Search clinical trials for: PK/PD

Total 59 results

Suzhou Suncadia Biopharmaceuticals Co., Ltd.

Not yet recruiting

PK/PD Study of SHR-2017 Injection in Patients With Bone Metastases

Patients With Bone Metastases

China
The Third Xiangya Hospital of Central South University

Not yet recruiting

PK/PD Study of Anti-Infective Drugs in Critically Ill Patients Receiving Extracorporeal Membrane Oxygenation Treatment (ECMO)

Critical Illness | Extracorporeal Membrane Oxygenation Complication

China
Wuhan Union Hospital, China
Yichang Humanwell Pharmaceutical Co., Ltd., China

Recruiting

PK/PD Properties and Safety of Remazolam Besylate for Injection in ICU Patients With Impaired Renal Function

Mechanically Ventilated Patients

China
Roswell Park Cancer Institute
National Institute on Drug Abuse (NIDA)

Not yet recruiting

PK/PD of Vaping THC-containing Liquids vs. Smoked Cannabis

Cigarette Smoking-Related Carcinoma
University Hospital, Ghent
Imec; Research Foundation Flanders

Not yet recruiting

Validation of Betalactam ML Prediction Models - TDMAide (TDMAide)

Infections

Belgium
Yale University
National Institute on Drug Abuse (NIDA); VA Connecticut Healthcare System

Recruiting

PK/PD of Oral and Vaporized Delta-9-Tetrahydrocannabinol (THC) in Older Adults

Pain, Tolerance | Oral vs Vaporized THC | Abuse Liability

United States
Hadassah Medical Organization

Recruiting

Adjustment of Aminoglycoside Dosing Based on Peak Serum Concentration and Bacterial Minimal Inhibitory Concentration

Aminoglycoside Dosing Based on PK/PD Characteristics

Israel
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

TCR-T Cell Therapy on Advanced Pancreatic Cancer

Pancreatic Cancer

China
Children's Hospital of Fudan University

Recruiting

PK/PD of Ceftazidime Avitbatan Sodium in Children With Severe Infection

Sepsis | Antibiotic Reaction

China
Children's Hospital of Fudan University

Not yet recruiting

PK/PD of Caspofungin in Children Severe Infection

Pharmacokinetics | Infection, Fungal

China
Novartis Pharmaceuticals

Completed

Study to Evaluate Treatment Compliance, Efficacy and Safety of an Improved Deferasirox Formulation (Granules) in Pediatric Patients (2-<18 Years Old) With Iron Overload

Transfusion-dependent Anemia

Egypt, Hungary, Turkey, United States, Bulgaria, Italy, Belgium, Russian Federation, Philippines, France, Malaysia, India, Oman, Panama, Lebanon, Thailand, Tunisia
Bio Sidus SA

Completed

PK/PD Study of 2 Agalsidase Formulations in Single Dose of 1 mg/kg Administered to Healthy Volunteers as IV Infusion

Fabry Disease

Argentina
University Hospital, Linkoeping
Linkoeping University

Suspended

Drug Exposure and Safety of a Shorter Tuberculosis Treatment Based on High-Dose Rifampicin and Pyrazinamide (HIGHSHORT-RP)

Tuberculosis, Pulmonary

Sweden
Jiangsu vcare pharmaceutical technology co., LTD

Completed

PK/PD Study of Vicagrel and Clopidogrel in Healthy Subjects With Different CYP2C19 Metabolizers

Acute Coronary Syndrome

United States, China
Telavant, Inc.
Pfizer

Completed

Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Intravenous and Multiple Subcutaneous and Intravenous Doses of PF-06480605 in Healthy Subjects.

Healthy

United States
AstraZeneca
PPD; Parexel; Covance; Iqvia Pty Ltd

Completed

PK/PD and Long Term Safety Study of Benralizumab in Children With Severe Eosinophilic Asthma (TATE)

Severe Uncontrolled Asthma

United States, Japan
Luye Pharma Group Ltd.

Completed

Pharmacokinetics, Pharmacodynamics and Safety of LY01005 in Patients With Prostate Cancer Compared to ZOLADEX®

Prostate Cancer

China
Vigonvita Life Sciences
Shanghai Institute of Materia Medica, Chinese Academy of Sciences

Completed

Acute Haemodynamic Study of TPN171H in Patients With Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension

China
Vastra Gotaland Region

Active, not recruiting

PK/PD Investigation of Calciumfolinat in Blood, Tumor and Adjacent Mucosa in Patient With Colon Cancer

Chemotherapy | Colon Cancer

Sweden
University of Southern California

Terminated

PK/PD of Vitamin D3 in Adults With CF

Vitamin D Deficiency | Cystic Fibrosis

United States
Shire

Completed

CINRYZE for the Treatment of Hereditary Angioedema Attacks in Children Under the Age of 12

Hereditary Angioedema (HAE)

United States, Germany, Hungary
Pontificia Universidad Catolica de Chile

Unknown

PK/PD Levobupivacaine With and Without Epinephrine After Ultrasound Guided ESP Block

Surgery | Nerve Block | Anesthetic Toxicity | Anesthetics Complications | Bupivacaine Overdose

Chile
Helsinn Healthcare SA

Completed

PK/PD Study of Netupitant and Palonosetron in Pediatric Patients for Prevention of Chemotherapy-induced Nausea and Vomiting (CINV)

Chemotherapy-induced Nausea and Vomiting (CINV)

United States, Russian Federation, Serbia, Ukraine
Isofol Medical AB

Completed

PK/PD Investigation of Modufolin (Arfolitixorin) in Plasma, Tumor and Adjacent Mucosa Adjacent Mucosa in Patients With Colon Cancer

