Search clinical trials for: Pyronaridine artesunate

Total 247 results

Centre de Recherche Médicale de Lambaréné
Institute of Tropical Medicine, University of Tuebingen

Not yet recruiting

A Crossover Bioavailability Clinical Trial of Parenteral Pyronaridine and Artesunate

Severe Malarial Treatment

Gabon
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Recruiting

Phase IIa Proof of Concept Study of M5717-Pyronaridine in Adults and Adolescents With Acute Uncomplicated Plasmodium Falciparum Malaria (CAPTURE 1)

Acute Malaria

Burkina Faso, Gabon, Mozambique, Uganda
University Hospital Tuebingen
Sanaria Inc.; University of Oxford

Not yet recruiting

Comparing Safety and Protective Efficacy of Vaccine Candidate PfSPZ-CVac and MVA ME-TRAP/ ChAd63 ME-TRAP in Adults

Malaria
Shin Poong Pharmaceutical Co. Ltd.

Recruiting

The Safety and Efficacy of Pyronaridine-artesunate (Pyramax® or Artecom®)in COVID-19 Patients (PROVIDENCE)

Covid19

Philippines
Armed Forces Research Institute of Medical Sciences...
National Center for Parasitology, Entomology, and Malaria Control (CNM); Naval...

Recruiting

Drug Combinations of Atovaquone-Proguanil (AP) With ACT (APACT)

Plasmodium Falciparum Malaria (Drug Resistant)

Cambodia
Liverpool School of Tropical Medicine
London School of Hygiene and Tropical Medicine; Bill and Melinda Gates Foundation and other collaborators

Completed

Malaria as a Risk Factor for COVID-19 in Western Kenya and Burkina Faso (MALCOV)

Covid-19 | Malaria

Burkina Faso, Kenya
Medicines for Malaria Venture
Shin Poong Pharmaceutical Co. Ltd.

Completed

Relative Bioavailability of Pyronaridine-artesunate in Tablet and Granule Formulations in Healthy Volunteers

Malaria

Korea, Republic of
Medicines for Malaria Venture
Shin Poong Pharmaceuticals

Completed

Drug Interaction Study of Pyronaridine-artesunate & Metoprolol, & Redosing Study of Pyronaridine-artesunate

Malaria

Switzerland
Shin Poong Pharmaceutical Co. Ltd.

Completed

The Efficacy and Safety of Pyramax in Mild to Moderate COVID-19 Patients (Phase3)

COVID-19

Korea, Republic of, Colombia, Argentina, Poland, Chile, United Kingdom
Shin Poong Pharmaceutical Co. Ltd.

Completed

Pilot Clinical Trial to Explore Efficacy and Safety of Pyramax in Mild to Moderate COVID-19 Patients

COVID-19

Korea, Republic of
Danish Headache Center

Completed

The Effect of Levcromakalim Infusion on the Cranial Arteries Over Several Hours Using a High Resolution MRA Technique in a Randomized, Double-blind Placebo-controlled Design in Healthy Volunteers.

Headache | Dilatation of Cranial Arteries; MMA, STA and MCA

Denmark
Medicines for Malaria Venture
Shin Poong Pharmaceuticals; Institute of Tropical Medicine, University of Tuebingen

Completed

Pyronaridine and Artesunate (3:1) in Children With Acute Uncomplicated Plasmodium Falciparum Malaria

Uncomplicated Plasmodium Falciparum Malaria

Gabon
University of Ibadan
Shin Poong Pharm Co Ltd 161 yoksam-ro, Gangnam-Gu Seoul 135-925, Korea; Institute...

Completed

Efficacy and Safety of Pyronaridine-Artesunate Versus Artemether-Lumefantrine

Plasmodium Falciparum Malaria | Uncomplicated Malaria | Malaria Fever

Nigeria
Medicines for Malaria Venture
Shin Poong Pharmaceuticals

Terminated

Safety and Efficacy of Pyronaridine Artesunate Vs Chloroquine in Children and Adult Patients With Acute Vivax Malaria

Malaria

Korea, Republic of
Medicines for Malaria Venture
Shin Poong Pharmaceuticals

Completed

Pyronaridine Artesunate 3:1 Granule Formulation vs. Coartem© Crushed Tablets in P. Falciparum Malaria Pediatric Patients

Malaria

Burkina Faso, Congo, The Democratic Republic of the, Kenya, Mali, Mozambique, Philippines, Côte D'Ivoire, Gabon
Medicines for Malaria Venture
Shin Poong Pharmaceuticals

Completed

Pyronaridine Artesunate (3:1) Versus Coartem® in P Falciparum Malaria Patients

Malaria

Congo, The Democratic Republic of the, Gambia, Ghana, Indonesia, Kenya, Mali, Mozambique, Philippines, Senegal
Medicines for Malaria Venture
Shin Poong Pharmaceuticals

Completed

Pyronaridine Artesunate (3:1) in Children and Adults With Acute Plasmodium Vivax Malaria

Malaria

Indonesia, Cambodia, India, Thailand
Medicines for Malaria Venture
Shin Poong Pharmaceutical Co. Ltd.

