Search clinical trials for: Receptors, Tumor Necrosis Factor

Total 67029 results

Centre Hospitalier Universitaire de Saint Etienne
Direction Générale de l'Offre de Soins

Not yet recruiting

Therapeutic Drug Monitoring-baSed adalimuMab De-escalatiOn in nOn-infecTious cHronic Uveitis (SMOOTH)

Uveitis | Chronic Disease

France
Boston Immune Technologies and Therapeutics

Not yet recruiting

A Clinical Trial in Adults With Non-Hodgkin Lymphoma (NHL), With a Particular Emphasis on Cutaneous T Cell Lymphoma (CTCL), Testing the Safety and Activity of a Novel Drug to Inhibit a Protein Called Tumor Necrosis Factor Receptor 2 That Drives Both Lymphoma Growth and Escape of the Immune System

Peripheral T-cell Lymphoma | NHL | Cutaneous T Cell Lymphoma
Egymedicalpedia

Not yet recruiting

Evaluation of TWEAK in Plaque Psoriasis and Psoriatic Arthritis Patients

Plaque Psoriasis

Egypt
Biocad

Recruiting

Study of the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of BCD-180 in Patients With Axial Spondyloarthritis (LEVENTA)

Axial Spondyloarthritis

Russian Federation, Belarus
Zhongshan Ophthalmic Center, Sun Yat-sen University
The First Affiliated Hospital of Soochow University; Shandong Eye Hospital; The...

Not yet recruiting

Effect of Immunosuppressants With Adalimumab Biosimilars vs Corticosteroids on Noninfectious Uveitis

Uveitis

China
Jagiellonian University

Recruiting

Activity of Chronic Inflammation in PCOS

Polycystic Ovary Syndrome

Poland
Prof Curdin Conrad
Centre Hospitalier Universitaire Vaudois

Not yet recruiting

TYK2 Inhibition in Paradoxical Psoriasis (TYPP)

Psoriasis

Switzerland
Vastra Gotaland Region

Recruiting

Comparison Between Infliximab and Adalimumab on Patients With Ulcerative Colitis

Inflammatory Bowel Diseases | Ulcerative Colitis

Sweden
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Treatment FOr Corticosteroid Dependent UveitiS (FOCUS)

Non Infectious Uveitis
AbbVie

Recruiting

A Study to Assess Adverse Events and Change in Disease Activity From Intravenous (IV) and Subcutaneous (SC) Lutikizumab in Adult Participants With Active Ulcerative Colitis

Ulcerative Colitis

United States
Sunshine Guojian Pharmaceutical (Shanghai) Co.,...

Not yet recruiting

A Study to Evaluate 608 in Patients With Ankylosing Spondylitis (AS)

Ankylosing Spondylitis

China
OncoCareClinic 308 Ltd

Recruiting

The 1st Tumor CytokinoTherapy Database (TCTD-1)

Oncology

Russian Federation
Centre Hospitalier Universitaire de Saint Etienne
Takeda France

Not yet recruiting

Comparison of Vedolizumab Treatment to Adalimumab Dose Intensification in Crohn's Disease Patients With Loss of Response or Biomarker Activity to Adalimumab on First Line With Therapeutic Drug Concentration. (VEDIAN)

Crohn's Disease

France
Ain Shams University

Not yet recruiting

Topical Erythropoietin Hydrogel in Management of Oral Lichen Planus

Oral Lichen Planus
Massachusetts General Hospital

Not yet recruiting

Cognitive Dysfunction and Inflammation in Depression: Experimental Inhibition Via Infliximab

Inflammation | Depressive Disorder, Major
University Medical Center Groningen

Recruiting

Fluorescence Imaging of Adalimumab-680LT in Inflammatory Bowel Disease (GUIDE)

Crohn Disease | Ulcerative Colitis

Netherlands
Ottawa Hospital Research Institute

Not yet recruiting

Hyperbaric Oxygen Therapy for Perianal Fistulizing Crohn's Disease Not Responsive or Intolerant to Conventional Care: HYPNOTIC Pilot Study (HYPNOTIC)

Inflammatory Bowel Disease (IBD)
AbbVie

Recruiting

A Study to Assess Adverse Events, Change in Disease Activity, and How the Drug Moves Through the Body in Children With Juvenile Psoriatic Arthritis (jPsA) Receiving Subcutaneously Injected Risankizumab or Adalimumab

