Search clinical trials for: Thrombopoietin receptor agonist

Total 25883 results

Institute of Hematology & Blood Diseases Hospital...

Not yet recruiting

Lusutrombopag in the Treatment of Immune Thrombocytopenia (ITP)

Immune Thrombocytopenia | Idiopathic Thrombocytopenic Purpura

China
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...

Recruiting

Prospective Evaluation of Diagnosis and Treatment of Patients With Autoimmune Cytopenias Including Autoimmune Hemolytic Anemia, Immune Thrombocytopenia, and Chronic Idiopathic/Autoimmune Neutropenia (AIHA ITP CIN)

Myelodysplastic Syndromes | Immune Thrombocytopenia | Autoimmune Hemolytic Anemia | Cold Agglutinin Disease | Autoimmune Neutropenia | Chronic Idiopathic Neutropenia

Italy
The First Affiliated Hospital of Soochow University

Not yet recruiting

Decitabine for Poor Graft Function Post Allo-HSCT

Poor Graft Function
Assiut University

Not yet recruiting

Safety of Oral Thrombopoietin Receptor Agonist in Pediatric Chronic ITP

Thrombopoietin Receptor Agonist
Hanny Al-Samkari, MD
Swedish Orphan Biovitrum

Recruiting

Avatrombopag vs. Placebo for CIT in GI Malignancies (ACT-GI)

Gastrointestinal Neoplasms | Gastrointestinal Cancer | Chemotherapy-Induced Thrombocytopenia

United States
The First Affiliated Hospital of Soochow University

Not yet recruiting

Decitabine and Umbilical Cord Blood for Poor Graft Function Post Allo-HSCT

Poor Graft Function
Peking University People's Hospital
Qilu Hospital of Shandong University; Beijing Tongren Hospital; Beijing Hospital and other collaborators

Not yet recruiting

Zanubrutinib and Eltrombopag as Second-line Treatment in Adults With Primary Immune Thrombocytopenia

Immune Thrombocytopenia

China
European Research Consortium on ITP
Fondazione Progetto Ematologia

Completed

Evaluation of the Use of Thrombopoietin Receptor Agonists in Adults With Primary ITP in Europe

Primary Immune Thrombocytopenia (ITP)

Spain, Switzerland, United Kingdom, Italy, France, Norway
AO GENERIUM

Completed

Comparative Study of Clinical Efficacy and Safety of GNR-069 and Nplate in Patients With ITP

Idiopathic Thrombocytopenic Purpura

Russian Federation
AO GENERIUM

Enrolling by invitation

Study of the Safety and Immunogenicity of Long-term GNR-069 Therapy in ITP Patients

Idiopathic Thrombocytopenic Purpura

Russian Federation
Swedish Orphan Biovitrum

Active, not recruiting

An Observational, Multicenter Study to Evaluate the Use and Effectiveness of Doptelet® in Patients With ITP (ADOPT)

Immune Thrombocytopenia | ITP

Croatia, Czechia, Germany, Italy, Netherlands, Norway, Spain, Switzerland, United Kingdom
Novartis Pharmaceuticals

Completed

A Study to Assess Efficacy and Safety of Eltrombopag in Combination With a Short Course of Dexamethasone in Patients With Newly Diagnosed ITP (XPAG-ITP)

Immune Thrombocytopenia (ITP)

Germany
University Children's Hospital Basel
Novartis Pharmaceuticals; Stiftung zur Förderung medizinischer und biologischer... and other collaborators

Active, not recruiting

Immunomodulation With Eltrombopag in ITP (iROM2)

Primary Immune Thrombocytopenia (ITP)

Switzerland
National Heart, Lung, and Blood Institute (NHLBI)

Completed

A Pilot Study of a Thrombopoietin-Receptor Agonist, Eltrombopag, in Patients With Low to Int-2 Risk Myelodysplastic Syndrome (MDS)

Myelodysplastic Syndromes | Thrombocytopenia

United States
M.D. Anderson Cancer Center
GlaxoSmithKline

Completed

Phase II Eltrombopag in Chronic Lymphocytic Leukemia (CLL)

Leukemia | CLL

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

A Pilot Study of the Thrombopoietin-Receptor Agonist Eltrombopag in Refractory Aplastic Anemia Patients

Thrombocytopenia | Anemia, Aplastic | Anemia, Hypoplastic

United States
Assistance Publique - Hôpitaux de Paris

Unknown

Rate of Prolonged Response After Stopping Thrombopoietin-receptor Agonists Treatment in ITP (STOP-AGO)

