Search clinical trials for: T-cell stimulation

Total 11873 results

University of Kansas Medical Center
National Cancer Institute (NCI); Iovance Biotherapeutics, Inc.

Recruiting

Lifileucel With Reduced Dose Fludarabine/Cyclophosphamide Lymphodepletion and Interleukin-2 for the Treatment of Patients With Unresectable or Metastatic Melanoma

Metastatic Melanoma | Unresectable Melanoma | Pathologic Stage IIIC Cutaneous Melanoma AJCC v8 | Clinical Stage IV Cutaneous Melanoma AJCC v8

United States
Zhao Jun

Recruiting

Investigating the Biomarkers in Tumor and Peripheral Blood to Evaluate the Efficacy of Cancer Immunotherapy in Chest Cancer Patients

Esophageal Cancer | Lung Cancer

China
Immunophotonics, Inc.

Recruiting

Intratumoral Injection of IP-001 Following Thermal Ablation in Patients With CRC, NSCLC, and STS (INJECTABL-1)

Soft Tissue Sarcoma | Nonsmall Cell Lung Cancer | Metastatic Solid Tumor | Colon Cancer

France, United Kingdom, United States, Germany, Switzerland
Swiss Group for Clinical Cancer Research
Immunophotonics, Inc.

Recruiting

Intratumoral Injection of IP-001 Following Thermal Ablation in Patients With Advanced Solid Tumors.

Advanced Solid Tumors

Switzerland
University of Washington
Genentech, Inc.

Suspended

Polatuzumab Vedotin and Combination Chemotherapy for the Treatment of Untreated Aggressive Large B-cell Lymphoma

Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Aggressive Non-Hodgkin Lymphoma | Diffuse Large B-Cell Lymphoma, Not Otherwise Specified | EBV-Positive Diffuse Large B-Cell Lymphoma, Not Otherwise Specified | High Grade B-Cell Lymphoma, Not Otherwise Specified | T-Cell/Histiocyte-Rich... and other conditions

United States
M.D. Anderson Cancer Center
Bristol-Myers Squibb; National Cancer Institute (NCI); Iovance Biotherapeutics

Active, not recruiting

Autologous Tumor Infiltrating Lymphocytes MDA-TIL in Treating Patients With Recurrent or Refractory Ovarian Cancer, Colorectal Cancer, or Pancreatic Ductal Adenocarcinoma

Malignant Solid Neoplasm | Metastatic Colorectal Adenocarcinoma | Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8 | Platinum-Resistant Ovarian Carcinoma | Metastatic Pancreatic Ductal Adenocarcinoma | Metastatic Ovarian Carcinoma and other conditions

United States
Jonsson Comprehensive Cancer Center
California Institute for Regenerative Medicine (CIRM)

Terminated

Genetically Engineered PBMC and PBSC Expressing NY-ESO-1 TCR After a Myeloablative Conditioning Regimen to Treat Patients With Advanced Cancer (NYESO SCT)

Sarcoma | Unresectable Malignant Neoplasm | Locally Advanced Malignant Neoplasm | HLA-A*0201 Positive Cells Present | NY-ESO-1 Positive

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Specialized Blood Cell Transplants for Cancers of the Blood and Bone Marrow

Myeloproliferative Disorders | Acute Lymphoblastic Leukemia | Myelodysplastic Syndrome | Acute Myelogenous Leukemia | Chronic Myelogenous Leukemia

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Umbilical Cord Blood NK Cells, Rituximab, High-Dose Chemotherapy, and Stem Cell Transplant in Treating Patients With Recurrent or Refractory B-Cell Non-Hodgkin's Lymphoma

Mantle Cell Lymphoma | Recurrent Diffuse Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Refractory Indolent Adult Non-Hodgkin Lymphoma | Recurrent Follicular Lymphoma | Refractory Follicular Lymphoma | Recurrent Indolent Adult Non-Hodgkin Lymphoma

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

G-CSF and AMD3100 to Mobilize Stem Cells in Healthy Volunteers

Healthy

United States
Therapeutic Advances in Childhood Leukemia Consortium
GlaxoSmithKline; Novartis

Terminated

Trial of Nelarabine, Etoposide and Cyclophosphamide in Relapsed T-cell ALL and T-cell LL

Relapsed T-Cell Acute Lymphoblastic Leukemia | Relapsed T-Cell Lymphoblastic Lymphoma

United States, France, Canada, Australia, Austria, Italy, Netherlands
University of California, San Francisco
Washington University School of Medicine; Eisai Inc.