Completed

Phase II Dose-ranging Study of Pyronaridine/Artesunate in Adults Patients With Plasmodium Falciparum Malaria

Plasmodium Falciparum Malaria

Cambodia, Gambia, Indonesia, Senegal, Thailand, Uganda
Medicines for Malaria Venture
Shin Poong Pharmaceuticals

Completed

Pyronaridine - Artesunate (3:1) Versus Mefloquine Plus Artesunate in Plasmodium Falciparum Malaria Patients

Falciparum Malaria

Cambodia, India, Thailand, Burkina Faso, Côte D'Ivoire, Tanzania, Vietnam
Shin Poong Pharmaceutical Co. Ltd.
Medicines for Malaria Venture

Completed

COVID-19 Treatment in South Africa

COVID-19

South Africa
Shin Poong Pharmaceutical Co. Ltd.

Completed

The Efficacy and Safety of Pyramax in Mild to Moderate COVID-19 Patients

COVID-19

Korea, Republic of
Centre national de recherche et de formation sur...
Programme national de lutte contre le paludisme (PNLP), Burkina Faso; Unité... and other collaborators

Unknown

Evaluation of Three Artemisinin-based Combinations for the Treatment of Uncomplicated Malaria in Childreen in Burkina Faso (CHIMIO2) (CHIMIO2)

Malaria | Burkina Faso

Burkina Faso
Medicines for Malaria Venture
Shin Poong Pharmaceuticals

Completed

Bioequivalence of Pyronaridine Artesunate To-be-marketed Tablet to the Clinical Trial Reference Tablet (SP-C-009-07)

Malaria

Switzerland
Centre de Recherche Médicale de Lambaréné

Completed

Effect of Artemisinin-based Combination Therapies on Schistosomiasis on Malaria Co-infection (SACT)

Schistosomiasis Haematobia

Gabon
London School of Hygiene and Tropical Medicine
Radboud University Medical Center; Malaria Research and Training Center, Bamako...

Completed

Pyronaridine-artesunate With Low Dose Primaquine for Preventing P. Falciparum Transmission (NECTAR1)

Malaria,Falciparum

Netherlands, Mali
Shin Poong Pharmaceutical Co. Ltd.
Medicines for Malaria Venture

Unknown

Pyramax in Asymptomatic Carriers of P. Falciparum Monoinfections

Malaria,Falciparum

Gambia, Zambia
Shin Poong Pharmaceutical Co. Ltd.
Medicines for Malaria Venture

Completed

Cohort Event Monitoring Study of Pyramax®

Malaria,Falciparum

Cameroon, Congo, The Democratic Republic of the, Congo, Côte D'Ivoire, Gabon
University of Oxford
NCHADS - Ministry of Health of Cambodia

Completed

Efficacy and Safety of Pyronaridine-artesunate for the Treatment in Uncomplicated Falciparum Malaria

Malaria, Falciparum

Cambodia
Royal Tropical Institute

Completed

Pyronaridine-artesunate and Artemether-lumefantrine for the Treatment of Paediatric Malaria (PAAL)

Malaria

Kenya
University of Oxford

Completed

Pharmacokinetic Study of Primaquine and Pyronaridine-Artesunate in Healthy Subjects

Healthy

Thailand
Medicines for Malaria Venture
Shin Poong Pharmaceuticals

Completed

Pyronaridine/Artesunate -Ritonavir Drug Drug Interaction Study

Malaria

Switzerland
Merck Sharp & Dohme LLC

Recruiting

A Study to Evaluate Antimalarial Activity and Safety of MK-7602 in Healthy Adults (MK-7602-003)

Malaria

Australia
UNC Lineberger Comprehensive Cancer Center

Not yet recruiting

Pharmacokinetics of Intravaginal, Self-administered Artesunate Vaginal Pessaries Among Women in Kenya

Cervix Cancer | Cervix Intraepithelial Neoplasia Grade 3 | Cervix; Intraepithelial Neoplasia, Grade I | Cervix; Intraepithelial Neoplasia, Grade II

Kenya
Frantz Viral Therapeutics, LLC
Anal Dysplasia Clinic MidWest; Laser Surgery Care, LLC

