Search clinical trials for: Sequential dose-setting and expansion treatment

Total 472008 results

AstraZeneca
Parexel

Active, not recruiting

AZD4573 in Novel Combinations With Anti-cancer Agents in Patients With Advanced Blood Cancer

Advanced Haematological Malignancies

Spain, United States, Canada, Korea, Republic of, Poland, Australia, France, United Kingdom, Ireland
Peking University First Hospital

Not yet recruiting

Evaluation of Efficacy and Safety of Combination Therapy of Henagliflozin Proline, Retagliptin and Metformin in New Diagnosed Type 2 Diabetes Patients

Type 2 Diabetes
National Cancer Center, Korea

Recruiting

The Clinical Effectiveness and Safety of Intravesical Mitomycin-C and Gemcitabine Sequential Therapy (IMGeS)

Bladder Cancer

Korea, Republic of
RemeGen Co., Ltd.

Not yet recruiting

To Evaluate the Efficacy and Safety of Disitamab Vedotin Combined With Toripalimab Sequential Chemotherapy as Neoadjuvant Treatment in Patients With HR-positive, HER2-low Breast Cancer

Breast Cancer

China
Biotech Pharmaceutical Co., Ltd.

Not yet recruiting

A Study of Nimotuzumab Plus Concurrent Chemoradiotherapy Sequential Maintenance Treatment for Cervical Carcinoma

Cervical Cancer
Ontario Shores Centre for Mental Health Sciences
Sunnybrook Health Sciences Centre

Recruiting

Accelerated Bilateral Sequential Theta Burst Stimulation in Older Adults With Treatment-resistant Depression (CogniTReaD)

Depressive Disorder, Treatment-Resistant

Canada
Beijing Tiantan Hospital

Not yet recruiting

Early Intensive Antihypertensive Treatment in High-Risk Population of intraCerebral Hemorrhage ExpanSion Predicted by Artificial Intelligence (ARCHES)

Cerebral Hemorrhage
Shanghai Zhongshan Hospital
CSPC Ouyi Pharmaceutical Co., Ltd.

Recruiting

Dose Escalation and Expansion Clinical Trial of Irinotecan Liposome Combined With Oxaliplatin and 5-FU/LV Plus Bevacizumab as First-line Treatment of Metastatic Colorectal Cancer

Metastatic Colorectal Cancer

China
Simcere Pharmaceutical Co., Ltd

Not yet recruiting

The Efficacy and Safety of Edaravone Dexborneol Sequential Therapy in the Treatment of Patients With AIS

Subjects With Acute Ischemic Stroke
Stanford University
National Institute of Neurological Disorders and Stroke (NINDS)

Recruiting

Sequential, Multiple Assignment, Double Randomized Preference, Migraine Behavioral Trial (SMARTMig)

Migraine | Headache | Headache Disorders | Chronic Migraine

United States
Tanta University

Recruiting

Impact of Anterior Cross Bite Treatment on Children's Speech Performance

Quality of Life | Malocclusion | Cross Bite | Speech

Egypt
424 General Military Hospital

Recruiting

Sequential Therapies After Osteoanabolic Treatment (START)

Osteoporosis, Postmenopausal

Greece, Germany, Italy
Fu Jen Catholic University Hospital

Recruiting

Fourteen-Day Vonoprazan-Based Dual Therapy With Amoxicillin as First-Line Helicobacter Pylori Treatment in Comparison With Extended Sequential Therapy

Helicobacter Pylori Infection

Taiwan
Qianfoshan Hospital

Recruiting

Adebelizumab Combined With Chemotherapy and Radiotherapy Treat ES-SCLC

Extensive Small Cell Lung Cancer

China
RenJi Hospital

Not yet recruiting

SALT for Treatment of Patients With Early ACLF

Acute-On-Chronic Liver Failure

China
Zhejiang University

Recruiting

A Dose Escalation and Dose Expansion Trial of WTX212A in the Treatment of Patients With Advanced Malignant Tumors

Unresectable or Metastatic Advanced Solid Tumors

China
The First Hospital of Jilin University
CSPC Ouyi Pharmaceutical Co., Ltd.

Not yet recruiting

The Efficacy and Safety of the RCMOP Sequential Therapy as a First-line Treatment for Patients With Intermediate-to-high Risk Diffuse Large B-cell Lymphoma Who Had Incomplete Remission.

Diffuse Large B-cell Lymphoma

China
The Fourth Affiliated Hospital of Zhejiang University...

