National Institute of Allergy and Infectious Diseases (NIAID); University of... and other collaborators

Not yet recruiting

Randomized Trial to Optimize Virologic Suppression Rates Using a Point-of-Care Urine Monitoring Assay (ROVING PUMA) (ROVING-PUMA)

ART Adherence

South Africa
University of South Carolina

Recruiting

Resistance Exercise and Creatine in Colorectal Cancer

Colorectal Cancer

United States
University of Udine

Recruiting

Salivary microRNA in Endometriosis: Correlation With Response to Progestin Therapy (ENDOmiRNA)

Endometriosis

Italy
Children's Hospital of Fudan University

Not yet recruiting

High-Intensity Interval Training(HIIT) on Cardio-metabolic Risk in School-age Children

Cardiovascular Syndrome, Metabolic
Brooklyn Clinical Research

Not yet recruiting

Triage Survey for Cardiovascular, Obesity, and Related Endocrine Trial Eligibility (SWIFT-CORE-101)

Cardiovascular Diseases | Obesity | Metabolic Syndrome | PreDiabetes | Diabetes Type 2

United States
Pakistan Society for Rehabilitation of Differently...
University of Karachi

Recruiting

Adaptive Response of Brain Towards Resistance Training in Healthy Individuals

Resistance Training

Pakistan
Regeneron Pharmaceuticals

Not yet recruiting

A First-In Human (FIH) Trial to Find Out if REGN10597 is Safe and How Well it Works for Adult Participants With Advanced Solid Organ Malignancies

Melanoma | Advanced Solid Tumors | Clear-Cell Renal-Cell Carcinoma (ccRCC)
Jordan Collaborating Cardiology Group
Cardiovascular Academy; The Association of Jordanian Medical Laboratory Specialists...

Not yet recruiting

The Cardiovascular-Renal-Metabolic (CRM) Syndrome Survey in Jordan (JoCRMSSurvey)

Cardiovascular-renal-metabolic Syndrome

Jordan
Beneficência Portuguesa de São Paulo
Ministry of Health, Brazil

Not yet recruiting

Effect of a Bundle of Interventions on the Outcomes of Patients With Intracranial Devices (ICP Monitor e EVD)

Central Nervous System Infections
University Medical Center, Kazakhstan
Nazarbayev University; Astana Medical University; Ministry of Science and Higher... and other collaborators

Recruiting

Effectiveness of Weight Loss Methods on Lifespan for Metabolic Syndrome

Metabolic Syndrome

Kazakhstan
Riphah International University

Not yet recruiting

Comparison of High Intensity Strength Training and Muscle Energy Techniques in TKR Patients

Knee Osteoarthritis | Resistance Training | Arthroplasty, Knee Replacement

Pakistan
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Choroid Plexus Dysfunction in Neurological Diseases (PLEXFOLD)

Metabolic Syndrome | Plexus Choroideus

France
TOLREMO therapeutics AG

Recruiting

A Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Efficacy of TT125-802 in Subjects With Advanced Solid Tumors (TT-CSP-001)

Cancer | Adult Solid Tumor | Advanced Solid Tumor | Adult Disease

Spain, Switzerland
Maastricht University Medical Center
Cargill

Not yet recruiting

Plant Protein Blend and Milk Protein Supplements in Older Individuals (Blend-D2O)

Sarcopenia | Skeletal Muscle Atrophy | Protein Malnutrition
National University of Singapore
National University Polyclinics, Singapore

Not yet recruiting

Intensive Aerobic and Resistance Exercise Program (IAREP)

Type 2 Diabetes Mellitus | Cognitive Impairment | Cognitive Dysfunction | Non-insulin-dependent Diabetes Mellitus
Mayo Clinic
Temple University

Recruiting

Extracellular Vesicle Cargo in Obesity and Type 2 Diabetes

Diabetes | Insulin Resistance | Glucose Intolerance

United States
Assiut University

Not yet recruiting

Insulin Resistance in Relation to Hyperthyroidism and Hypothyroidism

Insulin Resistance
Assiut University

Not yet recruiting

Clinical and Laboratory Evaluation of Antifungal Resistance in Tinea Capitis

Fungal Resistance
Milton S. Hershey Medical Center
National Institute on Aging (NIA)

Not yet recruiting

Impact of Brief Daily Functional Resistance Training on Lower Extremity Physical Performance (FASTNIA)

Mobility Limitation
Maastricht University Medical Center

Not yet recruiting

Effects of Ketone Monoesters on Brain Function

Cerebral Blood Flow | Cognitive Performance | Appetite Control | Brain Vascular Function | Brain Insulin Sensitivity

Netherlands
Korea University Anam Hospital
Korean Society of Hypertension

Recruiting

Home Blood Pressure Variability and Its Link to Arteriosclerosis and Metabolic Dysfunction in Hypertensive Patients

Arteriosclerosis | Hypertension | Metabolic Syndrome X | Blood Pressure Monitoring, Home

