Search clinical trials for: Research Subjects

Total 94275 results

VA Office of Research and Development

Not yet recruiting

Ketamine-assisted Integrative Treatment for Veterans With Chronic Low Back Pain and Comorbid Depression

Depression | Chronic Low Back Pain

United States
Acepodia Biotech, Inc.

Not yet recruiting

ACE2016 in Adult Subjects With Locally Advanced or Metastatic Solid Tumors Expressing Epidermal Growth Factor Receptor (EGFR)

Metastatic Solid Tumor | Locally Advanced Solid Tumor

United States
Innovent Biologics (Suzhou) Co. Ltd.

Not yet recruiting

Study of IBI3005 in Subjects With Unresectable, Locally Advanced or Metastatic Solid Tumors

Solid Tumors

Australia
Neuraly, Inc.

Not yet recruiting

A Study to Evaluate DD01 in Overweight/Obese Subjects With MASLD/MASH

NAFLD | NASH

United States
Aldeyra Therapeutics, Inc.

Recruiting

A Clinical Trial to Assess the Efficacy and Safety of Subjects With Dry Eye Disease

Dry Eye Disease

Canada
Melt Pharmaceuticals
Catalent; Evolution Research Group; MedTrials Incorporated; Pharmalex

Recruiting

A Study to Evaluate Efficacy and Safety of MELT-300 for Procedural Sedation in Subjects Undergoing Cataract Extraction With Lens Replacement (CELR)

Cataract

United States
Post Graduate Institute of Medical Education and...

Not yet recruiting

A RCT to Compare the Effectiveness of Nebulized Anticholinergics for Cough Suppression During Flexible Bronchoscopy (NAFCOF)

Subjects Undergoing Flexible Bronchoscopy

India
Stealth BioTherapeutics Inc.

Recruiting

ReNEW:Phase 3 Study of Efficacy, Safety & Pharmacokinetics of Subcutaneous Injections of Elamipretide in Subjects With Dry Age-Related Macular Degeneration (Dry AMD) (ReNEW)

Age-Related Macular Degeneration

United States
NeuShen Therapeutics

Recruiting

First-into-human Study of NS-136 in Healthy Subjects

Healthy Subjects

Australia
Daiichi Sankyo
Merck Sharp & Dohme LLC

Recruiting

A Study To Evaluate The Efficacy And Safety Of Ifinatamab Deruxtecan (I-DXD) In Subjects With Recurrent Or Metastatic Solid Tumors

Recurrent or Metastatic Solid Tumors

United States
Nested Therapeutics, Inc

Recruiting

A Study to Investigate the Safety and Efficacy of NST-628 Oral Tablets in Subjects With Solid Tumors (NST-628)

Glioma | Melanoma | NSCLC | Oncology | Solid Tumor, Adult | MEK Mutation | RAF Gene Mutation | Ras (KRAS or NRAS) Gene Mutation | MAPK Pathway Gene Mutation

Australia
McGill University Health Centre/Research Institute...

Not yet recruiting

Effect of Artificial Sweetener (AFS) on Glucose Metabolism in Patients With Type 1 Diabetes (T1D) (AFS_T1D)

Healthy Subjects | Type 1 Diabetes (T1D)
Calico Life Sciences LLC
AbbVie

Recruiting

A Thorough QT Study of ABBV-CLS-7262 in Healthy Subjects

Healthy

United States
Transcend Therapeutics

Recruiting

A Single, Ascending Dose Evaluation of the Safety, Pharmacokinetics of Methylone in Healthy Subjects

Post Traumatic Stress Disorder

Australia
Boundless Bio

Recruiting

Study of the RNR Inhibitor BBI-825 in Subjects With Tumors With Resistance Gene Amplifications (STARMAP)

Solid Tumor

United States
Biocad

Recruiting

A Study of the Efficacy and Safety of Monotherapy With BCD-264 and Darzalex in Subjects With Relapsed and Refractory Multiple Myeloma (DARVIVA)

Multiple Myeloma

Russian Federation
Xi'an Xintong Pharmaceutical Research Co.,Ltd.

Recruiting

Safety, Tolerability Phase Ia Study of XT1061 in Single and Multiple Doses in Healthy Subjects (XT1061)

Chronic Hepatitis b

China
Innovent Biologics (Suzhou) Co. Ltd.

Not yet recruiting

A Study of IBI363 in Subjects With Advanced Solid Malignancies

Solid Tumors

United States
Innovaderm Research Inc.