Juvenile Psoriatic Arthritis

United States, Spain
Asan Medical Center
Samsung Medical Center; Seoul National University Hospital; Kyungpook National... and other collaborators

Not yet recruiting

Efficacy and Safety of Formulation Switching Between SC Infliximab and IV Infliximab in Patients With CD (CHAMELEON)

Crohn's Disease

Korea, Republic of
NorthShore University HealthSystem
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

Effects of TNF Blockade on Human BPH/LUTS

Benign Prostatic Hyperplasia (BPH)

United States
Academisch Medisch Centrum - Universiteit van Amsterdam...
Celltrion

Recruiting

inDuctIon tREatment With subCuTaneous Infliximab for Crohn's Disease (DIRECTCD)

Bowel Disease | Inflammatory Disease | Disease Crohn

Netherlands
Asan Medical Center

Not yet recruiting

TDM-based Infliximab Treatment for Active Perianal Fistulizing Crohn's Disease

Crohn Disease | Therapeutic Drug Monitoring | Infliximab | Perianal Fistula Due to Crohn's Disease | Magnetic Resonance Novel Index for Fistula Imaging in Crohn's Disease Score
Takeda

Recruiting

A Study of Vedolizumab Intravenous (IV) and Adalimumab or Vedolizumab and Ustekinumab in Adults With Crohn's Disease

Crohn's Disease

United States
Tom Appleton
Western University; Canadian Research Group in Immuno-Oncology

Not yet recruiting

Early Adalimumab Induction for Immune Checkpoint Inhibitor Associated Inflammatory Arthritis

Inflammatory Arthritis | Immune-related Adverse Event
IRCCS Burlo Garofolo

Recruiting

Therapeutic Monitoring of Infliximab and Adalimumab

Inflammatory Bowel Diseases

Italy
Tufts Medical Center

Not yet recruiting

Application of N-of-1 Rheumatoid Arthritis

Arthritis, Rheumatoid

United States
Mabscale, LLC

Recruiting

Study Evaluation of the Efficacy, Safety and Immunogenicity of Adalimumab in Comparison With Humira®

Plaque Psoriasis

Russian Federation
Hospital del Río Hortega
Francisco Javier Garcia Alonso; Jesús Barrio

Recruiting

Influence of HLA-DQA1*05 Genotype in Adults With Anti-TNF Treatment With Proactive Therapeutic Drug Monitoring. (Proa-DQ)

Inflammatory Bowel Diseases | Drug Monitoring

Spain
University of Washington
Janssen Scientific Affairs, LLC

Recruiting

Golimumab and Apalutamide for the Treatment of Castration-Resistant Prostate Cancer, TRAMP Study

Castration-Resistant Prostate Carcinoma | Prostate Adenocarcinoma

United States
Odense University Hospital
Royal Marsden NHS Foundation Trust; Aalborg University Hospital

Recruiting

Efficacy and Safety of Infliximab for Immune Checkpoint Inhibitor Induced Colitis (iCaD)

Colitis

Denmark, United Kingdom
Federico II University
Crohn's and Colitis Foundation

Not yet recruiting

AppenDectomy Vs ANti TNF-a in Inducing Clinical and EnDoscopic Remission in Left-sided Ulcerative Colitis (ADVANCED-UC)

Ulcerative Colitis
Assistance Publique - Hôpitaux de Paris

Recruiting

Certolizumab in Recurrent Implantation Failure (RIF) (CERTIFY)

Recurrent Unexplained Implantation Failure

France
University of Calgary
Alimentiv Inc.

Recruiting

PATHFINDER: Evaluating the Optimal First-Line Treatment Strategy for Moderate-to-Severely Active Ileal-dominant Crohn's Disease

Crohn Disease

Canada
Lihua Duan

Not yet recruiting

Recombinant Human Tumor Necrosis Factor-α Receptor Ⅱ Fusion Protein in the Treatment of Acute Gout

Acute Gout

China
Xijing Hospital of Digestive Diseases

Not yet recruiting

Autologous Platelet-rich Plasma (PRP) and Thrombin Coagulum for the Topical Treatment of Rectal Mucosal Ulcers

