Search clinical trials for: PF-04965842

Total 1604 results

Pfizer

Completed

A Study to Determine the Effects of PF-04965842 on the Pharmacokinetics of Oral Contraceptive Steroids in Healthy Female Subjects

Healthy Females

United States
Pfizer

Completed

A Study to Determine the Effects of PF-04965842 on Midazolam PK in Healthy Volunteers

Phase 1

Belgium
Pfizer

Completed

AStudy to Evaluate the Bioavailability of PF 04965842 in Healthy Subjects

Healthy

Belgium
Pfizer

Completed

Study to Investigate Efficacy and Safety of PF-04965842 in Subjects Aged 12 Years and Over With Moderate to Severe Atopic Dermatitis With the Option of Rescue Treatment in Flaring Subjects

Skin Diseases | Immune System Diseases | Hypersensitivity | Hypersensitivity, Immediate | Genetic Diseases, Inborn | Skin Diseases, Genetic | Dermatitis | Eczema | Skin Diseases, Eczematous | Dermatitis, Atopic

United States, Spain, Taiwan, Germany, Canada, China, Poland, Belgium, Serbia, Brazil, Russian Federation, Israel, Latvia, Italy, Romania, Mexico, Argentina, Bulgaria, Chile, Netherlands, Slovakia
Pfizer

Completed

Study Evaluating the Mechanism of Action of PF-04965842 Monotherapy for Moderate-to-severe Atopic Dermatitis (JADE MOA)

Atopic Dermatitis

United States, Canada
Pfizer

Completed

Study Evaluating Efficacy and Safety of PF-04965842 in Subjects Aged 12 Years And Older With Moderate to Severe Atopic Dermatitis (JADE Mono-2)

Dermatitis, Atopic

China, United States, Australia, Poland, Hungary, Korea, Republic of, Germany, Bulgaria, Canada, Czechia, Japan, Latvia, United Kingdom
Pfizer

Completed

Study to Evaluate Efficacy and Safety of PF-04965842 in Subjects Aged 12 Years And Older With Moderate to Severe Atopic Dermatitis (JADE Mono-1)

Dermatitis, Atopic

United States, Hungary, Canada, Germany, Australia, Czechia, Poland, United Kingdom
Pfizer

Completed

Study Evaluating Efficacy and Safety of PF-04965842 and Dupilumab in Adult Subjects With Moderate to Severe Atopic Dermatitis on Background Topical Therapy (JADE Compare)

Skin Diseases | Immune System Diseases | Hypersensitivity | Hypersensitivity, Immediate | Genetic Diseases, Inborn | Skin Diseases, Genetic | Dermatitis | Eczema | Skin Diseases, Eczematous | Dermatitis, Atopic

Spain, Taiwan, United States, Australia, Poland, Germany, Hungary, Bulgaria, Czechia, Japan, Korea, Republic of, Latvia, Canada, United Kingdom, Mexico, Chile, Slovakia, Italy
Pfizer

Completed

A Hepatic Impairment Study for PF-04965842.

Hepatic Impairment

United States
Pfizer

Completed

A Renal Impairment Study for PF-04965842

Renal Impairment

United States, Belgium
Pfizer
In Expanded Access, treating physicians are the Sponsor

Available

Pre-approval Single-patient Expanded Access for Abrocitinib (PF-04965842)

Severe Uncontrolled Atopic Dermatitis
Pfizer

Completed

Drug Drug Interaction Study Evaluating the Effect of Fluvoxamine or Fluconazole on PK and Safety of PF-04965842.

Dermatitis, Atopic

Belgium
Pfizer

Completed

Study of PF-04965842 Effect on Dabigatran Pharmacokinetics in Healthy Participants

Healthy

Belgium
Pfizer

Completed

Study of PF-04965842 Effect on Rosuvastatin Pharmacokinetics in Healthy Participants

Healthy

Belgium
Pfizer

Completed

Study of PF 04965842 Effect on MATE1/2K Activity in Healthy Participants

Healthy

Belgium
Pfizer

Completed

JAK1 Inhibitor With Medicated Topical Therapy in Adolescents With Atopic Dermatitis (JADE TEEN)

Atopic Dermatitis

Spain, United States, Taiwan, Germany, China, Hungary, Australia, Czechia, Japan, Latvia, Poland, United Kingdom, Mexico, Italy
Pfizer

Completed

Study To Evaluate Pf-04965842 In Subjects With Moderate To Severe Atopic Dermatitis

Atopic Dermatitis

United States, Canada, Australia, Germany, Hungary
Pfizer

Terminated

Study to Evaluate PF-04965842 in Patients With Moderate to Severe Psoriasis

Plaque Psoriasis

United States, Canada
Assiut University

Not yet recruiting

Intrapartum Ultrasonography in Evaluation of the Progress of Labor

Progress pf Labor
Children's Hospital of Philadelphia
National Library of Medicine (NLM)

Completed

Comprehensive Clinical Decision Support (CDS) for the Primary Care of Premature Infants (PreemieCDS)

Prematurity

United States
Hospices Civils de Lyon

Recruiting

Evaluation of a Management Strategy for Second-degree Fibrinous Burns Integrating a Poly-absorbent Dressing (HYDRA-B)

Burns Degree Second

France
Pfizer

Completed

A Study To Determine The Effect Of Single-dose PF-04965842 On QTc Interval In Healthy Volunteers Compared With Placebo and Moxifloxacin

Healthy Volunteers

Belgium
Prince of Songkla University

Active, not recruiting

Gastric Volume After Ingestion of Carbohydrate Drink vs Water in Obese Volunteers

Obesity | Gastric Emptying

Thailand
Pfizer

Completed

First-in-Human Study to Evaluate Safety and Tolerability of Single and Multiple Ascending Doses of Janus Kinase-1 Inhibitor PF-04965842 in Healthy Western and Japanese Subjects

Healthy

United States
Olympus Biotech Corporation

Completed

The TRAfermin in Neuropathic Diabetic Foot Ulcer Study - Northern Europe The TRANS-North Study (TRANS-North)

Diabetic Foot Ulcer of Neuropathic Origin

Belgium, Germany, Poland, Croatia, Bulgaria, Denmark, Slovakia, Hungary, Netherlands, Sweden
Skingenix, Inc.

