Search clinical trials for: Rheumatoid Arthritis, Inflammation

Total 11412 results

GlaxoSmithKline

Completed

Lipopolysaccharide (LPS) or Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) Challenge Study on Healthy Subjects

Arthritis, Rheumatoid

United Kingdom
Novartis Pharmaceuticals

Completed

ß-SPECIFIC 4 Patients: Study of Pediatric EffiCacy and Safety wIth FIrst-line Use of Canakinumab (ß-SPECIFIC 4)

Systemic Juvenile Idiopathic Arthritis (SJIA)

Italy, Russian Federation, Turkey, Belgium, Spain, Germany, France, Israel, Canada, United States, Hungary, Austria, Brazil, Sweden, Netherlands, Poland
AbbVie

Completed

A Phase 4 Trial Assessing the ImPact of Residual Inflammation Detected Via Imaging TEchniques, Drug Levels and Patient Characteristics on the Outcome of Dose TaperIng of Adalimumab in Clinical Remission Rheumatoid ArThritis (RA) Subjects (PREDICTRA)

Rheumatoid Arthritis | Musculoskeletal and Connective Tissue Diseases

United States, Australia, Austria, Canada, France, Germany, Greece, Hungary, Ireland, Italy, Netherlands, Spain, Sweden, United Kingdom
Vanderbilt University
Arthritis Foundation

Completed

Inflammation and the Heart

Rheumatoid Arthritis

United States
Sabine Dieperink
University of Copenhagen; University of Aarhus; Statens Serum Institut

Completed

Bloodstream Infections in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis | Staphylococcus Aureus Bacteremia
Göteborg University
Sahlgrenska University Hospital, Sweden

Completed

ADIRA (Anti-inflammatory Diet In Rheumatoid Arthritis) (ADIRA)

Rheumatoid Arthritis

Sweden
AbbVie

Withdrawn

Changes in Ultrasonographic Assessment of Inflammation Upon Initiation of Adalimumab Combination Therapy in Chinese Rheumatoid Arthritis (RA) Patients With Inadequate Response to Methotrexate

Rheumatoid Arthritis (RA)

China
Centre Hospitalier Universitaire de Saint Etienne
Pfizer

Completed

Impact of the Persistence of Inflammation at Doppler Ultrasound Level on the Structural Evolution of Erosion in Rheumatoid Arthritis Treated With Biotherapy

Rheumatoid Arthritis

France
Novo Nordisk A/S

Terminated

A Trial of NNC0109-0012, an Anti-IL-20 Biologic, in Patients With Active Rheumatoid Arthritis Who Are Inadequate Responders to Anti-TNFa Biologics

Inflammation | Rheumatoid Arthritis

United States, Mexico, France, Italy, Spain, Argentina, Belgium, Brazil, Czechia, Germany, Hungary, Poland, United Kingdom
Novo Nordisk A/S

Terminated

A Trial of NNC0109-0012, an Anti-IL-20 Biologic, in Patients With Active Rheumatoid Arthritis Who Are Inadequate Responders to Methotrexate

Inflammation | Rheumatoid Arthritis

United States, Mexico, Russian Federation, France, Italy, Spain, Argentina, Belgium, Brazil, Czechia, Germany, Poland, Ukraine, Hungary
UCB Pharma

Terminated

A 12 Week Study to Assess Changes in Joint Inflammation Using Ultrasonography in Patients With Rheumatoid Arthritis (RA) (SWIFT)

Rheumatoid Arthritis

United States
University of Colorado, Denver
Rheumatology Research Foundation

Completed

Periodontal Inflammation and Immunity in Preclinical Rheumatoid Arthritis

Rheumatoid Arthritis | Periodontal Disease

United States
GlaxoSmithKline
Cambridge University Hospitals NHS Foundation Trust

Terminated

A Study to Assess Inflammation in Rheumatoid Arthritis Using Molecular Imaging Techniques

Arthritis, Rheumatoid

United Kingdom
Göteborg University
Sahlgrenska University Hospital, Sweden

Completed

Mussels, Inflammation and Rheumatoid Arthritis (MIRA) (MIRA)

Rheumatoid Arthritis

Sweden
Sanofi

Completed

Activity and Safety of Oral Administration of SSR150106XB for the Reduction of Inflammation in Patients With Active Rheumatoid Arthritis (ACCORD-RA)