Ulcerative Colitis Chronic Moderate | Ulcerative Colitis Chronic Severe | Rectal Ulcer

China
Jamp Pharma Corporation

Recruiting

The Evaluation of Injection Site Pain and Adherence in Patients Switching From a Low To High Concentration Adalimumab (AVT-02) Across Multiple Indications. (EASE PAIN)

Rheumatoid Arthritis | Plaque Psoriasis | Crohn Disease | Ulcerative Colitis | Hidradenitis Suppurativa | Psoriatic Arthritis | Ankylosing Spondylitis

Canada
Taizhou Mabtech Pharmaceutical Co.,Ltd

Recruiting

Post-marketing Registry Study of Infliximab for Injection in Chinese Pediatric Crohn's Disease Patients

Crohn Disease

China
Sohag University

Not yet recruiting

Effect of Adalimumab Therapy on Psoriasis Patient

Psoriasi

Egypt
Hoffmann-La Roche

Recruiting

A Study to Evaluate the Long-Term Safety of Astegolimab in Participants With Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease

United States, Belgium, Australia, Israel, Bulgaria, Spain, France, United Kingdom, Denmark, Argentina, Germany, New Zealand, South Africa, Korea, Republic of, Poland, Canada, Chile, Czechia, Mexico, Netherlands, Romania, Sweden
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

"Comparison of the Efficacy and Safety of Adalimumab to That of Tocilizumab in Severe Uveitis of Behçet's Disease" (UVB)

Behcet's Uveitis
Emory University
National Institute of Mental Health (NIMH)

Recruiting

Anti-Inflammatory Challenge in Schizophrenia

Schizophrenia

United States
Postgraduate Institute of Dental Sciences Rohtak

Recruiting

Association of Apical Periodontitis With Systemic Level of Inflammatory Markers : A Longitudinal Intervention Study

Diabetes Mellitus, Type 2 | Apical Periodontitis

India
AbbVie

Recruiting

Study to Assess Change in Disease Activity and Adverse Events of Oral Upadacitinib Compared to Subcutaneous Adalimumab in Adult Participants With Moderate to Severe Rheumatoid Arthritis (SELECT- SWITCH)

Rheumatoid Arthritis

United States, Japan, United Kingdom, Canada, Korea, Republic of, Puerto Rico, South Africa, Hungary, Bulgaria, Spain, Portugal, Chile, Croatia, France, Belgium, Germany, Greece, Romania, Brazil, Italy, Serbia, China, Colombia
Research Institute of Epidemiology, Microbiology...

Recruiting

Impact of A. Lumbricoides on Pulmonary Aspergillosis Development

Chronic Pulmonary Aspergillosis | COPD Exacerbation Acute | Ascaris Lumbricoides Infection

Uzbekistan
Connecticut Children's Medical Center
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Emory... and other collaborators

Recruiting

Clinical, Imaging, and Endoscopic Outcomes of Children Newly Diagnosed With Crohn's Disease (CAMEO)

Crohn Disease

United States, Canada
Second Affiliated Hospital, School of Medicine,...
Shanghai Weike Biopharmaceutical Co., Ltd.

Recruiting

Hyperthermic Intraperitoneal Treatment of rmhTNF for CRCPM: Phase II Clinical Trial

Colorectal Cancer | Peritoneal Metastases

China
Insel Gruppe AG, University Hospital Bern
Bristol-Myers Squibb

Recruiting

Combined Microbiota and Metabolic Signature in Ulcerative Colitis Predicts Anti-Inflammatory Therapy Success (COMMIT)

Ulcerative Colitis

Switzerland
Assiut University

Not yet recruiting

Cancer Ratio,Pleural Fluid Adenosine Deaminase,Lactate Dehydrogenase, interferonY, Tumor Necrosis Factor,and Interleukins{2,12,18}for Differentiation Between Malignant and Non Malignant Pleural Effusion

Pleural Effusion, Malignant
University of Pennsylvania
Janssen Scientific Affairs, LLC

Recruiting

Guselkumab vs Golimumab in PsA TNF Inadequate Responder Patients (EVOLUTION)

Psoriatic Arthritis

United States
Children's Hospital Medical Center, Cincinnati
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Janssen...

Recruiting

Precise Infliximab Exposure and Pharmacodynamic Control (REMODEL-CD)

Crohn Disease

United States

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