Persistent or Chronic ITP

France
Novartis Pharmaceuticals

Completed

A Safety and Efficacy Study of Eltrombopag in Subjects With AML

Acute Leukaemia

United States, Belgium, Canada, Australia, Greece, Israel, Russian Federation, Hungary, Korea, Republic of, Poland
Novartis Pharmaceuticals

Completed

A Long-term Safety Study of Eltrombopag in Pediatric Patients With Chronic Immune (Idiopathic) Thrombocytopenic Purpura (ITP)

Purpura, Thrombocytopenic, Idiopathic

Russian Federation
Gruppo Italiano Malattie EMatologiche dell'Adulto

Unknown

Response Rate and Duration After Discontinuation Thrombopoietin Receptor Agonists Primary Immune Thrombocytopenia

Immune Thrombocytopenia

Italy
GlaxoSmithKline

Completed

Clinical Evaluation of Eltrombopag in Chronic Idiopathic Thrombocytopenic Purpura (ITP)

Purpura, Thrombocytopenic, Idiopathic | Idiopathic Thrombocytopenic Purpura

Japan
GlaxoSmithKline

Completed

Eltrombopag Treatment of Thrombocytopenia in Subjects With Advanced Myelodysplastic Syndrome (MDS) or Secondary Acute Myeloid Leukemia After MDS (sAML/MDS)

Myelodysplastic Syndrome

Puerto Rico, United States, Taiwan, Germany, Denmark, Hong Kong, Korea, Republic of, France, United Kingdom, Italy, Brazil
GlaxoSmithKline

Completed

SB-497115 (Oral Thrombopoietin Receptor Agonist) Versus Placebo In Adult Cancer Patients Receiving Chemotherapy

Thrombocytopaenia

Spain, Taiwan, Bulgaria, United States, Argentina, Russian Federation, Germany, Korea, Republic of, Austria, India, Italy, United Kingdom, Poland, Romania, Ukraine, Hungary, Peru, Czech Republic, Mexico
GlaxoSmithKline

Completed

LENS - Long-term Eltrombopag Observational Study (LENS)

Purpura, Thrombocytopaenic, Idiopathic

United States, Bulgaria, Italy, Peru, Russian Federation, Canada, France, Germany, Hong Kong, Spain, Sweden, United Kingdom, Hungary, Poland, Ukraine, Czech Republic, India, Australia, Tunisia, Puerto Rico, Pakistan
Weifeng Tu

Unknown

Effect of Dexmedetomidine for Postoperative Intravenous Patient Controlled Analgesia

Patient-Controlled Analgesia

China
GlaxoSmithKline

Completed

A Longitudinal 2-year Bone Marrow Study of Eltrombopag in Previously Treated Adults, With Chronic Immune (Idiopathic) Thrombocytopenic Purpura (ITP)

Purpura, Thrombocytopaenic, Idiopathic

Italy, Germany, Hong Kong, Korea, Republic of, United States, Pakistan, Russian Federation, India, Czech Republic, Hungary, France
Nordic MDS Group
GlaxoSmithKline

Completed

Safety Study of Eltrombopag Combined With Azacitidine to Treat Myelodysplastic Syndrome (MDS) (NMDSG10A)

Thrombocytopenia | Myelodysplastic Syndrome

Sweden
GlaxoSmithKline

Completed

SB-497115 (Oral Thrombopoietin Receptor Agonist) Versus Placebo In Adults With Refractory Immune Thrombocytopenic Purpura (ITP)

Purpura, Thrombocytopaenic, Idiopathic

Thailand, Korea, Republic of, United Kingdom, New Zealand, Germany, Greece, Hong Kong, Pakistan, Poland, Romania, Russian Federation, Slovenia, Taiwan
Henri Mondor University Hospital
Paris 12 Val de Marne University

Completed

Eltrombopag and Romiplostim Used Alternatively in Patients With Immune Thrombopenia (ITP): Efficacy and Safety.

Immune Thrombocytopenia | Thrombopoietin Receptor Agonist
GlaxoSmithKline

Completed

SB497115 (Oral Thrombopoietin Receptor Agonist) Versus Placebo In Adults With Thrombocytopenia Due To Hepatitis C

Hepatitis C | Hepatitis C, Chronic | Thrombocytopenia

United States, Germany, France, Puerto Rico, United Kingdom
University of KwaZulu

Not yet recruiting

Anti-Inflammatory Reliever South Africa (AIRSA001)

Asthma
Henry M. Jackson Foundation for the Advancement...
Uniformed Services University of the Health Sciences; Brooke Army Medical Center

Not yet recruiting

Ketamine for Sedation in Severe Traumatic Brain Injury (Ketamine)

Intracranial Hypertension | Severe Traumatic Brain Injury | Intracranial Hemorrhage, Hypertensive
Ain Shams University

Not yet recruiting

The Effect of Adding Either Propofol or Ketamine to Magnesium and Lidocaine Infusions in Nasal Surgeries.