Rheumatoid Arthritis

Romania, Russian Federation, Ukraine, Bulgaria, Slovakia, Croatia, Czechia
Novo Nordisk A/S

Completed

First Human Dose Trial of NNC0215-0384 in Subjects With Rheumatoid Arthritis

Inflammation | Rheumatoid Arthritis

Germany
Novo Nordisk A/S

Completed

Efficacy of NNC109-0012 in Subjects With Active Rheumatoid Arthritis

Inflammation | Rheumatoid Arthritis

United Kingdom, Italy, Poland, Portugal, Spain, Germany, Czech Republic, Romania
Novo Nordisk A/S

Completed

A Multiple Dose Trial of NNC 0151-0000-0000 in Subjects With Rheumatoid Arthritis

Inflammation | Rheumatoid Arthritis

United Kingdom, Romania, Poland, Denmark, Czech Republic, Hungary
Novo Nordisk A/S

Completed

Dose-escalation Trial of Anti-C5aR Antibody in Healthy Subjects

Inflammation | Healthy | Rheumatoid Arthritis | Systemic Lupus Erythematosus

Netherlands
Novo Nordisk A/S

Completed

Safety and Tolerability of Anti-IL-20 in Healthy Volunteers and Patients With Rheumatoid Arthritis

Inflammation | Healthy | Rheumatoid Arthritis

Netherlands
Novo Nordisk A/S

Completed

Safety and Tolerability of Anti-IL-20 in Subjects With Rheumatoid Arthritis

Inflammation | Rheumatoid Arthritis

Poland, Belgium
Novo Nordisk A/S

Completed

First-in-Man Trial of NNC114-0005 in Healthy Subjects and Subjects With Rheumatoid Arthritis

Inflammation | Healthy | Rheumatoid Arthritis

Germany
Novo Nordisk A/S

Completed

Safety and Tolerability of NNC0114-0006 at Increasing Dose Levels in Subjects With Rheumatoid Arthritis

Inflammation | Rheumatoid Arthritis

Russian Federation, Germany
Innovaderm Research Inc.

Terminated

Etanercept in Rheumatoid Arthritis and Vascular Inflammation

Rheumatoid Arthritis | Vascular Inflammation

Canada
Novo Nordisk A/S

Completed

A Randomised, Double-blind, Placebo-controlled, Parallel-group Trial to Assess Clinical Efficacy of NNC0114-0006 in Subjects With Active Rheumatoid Arthritis

Inflammation | Rheumatoid Arthritis

Spain, Hungary, Serbia, Bulgaria, Poland, Russian Federation, Latvia
Siobhan Graham
University of Bath

Completed

The Effects of a Six-week Exercise Programme Undertaken by Women With Rheumatoid Arthritis

Rheumatoid Arthritis | Physical Activity

United Kingdom
Janssen Research & Development, LLC

Completed

Efficacy of NNC0142-0002 in Subjects With Rheumatoid Arthritis (RA)

Inflammation | Rheumatoid Arthritis

Germany, Russian Federation, Ukraine
Janssen Research & Development, LLC

Completed

First-in-man Trial of NNC0142-0002 in Patients With Rheumatoid Arthritis

Inflammation | Rheumatoid Arthritis

Germany
Amgen

Completed

Evaluating the Effect of Anakinra (r-metHuIL-1ra) on Vaccine AntibodyResponse in Subjects With Rheumatoid Arthritis (RA)

Rheumatoid Arthritis
Universidade Federal do Rio de Janeiro

Unknown

99mTc-anti-TNF-alpha Scintigraphy in the Evaluation of Inflammatory Processes Activity

Arthritis | Psoriatic Arthritis

Brazil
AIDS Clinical Trials Group
National Institute of Allergy and Infectious Diseases (NIAID)

Withdrawn

Effect of HAART Vs. Statin Treatment on Endothelial Function and Inflammation/Coagulation

HIV-1 Infection

United States
Nantes University Hospital

Terminated

Consequences of Anti-interleukin 6 Immunotherapy Treatment for Rheumatoid Arthritis on Periodontium (ParoPAR)

Rheumatoid Arthritis | Periodontitis

France
Bristol-Myers Squibb

Completed

PoC in Rheumatoid Arthritis With Methotrexate

Rheumatoid Arthritis, NOS

Taiwan, France, United States, Spain, Argentina, Mexico, Czech Republic, Korea, Republic of
Assistance Publique Hopitaux De Marseille

Completed

Does Etanercept Influence Tweak Modulation of Inflammation During Inflammatory Rheumatisms (Psoriatic Arthritis and Rheumatoid Arthritis)?

