Search clinical trials for: Systemic Immunosuppressive Therapy

Total 69311 results

Kyverna Therapeutics

Not yet recruiting

A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Therapy, in Subjects With Systemic Sclerosis

Systemic Sclerosis | Systemic Sclerosis - Diffuse Cutaneous | Systemic Sclerosis - 2013 ACR/EULAR Classification Criteria
Second Affiliated Hospital, School of Medicine,...

Recruiting

A Prospective Study of Whole-Brain RT Combined With Thiotepa Sheath Injection Combined With Systemic Therapy for the Primary Disease in the Treatment of Meningeal Metastases in Solid Tumors

Solid Tumor Leptomeningeal Metastasis

China
Shen Lei

Not yet recruiting

Comparison of Nafamostat and Unfractionated Heparin in RRT for Sepsis Associated AKI

Sepsis

China
Kyverna Therapeutics

Recruiting

A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Therapy, in Subjects With Refractory Lupus Nephritis (KYSA-3)

Lupus Nephritis | Lupus Nephritis - WHO Class IV | Lupus Nephritis - WHO Class III

Germany
Guangdong Ruishun Biotech Co., Ltd
Changhai Hospital; Peking University People's Hospital; RenJi Hospital; The Affiliated...

Not yet recruiting

A Study of RJMty19 in Refractory Systemic Lupus Erythematosus (SLE)

Systemic Lupus Erythematosus

China
National Institute of Geriatrics, Rheumatology...
Medical Research Agency, Poland

Not yet recruiting

Study of the Efficacy of Nintedanib+Tocilizumab in Patients With Systemic Sclerosis and Interstitial Lung Disease (NINTOC-TU)

Systemic Sclerosis | Interstitial Lung Disease

Poland
Sana Biotechnology

Recruiting

Study Evaluating SC291 in Subjects With Severe r/r B-cell Mediated Autoimmune Diseases (GLEAM) (GLEAM)

Systemic Lupus Erythematosus | Microscopic Polyangiitis | Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis | Lupus Erythematosus | SLE (Systemic Lupus) | Granulomatous Polyangiitis

United States
Jiangsu Renocell Biotech Company
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical...

Recruiting

RY_SW01 Cell Injection Therapy in Active Lupus Nephritis

Lupus Nephritis

China
Wang Mo

Recruiting

Stratified Therapy on Pediatric AAGN (STPARS)

Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis | ANCA-Associated Glomerulonephritis

China
Chinese SLE Treatment And Research Group

Recruiting

Efficacy and Safety for Telitacicept in the Remission Maintenance Treatment of ANCA-associated Vasculitis (TTCAZAREM)

ANCA-associated Vasculitis | Maintenance Therapy

China
Peking Union Medical College Hospital
Beijing Tongren Hospital; Southern Medical University

Recruiting

Construction of Diagnosis and Treatment System for Primary Vitreoretinal Lymphoma

Primary Vitreoretinal Lymphoma

China
Kyverna Therapeutics

Recruiting

A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Therapy, in Subjects With Refractory Lupus Nephritis

Lupus Nephritis | Lupus Nephritis - World Health Organization (WHO) Class III | Lupus Nephritis - WHO Class IV

United States
Nanjing University School of Medicine

Recruiting

Trial of Belimumab Combined With Multi-target Induction Therapy in Lupus Nephritis (BEAM)

Lupus Nephritis | Safety Issues | Remission

China
Second Xiangya Hospital of Central South University
Peking Union Medical College Hospital; The Second Hospital of Hebei Medical... and other collaborators

Recruiting

MMF Versus CYC in the Induction Therapy of Pediatric Active Proliferative LN (MyCITS)

Lupus Nephritis | Mycophenolate Mofetil | Cyclophosphamide

China
National Cancer Institute (NCI)

Recruiting

The Lowest Effective Dose of Post-Transplantation Cyclophosphamide in Combination With Sirolimus and Mycophenolate Mofetil as Graft-Versus-Host Disease Prophylaxis After Reduced Intensity Conditioning and Peripheral Blood Stem Cell Transplantation

Hematopoietic Stem Cell Transplantation | Peripheral Blood Stem Cell Transplantation

United States
Sun Yat-sen University

Recruiting

Whole-target Consolidation Therapy Under Systemic Therapy for Oligometastatic Nasopharyngeal Carcinoma

Nasopharyngeal Carcinoma

China
National Cancer Institute (NCI)

Recruiting

M9241 in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer or Intrahepatic Cholangiocarcinoma

Colorectal Neoplasms | Colorectal Cancer | Cholangiocarcinoma | Bile Duct Cancer | Bile Duct Neoplasms | Metastatic Colorectal Cancer (Mcrc) | Intrahepatic Cholangiocarcinoma (Icc) | Intrahepatic Bile Duct Cancer

United States
Institutul Clinic Fundeni

Recruiting

Minimizing Glucocorticoid Administration in Patients With Proliferative Lupus Nephritis (GLUREDLUP)

