Search clinical trials for: PNP

Total 64 results

Vienna Hospital Association

Recruiting

The Mamma HiToP Study

Chemotherapy-induced Peripheral Neuropathy

Austria
National Human Genome Research Institute (NHGRI)

Recruiting

A Natural History Study Seeks to Understand the Clinical, Genomic, Pharmacological, Laboratory, and Dietary Determinates of Pyrimidine and Purine Metabolism Disorders

Metabolic Disease | Purine-Pyrimidine Metabolism | AICDA, OMIM *605257, Immunodeficiency With Hyper-IgM, Type 2; HIGM2 | UNG, OMIM *191525, Hyper-IgM Syndrome 5 | NT5C3A<TAB>, OMIM *606224, Anemia, Hemolytic, Due to UMPH1 Deficiency | UMPS, OMIM *613891, Orotic Aciduria | DHODH, OMIM *126064,... and other conditions

United States
Merz Therapeutics GmbH

Recruiting

A Clinical Trial to Investigate Efficacy and Safety of NT 201 Injections Compared With Placebo Injections in Participants Aged 18 Years and Older With Chronic Nerve Pain After Shingles or Nerve Injury (PaiNT)

Moderate to Severe Chronic Peripheral Neuropathic Pain (PNP) Due to Postherpetic Neuralgia (PHN) or Peripheral Nerve Injury

Bulgaria, Germany, Poland, France, Hungary, Spain
Apurano Pharmaceuticals GmbH

Recruiting

Long Term Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Diabetic Polyneuropathy

Pain | Diabetes | Diabetic Neuropathies | Chronic Pain | Peripheral Neuropathy | Pain, Chronic | Chronic Pain Syndrome | Diabetic Polyneuropathy | Pain Syndrome | Peripheral Neuralgia | Peripheral Neuropathy With Type 2 Diabetis

Germany
Apurano Pharmaceuticals GmbH

Recruiting

Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Traumatic or Post-operative Peripheral Neuropathy

Pain | Chronic Pain | Neuropathic Pain | Peripheral Neuropathy | Pain, Chronic | Post Operative Pain | Chronic Pain Syndrome | Pain Syndrome | Peripheral Nerve Injury | Post-Traumatic Neuralgia | Peripheral Neuralgia | Plexopathy

Germany
Apurano Pharmaceuticals GmbH

Recruiting

Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Diabetic Polyneuropathy

Pain | Diabetes | Diabetic Neuropathies | Chronic Pain | Peripheral Neuropathy | Pain, Chronic | Chronic Pain Syndrome | Diabetic Polyneuropathy | Pain Syndrome | Peripheral Neuralgia | Peripheral Neuropathy With Type 2 Diabetis

Germany
Apurano Pharmaceuticals GmbH

Recruiting

Long Term Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Traumatic or Post-operative Peripheral Neuropathy

Pain | Chronic Pain | Neuropathic Pain | Peripheral Neuropathy | Pain, Chronic | Post Operative Pain | Chronic Pain Syndrome | Pain Syndrome | Peripheral Nerve Injury | Post-Traumatic Neuralgia | Peripheral Neuralgia | Plexopathy

Germany
Regeneron Pharmaceuticals

Not yet recruiting

A Trial to Learn if Receiving ALN-PNP siRNA is Safe and Well Tolerated, and How it Works in Adult Participants With Nonalcoholic Fatty Liver Disease (NAFLD) and a Genetic Risk Factor

Nonalcoholic Steatohepatitis (NASH) | Nonalcoholic Fatty Liver Disease (NAFLD) | Genetic Risk Factor
Regeneron Pharmaceuticals

Recruiting

A Trial to Learn if ALN-PNP is Safe and Well Tolerated in Healthy Adults and Adult Participants With Non-Alcoholic Fatty Liver Disease (NAFLD)

Healthy Volunteers | Non-alcoholic Fatty Liver Disease (NAFLD)

United States
Beijing Tsinghua Chang Gung Hospital

Recruiting

Neoadjuvant of Tislelizumab Combined With Chemotherapy Followed by Surgery in Unresectable Stage Ⅲ NSCLC

