Search clinical trials for: Potential Drug-Drug Interactions

Total 2992 results

Eisai Inc.

Completed

A 2-Part Study to Assess Potential Metabolism-Based Drug-Drug Interactions of E2006 When Coadministered With Itraconazole, Rifampin, Midazolam, or Bupropion

Healthy Subjects

United States
Pfizer

Completed

A Drug-Drug Interaction Study To Investigate The Potential For Multiple Doses Of Palbociclib (PD-0332991) To Alter The Pharmacokinetics Of Oral Midazolam In Adult Healthy Women of Non-Childbearing Potential.

Healthy

United States
AstraZeneca
Parexel

Recruiting

Drug-Drug Interaction and Safety of AZD4041 Study (Part 1) and Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of AZD4041 Study in Opioid Use Disorder (Part 2).

Opioid Use Disorder

United States
Alexion Pharmaceuticals, Inc.

Recruiting

A Study to Evaluate Potential Drug Interactions Between ALXN2080 and Itraconazole, Fluconazole & Carbamazepine in Healthy Adults

Healthy

United Kingdom
Tomsk National Research Medical Center of the Russian...

Recruiting

Telecommunication Technology-based Online Survey

COVID-19 | Risk Factors | Polypharmacy | Drug Interactions | Self Medication

Russian Federation
Lawson Health Research Institute

Recruiting

Implementation of Personalized Medicine for Optimal Drug Therapy in Cancer

Cancer Pain | Nausea With Vomiting Chemotherapy-Induced | Depression, Reactive

Canada
Turning Point Therapeutics, Inc.

Recruiting

A Phase 1 Study to Evaluate the Potential Drug Interactions Between Repotrectinib and Metformin, Digoxin, and Rosuvastatin in Patients With Advanced Solid Tumors

Advanced Solid Tumor | Metastatic Solid Tumor

United States
Celgene

Recruiting

A Study Evaluating Potential Disease-Mediated Drug-Drug Interaction in Adult Participants With Active Eosinophilic Esophagitis Receiving Cendakimab

Eosinophilic Esophagitis

United States
University of Chicago

Recruiting

Evaluating Personalized Therapeutics Clinic (PTC) on Drug-Drug Interactions and Drug-Gene Interactions

Cancer | Advanced Solid Tumor | Advanced Cancer | Behavior Disorders | Mental Health Issue

United States
University of Ioannina

Recruiting

Interactive E-health Database for the Identification of Potential Interactions Among Drugs Prescribed to CKD Patient

Renal Insufficiency, Chronic

Greece
Biogen

Active, not recruiting

A Study to Assess the Potential for Gastric-pH Dependent Drug-Drug Interactions of BIIB122 With a Proton Pump Inhibitor in Healthy Participants

Healthy Volunteer

United States
Alexion Pharmaceuticals, Inc.

Completed

A Study to Investigate the Potential Drug Interactions Between ALXN2080 and Rosuvastatin and Metformin in Healthy Adult Participants

Healthy

United Kingdom
CTI BioPharma
PPD

Completed

Drug-Drug Interaction Study of Pacritinib and CYP450,Transporter Substrates, and CYP450 3A4 in Healthy Male Subjects

Drug Interactions

United States
Bellus Health Inc. - a GSK company

Completed

Evaluation of the Potential Drug-drug Interactions Between Gemfibrozil or Dabigatran Etexilate and Camlipixant

Healthy

Canada
Melinta Therapeutics, Inc.

Completed

Drug-Drug Interaction Potential of Orbactiv (Oritavancin) Co-Administered With Warfarin in Healthy Subjects

Healthy

United States
Pop Test Oncology LLC
Baylor College of Medicine; Michael E. DeBakey VA Medical Center; Congressionally... and other collaborators

Completed

Effects of Ethanol on the Pharmacokinetics of PT-150 (Formerly ORG34517) (PT150 PK Study)

Potential Treatment for Alcohol Dependence-Alcohol Interaction

United States
National Institutes of Health Clinical Center (CC)

Completed

Impact of Steady State Cobicistat and Darunavir/Cobicistat on the Pharmacokinetics and Pharmacodynamics of Oral Anticoagulants (Rivaroxaban, Apixaban) in Health Volunteers

Healthy Volunteers

United States
Sumitomo Pharma America, Inc.