Rheumatoid Arthritis | Psoriatic Arthritis | Inflammatory Rheumatism

France
University of California, San Francisco
Genentech, Inc.

Completed

Cardiovascular Risk Markers in Patients With Rheumatoid Arthritis: Effect of Rituximab Therapy

Inflammation | Rheumatoid Arthritis | Endothelial Function

United States
Northern Orthopaedic Division, Denmark
Novo Nordisk A/S

Terminated

Examination of Biopsies From Healthy Knee Joints

Abnormality in Synovial Tissue

Denmark
Diakonhjemmet Hospital

Completed

Effects of Rosuvastatin on Carotid Artery Plaques in Patients With Inflammatory Joint Disease (RORAAS)

Rheumatoid Arthritis | Carotid Artery Plaque | Ankylosing Spondylitis

Norway
University of Rochester

Terminated

Draining PLN and Synovial Inflammation in RA Knee Joints Pre and Post Anti-TNF or B Cell Depletion Therapy

Rheumatoid Arthritis

United States
Taichung Veterans General Hospital

Completed

Assessment of Wrist Joint and Knee Joint Inflammation in Patients With Rheumatoid Arthritis by Quantitative Three Dimensional Power Doppler Ultrasonography (3D sono in RA)

Rheumatoid Arthritis
Innate Pharma

Completed

Safety and Tolerability of NNC0141-0000-0100 in Subjects With Rheumatoid Arthritis

Inflammation | Rheumatoid Arthritis

Germany
University of Athens

Completed

Effects of Interleukin-1 Inhibition on Vascular and Left Ventricular Function in Rheumatoid Arthritis Patients With Coronary Artery Disease

Coronary Artery Disease | Inflammation | Rheumatoid Arthritis

Greece
Vanderbilt University
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Completed

Inflammation and Insulin Resistance in Rheumatoid Arthritis

Rheumatoid Arthritis

United States
Novo Nordisk A/S

Completed

A Trial to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of NNC0215-0384 Administered to Subjects With Moderate to Severe Rheumatoid Arthritis

Inflammation | Rheumatoid Arthritis

Germany, Russian Federation, Poland, Hungary
Novo Nordisk A/S

Withdrawn

A Trial Investigating the Mechanism of Action of NNC0109-0012 (Anti-IL-20 mAb) Through Synovial Biopsies in Subjects With Rheumatoid Arthritis and an Inadequate Response to Methotrexate

Inflammation | Rheumatoid Arthritis
Santen Pharmaceutical(China) Co.,LTD

Completed

A Randomized, Parallel-Group Comparison Study of Topical Corticosteroids in Dry Eye Patients With Sjögren Syndrome

Dry Eye Syndromes | Sjögren Syndrome

China
Zhejiang University
Sir Run Run Shaw Hospital

Unknown

Study Evaluating the Efficacy of Thick Shell Mussel Lipid Extract in Chinese Subjects With Rheumatoid Arthritis

Rheumatoid Arthritis

China
Vanderbilt University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Atherosclerosis in Rheumatoid Arthritis

Heart Diseases | Cardiovascular Diseases | Inflammation | Arthritis, Rheumatoid | Atherosclerosis
National Institute of Arthritis and Musculoskeletal...

Completed

Interleukin-1 Trap to Treat Autoinflammatory Diseases

Inflammation | Familial Mediterranean Fever | Still's Disease, Adult-Onset

United States
Bristol-Myers Squibb

Completed

Study of the Safety of MDX-1342 in Combination With Methotrexate in Patients With Rheumatoid Arthritis (MDX1342-01)

Rheumatoid Arthritis

United States, Hungary, Germany, Ukraine, United Kingdom
Hanyang University

Completed

N-3 PUFA and Rheumatoid Arthritis in Korea

Rheumatoid Arthritis

Korea, Republic of

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