Not yet recruiting

Efficacy, Safety, and Tolerability of Abrocitinib in Subjects With Moderate to Severe Chronic Hand Eczema Refractory to Corticosteroid Therapy

Chronic Hand Eczema

Canada
Arbutus Biopharma Corporation

Not yet recruiting

Long-Term Follow-up Study for Subjects With CHB Previously Treated With Imdusiran (AB729)

Long Term Follow-up

United States, Australia, Hong Kong, Taiwan, United Kingdom, Korea, Republic of, Moldova, Republic of
National Center for Advancing Translational Sciences...
Leidos Biomedical Research, Inc.; ICON Government and Public Health Solutions...

Not yet recruiting

GS-441524 for COVID-19 SAD, FE, and MAD Study in Healthy Subjects

COVID-19
Pacira Pharmaceuticals, Inc

Recruiting

ZILRETTA in Subjects With Glenohumeral Osteoarthritis

Glenohumeral Osteoarthritis

United States
Public Health Vaccines LLC
Biomedical Advanced Research and Development Authority

Recruiting

Study to Evaluate the Recombinant Vesicular Stomatitis Virus (rVSV)-Marburg Virus Vaccine Candidate (PHV01) in Healthy Adult Subjects (PHV01)

Marburg Virus Disease

United States
Amneal Pharmaceuticals, LLC
CBCC Global Inc.; Amneal EU, Limited

Not yet recruiting

A Randomized, Double-blind, Parallel-group, Two-arm, Multiple Dose, Multicenter, Bioequivalence Study With Clinical Endpoint in the Treatment of Subjects With Chronic Open-angle Glaucoma or Ocular Hypertension in Both Eyes

Ocular Hypertension | Open-angle Glaucoma

United States
Intellia Therapeutics

Not yet recruiting

Long-Term Follow-Up (LTFU) of Subjects Treated With NTLA 2002

Hereditary Angioedema

France, New Zealand, United Kingdom
Innovaderm Research Inc.

Recruiting

Study to Evaluate the Efficacy of Ruxolitinib 1.5% Cream in Adult Subjects With Discoid Lupus Erythematosus

Discoid Lupus Erythematosus

Canada
University of Zurich
Swiss National Science Foundation; Swiss Paraplegic Research, Nottwil

Recruiting

Validity and Reliability of the 12-item Multiple Sclerosis Walking Scale (12-WS) in Subjects With Spinal Cord Injury (12-WS SCI)

Spinal Cord Injuries | Gait Disorders, Neurologic

Switzerland
Ethos Research & Development

Recruiting

Pilot Study: Impact of Biomarker-Guided Dietary Supplementation on Quality-of-Life Measures in Subjects With Chronic Pain

Chronic Pain

United States
Arbutus Biopharma Corporation

Recruiting

Study of Imdusiran (AB-729) in Combination With Intermittent Dosing of Durvalumab in Subjects With Chronic HBV Infection

Hepatitis B, Chronic

Georgia
Daiichi Sankyo

Recruiting

A Study of Valemetostat in Combination With DXd ADCs in Subjects With Solid Tumors

Advanced Solid Tumor

Japan, United States
Public Health Vaccines LLC
Coalition for Epidemic Preparedness Innovations

Recruiting

Study to Evaluate Safety and Immunogenicity of a Prime-Boost Regimen of rVSV-Nipah Virus Vaccine Candidate PHV02 in Healthy Adult Subjects

Nipah Virus Infection

United States
Neogene Therapeutics, Inc.

Recruiting

A Study of NT-112 in HLA-C*08:02-Positive Adult Subjects With Unresectable, Advanced, and/ or Metastatic Solid Tumors Positive for the KRAS G12D Mutation

Endometrial Cancer | Non-small Cell Lung Cancer | Pancreatic Ductal Adenocarcinoma | Colorectal Carcinoma | Solid Tumor, Adult | KRAS G12D

United States
Neurocentria, Inc.