Intraoperative Bleeding

Egypt
National Cancer Institute (NCI)

Not yet recruiting

Somatostatin-Receptors (SSTR)-Agonist [212Pb]VMT-alpha-NET in Metastatic or Inoperable SSTR+ Gastrointestinal Neuroendocrine Tumor and Pheochromocytoma/Paraganglioma Previously Treated With Systemic Targeted Radioligand Therapy

Pheochromocytoma | Somatostatin Receptor Positive | Paragangliomas | Gastrointestinal Neuroendocrine Tumors

United States
Universidad de Almeria
Leiden University Medical Center; ETH Zurich (Switzerland)

Not yet recruiting

Deciphering a Novel and Unique Brown Adipose Tissue Depot in Women (DEBATE)

Cardiometabolic Diseases

Spain
Stanford University
American Heart Association

Not yet recruiting

Efficacy of Targeted Medical Therapy in Angina and Nonobstructive Coronary Arteries (MVP-ANOCA)

Angina Pectoris | Microvascular Angina | Vasospastic Angina | Myocardial Bridge of Coronary Artery

United States
Bostal Drug Delivery Co., Ltd

Not yet recruiting

A Study to Evaluate Safety, Tolerability and pK of Semaglutide ER Injectable Suspension in Healthy, Adult Human Subjects

Diabetes Mellitus, Type 2
AstraZeneca
Premier HealthCare Solutions Inc.

Recruiting

Combination Short-Acting BroNchodilator and Inhaled Corticosteroid Rescue Therapy on Health Outcomes in Routine Care (ANCHOR)

Asthma

United States
Benha University

Recruiting

Articaine Plus Dexmedetomidine in Supraclavicular Block

Post Operative Pain, Acute

Egypt
Jens D Hove, MD,PHD

Recruiting

Effect of Weight Loss on Physical and Cardiac Performance in People With Obesity and Heart Failure (FIT-HF)

Obesity | Weight Loss | Chronic Heart Failure | Heart Failure With Reduced Ejection Fraction

Denmark
Icahn School of Medicine at Mount Sinai

Not yet recruiting

Intrathecal Dexmedetomidine vs Epinephrine

Cesarean Section | Anesthesia, Spinal

United States
Acepodia Biotech, Inc.

Not yet recruiting

ACE2016 in Adult Subjects With Locally Advanced or Metastatic Solid Tumors Expressing Epidermal Growth Factor Receptor (EGFR)

Metastatic Solid Tumor | Locally Advanced Solid Tumor

United States
Anqing Municipal Hospital

Recruiting

The Effect of Dexmedetomidine and Esketamine Combined Infusion Quality of Sleep Undergoing Modified Radical Mastectomy

Dexmedetomidine Plus Esketamine Affect Postoperative Sleep Quality

China
Theodor Bilharz Research Institute

Recruiting

The Effects of Different Loading Doses of Dexmedetomidine on The Bispectral Index-Guided Propofol Sedation in Patients Undergoing Advanced Upper Gastrointestinal Endoscopic Procedures: A Randomized Control Study

Procedural Sedation | GIT Endoscopy

Egypt
Fujian Provincial Hospital
Fujian Maternity and Child Health Hospital; Fujian Children's Hospital

Not yet recruiting

Intranasal Dexmedetomidine Versus Oral Midazolam Premedication for Postoperative Negative Behavior Changes in Children

Behavior Problem
Axsome Therapeutics, Inc.

Recruiting

Elucidating TAAR-1, Dopamine, and Norepinephrine in Binge Eating Disorder Using Solriamfetol (ENGAGE)

Binge-Eating Disorder

United States
Yale University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Novo...

Not yet recruiting

Obesity Complicating Type 1 Diabetes: GLP-1 Analogue Anti-obesity Treatment

Obesity | Diabetes type1

United States
Muhammad Ilyas

Not yet recruiting

Impact of Intrathecal vs Intravenous Dexmedetomidine

Nausea and Vomiting, Postoperative
Assiut University

Not yet recruiting

Dexmeditomedine as an Adjuvant to Levobupivacaine in Transversus Thoracis Plane Block on the Management of Post-sternotomy Pain in Open-heart Surgeries

Pain, Postoperative
Centre for Human Drug Research, Netherlands

Recruiting

Deep Phenotyping of Cutaneous Lupus Erythematosus

Cutaneous Lupus Erythematosus

Netherlands

Search clinical trials for: Thrombopoietin receptor agonist

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