Search clinical trials for: PK

Total 3473 results

DemeRx NB

Not yet recruiting

Multiple Ascending Dose Noribogaine PK/PD in Healthy Volunteers

Pharmacokinetics
Peking University People's Hospital

Recruiting

Antibiotic Exposure During Pregnancy Affects Infant Gut Microbiota

Antibiotics Affecting Newborn Gut Microbiota

China
Peking University People's Hospital

Recruiting

Interactions Between Environmental Exposures and Gut Microbiota in Early Life

Infant Development

China
KalVista Pharmaceuticals, Ltd.

Not yet recruiting

Open-Label Safety, PK, and Efficacy Trial of Sebetralstat (KVD900) in Pediatric Patients (Ages 2-11) With HAE Type I or II (KONFIDENT-KID)

Hereditary Angioedema
Genentech, Inc.

Recruiting

A Study to Evaluate the Effect of Injection Site on PK of Astegolimab in Healthy Subjects

Healthy Volunteers

United States
Chengdu Baiyu Pharmaceutical Co., Ltd.

Recruiting

A Phase l Study of By101298, an Oral DNA-PK Inhibitor, in Patients With Advanced Solid Tumors

Solid Tumor, Adult

China
Il-Yang Pharm. Co., Ltd.

Not yet recruiting

Clinical Trial to Investigate the Effects of Food on the Pharmacokinetics and Safety of Orally Administered Radotinib

Drug Kinetics

Korea, Republic of
MDI Therapeutics, Inc.

Recruiting

SAD Evaluation of Safety, Tolerability, PK, and PD of MDI-2517 in Healthy Participants

Safety and Tolerability

United States
University of Hamburg-Eppendorf

Not yet recruiting

Model-informed Precision Dosing for Linezolid (LINEMAP)

Gram-Positive Bacterial Infections
Peking University Cancer Hospital & Institute

Not yet recruiting

Neoadjuvant Fruquintinib Plus Tislelizumab Combined With mCapeOX Versus CapeOX for Mid-high pMMR/MSS Locally Advanced Rectal Cancer (PKUCH-R09)

Rectal Cancer

China
Pakistan Institute of Living and Learning
Fatima Jinnah Women University

Not yet recruiting

Universally Delivered Interventions for Young People (Mindset-PK)

Distress, Emotional

Pakistan
Riphah International University

Recruiting

Additional Effects of Quranic Listening Meditation in Combination With High Intensity Interval Training in Obese Adults

Obesity

Pakistan
ITM Solucin GmbH

Not yet recruiting

Phase I Trial to Determine the Dose and Evaluate the PK of Lutetium Lu 177 Edotreotide Therapy in Pediatric Participants With SSTR-positive Tumors (KinLET)

Lymphoma | CNS Tumor | Solid Tumor, Childhood | Somatostatin Receptor Positive | NET
Nanexa AB
Profil Institut für Stoffwechselforschung GmbH

Not yet recruiting

Phase 1 Study Assessing the Pharmacokinetics of NEX-22A in Subjects With T2D

Type 2 Diabetes
Peking University First Hospital
Peking University Third Hospital; Peking University Cancer Hospital & Institute

Recruiting

A Study of Molecular Subtyping-based Therapeutic Strategies for Cutaneous T-cell Lymphoma (AMITY)

Cutaneous T Cell Lymphoma | Cutaneous T-Cell Lymphoma/Mycosis Fungoides

China
GlaxoSmithKline

Not yet recruiting

A Study to Compare the Pharmacokinetics (PK) of Salbutamol Administered Via Metered Dose Inhalers (MDI) Containing Propellants HFA-152A (Test) or HFA-134A (Reference) in Healthy Participants Aged 18 to 55 Inclusive

Asthma | Healthy Participants

Netherlands
JW Pharmaceutical

Not yet recruiting

PK,PD and DDI of Epaminurad and Naproxen in Healthy Volunteers

Healthy

Korea, Republic of
Ironshore Pharmaceuticals and Development, Inc

Not yet recruiting

Ph3 Multicenter, 3wk RDBPC Efficacy, Safety & PK Study of Evening Dosed MPH HCl ER Capsules (HLD200) in Children 4-5 Yr With ADHD

Attention Deficit Hyperactivity Disorder
Bostal Drug Delivery Co., Ltd

Not yet recruiting

A Study to Evaluate Safety, Tolerability and pK of Semaglutide ER Injectable Suspension in Healthy, Adult Human Subjects

Diabetes Mellitus, Type 2
Q32 Bio Inc.