Lupus Nephritis

Romania
National Institute of Oncology, Hungary

Not yet recruiting

Neoadjuvant Treatment of Breast Cancer

Breast Cancer

Hungary
Sun Yat-sen University

Recruiting

Corticosteroid Combining Noncorticosteroid Systemic Immunomodulatory Therapy in VKH

Vogt Koyanagi Harada Disease (VKH)

China
Hui-Chuan Sun

Recruiting

Hepatic Artery Infusion Chemotherapy for Unresectable Hepatocelluar Carcinoma Who Failed to Systemic Therapy

Hepatocellular Carcinoma

China
GlaxoSmithKline

Recruiting

Open-label Study of Belimumab Plus Standard Therapy in Chinese Pediatric Participants With Active Systemic Lupus Erythematosus (SLE)

Systemic Lupus Erythematosus

China
Assistance Publique - Hôpitaux de Paris
URC-CIC Paris Descartes Necker Cochin

Not yet recruiting

Study of Salvage Therapy to Treat Patients With Granulomatosis With Polyangiitis (SATELITE)

Granulomatosis With Polyangiitis | Anti-neutrophil Cytoplasmic Antibody-associated Vasculitis

France
University of California, Irvine

Recruiting

Study of Sequential Systemic Therapy + Intraperitoneal Paclitaxel in Gastric/GEJ Peritoneal Carcinomatosis (STOPGAP)

Gastric Cancer | Peritoneal Carcinomatosis | Gastroesophageal Junction Adenocarcinoma

United States
Chinese SLE Treatment And Research Group
The First Affiliated Hospital of Anhui Medical University; Shanghai Zhongshan... and other collaborators

Recruiting

Comparison of the Efficacy of Leflunomide and Azathioprine for the Maintenance Therapy of ANCA Associated Vasculitis (LEFAZAREM)

ANCA Associated Vasculitis | Maintenance Therapy

China
Alexion

Recruiting

Study of Ravulizumab in Proliferative Lupus Nephritis (LN) or Immunoglobulin A Nephropathy (IgAN) (SANCTUARY)

Lupus Nephritis | Immunoglobulin A Nephropathy

United States, Australia, Canada, France, Germany, Italy, Korea, Republic of, Netherlands, Poland, Singapore, Spain, Sweden, Taiwan, United Kingdom
National University Hospital, Singapore
GlaxoSmithKline

Recruiting

Sequential Belimumab and T-cell Based Therapy in SLE

Systemic Lupus Erythematosus

Singapore
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

TBI Using IMRT and Cyclophosphamide Prior to Stem Cell Transplant for the Treatment of Severe Systemic Sclerosis

Systemic Scleroderma

United States
Hospital for Special Surgery, New York
GlaxoSmithKline

Recruiting

Belimumab and Rituximab Combination Therapy for the Treatment of Diffuse Cutaneous Systemic Sclerosis

Systemic Sclerosis

United States
Centre Hospitalier Departemental Vendee

Recruiting

Maintaining or Stopping Immunosuppressive Therapy in Patients With ANCA Vasculitis and End-stage Renal Disease (MASTER-ANCA)

End Stage Renal Disease | Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis

France
Federation Francophone de Cancerologie Digestive

Recruiting

Systemic Oxaliplatin or Intra-arterial Chemotherapy Combined With LV5FU2 +/- Irinotecan and an Target Therapy in First Line Treatment of Metastatic Colorectal Cancer Restricted to the Liver (OSCAR)

Colorectal Neoplasms

France, Switzerland
Paul Szabolcs

Recruiting

Reduced Intensity Conditioning for Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT (HSCT+RIC)

Congenital Bone Marrow Failure Syndromes | Inflammatory Conditions | Primary Immunodeficiency (PID) | Inherited Metabolic Disorders (IMD) | Hereditary Anemias | Systemic Juvenile Idiopathic Arthritis (sJIA)

United States
Millennium Pharmaceuticals, Inc.

Terminated

Study of Dexamethasone Plus IXAZOMIB (MLN9708) or Physicians Choice of Treatment in Relapsed or Refractory Systemic Light Chain (AL) Amyloidosis

Relapsed or Refractory Systemic Light Chain Amyloidosis

United States, Canada, Spain, Israel, France, Australia, Denmark, Germany, Korea, Republic of, Greece, Netherlands, Brazil, Czechia, Italy, United Kingdom
AvenCell Europe GmbH
PHARMALOG Institut für klinische Forschung GmbH

Terminated

Dose-escalating Trial With UniCAR02-T Cells and PSMA Target Module (TMpPSMA) in Patients With Progressive Disease After Standard Systemic Therapy in Cancers With Positive PSMA Marker

Prostate Cancer

Germany
National Institute of Allergy and Infectious Diseases...
Rho Federal Systems Division, Inc.; Autoimmunity Centers of Excellence