Recruiting

Artesunate Ointment for the Treatment of Anal HSIL in HIV-negative Participants (ART-AIN IIB-2)

Anal High-grade Squamous Intraepithelial Lesion | Anal HSIL | Anal HPV Infection

United States
London School of Hygiene and Tropical Medicine

Not yet recruiting

Parasite Clearance and Protection From Infection (PCPI) in Zambia

Malaria

Zambia
UNC Lineberger Comprehensive Cancer Center
Gilead Sciences

Recruiting

Artesunate Pessaries (Vaginal Inserts) for Cervical Precancer in Kenya

Precancerous Conditions | Cervix Cancer | Cervical Precancer | Cervix Neoplasm

Kenya
Frantz Viral Therapeutics, LLC
The Cleveland Clinic

Recruiting

Phase II Study of Artesunate Ointment for the Treatment of Vulvar High Grade Squamous Intraepithelial Lesions (Vulvar HSIL, VIN2/3) (ART-VIN IIB)

Vulvar Diseases | HPV Infection | Vulvar HSIL | High Grade Intraepithelial Neoplasia | HPV Disease | Pre-Cancerous Dysplasia | Vin II | Vin III | VIN, Usual Type | VIN 2 of Usual Type | VIN 3 of Usual Type | VIN Grade 2 | VIN Grade 3

United States
Joseph C. Wu

Not yet recruiting

Open-Label Dose-Escalation Treatment Study of Patients With IPF (DIAMOND)

Idiopathic Pulmonary Fibrosis

United States
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Recruiting

Efficacy, Safety, and PK of M5717 in Combination With Pyronaridine as Chemoprevention in Adults and Adolescents With Asymptomatic Plasmodium Falciparum Infection (CAPTURE-2)

Malaria Infection

Kenya, Burkina Faso, Gambia, Zambia
University of Oxford

Not yet recruiting

A Study to Find Out if a Combination of 3 Medicines for the Treatment of Malaria Works as Well and is as Safe and Tolerable as Combinations of 2 Medicines (FD-TACT)

Uncomplicated Plasmodium Falciparum Malaria
Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co...

Recruiting

A Study of FZ-AD004 in Patients With Advanced Solid Tumors

Advanced and Metastatic Solid Tumor

China
Praxis Precision Medicines

Recruiting

A Clinical Trial of PRAX-562 in Subjects With Developmental and Epileptic Encephalopathies (DEE) (EMBOLD)

SCN2A Encephalopathy | SCN8A Encephalopathy

United States, Spain
Muhimbili University of Health and Allied Sciences
Uppsala University; The Swedish Research Council

Not yet recruiting

Triple Artemisinin-based Combination Therapy for Delaying Drug Resistance Development - a Randomized Clinical Trial (3ACT)

Uncomplicated Plasmodium Falciparum Malaria

Tanzania
National Institute of Allergy and Infectious Diseases...
University of Maryland, Baltimore; Makerere University

Recruiting

Pharmacokinetic Study of IV Artesunate to Treat Children With Severe Malaria

Plasmodium Falciparum Infection

Uganda
SWOG Cancer Research Network
National Cancer Institute (NCI); Genentech, Inc.

Recruiting

Testing Drug Treatments After CAR T-cell Therapy in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma

Diffuse Large B-Cell Lymphoma | Recurrent Diffuse Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Grade 3b Follicular Lymphoma | Transformed Follic Lymph to Diff Large B-Cell Lymphoma | Transformed Marg Zone Lymph to Diff...

United States
Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co...

Recruiting

A Study of FDA022-BB05 in Subjects With Advanced Solid Malignant Tumors

Advanced Solid Tumors

China
Armaceutica, Inc.
Ifakara Health Research and Development Centre; Uganda Cancer Institute; African... and other collaborators

Recruiting

Pyronaridine in Acute Lymphoblastic Leukemia (ALL) and Acute Myeloid Leukemia (AML)

Acute Myeloid Leukemia (AML) | Acute Lymphoblastic Leukemia (ALL)

Senegal
Amivas (US), LLC

Recruiting

Observational Study of the Safety of Intravenous Artesunate Treatment of Pregnant Women and Their Infants

Pregnancy | Malaria

United States
Nepal Health Research Council
World Health Organization

Recruiting

Add-on Study on WHO Solidarity Trial Plus for COVID-19 in Nepal

COVID-19

Nepal
Institut National de la Santé Et de la Recherche...
Imagine Institute

Recruiting

Evaluation of the Effect of Artesunate in Friedreich Ataxia (FA) (ARTEMIS)

Friedreich Ataxia

France

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