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Drug Interaction Potential of Napabucasin in Healthy Volunteers

Drug-drug Interactions

United States
National Institutes of Health Clinical Center (CC)

Completed

Impact of Weekly Administration of Rifapentine and Isoniazid on Steady State Pharmacokinetics of Tenofovir Alafenamide in Healthy Volunteers (YODA)

Healthy Volunteers

United States
National Institute of Allergy and Infectious Diseases...
ViiV Healthcare

Suspended

Drug-Drug Interactions Between Rifapentine and Dolutegravir in HIV/LTBI Co-Infected Individuals

HIV Infection | LTBI

United States, Haiti, Botswana, Brazil, Thailand, Zimbabwe, Malawi, Peru, South Africa
Damanhour University
Alexandria University

Completed

Potential Drug Interactions With Bisoprolol in Egyptian Patients With ACS

Acute Coronary Syndrome

Egypt
Italfarmaco

Completed

Perpetrator DDI Potential of Givinostat as Inhibitor and Inducer of CYP3A and P-gp Activity

Drug-Drug Interaction

Portugal
Wageningen University and Research

Completed

Degree of Digestibility of Barley Rice Proteins (Bar-pro)

Digestive System

Netherlands
Aurinia Pharmaceuticals Inc.

Completed

Drug-Drug Interaction Study to Investigate Effects of Voclosporin on Pharmacokinetics of Simvastatin (Statin-DDI)

Drug-drug Interaction

United States
Celgene

Completed

A Study to Evaluate Potential Cytochrome P450 and Transporter Protein Interactions With CC-99677

Healthy Volunteer

United Kingdom
Emalex Biosciences Inc.
Syneos Health; Nuventra

Terminated

Drug-Drug Interaction Study to Evaluate the Effects of Ecopipam on the Pharmacokinetics of Multiple Substrates

Drug-Interactions

United States
University of California, San Francisco
San Francisco AIDS Foundation; California HIV/AIDS Research Program

Completed

Study of Truvada for HIV Pre Exposure Prophylaxis Using Daily Directly Observed Therapy to Look at Potential Interactions Between Truvada and Hormone Therapy (I-BrEATHe)

HIV Prevention | Transgender Health

United States
Cambridge University Hospitals NHS Foundation Trust
AstraZeneca; University of Cambridge

Terminated

A Study of the Pharmacokinetic and Pharmacodynamic Responses in Healthy and Altered Human Cardiovascular Systems (PRIME)

Drug-Related Side Effects and Adverse Reactions | Cardiovascular System Disease

United Kingdom
GlaxoSmithKline

Completed

A Cross-over Study to Evaluate the Effect of Itraconazole and Rifampicin on the Pharmacokinetics (PK) of GSK525762 in Healthy Female Subjects of Non Child Bearing Potential

Neoplasms | Drug Interactions

United States
Zagazig University

Completed

Risk Factors for Potential Drug -Drug Interactions: Study in Surgical Intensive Care Unit -Zagazig University Hospitals.