NSCLC, Stage III

China
Washington University School of Medicine
St. Jude Children's Research Hospital

Recruiting

Patients At Risk for Sensory Screening (HPARSS) to Enhance Sensory Deficit Screening in Childhood Cancer Survivors

Childhood Cancer

United States
Diskapi Teaching and Research Hospital

Recruiting

Transcutaneous Pulsed Radiofrequency in Diabetic Polyneuropathy

Neuropathy;Peripheral

Turkey
Universidad de Sonora
Universidad de León; Centro de Investigación en Alimentación y Desarrollo A.C. and other collaborators

Recruiting

Efficacy of a School-based Obesity Prevention Program in Mexican Schoolchildren: Cluster Randomized Controlled Trial

Pediatric Obesity

Mexico
University of Roma La Sapienza
Alexion Pharmaceuticals

Recruiting

Lysosomal Acid Lipase Activity in Nonalcoholic Fatty Liver Disease (NAFLD LAL)

Non-Alcoholic Fatty Liver Disease

Italy
Stanford University

Recruiting

Niclosamide in Pediatric Patients With Relapsed and Refractory AML

Acute Myeloid Leukemia (AML)

United States
Medicure

Recruiting

Oral Pyridoxal 5'-Phosphate for the Treatment of Patients With PNPO Deficiency (MEND-PNPO)

Pyridox(am)Ine 5'-Phosphate Oxidase Deficiency

United States, Australia
HealthCore-NERI
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Training in Exercise Activities and Motion for Growth (TEAM 4 Growth) RCT (T4G RCT)

Congenital Heart Disease

United States, Canada
Universitaire Ziekenhuizen KU Leuven
Byteflies

Recruiting

Advanced EEG Technology in Childhood Epilepsy (PnP)

Sleep Disorder | Epilepsy in Children

Belgium
National Institute of Allergy and Infectious Diseases...
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Pharmacokinetic Properties of Antiretroviral and Anti-Tuberculosis Drugs During Pregnancy and Postpartum

HIV Infections | Tuberculosis

United States, Malawi, Puerto Rico, South Africa, Thailand, Zimbabwe, Brazil, Kenya, Uganda, India, Tanzania, Botswana
University Hospital, Geneva
Meyer Jeremy. PhD. Co-investigator. University Hospital, Geneva.; Peloso Andrea... and other collaborators

Not yet recruiting

Prevena to Prevent Surgical Site Infection After Emergency Abdominal Laparotomy (CiPNT/SSI)

Surgical Site Infection | Hematoma | Seroma | Length of Stay
GeoVax, Inc.
Emory University; Stanford University; Thomas Jefferson University

Recruiting

Safety and Efficacy of Repeat Administration of Ad/PNP and Fludarabine Phosphate in Patients With Local Head/Neck Cancer

Recurrent Head and Neck Cancer

United States
Children's Hospital Medical Center, Cincinnati

Recruiting

National Collaborative to Improve Care of Children With Complex Congenital Heart Disease (NPC-QIC)

Hypoplastic Left Heart Syndrome (HLHS)

United States, United Kingdom, Canada
New York Medical College
Johns Hopkins University; Baylor College of Medicine; University of California... and other collaborators

Recruiting

Myeloablative Conditioning, Prophylactic Defibrotide and Haplo AlloSCT for Patients With Sickle Cell Disease (NYMC-571)

Sickle Cell Disease

United States
Duke University
Childhood Arthritis and Rheumatology Research Alliance

Recruiting

Observational Study of Pediatric Rheumatic Diseases: The CARRA Registry

Rheumatic Joint Disease

United States, Canada, Israel, Italy, Puerto Rico
University of Rochester

Recruiting

Clinical and Neuropsychological Investigations in Batten Disease

Batten Disease | Neuronal Ceroid Lipofuscinosis | Neuronal Ceroid Lipofuscinosis CLN6 | Neuronal Ceroid Lipofuscinosis CLN3 | Neuronal Ceroid Lipofuscinosis CLN5 | Neuronal Ceroid Lipofuscinosis CLN1 | Neuronal Ceroid Lipofuscinosis CLN2 | Neuronal Ceroid Lipofuscinosis CLN7 | Neuronal Ceroid Lipofuscinosis... and other conditions

United States
AstraZeneca
AstraZeneca K.K.