Recruiting

A Dose Escalation and Dose Expansion Clinical Study of STI-7349 in Subjects With Advanced Solid Tumors

Advanced Solid Tumor

China
Sun Yat-sen University

Not yet recruiting

Pianzumab Combined With AVD Regimen in the Treatment of Newly-diagnosed Advanced Classic Hodgkin Lymphoma

Classic Hodgkin Lymphoma
University of Texas Southwestern Medical Center
Exelixis

Recruiting

Sequential Treatment of Cabozantinib or Cabozantinib With Nivolumab for Advanced Renal Cell Carcinoma (RCC)

Renal Cell Carcinoma | RCC

United States
Enrico De Toni

Recruiting

Sequential or Up-front Triple Treatment With Durvalumab, Tremelimumab and Bevacizumab for Non-resectable Hepatocellular Carcinoma (HCC) Patients (MONTBLANC)

Hepatocellular Carcinoma

Germany
University of Calgary

Not yet recruiting

Accelerated High-dose Sequential Bilateral Theta Burst Stimulation for Treatment Resistant Depression

Treatment Resistant Depression
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Not yet recruiting

TQB2450 Injection Combined With Chemotherapy Followed by Sequential Combination With Anlotinib Hydrochloride Capsule for First-line Treatment of Advanced Squamous Non-small Cell Lung Cancer.

Advanced Squamous Non-Small Cell Lung Carcinoma

China
Kineta Inc.
Merck Sharp & Dohme LLC

Recruiting

A Clinical Trial of KVA12123 Treatment Alone and in Combination With Pembrolizumab In Advanced Solid Tumors (VISTA-101)

Melanoma | Sarcoma | Kidney Cancer | Carcinoma | Cancer | Breast Cancer | Head and Neck Cancer | Gastric Cancer | Pancreatic Cancer | Esophageal Cancer | Ovarian Cancer | Lung Cancer | Solid Tumor | Prostate Cancer | Colo-rectal Cancer | Thyroid Cancer | Uterine Cancer

United States
Region Skane
Lund University

Not yet recruiting

Effects on Mortality and Clinical Course of a Patient's Choice Model for Opioid Maintenance Treatment for Opioid Dependence - Evaluation of a System Enabling a Large Expansion of Treatment Providers and Treatment Access

Opioid Dependence | Overdose

Sweden
Kyungpook National University Hospital
National Cancer Center, Korea

Recruiting

Preoperative Sequential Short-course Radiation Therapy and FOLFOX for Locally Advanced Rectal Cancer (SOLAR)

Rectal Cancer

Korea, Republic of
The First Affiliated Hospital of Xiamen University
Fujian Cancer Hospital; Huizhou Municipal Central Hospital; Chipscreen Biosciences... and other collaborators

Recruiting

VCA Regimen Followed by D-MAG Regimen on the Treatment of Elderly Patients With Newly Diagnosed Acute Myeloid Leukemia (AML)

Leukemia, Myeloid, Acute | AML Stage, Adult

China
Second Affiliated Hospital of Soochow University

Not yet recruiting

Vinorelbine Metronomic Chemotherapy Combined With Hypofractionated Radiotherapy, PD-1/PD-L1 Sequential GM-CSF and IL-2 for Treatment of Advanced Refractory Non-small Cell Lung Cancer and Breast Cancer(PRaG 6.0)

Carcinoma, Non-Small-Cell Lung | Carcinoma Breast

China
Institut Paoli-Calmettes

Not yet recruiting

Collection of Sequential Samples From Patients With Malignant Myeloid Hemopathy for the Study of Treatment Resistance

Hematologic Cancer
Ruijin Hospital
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Not yet recruiting

SCRT Sequential Penpulimab in Combination With CAPEOX in the Neoadjuvant Treatment of MSS Locally Advanced Rectal Cancer (N-PRC)

Rectal Cancer | Locally Advanced
Liaocheng People's Hospital

Recruiting

Susceptibility-Guided Sequential Therapy for Helicobacter Pylori Infection

Helicobacter Pylori Infection

China
University Hospital, Basel, Switzerland
Clinical Trial Unit, University Hospital Basel, Switzerland

Recruiting

Detection of an Endovascular Treatment Target in Patients With an Acute, Spontaneous Intracerebral Hemorrhage (HemEXPLO)

Intracerebral Hemorrhage | Nontraumatic Intracerebral Hemorrhage

Switzerland
Shanghai Pudong Hospital

Recruiting

Efficacy and Safety Evaluation of Percutaneous Ommaya Capsule Injection of Autologous Bi-dimensional Specific T Cells in the Treatment of Glioma and in Combination With Pemetrexed in the Treatment of Brain/Meningeal Metastases