Completed

COVID-19 Booster Vaccine in Autoimmune Disease Non-Responders

Systemic Lupus Erythematosus (SLE) | Multiple Sclerosis (MS) | Rheumatoid Arthritis (RA) | Juvenile Dermatomyositis (JDM) | Juvenile Idiopathic Arthritis (JIA) | Pemphigus Vulgaris | Systemic Sclerosis (SSc) | Pediatric SLE | Pediatric-Onset Multiple Sclerosis (POMS)

United States
CHU de Reims

Completed

Observational Study Assessing Outcomes, Treatment Patterns and Related Costs in Patients in Bullous Pemphigoid (EDP-PB)

Bullous Pemphigoid

France
M.D. Anderson Cancer Center
Novartis Pharmaceuticals

Completed

Everolimus (RAD001) as Therapy for Patients With Systemic Mastocytosis

Systemic Mastocytosis

United States
GlaxoSmithKline

Completed

Belimumab Assessment of Safety in SLE (BASE)

Systemic Lupus Erythematosus

United States, Ukraine, Taiwan, Bulgaria, Canada, Czechia, Estonia, Italy, Poland, Philippines, Korea, Republic of, Romania, Australia, Hong Kong, Portugal, Spain, Thailand, Peru, Argentina, Brazil, Mexico, Hungary, Russian Federation, Malays... and more
Hadassah Medical Organization
Weizmann Institute of Science

Completed

Asses the Anti-inflammatory Effects of Short Term Copaxone Therapy on Patients the Acute Decompensated Heart Failure (Copaxone)

Heart Failure | Inflammatory Response | Acute Decompensated Heart Failure | Cytokine Storm

Israel
Takeda

Completed

Triple Combination Therapy in High Risk Crohn's Disease (CD)

Crohn Disease

United States, Canada
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy in Treating Patients With AIDS-Related Lymphoma

Lymphoma

United States
Celularity Incorporated

Withdrawn

CYNK-001 IV and IC in Combination With IL2 in Surgical Eligible Recurrent GBM With IDH-1 Wild Type (CYNK001GBM02)

Glioblastoma | Glioblastoma Multiforme | Giant Cell Glioblastoma | Astrocytoma, Grade IV

United States
Assistance Publique - Hôpitaux de Paris
French Vasculitis Study Group

Active, not recruiting

Maintenance of Remission With Rituximab Versus Azathioprine for Newly-diagnosed or Relapsing Eosinophilic Granulomatosis With Polyangiitis. (MAINRITSEG)

Eosinophilic Granulomatosis With Polyangiitis

France
GlaxoSmithKline
Human Genome Sciences Inc., a GSK Company

Active, not recruiting

Pediatric Lupus Trial of Belimumab Plus Background Standard Therapy (PLUTO)

Systemic Lupus Erythematosus

Peru, United States, Spain, Argentina, United Kingdom, Poland, Canada, Russian Federation, Japan, Mexico
University of California, Los Angeles
Orchard Therapeutics; California Institute for Regenerative Medicine (CIRM)

Completed

Efficacy and Safety of the Cryopreserved Formulation of OTL-101 in Subjects With ADA-SCID

Severe Combined Immunodeficiency Due to ADA Deficiency

United States
Margarida Magalhaes-Silverman
National Cancer Institute (NCI)

Completed

Autologous Stem Cell Transplant Followed By Maintenance Therapy in Treating Elderly Patients With Multiple Myeloma

Stage I Multiple Myeloma | Stage II Multiple Myeloma | Stage III Multiple Myeloma | Primary Systemic Amyloidosis | Light Chain Deposition Disease | Extramedullary Plasmacytoma | Isolated Plasmacytoma of Bone

United States
GlaxoSmithKline

Completed

A Study to Evaluate the Efficacy and Safety of Belimumab Administered in Combination With Rituximab to Adult Subjects With Systemic Lupus Erythematosus (SLE) - BLISS-BELIEVE

Systemic Lupus Erythematosus

United States, Russian Federation, France, Spain, Korea, Republic of, Germany, Brazil, Netherlands, Canada, Mexico, Argentina
Rachel Jones
GlaxoSmithKline; Imperial College London; University College, London; Medical Research... and other collaborators

Active, not recruiting

Rituximab and Belimumab Combination Therapy in PR3 Vasculitis (COMBIVAS)

Granulomatosis With Polyangiitis | ANCA Associated Vasculitis

United Kingdom
Nada Magdy Mansour

Completed

A Pharmacoeconomic Study Comparing the Use of Mycophenolate Mofetil or Cyclophosphamide as Induction Therapy in Lupus Nephritis Patients in Egypt

Lupus Nephritis

Egypt
SCRI Development Innovations, LLC
Novartis; Genentech, Inc.

Completed

RT, Temozolomide, and Bevacizumab Followed by Bevacizumab/Everolimus in First-line Treatment of GBM

Glioblastoma Multiforme

United States

Search clinical trials for: Systemic Immunosuppressive Therapy

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