Active, not recruiting

A Study to Evaluate AZD2693 in Participants Who Are Carriers of the PNPLA3 148M Risk Allele With Non-cirrhotic Non-alcoholic Steatohepatitis With Fibrosis (FORTUNA)

Nonalcoholic Steatohepatitis

United States, Italy, Thailand, Germany, Korea, Republic of, Turkey, Vietnam, China, Malaysia, Taiwan, Hong Kong, Chile, Spain, Japan, Mexico, Brazil, Argentina, India, Singapore, Philippines, Peru, Colombia
Cambridge University Hospitals NHS Foundation Trust
University of Cambridge

Terminated

Molecular Investigation of Genetic Factors in CArDiovascular Diseases Using an BIOresource of Healthy Volunteers (CADBIO)

Cardiovascular Diseases

United Kingdom
AstraZeneca
Parexel

Completed

A Study to Assess Safety, Tolerability, PK and PD of AZD2693 in Non-alcoholic Steatohepatitis Patients

Non-alcoholic Steatohepatitis (NASH)

United States
Verona Pharma plc
Iqvia Pty Ltd

Completed

A Phase 3 Trial to Evaluate the Safety and Efficacy of Ensifentrine in Patients With COPD

Chronic Obstructive Pulmonary Disease

Denmark, United States, Bulgaria, Belgium, Poland, Spain, Canada, Estonia, Hungary, Slovakia
GB004, Inc.

Terminated

A Study With GB004 in Adult Subjects With Active Ulcerative Colitis (UC)

Ulcerative Colitis

United States, Korea, Republic of, Serbia, Ukraine, Romania, Georgia, Russian Federation, Moldova, Republic of, Poland
Central Hospital, Nancy, France

Completed

Pneumocystis Jirovecii Pneumonia in Non-HIV-infected Immunocompromised Patients (PnP-HIV-Free)

Pneumocystis Jirovecii Infection

France
Rahul Aggarwal
Novartis

Completed

LEE011 (Ribociclib) in Combination With Docetaxel Plus Prednisone in mCRPC

Prostate Cancer

United States
Rijnstate Hospital

Terminated

N-AcetylCysteine vs. Placebo to Prevent Neurotoxicity Induced by Platinum Containing Chemotherapy (NAC-PNP)

Carcinoma, Non-Small-Cell Lung | Mesothelioma | Carcinoma, Small Cell Lung

Netherlands
Columbia University

Active, not recruiting

Metformin for Ectopic Fat Deposition and Metabolic Markers in Polycystic Ovary Syndrome (PCOS)

Polycystic Ovary Syndrome | Metabolic Syndrome | Non-Alcoholic Fatty Liver Disease

United States
Hospital Universitario Central de Asturias

Completed

Study to Analyze the Surgical Site Infections in a Group of Patients Who Were Randomly Applied a Negative Pressure Therapy Dressing Versus Conventional Dressing

Surgical Wound Infection | Surgical Site Infection | Complication,Postoperative | Surgical Complication

Spain
Hoffmann-La Roche

Completed

A Study of Ocrelizumab in Participants With Relapsing Remitting Multiple Sclerosis (RRMS) Who Have Had a Suboptimal Response to an Adequate Course of Disease-Modifying Treatment (DMT)

Multiple Sclerosis, Relapsing-Remitting

Belgium, United Kingdom, Australia, Netherlands, Ireland, Norway, Turkey, Estonia, Denmark, Germany, Italy, Spain, Switzerland, France, Finland, Sweden, Czechia
University of Southern California
Children's Hospital Los Angeles

Completed

Healthy Eating Through Reduction Of Excess Sugar (HEROES)

NAFLD

United States
Esther Werth

Completed

The Role of the Circadian System in Neurological Sleep-wake Disorders (PNP)

Idiopathic Hypersomnia | Narcolepsy 1

Switzerland
LinkCare GmbH
Grünenthal GmbH; Schmerzpraxis Wiesbaden; Schmerz- und Palliativzentrum Rhein-Main...