Glioma | Brain Metastases

China
Weijian Guo

Not yet recruiting

Fruquintinib Sequential BEV+FOLFIRI vs. BEV+FOLFIRI Sequential Fruquintinib in Metastatic Colorectal Cancer

Metastatic Colorectal Cancer

China
Huazhong University of Science and Technology

Recruiting

SBRT Sequential CapeOX Regimen Combined With Bevacizumab and Sintilimab in First-line Treatment of mCRC

Metastatic Colorectal Cancer

China
University Hospital, Montpellier

Recruiting

Efficacy of a Sequential Treatment Strategy in Rheumatoid Arthritis (SEQUENS-RA)

Rheumatoid Arthritis

France, Monaco
Peking Union Medical College Hospital
Beijing Tiantan Hospital; Capital Medical University

Recruiting

Sequential Treatment With RO-MTX After Pomalidomide, Orelabrutinib, Rituximab (POR) in Newly-diagnosed PCNSL

Primary Central Nervous System Lymphoma

China
Gang Wu

Not yet recruiting

Efficacy and Safety of DEB-BACE With Sequential Arotinib and Tirelizumab in the Treatment of Advanced NSCLC

Carcinoma, Non-Small Cell Lung
Hill-Rom

Recruiting

Oscillation and Lung Expansion (OLE) for Treatment of Neuromuscular Disease Patients

Neuromuscular Diseases

United States
Gang Wu

Not yet recruiting

An Exploratory Study of Sequential Transarterial Chemoembolization With Lipiodol and Neoadjuvant Chemotherapy in the Treatment of Initial Unresectable Colorectal Cancer (CRC)

Colorectal Cancer
Shanghai 10th People's Hospital

Recruiting

Cryoablation With Vestibular Expansion for the Treatment of Paroxysmal/Short-course Persistent Atrial Fibrillation (AF-PACC-CRYO)

Atrial Fibrillation

China
Qianfoshan Hospital

Recruiting

Efficacy and Safety Study of Medical Thoracoscope Cryotherapy Combined Standard First-line Treatment of Advanced Non-small Cell Lung Cancer and Malignant Pleural Effusion

Non Small Cell Lung Cancer

China
Pfizer

Recruiting

A Study to Learn About the Study Medicine (Called PF-07220060 in Combination With PF-07104091) In Participants With Breast Cancer and Solid Tumors

Breast Cancer | Solid Tumors

China, United States, Mexico, Bulgaria, Spain, Brazil, Czechia, Argentina, South Africa
Sun Yat-sen University

Recruiting

TACE Combined With Lenvatinib Versus TACE Sequential Lenvatinib in the Treatment of Intermediate/Advanced Liver Cancer

Hepatocellular Carcinoma

China
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
CSPC Ouyi Pharmaceutical Co., Ltd.

Recruiting

Neoadjuvant Treatment Pegylated Liposomal Doxorubicin Plus Cyclophosphamide Sequential Docetaxel Plus Trastuzumab and Pertuzumab Versus Docetaxel Plus Carboplatin Combined With Trastuzumab and Pertuzumab in HER-2 Positive Breast Cancer

Breast Cancer

China
ahmed ashraf abdelreheem

Recruiting

Comparison of Piezoelectric Split-crest Technique Versus Expansion Using Hand Driven Ridge Expanders in Treatment of Maxillary Narrow Ridges

Edentulous Alveolar Ridge

Egypt
Second Affiliated Hospital of Soochow University

Not yet recruiting

ADC Combined With Hypofractionated Radiotherapy, PD-1/PD-L1 Sequential GM-CSF and IL-2 for Treatment of HER-2 Positive Advanced Solid Tumors(PRaG3.0)

Carcinoma | Solid Tumor

China
National Taiwan University Hospital

Recruiting

The Optimal Long Term Treatment Strategy of Anti-resorptive Medications---The Extension of Denosumab Sequential Therapy

Osteoporosis | Bone Mineral Density

Taiwan
National Taiwan University Hospital

Recruiting

The Optimal Sequential Therapy After Long Term Denosumab Treatment

Osteoporosis

Taiwan
Shanghai Yueyang Integrated Medicine Hospital
Shanghai Skin Disease and Venereal Disease Hospital

Not yet recruiting

Sequential Treatment of Psoriasis With Traditional Chinese and Western Medicine

Plaque Psoriasis

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