Recruiting

Study to Evaluate NRCT-101SR in Pediatric Subjects With ADHD (ADHD)

Attention-Deficit/Hyperactivity Disorder (ADHD)

United States
Hercules
Prenuvo Inc

Recruiting

An Observational Study On TheAccuracy Of Whole-Body Magnetic Resonance Imaging (Wb-Mri) ScreeningTo Predict Clinically Significant Diagnoses In General Population Subjects Interested In Proactive And Advanced General Preventive Healthcare. (Hercules)

Cancer | Aneurysm | Neurologic Disorder | Metabolic Disease

United States
St. Mary's Research Center, Canada

Not yet recruiting

Tranexamic Acid Use on Pain, Mobility and Bleeding Following Total Hip and Total Knee Arthroplasty (TXA)

Postoperative Bleeding
Lithuanian University of Health Sciences

Recruiting

The Relations Among Endotoxin, Inflammatory Cytokines, Cognitive Markers and Brain MRI Changes in Subjects With Depressive Disorder

Inflammation | Cognitive Dysfunction | Genetic Predisposition to Disease | Endotoxemia | Major Depressive Disorder | Blood Brain Barrier Defect

Lithuania
Daiichi Sankyo
Merck Sharp & Dohme LLC

Not yet recruiting

A Study of Ifinatamab Deruxtecan Versus Treatment of Physician's Choice in Subjects With Relapsed Small Cell Lung Cancer (IDeate-Lung02)

Small Cell Lung Cancer

United States, Spain, Germany, Hungary, China, Italy, Korea, Republic of, United Kingdom, France, Belgium, Japan, Taiwan, Netherlands, Australia, Portugal, Poland, Turkey, Switzerland, Brazil, Canada, Romania
Jordan Collaborating Cardiology Group
The Jordan Cardiovascular Research Group JoCVRG; Yarmouk University School...

Recruiting

Cardiovascular Patients With no Standard Modifiable Risk Factors (SMuRF-less-ME1)

Cardiovascular Risk Factors

Jordan
Innovent Biologics (Suzhou) Co. Ltd.

Not yet recruiting

A Study of IBI3004 in Subjects With Unresectable, Locally Advanced or Metastatic Solid Tumors

Solid Tumor

Australia
AstraZeneca

Recruiting

EPIC-ATTR: A Study to Evaluate the Effect of Eplontersen on the Transthyretin Reduction and Long-term Safety in Chinese Subjects With Transthyretin Amyloid Cardiomyopathy (EPIC-ATTR)

Transthyretin Amyloid Cardiomyopathy

China
Biocad

Recruiting

A Trial of the Safety and Efficacy of Single-Dose Administration of ANB-010 in Subjects With Hemophilia A (EDELWEISS)

Hemophilia A

Russian Federation
Washington University School of Medicine
Paula C. & Rodger O. Riney Blood Cancer Research

Not yet recruiting

Safety and Efficacy of CS1 CAR-T (WS-CART-CS1) in Subjects With Multiple Myeloma

Multiple Myeloma

United States
China Medical University Hospital
China Medical University, China; Qualitix Clinical Research Co., Ltd.; Tian-I...

Not yet recruiting

Evaluate the Efficacy and Safety of "Formosa 1-Breath Free (NRICM101) " in Subjects With the Symptoms of COVID-19 or Influenza-like Disease

COVID-19 | Influenza Viral Infections

Taiwan
Chiesi Farmaceutici S.p.A.

Recruiting

A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of Inhaled CHF6333 After Single Doses in Healthy Volunteers and After Single and Repeated Doses in Subjects With Bronchiectasis

Bronchiectasis

United Kingdom
Seagen Inc.
RemeGen Co., Ltd.

Recruiting

A Study of Disitamab Vedotin Alone or With Other Anticancer Drugs in Solid Tumors

Stomach Neoplasms | Breast Neoplasms | Triple Negative Breast Neoplasms | Gastroesophageal Junction Adenocarcinoma | HER2 Positive Breast Neoplasms | HER2 Low Breast Neoplasms

United States
Mineralys Therapeutics Inc.

Recruiting

Efficacy and Safety of Lorundrostat in Subjects With Uncontrolled and Resistant Hypertension

Hypertension

United States, Italy, Germany, Australia, Canada, United Kingdom, Puerto Rico, Bulgaria, Spain
Mineralys Therapeutics Inc.

Recruiting

Efficacy and Safety of Lorundrostat Alone, and in Combination With Dapagliflozin in Subjects With Hypertension and Chronic Kidney Disease (CKD) With Albuminuria

Chronic Kidney Disease

United States
Cantargia AB

Recruiting

A Study to Investigate the Safety and Tolerability of CAN10 Antibody in Healthy Subjects and in Subjects With Plaque Psoriasis.

Healthy | Plaque Psoriasis

Germany
Arrowhead Pharmaceuticals

Recruiting

Study of ARO-DM1 in Subjects With Type 1 Myotonic Dystrophy

Myotonic Dystrophy 1

New Zealand, Australia
Danone Nutricia

Recruiting

An Exploratory Trial in Hong Kong to Explore the Effect of a New Formula

Healthy Subjects

Hong Kong, China

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