Not yet recruiting

A Phase 2 Study to Evaluate the Safety, PD, PK, and Clinical Activity of ADX-097 in Participants With IgAN, LN or C3G

IgA Nephropathy | Lupus Nephritis (LN) | C3 (Complement Component 3) Glomerulopathy
Universidad del Desarrollo
Technical University of Munich

Recruiting

Re-evaluation of the Effect Site Model of the PKPD Propofol Eleveld Model (Eleved PD)

Healthy | Surgery

Chile
Novartis Pharmaceuticals

Not yet recruiting

Pharmacokinetics Study of Ianalumab in Chinese Participants With Autoimmune Diseases

Systemic Lupus Erythematosus | Sjogren Disease
Riphah International University

Not yet recruiting

Effects of Functional Progressive Strength Training in Children With Spastic Cerebral Palsy

Spastic Cerebral Palsy

Pakistan
Peking University First Hospital

Not yet recruiting

Effect of OSA Resulting From Chronic Tonsillitis on Pregnancy Outcomes

Obstructive Sleep Apnea | Pregnancy | Chronic Tonsillitis
Dong-A ST Co., Ltd.

Not yet recruiting

A Study to Evaluate Safety, Tolerability, and PK of DA-7503 in Healthy Adult and Elderly Participants

Healthy

Korea, Republic of
Peking University First Hospital

Not yet recruiting

The Effect of OSA on Pregnancy and Fetal Outcomes

Obstructive Sleep Apnea | Pregnancy
Alto Neuroscience

Recruiting

PD, PK, and Safety of ALTO-203 in Patients With MDD

Anhedonia | Major Depressive Disorder

United States
Hannover Medical School
Boehringer Ingelheim

Recruiting

Study of Empagliflozin in Patients With Autosomal Dominant Polycystic Kidney Disease (EMPA-PKD) (EMPA-PKD)

Autosomal Dominant Polycystic Kidney

Germany
Assembly Biosciences

Recruiting

A Study to Assess the Safety, Pharmacokinetics, and Antiviral Activity of ABI-5366 in Healthy Participants and Participants Seropositive for HSV-2 With Recurrent Genital Herpes

Recurrent Genital Herpes Simplex Type 2

New Zealand
Suzhou Suncadia Biopharmaceuticals Co., Ltd.

Recruiting

PK/PD Study of SHR-2017 Injection in Patients With Bone Metastases

Patients With Bone Metastases

China
The Seventh Affiliated Hospital of Sun Yat-sen...
Huizhou Municipal Central Hospital; Dongguan Hospital of Traditional Chinese... and other collaborators

Recruiting

Development and Validation of a Postoperative Re-fracture Risk Model for Osteoporotic Spinal Fractures

Osteoporosis Fracture | Compression Fracture | Osteoporosis Vertebral | Perform PVP / PKP Treatment

China
Peking University Hospital of Stomatology

Recruiting

Clinical Evaluation of Polycation-based New Dental Desensitizer on Dentin Hypersensitivity

Dentin Sensitivity

China
Eilean Therapeutics

Not yet recruiting

Dose Escalation and Expansion Study to Evaluate the Safety, PK, PD and Efficacy of ZE46-0134 in Adults With FLT3 Mutated Relapsed or Refractory Acute Myeloid Leukemia

AML With Gene Mutations

Australia
OncoC4, Inc.

Not yet recruiting

Safety, Pharmacokinetics (PK), and Efficacy of ONC 841 in Advanced Solid Tumors

Advanced Solid Tumor

United States
Haisco Pharmaceutical Group Co., Ltd.

Recruiting

A Phase I Study to Assess the Safety,Tolerability, PK, PD, and Food Effect of HSK39297 in Healthy Subjects

Healthy

China
ReAlta Life Sciences, Inc.

