Search clinical trials for: Severe Mitral Regurgitation

Total 9419 results

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
First Affiliated Hospital, Sun Yat-Sen University; First Affiliated Hospital... and other collaborators

Recruiting

TEER for Severe DMR of Low to Intermediate Surgery Risk

Mitral Regurgitation

China
University of Manitoba

Recruiting

Post Spinal Hemodynamic Changes in Aortic Stenosis and Mitral Regurgitation by VIS Index and Echocardiography

Severe Aortic Valve Stenosis | Severe Mitral Valve Regurgitation

Canada
Peijia Medical Technology (Suzhou) Co., Ltd.

Recruiting

Safety and Efficacy of the GeminiOne Transcatheter Valve Edge-to-Edge Repair System in Patients With Moderate-severe or Severe Degenerative Mitral Regurgitation

Mitral Regurgitation | Degenerative Mitral Valve Disease

China
Peijia Medical Technology (Suzhou) Co., Ltd.
West China Hospital; Second Affiliated Hospital, School of Medicine, Zhejiang... and other collaborators

Recruiting

Safety and Efficacy of the HighLife Transcatherter Mitral Valve Replacement System in Patients With Moderate-severe or Severe Mitral Regurgitation in China

Mitral Regurgitation

China
Pan Xiangbin

Not yet recruiting

To Evaluate the Efficacy and Safety of the Transfemoral Mitral Valve Repair System in the Treatment of Patients With Moderately Severe and Severe Functional Mitral Regurgitation(FMR) Who Remained Clinically Symptomatic After Guideline-directed Medical Treatment

Mitral Valve Insufficiency

China
Medtronic Cardiovascular

Recruiting

Transcatheter Mitral Valve Replacement in Patients With Severe Symptomatic Mitral Regurgitation - APOLLO-EU Trial (APOLLO-EU)

Mitral Regurgitation

Spain, Denmark, France, United Kingdom, Germany, Netherlands, Switzerland
Insel Gruppe AG, University Hospital Bern
University Hospital, Basel, Switzerland; Cardiocentro Ticino; Triemli Hospital

Recruiting

Prediction of Reverse Remodeling and Outcome in Patients With Severe Secondary Mitral Valve Regurgitation Undergoing Transcatheter Edge-to-edge Mitral Valve Repair (PRE-MITRA)

Severe Mitral Regurgitation

Switzerland
Epygon

Recruiting

First-In-Human Clinical Study for Treatment of Severe Mitral Valve INsufficiency With Epygon™ TRanscatheter Mitral VAlve System

Mitral Valve Regurgitation

Spain, Austria, Italy, Serbia
Mayo Clinic

Recruiting

Watchman for Patients With Atrial Fibrillation Undergoing Transcatheter Mitral Valve Repair (WATCH-TMVR) (WATCH-TMVR)

Nonvalvular Atrial Fibrillation | Severe Degenerative Mitral Regurgitation

United States, Canada
Kaohsiung Veterans General Hospital.
E-DA Hospital

Recruiting

The Prognostic Impact of Using High-dose Hydralazine in Severe Systolic Heart Failure With Hemodynamically Significant Mitral Regurgitation

Mitral Regurgitation | Systolic Heart Failure Stage D (Disorder)

Taiwan
HighLife SAS
ICON plc

Recruiting

Expanded Study of the HighLife 28mm Trans-septal Trans-catheter Mitral Valve in Patients With Moderate-severe or Severe Mitral Regurgitation and at High Surgical Risk

Mitral Regurgitation

Belgium, France, Germany, Australia, United Kingdom, Poland
UMC Utrecht
Maastricht University Medical Center; Academisch Medisch Centrum - Universiteit... and other collaborators

Recruiting

Dutch-AMR: Early Mitral Valve Repair Versus Watchful Waiting in Asymptomatic Patients With Severe Mitral Regurgitation (Dutch-AMR)

Mitral Regurgitation

Netherlands
Centre Hospitalier Universitaire, Amiens

Recruiting

Early Mitral ValvE Repair Versus Watchful Waiting for Asymptomatic SEvere Degenerative Mitral Regurgitation (REVERSE-MR)

Degenerative Mitral Regurgitation (MR) Due to Leaflet Prolapse

France
Nantes University Hospital
Abbott; Ministère de la Santé

Recruiting

Multicentre Study of MITRACLIP® Transcatheter Mitral Valve Repair in Patients With Severe Primary Mitral Regurgitation Eligible for High-risk Surgery (MITRA-HR)

Mitral Regurgitation

France, Monaco
Medtronic Cardiovascular

Recruiting

Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation. (APOLLO)

Mitral Valve Regurgitation

United States, Canada, Denmark
Ospedale San Raffaele
Istituto Clinico Humanitas; Central Clinical Hospital of the Ministry of Internal...