Korea, Republic of
Erasme University Hospital

Not yet recruiting

Investigating Brain Insulin Resistance In Alzheimer Disease With IntraNasal Insulin : A Multimodal Neuroimaging Study (Memori³)

Alzheimer Disease | Mild Cognitive Impairment
Xiaojun Chen

Recruiting

GnRHa + Letrozole in Obese Progestin-insensitive Endometrial Atypical Hyperplasia Patients

Obesity | Atypical Endometrial Hyperplasia | Progesterone Resistance

China
Abderrahmane Mami Hospital

Recruiting

Epidemiological Features of Emergent Highly Resistant Bacteria in Tunisian Intensive Care Units (NOSOREA3)

Critical Illness | Cross Infection | Vancomycin-Resistant Enterococcal Infection | Carbapenem Resistant Bacterial Infection

Tunisia
Cairo University

Not yet recruiting

Composite Repair Using Silane Coupling Agent

Hypersensitivity | Tooth Discoloration | Dental Restoration Failure of Marginal Integrity | Tooth Fracture
New Valley University

Not yet recruiting

Characterizing Diversity and Antifungal Resistance in Immunocompromised ICU Patients With Respiratory Tract Infections

Immunocompromised ICU Patients With Respiratory Tract Infections
Cairo University

Not yet recruiting

Antibiotic Use and Resistance KAP Among Dental Interns

Antibiotic Side Effect | Antibiotic Resistant Infection
Xiaojun Chen

Recruiting

GnRHa + Letrozole in Obese Progestin-insensitive Endometrial Cancer Patients

Obesity | Atypical Endometrial Hyperplasia | Endometrial Neoplasms | Progesterone Resistance

China
Riphah International University

Recruiting

Comparison of Aerobic and Resistance Training on Exercise Capacity, Depression and Quality of Life in Hypothyroidism.

Comparison of Aerobic Exercise and Resistance Training

Pakistan
Badr University

Not yet recruiting

High Intensity Interval Versus Focused Ultrasound on Insulin Resistance in Diabetics With Abdominal Obesity (diabetic)

Diabetes | Insulin Resistance | Abdominal Obesity
University of Nottingham
Biotechnology and Biological Sciences Research Council

Recruiting

Multi-organ Responses to CHronic Physical Activity and INactivity (CHAIN)

Metabolic Syndrome | Sedentary Behavior | Age-related Cognitive Decline | Age-Related Sarcopenia

United Kingdom
Shenzhen Institute of Advanced Technology, Chinese...

Not yet recruiting

The Associations Between Gut Length, Gut Microbiota and Food Assimilation

Food Preferences | Healthy Nutrition | Metabolic Syndrome, Protection Against

China
Stanford University

Not yet recruiting

Stronger: Muscle Strengthening for Menopause

Resistance Training

United States
University of Missouri-Columbia
Gilead Sciences

Recruiting

Accelerated ART Initiation for PWHIV Who Are Out of Care (ACCELERATE)

HIV Infections | ART | Noncompliance, Patient

United States
Shanghai Zhongshan Hospital

Not yet recruiting

Resistance Swallowing Training in Patients With Tracheotomy

Swallowing Training on Muscle Strength
University of Aarhus
Aarhus University Hospital; University of Copenhagen

Not yet recruiting

Resistance Training and Corticospinal Excitability in Multiple Sclerosis (NEXIMS)

Multiple Sclerosis
Cairo University

Not yet recruiting

Antibiotics, Antibiotic Resistance, and Prescribing Practices Among Periodontists: Cross Sectional KAP Study

Periodontitis | Antibiotic Resistance | Antibiotic Use
Region Skane
Lund University

Not yet recruiting

Screening of Multidrug Resistant Bacteria, and the Clinical Implication for the Patient

Multi-antibiotic Resistance
Lawson Health Research Institute
Greenstone Biosciences, Inc.

Not yet recruiting

iPSC Biobank of Biomarkers Diversity in Cardiovascular Disease (INFERENCE)

Cardiovascular Diseases | Heart Failure | Cardiomyopathies | Congenital Heart Disease | Cerebrovascular Accident | Arrythmia | Cardiometabolic Syndrome
Universidad de La Frontera

Not yet recruiting

Resistance Exercise Training in the Older Population With Obesity (RETOPO)

Obesity | Aging

Chile
University of Utah

Recruiting

The Acute T-Rex (Timing of Resistance Exercise) Study

Diabetes Mellitus, Type 2 | Insulin Resistance | Glucose Intolerance | Sleep Disturbance | Overweight or Obesity | Insulin Sensitivity

United States
Medical College of Wisconsin

Not yet recruiting

Molecular Analyses to Identify Pathways of Endocrine Resistance Following Short Term Neoadjuvant Endocrine Treatment in Patients With Hormone Receptor-Positive HER2-negative Breast Cancer

Breast Cancer

United States

Search clinical trials for: PARPi resistance

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