Not yet recruiting

Safety, PK, PD, Dosing, and Efficacy of RLS-0071for the Treatment of Hospitalized Patients With Steroid-Refractory Acute Graft-versus-Host Disease (AURORA)

Steroid Refractory GVHD
Vertex Pharmaceuticals Incorporated

Recruiting

A Phase 1 Study to Evaluate Safety, Tolerability, and Pharmacokinetics (PK) of VX-407 in Healthy Participants

Autosomal Dominant Polycystic Kidney Disease (ADPKD)

United States
Peking University People's Hospital
Peking University Shougang Hospital; Shandong Cancer Hospital and Institute

Recruiting

Weekly Irinotecan Liposomes in Recurrent or Refractory Ewing Sarcoma

Ewing Sarcoma

China
Rigshospitalet, Denmark

Not yet recruiting

Evaluating the Efficacy and Safety of Large Neutral Amino Acids in the Treatment of Classical Phenylketonuria

Brain Diseases | Genetic Diseases, Inborn | Metabolism, Inborn Errors | Brain Diseases, Metabolic | Phenylketonurias | Brain Diseases, Metabolic, Inborn | Amino Acid Metabolism, Inborn Errors | Metabolic Disease

Denmark
NGGT INC.

Not yet recruiting

AAV Gene Therapy Clinical Study in Adult Classic PKU

Phenylketonurias
Hartford Hospital
Melinta Therapeutics, LLC

Not yet recruiting

Rezafungin PK in Patients on ECMO

Sepsis

United States
Academisch Medisch Centrum - Universiteit van Amsterdam...
ZonMw: The Netherlands Organisation for Health Research and Development

Not yet recruiting

Effect and Process Evaluation of the SME Tool

Sick-listed Employees
The Third Xiangya Hospital of Central South University

Not yet recruiting

PK/PD Study of Anti-Infective Drugs in Critically Ill Patients Receiving Extracorporeal Membrane Oxygenation Treatment (ECMO)

Critical Illness | Extracorporeal Membrane Oxygenation Complication

China
Kathelijn Fischer
Radboud University Medical Center; University Medical Center Groningen; Maastricht... and other collaborators

Recruiting

Pharmacokinetic-guided Dosing of Emicizumab (DosEmi)

Adolescent | Child | Hemophilia A With Inhibitor | Adult | Hemophilia A Without Inhibitor | Hemophilia A, Severe

Netherlands
Teva Branded Pharmaceutical Products R&D, Inc.

Recruiting

Open-label Trial Characterizing the PK of 3 SC Olanzapine Extended-release Formulations in Participants With Schizophrenia/Schizoaffective Disorder

Schizophrenia, Schizoaffective Disorder

United States
Advanced Education & Research Center
University of Karachi; Pakistan Cardiac Society (Heart House)

Recruiting

Prospective Assessment of Atherosclerotic Cardiovascular Disease (ASCVD) Risk

Atherosclerotic Cardiovascular Diseases (ASCVD)

Pakistan
Suzhou Genhouse Bio Co., Ltd.
Shanghai East Hospital; Shandong Tumor Hospital

Recruiting

A Phase I/II Clinical Study to Evaluate The Safety, PK, PD of GH55 in Patients With MAPK Mutant Advanced Solid Tumors

Advanced Solid Tumors With MAPK Signal Pathway Mutant

China
Tenaya Therapeutics
Medical University of South Carolina; Johns Hopkins University; University of... and other collaborators

Recruiting

Non-interventional Study of Seroprevalence of Pre-existing Antibodies Against Adenovirus-associated Virus Vector (AAV9) and the Progression of Disease in Patients With Plakophilin 2 (PKP2)-Associated Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) (RIDGE)

Arrhythmogenic Right Ventricular Cardiomyopathy

United States, France, Italy, United Kingdom, Sweden, Germany
BioMarin Pharmaceutical

Recruiting

A Long Term, Post-marketing Study of Immune Response in Patients Receiving Palynziq Treatment for PKU (PALisade)

Phenylketonuria (PKU)

United States
Peking University

Not yet recruiting

3D Facial Scanning for Evaluating Autologous Fat Grafting in Craniofacial Deformities

Autografts | Adipocytes | Imaging, Three-Dimensional / Methods

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