Drug Interaction

Egypt
Galmed Pharmaceuticals Ltd
Hammersmith Medicines Research; Diamond Pharma Services Regulatory Affairs... and other collaborators

Completed

Study of Potential for Drug Interactions Mediated by CYP3A4 Inhibition With Aramchol in Healthy Volunteers

Healthy

United Kingdom
Muğla Sıtkı Koçman University

Unknown

Epidemiology of Polipharmacy and Potential Drug-Drug Interactions in Elderly Cardiac Outpatients (EPIC)

Polypharmacy | Drug-drug Interactions

Turkey
University Hospital, Basel, Switzerland

Completed

Pharmacokinetic Interactions of Metamizole (Dipyrone) in Healthy Subjects

Inhibition | Drug-Drug Interaction | Induction

Switzerland
Akebia Therapeutics

Completed

Drug-Drug Interaction Study of Vadadustat With Digoxin, Adefovir and Furosemide

Drug Interaction Potentiation

Canada
Akebia Therapeutics

Completed

Drug-Drug Interaction Study of Vadadustat With Cyclosporine, Probenecid and Rifampin

Drug Interaction Potentiation

Canada
Akebia Therapeutics

Completed

Drug-Drug Interaction Study of Vadadustat With Rosuvastatin, Sulfasalazine, Pravastatin, Atorvastatin and Simvastatin

Drug Interaction Potentiation

Canada
Qure Healthcare, LLC
Aegis Sciences Corporation

Completed

DDI Effectiveness and Clinical Awareness (DECART)

Drug-Drug Interactions

United States
National Cheng-Kung University Hospital
Merck Sharp & Dohme LLC

Completed

Drug-Drug Interactions of Grazoprevir/Elbasvir in Taiwan

Drug Interaction Potentiation

Taiwan
Eisai Inc.
Purdue Pharma LP

Completed

Study to Assess the Pharmacokinetic Drug-Drug Interactions of Lemborexant When Coadministered With an Oral Contraceptive, Famotidine, or Fluconazole in Healthy Subjects

Healthy Subjects

United States
Medical University of South Carolina
University of South Carolina

Completed

Controlling Blood Pressure in Treatment Resistant Hypertension: A Pilot Study (TRH)

Hypertension

United States
Idorsia Pharmaceuticals Ltd.

Completed

A Clinical Study to Investigate the Potential Interactions Between Food and ACT-541468 and Between ACT-541468 and Midazolam

Healthy Subjects

Germany
Stendhal Americas, S.A.
LG Chem; Universidad Nacional Autonoma de Mexico

Completed

An Assessment of Pharmacokinetic Gemigliptin and Metformin Interactions in Healthy Mexican Volunteers

Diabetes Mellitus, Type 2

Mexico
Santhera Pharmaceuticals

Completed

A Study to Assess the Potential for Pre-systemic Inhibition of CYP3A by Idebenone Using Midazolam as a Substrate

Drug-Drug Interaction

France
University Hospital, Clermont-Ferrand
Neuromed IRCCS; Centre de Recherche en Nutrition Humaine d'Auvergne; Mediterranean...

Unknown

Diet Interactions With Human Gut Microbiota. The Potential Role of Mediterranean Diet Adherence. DIAGRAM, a Pilot Study (DIAGRAM)

Human Gut Microbiota

France
Jules Desmeules

Completed

Evaluation of the Potential Pharmacokinetic Interactions Between Probe Drugs in the Geneva Phenotyping Cocktail

Drug Interaction

Switzerland
National Institute on Drug Abuse (NIDA)

Completed

Assessment of Potential Interactions Between Intravenous Cocaine and Atomoxetine - 1

Cocaine-Related Disorders

United States
University of Cincinnati
National Institute on Drug Abuse (NIDA)

Completed

Safety Assessment of Potential Interactions Between IV Methamphetamine and Osmotic-Release Methylphenidate (OROS-MPH)

Methamphetamine Dependence | Methamphetamine Abuse

United States, Canada
National Institute on Drug Abuse (NIDA)

Completed

Assessment of Potential Interactions Between Cocaine and RPR 102681 - 1

Cocaine-Related Disorders

United States
National Institute on Drug Abuse (NIDA)

Unknown

Assessment of Potential Interactions Between Cocaine and Tolcapone - 1

Cocaine-Related Disorders

United States
National Institute on Drug Abuse (NIDA)

Unknown

Assessment of Potential Interactions Between Methamphetamine and Selegiline - 1

Amphetamine-Related Disorders

United States

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