Recruiting

Annuloplasty for Not-Severe TR in Patients Undergoing MV Repair Versus Mitral Repair Only (NOSTRUM) (NOSTRUM)

Mitral Regurgitation | Tricuspid Disease

Italy, Poland
French Cardiology Society

Recruiting

Management and Clinical Outcomes of Patients With Severe Mitral Valve Disease Not Suitable for Surgery (MITRAGISTER)

Mitral Valve Disease

France
Asan Medical Center

Active, not recruiting

Early Surgery Versus Conventional Treatment for Asymptomatic Severe Mitral Regurgitation

Mitral Regurgitation

Korea, Republic of
Centre Cardiologique du Nord
Campus Bio-Medico University; University of Genova; Henri Mondor University Hospital and other collaborators

Enrolling by invitation

Transcatheter Versus Standard Surgical Mitral Valve Operation for Secondary Mitral Regurgitation (TEERMISO)

Severe Mitral Valve Regurgitation (Disorder)

France
Edwards Lifesciences
ICON plc

Terminated

Observational Registry on the HARPOON Device (REPLICATE)

Severe Degenerative Mitral Regurgitation Due to Mid-segment Posterior Leaflet Prolapse

Germany, Spain, Switzerland
Ottawa Heart Institute Research Corporation

Active, not recruiting

Prospective Treatment Algorithm Guiding Repair of Severe Ischemic Mitral Regurgitation

Mitral Regurgitation

Canada
Edwards Lifesciences

Active, not recruiting

Edwards EVOQUE Eos MISCEND Study

Mitral Valve Regurgitation (Degenerative or Functional)

United States, Canada
Enlight Medical Technologies (Shanghai) Co., Ltd

Active, not recruiting

Clinical Study of NovoClasp for Treating Moderate to Severe and Severe Degenerative Mitral Regurgitation

Degenerative Mitral Valve Disease

China
Jenscare Scientific

Enrolling by invitation

The JensClip Transcatheter Valve Repair System for Treating Functional Mitral Regurgitation

Functional Mitral Regurgitation

China
Icahn School of Medicine at Mount Sinai
National Heart, Lung, and Blood Institute (NHLBI); Canadian Institutes of Health...

Active, not recruiting

Long Term Follow Up for CTSN Mitral Valve Repair Studies

Coronary Artery Disease | Mitral Valve Insufficiency

United States, Canada
Michele De Bonis

Completed

Is Mitral Annuloplasty an Effective Treatment for Severe Atrial Functional MR?

Mitral Regurgitation

Italy
Michele De Bonis

Completed

Fate of Moderate Secondary Mitral Regurgitation in Patients Undergoing Aortic Valve Surgery for Severe Aortic Regurgitation

Aortic Regurgitation | Functional Mitral Regurgitation

Italy
Michele De Bonis

Completed

Commissural Closure to Treat Severe Mitral Regurgitation: Standing the Test of Time.

Degenerative Mitral Valve Disease

Italy
University Hospital, Clermont-Ferrand

Completed

Use of Pre-operative Global Longitudinal Strain to Predict Post-operative Left Ventricular Dysfunction in Mitral Regurgitation Surgery (DysPO IM)

Severe Mitral Regurgitation | Preserved Ventricular Ejection Fraction

France
Hangzhou Valgen Medtech Co., Ltd

Enrolling by invitation

Feasibility Study of Dragonfly System for Severe Tricuspid Regurgitation

Tricuspid Regurgitation

China
Neovasc Inc.

Active, not recruiting

Early Feasibility Study of the Neovasc Tiara™ Mitral Valve System (TIARA-I)

Mitral Valve Regurgitation

United States, Canada, Belgium
St. Boniface Hospital

Completed

Pre-operative Rehabilitation for Reduction of Hospitalization After Coronary Bypass and Valvular Surgery. (PREHAB)

Patients Waiting for Elective Isolated Coronary Artery Bypass Grafting (CABG) | Patients Waiting for Aortic Valve Repair/Replacement for Moderate Aortic Stenosis or Severe Regurgitation | Patients Waiting for Mitral Valve Repair/Replacement for Moderate Stenosis or Severe Regurgitation and other conditions

Canada
University Hospital Regensburg

Completed

Cardiopulmonary Exercise Testing in Severe Mitral Regurgitation

Pulmonary Hypertension | Mitral Valve Regurgitation

Germany
Ospedale San Raffaele

Completed

Minimally Invasive or Conventional Edge-To-Edge Repair for Severe Mitral Regurgitation Due to Bileaflet Prolapse in Barlow's Disease: Does the Surgical Approach Have an Impact on the Long-term Results?