Colonic Neoplasms

Sweden
Prince of Songkla University

Unknown

PK/PD and Clinial Outcomes of Beta-lactams in ICU Patients

Critical Illness | Bacterial Infections

Thailand
Yale University
National Institute on Drug Abuse (NIDA)

Completed

PK/PD Comparison of Guanfacine ER and IR

Smoking

United States
University of Minnesota
Eli Lilly and Company

Completed

PK/PD Study of U-500 Regular Insulin

Insulin Resistance | Type 2 Diabetes | High Insulin Requirements

United States
Guangdong Provincial People's Hospital

Unknown

PK/PD of the Sedatives, Analgesics and Antibiotics in Patients Receiving ECMO

Drug Effect

China
Gan and Lee Pharmaceuticals, USA

Completed

PK/PD Biosimilarity Study of Gan & Lee Insulin Lispro Injection vs. EU and US Humalog® in Healthy Males

Diabetes Mellitus

Germany
Gan and Lee Pharmaceuticals, USA

Completed

PK/PD Study of Gan & Lee Insulin Aspart Injection vs. US & EU NovoLog®/NovoRapid® in Healthy Males

Diabetes Mellitus, Type 1

Germany
Gan and Lee Pharmaceuticals, USA

Completed

PK/PD Biosimilarity Study of Gan & Lee Insulin Glargine Injection vs.US & EU Lantus® in Type 1 Diabetes Mellitus Patients

Diabetes Mellitus, Type 1

Germany
Massachusetts General Hospital
Food and Drug Administration (FDA); Center for Psychiatry And Behavioral Medicine...

Completed

PK/PD Pediatric ADHD Classroom Study

Attention Deficit Hyperactivity Disorder

United States
Jiangsu vcare pharmaceutical technology co., LTD

Completed

Pharmacokinetics and Pharmacodynamics of Vicagrel in Healthy Adult Subjects of Different CYP2C19

Healthy Subjects | PK/PD

China
Vance Fowler, M.D.
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

PK/PD and Safety/Tolerability of Two Dosing Regimens of Oral Fosfomycin Tromethamine in Healthy Adults (PROOF)

Healthy Subjects

United States
Faes Farma, S.A.
Allied Research International

Completed

PK/PD and Steady State Efficacy Study of Bilastine Compared With Placebo Given Orally in the Treatment of the Symptoms of SAR in an EEC Model (5-arm)

Seasonal Allergic Rhinitis | Hay Fever | Rhinoconjunctivitis

Canada
Loma Linda University

Completed

PK/PD of High Dose Pip/Tazo in Obese Patients

Obesity

United States
Centre Hospitalier Universitaire de Besancon

Unknown

PK/PD of Extended-infusion Meropenem, Piperacillin-tazobactam and Cefepime in the Early Phase of Septic Shock (PAACS)

Septic Shock

France
pH Pharma

Completed

PK/PD, Safety and Tolerability of PHP-201 Topical Eye Drop in Korean and Japanese Healthy Subjects

Healthy Volunteer

Korea, Republic of
Yooyoung Pharmaceutical Co., Ltd.

Completed

PK/PD Clinical Trial of YYD601 in Healthy Adult Male

GERD

Korea, Republic of
Xeris Pharmaceuticals
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Emissary...

Completed

PK/PD Study With G-Pump (Glucagon Infusion) in T1DM Patients

Hypoglycemia

United States
International Partnership for Microbicides, Inc.

Completed

PK/PD of Single Dose Dapivirine Vaginal Film

Pharmaokinetics
University Medical Center Groningen

Completed

PK/PD of Ertapenem In Patients With TB

PK of Ertapenem in TB Patients

Netherlands
Jiangsu HengRui Medicine Co., Ltd.

Unknown

Safety and Pharmacokinetics/Pharmacodynamics of SHR3824 in Type 2 Diabetes Patients With Renal Insufficient

Renal Insufficiency,Type 2 Diabetes

China
Gan and Lee Pharmaceuticals, USA

Completed

PK/PD Study of Gan & Lee's Insulin Glargine Injection in Comparison to Lantus in Type 1 Diabetes

Diabetes Mellitus, Type 1

United States
Radboud University Medical Center
Exponential Biotherapies Inc.

Completed

PK/PD of EA-230 During Endotoxemia

Endotoxemia | Systemic Inflammatory Response

Netherlands
Merckle GmbH

Completed

PK/PD of XM22 in Children With Ewing Family of Tumors or Rhabdomyosarcoma

Ewing Family of Tumors, Rhabdomyosarcoma

Bulgaria, Czech Republic, Hungary, Poland, Russian Federation, Ukraine
Boehringer Ingelheim

Completed

PK/PD, Long-term Safety and Efficacy of Tamsulosin Treatment in Children With Neurogenic Bladder

Bladder, Neurogenic

Belgium, Spain, United States, South Africa, Philippines, Italy, Korea, Republic of, Russian Federation, Germany, India, Brazil, Canada, Mexico, Ukraine
AZ Sint-Jan AV
Paul Tulkens, Louvain drug research institute, belgium; Francoise Van Bambeke... and other collaborators

Completed

Temocillin Pharmacokinetic in Hemodialysis

Gram-Negative Bacterial Infections | Renal Failure Chronic Requiring Hemodialysis

Belgium
Merck Sharp & Dohme LLC

Completed

PK/PD Study of Posaconazole for Empiric Treatment of Invasive Fungal Infections in Neutropenic Patients or Treatment of Refractory Invasive Fungal Infections (Study P01893)

Mycoses
Oslo University Hospital

Unknown

2012_PharmacoCRRT-study:Pharmacokinetics of Anti-infectives in Critically Ill Patients in Need of Continuous Renal Replacement Therapy (CRRT) (PharmacoCRRT)

Acute Kidney Injury | Acute Renal Failure | Critically Ill

Norway

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