Preferences in Pain Treatment: A Discrete Choice Experiment in Patients With Peripheral Neuropathic Pain (pNP) (DExPri)

February 17, 2021 updated by: LinkCare GmbH
The objective of this study is to identify and weight attributes of topic and systemic pain treatment options relevant from the patients' perspective with peripheral neuropathic pain. The study will use a discrete choice experimental design to reach its objective.

Study Overview

Study Type

Observational

Enrollment (Actual)

153

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

    • Baden-Württemberg
      • Stuttgart, Baden-Württemberg, Germany, 70469
        • LinkCare GmbH
    • Hesse
      • Wiesbaden, Hesse, Germany, 65189
        • Schmerz- und Palliativzentrum Rhein-Main
      • Wiesbaden, Hesse, Germany, 65193
        • Schmerzpraxis Wiesbaden

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years and older (ADULT, OLDER_ADULT)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Sampling Method

Non-Probability Sample

Study Population

A total of 150 patients will be included in this study. Participating centers are outpatient centers, specialist in pain treatment in the state of Hesse.

Description

Inclusion Criteria:

  • Patients with diagnosed peripheral neuropathic pain (pNP) as assessed by study sites

Exclusion Criteria:

  • Patients with no sufficient knowledge in written or oral German as assessed by study sites

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
Stated-Preferences Observational Group
A discrete choice experiment will be conducted with participants with peripheral neuropathic pain in the stated-preferences observational group. The instrument will measure patient preferences for topical versus systemic pain treatment.
An online-based Discrete-Choice Experiment (DCE) using a survey for stated treatment preferences and socio-demographics. Furthermore, the neuropathic pain component will be assessed in all patients with the Numeric Pain Rating Scale instrument.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Patient preferences for topical and systemic pain treatment attributes
Time Frame: 20 minutes after survey start
Utility values obtained via multinominal logit estimates from discrete choice experiment
20 minutes after survey start

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Relevance of attributes attributed with topical and systemic pain treatment
Time Frame: 5 minutes after survey start
Derived from Likert scale
5 minutes after survey start
Marginal rate of substitution against pain reduction
Time Frame: 20 minutes after survey start
Derived from discrete choice experiment
20 minutes after survey start

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Investigators

  • Study Chair: Tino Schubert, MSc, LinkCare GmbH

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (ACTUAL)

February 11, 2020

Primary Completion (ACTUAL)

July 30, 2020

Study Completion (ACTUAL)

August 31, 2020

Study Registration Dates

First Submitted

November 29, 2019

First Submitted That Met QC Criteria

November 29, 2019

First Posted (ACTUAL)

December 3, 2019

Study Record Updates

Last Update Posted (ACTUAL)

February 21, 2021

Last Update Submitted That Met QC Criteria

February 17, 2021

Last Verified

February 1, 2021

More Information

Terms related to this study

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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