Recruiting

Phase 2 Pilot Study of the Safety and Efficacy of Topical MW-III in Thermal Burns

Burns

United States
Pfizer

Completed

Study to Assess Pharmacokinetics, Safety and Tolerability of PF-04965842 in Chinese Healthy Participants

HEALTHY

China
Pfizer

Completed

A Study to Assess Pharmacokinetics of PF-04965842 and Its Metabolites and Effect of Probenecid in Healthy Participants

Healthy

United States
Pfizer

Completed

Absorption, Metabolism, Excretion and Absolute Bioavailability

Healthy

Netherlands
Pfizer

Completed

Drug Interaction Study Evaluating the Effect of Rifampin on PK and Safety of PF 04965842.

Healthy

Belgium
MTI University

Unknown

Triceps Taping on Elbow Flexion Tightness in Extended Erb's Palsy

Deformity Flexion

Egypt
Karen-Lise Garm Spindler
Zealand University Hospital; Vejle Hospital

Recruiting

OPTIMIzation of Treatment SElection and Follow up in Oligometastatic Colorectal Cancer (OPTIMISE)

Colorectal Cancer | Metastatic Cancer

Denmark
Pfizer

Completed

Study of Commercial and Phase 3 of PF-04965842 Formulations, Estimation of Effect of Food on Commercial Formulation

Dermatitis, Atopic

United States
Seoul National University Hospital

Unknown

Predictive Model for Postoperative Complications in Hemi-hip Arthroplasty

Arthroplasty | Complication | Risk Factor | Elderly Patient

Korea, Republic of
Seoul National University Hospital

Unknown

The Recovery Profiles After Robotic or Open Thyroidectomy

Postoperative Pain | Postoperative Sorethroat

Korea, Republic of
Seoul National University Hospital

Recruiting

Registry for Degenerative Spinal Disease (RDSD) (RDSD)

Surgery | Degeneration Spine

Korea, Republic of
Chung-Ang University Gwangmyeong Hospital

Not yet recruiting

Comparison of Remimazolam and Propofol Combination vs. Propofol in IOM

Neurologic Disorder
HaEmek Medical Center, Israel

Unknown

Safety and Tolerability of Herpes Zoster Vaccine Rheumatologic Patients

Herpes Zoster

Israel
Chinese PLA General Hospital
Gansu Provincial Maternity and Child-Care Hospital

Unknown

Mesenchymal Stem Cell-derived Pleiotropic Factor in Treating Poorly Healed Wounds of Postoperative Incision

MSCs-PFs in Treating Poorly Healed Wounds of Postoperative Incision
Samsung Medical Center

Unknown

Iressa for EGFR Mutation Negative Non-small Cell Lung Cancer (NSCLC)

Nonsmall Cell Lung Cancer

Korea, Republic of
Samsung Medical Center

Unknown

Weekly Docetaxel Plus Cisplatin as the First-line Therapy for Nasopharyngeal Cancer

Nasopharyngeal Cancer

Korea, Republic of
Samsung Medical Center

Unknown

Chemotherapy With or Without Radiosurgery for Asymptomatic Oligo Brain Metastasis

Nonsmall Cell Lung Cancer

Korea, Republic of
Pfizer

Completed

A Study to Understand the Effect of Tablet Formulation and Food on PF-06821497 in Healthy Adult Participants.

Healthy

United States
Pfizer

Completed

A Drug-Drug Interaction Study Between PF-06882961 and PF-06865571 in Healthy Adult Participants and Overweight Adults or Adults With Obesity Who Are Otherwise Healthy

Healthy Volunteer

United States
Pfizer

Not yet recruiting

A Study to Learn How the Medicine Called [14C] PF-06821497 is Taken up Into and Removed From the Body.

Healthy Participants
Pfizer

Completed

A Study To Assess The Safety Of PF-06342674 In Adults With Type 1 Diabetes

Diabetes Mellitus, Type 1

United States
University College Dublin

Completed

Video- Or Direct Laryngoscopy for Endotracheal Intubation in Newborns (VODE)

Intubation, Intratracheal | Infant, Newborn | Laryngoscopes

Ireland
Pfizer

Completed

A Study to Understand How the Study Medicine (PF-07081532) is Processed and Eliminated in Healthy Men

Healthy Participants

Netherlands
Pfizer

Completed

To Calculate the Pharmacokinetics (Concentration of Compound in and Rate of Excretion From the Blood) Following a Very Low Dose of Compound Which Will Not Have Any Pharmacological Activity

Healthy

United Kingdom
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Comparing PI-Based to a nNRTI-based ART for Clearance of Plasmodium Falciparum Parasitemia in HIV-Infected

HIV-1 Infection | Pf Subclinical Parasitemia

Kenya, Malawi, Uganda

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