Terminated

Treatment of PTCL With Aggressive Induction Therapy Followed by Autologous SCT Using Denileukin Diftitox (Ontak)

Peripheral T-Cell Lymphoma

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Fludarabine, Bendamustine, and Rituximab in Treating Participants With Lymphoid Cancers Undergoing Stem Cell Transplant

Follicular Lymphoma | Mantle Cell Lymphoma | Marginal Zone Lymphoma | Chronic Lymphocytic Leukemia | Recurrent Diffuse Large B-Cell Lymphoma | CD20 Positive | T-Cell Non-Hodgkin Lymphoma

United States
Memorial Sloan Kettering Cancer Center

Terminated

T-cell Depleted Hematopoietic Stem Cell Boosts Without Conditioning for Poor Marrow Graft Function Following Allogeneic Hematopoietic Stem Cell Transplantation

Hematopoietic Stem Cell Transplant | Poor Marrow Graft Function

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy and Radiation Therapy in Treating Patients With Acute Lymphoblastic Leukemia That Has Relapsed in the CNS or Testes

Leukemia

United States, Canada, Australia, Switzerland, New Zealand
National Cancer Institute (NCI)

Completed

Interleukin-12 in Treating Patients With Previously Treated Non-Hodgkin's Lymphoma or Hodgkin's Disease

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma | Recurrent Adult Immunoblastic... and other conditions

United States
National Cancer Institute (NCI)

Terminated

Interleukin-12 and Interleukin-2 in Treating Patients With Mycosis Fungoides

Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma | Recurrent Mycosis Fungoides/Sezary Syndrome | Stage III Cutaneous T-cell Non-Hodgkin Lymphoma | Stage III Mycosis Fungoides/Sezary Syndrome | Stage IV Cutaneous T-cell Non-Hodgkin Lymphoma | Stage IV Mycosis Fungoides/Sezary Syndrome | Stage I... and other conditions

United States
Roswell Park Cancer Institute

Withdrawn

Mechanical Stimulation in Preventing Bone Density Loss in Patients Undergoing Donor Stem Cell Transplant

Primary Myelofibrosis | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma and other conditions
M.D. Anderson Cancer Center
Bayer

Terminated

Autologous and Allogenic Transplantation With Campath-1H for T-Cell Lymphoma

Lymphoma

United States
National Institutes of Health Clinical Center (CC)

Completed

Pilot Study: Effects of G-CSF on T Cell Function

Healthy

United States
Christoph Nissen

Not yet recruiting

Sleep Modulation to Treat Depression

Healthy | Major Depressive Disorder

Switzerland
The Cleveland Clinic
The Craig H. Neilsen Foundation

Recruiting

Rebuilding Inter-limb Transfer in Cervical SCI

Cervical Spinal Cord Injury

United States
Medical University of South Carolina
National Institute on Drug Abuse (NIDA)

Not yet recruiting

ACTION: Trial of Adding Buprenorphine, CBT, and TMS to Improve Outcomes of Long-Term Opioid Therapy for Chronic Pain (ACTION)

Chronic Pain | Opioid Withdrawal

United States
Yale University

Not yet recruiting

Using Virtual Reality Before Transcranial Magnetic Stimulation for the Treatment of OCD (VR-TMS)

Obsessive-Compulsive Disorder

United States
Fundació Tecnocampus Mataró-Maresme

Recruiting

Non-invasive Auricular Simulation for Exam Anxiety and Depression in University Students (AURITEST)

Stress | Insomnia | Anxiety

Spain
Ruijin Hospital

Not yet recruiting

Blinatumomab Maintenance After Allo-HSCT

High Risk Acute Lymphoblastic Leukemia
Brigham and Women's Hospital

Not yet recruiting

Spinal Cord Stimulation for Lower Extremity Function

Spinal Cord Injury
University of Malaga
Jorge Manuel Góngora Rodríguez

Not yet recruiting

Effects Obtained at Manual Function After Applying Anodic Transcranial Direct Current Stimulation (tCDS) in Children With Spastic Hemiparetic Cerebral Palsy (PeditCDS)

Hemiparetic Cerebral Palsy

Spain
Brigham and Women's Hospital

Not yet recruiting

Epidural Stimulation for Upper Extremity Function

Tetraplegia | Spinal Cord Injury Cervical
Xuanwu Hospital, Beijing

Not yet recruiting

Subiculum Electrical Stimulation for Temporal Lobe Epilepsy With Biliteral Hippocampus Sclerosis(SESTB)

Epilepsy, Drug Resistant

China
Fondazione Don Carlo Gnocchi Onlus
Istituto Italiano di Tecnologia; Istituto Nazionale di Ricovero e Cura per...