Barlow's Disease | Prolapse; Mitral
Hospices Civils de Lyon

Withdrawn

Effectiveness and Safety of Mitral Valve Repair With the NeoChord DS1000 Artificial Chordae Delivery System Versus Conventional Surgery in Patients With Severe Primary Mitral Regurgitation Due to Isolated Leaflet Prolapse (MITRACHORD)

Cardiovascular Diseases

France
Cardiovalve Ltd.

Withdrawn

Feasibility Study of Patients With Severe MR Treated With the Cardiovalve TMVR System

Mitral Regurgitation

Greece, Poland
Icahn School of Medicine at Mount Sinai
National Heart, Lung, and Blood Institute (NHLBI); Canadian Institutes of Health... and other collaborators

Completed

Comparing the Effectiveness of Repairing Versus Replacing the Heart's Mitral Valve in People With Severe Chronic Ischemic Mitral Regurgitation

Coronary Artery Disease | Mitral Valve Insufficiency

United States, Canada
Hospices Civils de Lyon

Unknown

Multicentre Study of Percutaneous Mitral Valve Repair MitraClip Device in Patients With Severe Secondary Mitral Regurgitation (MITRA-FR)

Cardiovascular Diseases

France
Ancora Heart, Inc.

Completed

Feasibility of the AccuCinch® System for Left Ventricular Reshaping of the Mitral Apparatus to Reduce Functional Mitral Regurgitation and Improve Left Ventricular Function (LVRECOVER)

Severe Functional Mitral Regurgitation and Heart Failure

Australia
Edwards Lifesciences

Withdrawn

CardiAQ-Edwards™ Transcatheter Mitral Valve Replacement (TMVR) Study (RELIEF)

Mitral Valve Regurgitation

Italy, Canada, Denmark, Switzerland, France, Germany, Netherlands
Odense University Hospital
University of Southern Denmark; Danish Heart Foundation

Unknown

Hemodynamic Stress Test in Severe Mitral Regurgitation (HEMI) (HEMI)

Mitral Valve Regurgitation

Denmark
University of Zurich
Edwards Lifesciences

Unknown

Predictors of Postoperative Left Ventricular Function in Patients Undergoing Mitral Valve Repair for Severe Degenerative Mitral Regurgitation

Severe Degenerative Mitral Regurgitation

Switzerland
Deutsches Herzzentrum Muenchen

Unknown

Abrogation of Mitral Regurgitation Using the MitraClip System in High-Risk Patients Unsuitable for Surgery (ISAR-CLIP)

Mitral Regurgitation

Germany
Kaohsiung Veterans General Hospital.
National Science Council, Taiwan

Completed

Left Atrial Distensibility to Predict Left Ventricular Filling Pressure and Prognosis in Patients With Severe Mitral Regurgitation

Heart Failure | Atrial Fibrillation | Mitral Valve Insufficiency

Taiwan
Xijing Hospital

Recruiting

Transcatheter Aortic Valve Replacement for Pure Severe Aortic Valve Regurgitation

Aortic Valve Regurgitation

China
Saint Petersburg State University, Russia

Not yet recruiting

Influence of Lung Ultrasonography on the Prognosis and Postoperative Outcomes in Cardiac Surgical Patients

Ischemic Heart Disease | Mitral Insufficiency | Aortic Stenosis, Severe | Mitral Stenosis | Aortic Insufficiency | Ascending Aortic Aneurysm | Mitral Stenosis With Insufficiency | Tricuspid Insufficiency

Russian Federation
Oxford University Hospitals NHS Trust
Edwards Lifesciences

Recruiting

Early Discharge After Mitral and Tricuspid Edge-to-edge Repair: an Assessment of Feasibility and Safety (EARLY-Edge)

Heart Failure | Mitral Regurgitation | Tricuspid Regurgitation | Mitral Repair

United Kingdom
Fundación para la Investigación Biosanitaria del...
Meditrial Europe Ltd.

Not yet recruiting

Early Transcatheter Mitral Valve Repair After Myocardial Infarction (EMCAMI)

Acute Mitral Regurgitation

Spain, Italy, Netherlands, Israel
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Development and Validation of the Prediction Model for Functional Mitral Regurgitation Regression in Heart Failure Patients Taking Guideline-directed Medical Therapy

Heart Failure | Mitral Regurgitation

China
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Multimodality Imaging Assessment of the Severity of Mitral Regurgitation

Mitral Regurgitation

China

Search clinical trials for: Severe Mitral Regurgitation

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