Completed

Preferences in Pain Treatment: A Discrete Choice Experiment in Patients With Peripheral Neuropathic Pain (pNP) (DExPri)

Neuropathic Pain | Patient Preference | Neuralgia Peripheral

Germany
University of Campania "Luigi Vanvitelli"
Federico II University; University of Salerno

Completed

Effect of PNPLA3, TM6SF2 and MBOAT7 Genetic Variants on Non-alcoholic Fatty Liver Disease Therapeutic Outcome.

Insulin Resistance | Non-Alcoholic Fatty Liver Disease

Italy
BlueWind Medical

Completed

BlueWind Medical Reprieve System for the Treatment of PNP (PNP)

Peripheral Neuropathy

Belgium, Poland
Astellas Pharma Inc

Completed

Method of Pre-treatment for Application of QUTENZA Capsaicin 8% Patch (LIFT)

or Peripheral Nerve Injury (PNI) | Peripheral Neuropathic Pain (PNP) Due to Postherpetic Neuralgia (PHN)

Belgium, Czechia, Denmark, Ireland, Norway, Slovakia, United Kingdom
Astellas Pharma Europe Ltd.

Completed

A Study to Compare QUTENZA With Pregabalin for the Treatment of Peripheral Neuropathic Pain (PNP) After 8 Weeks of Treatment (ELEVATE)

Non-diabetic Painful Peripheral Polyneuropathy | Postherpetic Neuralgia (PHN) | Peripheral Nerve Injury (PNI)

Armenia, Austria, Belarus, Belgium, Bulgaria, Czechia, Finland, France, Germany, Greece, Hungary, Italy, Poland, Portugal, Romania, Russian Federation, Slovakia, Slovenia, Spain, Sweden, Turkey, United Kingdom
BlueWind Medical

Completed

BlueWind Reprieve System for the Treatment of PNP

Peripheral Neuropathic Pain

Israel
University of Leipzig
Universitätsklinikum Leipzig

Completed

Non-invasive Liver Screening for Risk Assessment for Coronary Heart Disease (NILS-R-CHD)

Coronary Disease | Non-alcoholic Fatty Liver Disease | Elasticity Imaging Techniques

Germany
Hoffmann-La Roche

Completed

A Study of Lebrikizumab in Participants With Uncontrolled Asthma on Inhaled Corticosteroids and a Second Controller Medication

Asthma

United States, Spain, Czechia, Belgium, Japan, Israel, Korea, Republic of, Italy, Peru, Serbia, France, Hungary, Bulgaria, Russian Federation, Ukraine, United Kingdom, Poland, Argentina, Canada, South Africa, New Zealand, Romania, G... and more
Hoffmann-La Roche

Completed

A Study of Lebrikizumab in Adolescent Participants With Uncontrolled Asthma Who Are on Inhaled Corticosteroids and a Second Controller Medication

Asthma

United States, United Kingdom, Hungary, Korea, Republic of, Spain, Brazil, Taiwan, Israel, Peru, France, Italy, South Africa, Germany, Poland, Colombia, Argentina, Mexico, Czechia, Ukraine, Slovakia, Canada, Japan, Portugal
Samyang Biopharmaceuticals Corporation

Completed

A Trial to Determine the Maximum Tolerated Dose and Evaluate the Safety and Pharmacokinetics of Docetaxel-PNP, Polymeric Nanoparticle Formulation of Docetaxel, in Subjects With Advanced Solid Malignancies

Advanced Solid Malignancies

Korea, Republic of
Samyang Biopharmaceuticals Corporation

Completed

Pharmacokinetic Study of Docetaxel-PNP and Taxotere to Treat Patient With Advanced Solid Cancer (DOPNP201)

Solid Tumor
Mansoura University

Completed

Purge Vs no Purge in Living Donor Liver Transplantation Recipients (PNP)

Ischemia Reperfusion Injury

Egypt

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