Not yet recruiting

Proof of Concept of Hybrid Robotics for Gait Rehabilitation of Persons Post-stroke (PoCH-Rehab)

Stroke Sequelae | Gait, Hemiplegic

Italy
Hangang Sacred Heart Hospital

Recruiting

Clinical Utility of Extracorporeal Shock Wave Therapy in Restoring Hand Function of Patients With Nerve Injury and Hypertrophic Scars Due to Burns

Burns | Hand Injuries | Extracorporeal Shock Wave Therapy

Korea, Republic of
Peking University Third Hospital

Recruiting

Electrical Phrenic Nerve Stimulation in Patients With VIDD

Diaphragms | Phrenic Nerves

China
Peking University First Hospital
Peking University Third Hospital; Peking University Cancer Hospital & Institute

Recruiting

A Study of Molecular Subtyping-based Therapeutic Strategies for Cutaneous T-cell Lymphoma (AMITY)

Cutaneous T Cell Lymphoma | Cutaneous T-Cell Lymphoma/Mycosis Fungoides

China
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Study and Modulation of Immune Responses in Primary and Metastatic Colon Cancers (I-COMET)

Colon Cancer | Peritoneal Carcinoma

France
Istanbul Medipol University Hospital

Recruiting

Cervical Manual Therapy and Vagus Nerve Stimulation in Patients With Nonspecific Neck Pain

Pain Syndrome

Turkey
Second Affiliated Hospital, School of Medicine,...
The First Affiliated Hospital of Anhui Medical University; Shanghai Mental... and other collaborators

Not yet recruiting

Multicenter iTBS Neuromodulation for PTSD Treatment (TMCP)

Posttraumatic Stress Disorder
University Hospital, Lille

Not yet recruiting

Evaluation of Autonomic Nervous System Changes in Response to Stimulation by Sacral Neuromodulation (ESTIME)

Sacral Neuromodulation | Bladder Hyperactivity
University of British Columbia
Providence Health & Services

Not yet recruiting

Validation and Usability Study of Intermittent Electrical Simulation in Management of Pressure Injuries Stages 1 and 2 (IESPI)

Pressure Injury
Savara Inc.

Not yet recruiting

Inhaled Molgramostim in Pediatric Participants With Autoimmune Pulmonary Alveolar Proteinosis (aPAP).

Autoimmune Pulmonary Alveolar Proteinosis

United States
Centrum Clinic IVF Center

Not yet recruiting

BEst Size for Ovulation Triggering in Poseidon 4 Patients (BEST 4 Study) (BEST)

Fertilization | Fertilization in Vitro
University Medical Center Groningen

Not yet recruiting

Neurophysiological Effects of Transcutaneous Electrical Nerve Stimulation in Persons With MS

Multiple Sclerosis | Fatigue | Walking, Difficulty
Tianjin Medical University Cancer Institute and...

Recruiting

CMOEP in the Treatment of Untreated Peripheral T-cell Lymphoma

Peripheral T Cell Lymphoma

China
Centre Hospitalier Régional Metz-Thionville

Not yet recruiting

Pilot Study on the Acceptability of Auricular Vagus Nerve Neurostimulation in Adolescents (NEUROMUTE)

Psychiatric Disorder

France
Butler Hospital
National Institute on Drug Abuse (NIDA)

Recruiting

tDCS to Decrease Opioid Relapse (UH3)

Opioid Use Disorder

United States
Emory University

Recruiting

AB Gait Estim Neurophysiology

Gait

United States
Neuronetics

Recruiting

Symptom Evaluation Following Repetitive Transcranial Magnetic Stimulation (SET)

Neurologic Symptoms

United States
Shirley Ryan AbilityLab

Not yet recruiting

Impact of Sensory Electrical Stimulation on Sensation and Tremor

Essential Tremor | Healthy Individuals

United States
Medical University of South Carolina

Recruiting

tFUS Induced Transient Scotoma for Individual Dosing

Healthy

United States
Universitaire Ziekenhuizen KU Leuven
Research Foundation Flanders

Recruiting

Connectivity and Neural Signatures of Consciousness in Unresponsive States (CONSCIUS)

Seizures | Traumatic Brain Injury | Consciousness Disorders | Acute Brain Injury

Belgium

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