Search clinical trials for: Toll-like receptors

Total 516 results

Yale University
National Institute of Allergy and Infectious Diseases (NIAID)

Recruiting

Systems Investigation of Vaccine Responses in Aging and Frailty

Influenza

United States
University of Göttingen
King's College London; Università degli Studi di Brescia

Recruiting

Epigenetics in Lupus Nephritis (Epi_LN)

Systemic Lupus Erythematosus | Lupus Nephritis

Germany
Hisar Intercontinental Hospital

Completed

Testicular Torsion

Testicular Torsion and TLR 4 Was Investigated
I.M. Sechenov First Moscow State Medical University

Completed

Evaluation of the Effect of IHHT on Vascular Stiffness and Elasticity of the Liver Tissue in Patients With MS.

Metabolic Syndrome | Vascular Stiffness | Liver Fibroses | Trimethylamine N-oxyde | Toll-like Receptors

Russian Federation
Cengiz Gokcek Women's and Children's Hospital

Completed

Analyses of Interleukin-6, Presepsin and Pentraxin-3 in the Diagnosis and Severity of Late-onset Preeclampsia (Presepsin&PE)

Preeclampsia

Turkey
GlaxoSmithKline

Withdrawn

A Safety and Efficacy Study of Intranasal GSK2245035 in Adults With Allergic Asthma

Asthma
University of Southern Denmark
Danish Cancer Society

Completed

Diet, Genes and Colorectal Cancer - With Focus on Toll-like Receptor Polymorphisms

Colorectal Cancer
VA Puget Sound Health Care System
Novartis Pharmaceuticals; University of Washington

Completed

Innate Immune Response in COPD

Inflammation | Pulmonary Disease, Chronic Obstructive | Bronchitis, Chronic | Immunity, Innate | Toll-Like Receptors

United States
Medical College of Wisconsin

Completed

Placental and Cord Blood Markers Associated With Premature Birth and Disorders of Premature Birth in Newborn Infants

Premature Birth

United States
UMC Utrecht
European Association of Cardiothoracic Anaesthesiologists

Completed

Inflammatory Response During Anesthesia and Surgery (IRAS)

Myocardial Ischemia | Systemic Inflammatory Response Syndrome

Netherlands
University of Aarhus
Aarhus University Hospital

Unknown

Immune Profile and Complication Risk in Type 2 Diabetes (IMPACT)

Diabetes Mellitus, Type 2

Denmark
University of Thessaly

Unknown

Ventilator-Associated Pneumonia (VAP) in Intensive Care Unit (ICU)

Ventilator-Associated Pneumonia

Greece
University of Thessaly

Unknown

Bacteremia in Intensive Care Unit (ICU)

Bacteremia and Sepsis | Toll-Like-Receptors (TLRs)

Greece
University Hospital, Geneva

Not yet recruiting

Investigation of the Evolution of Gastric Emptying by Gastric Ultra Sonography in Patients Treated With GLP-1 Receptor Agonists on a 7 Days Pausing Period.

Diabetes Mellitus, Type 2 | Anesthesia | Pulmonary Aspiration of Gastric Contents
Universitaire Ziekenhuizen KU Leuven
Eli Lilly and Company; Kom Op Tegen Kanker; Teva Pharma

Recruiting

Bicalutamide and Abemaciclib in Inoperable or Metastatic Androgen Receptor-positive Triple-negative Breast Cancer (ABBICAR)

Triple Negative Breast Neoplasms

Belgium
National Cancer Institute (NCI)

Not yet recruiting

Anti-CD19 Chimeric Antigen Receptor T-Cell Immunotherapy for Chronic Lymphocytic Leukemia (CLL)

Leukemia, Lymphocytic, Chronic, B-Cell | B-Cell Chronic Lymphocytic Leukemia | B-Lymphocytic Leukemia, Chronic

United States
Barretos Cancer Hospital
Fundação de Amparo à Pesquisa do Estado de São Paulo; Farmoquimica S.A.; Hospital...

Not yet recruiting

Clinical Outcome and Biomarkers for Predicting Immunological Response in Patients Treated With Imiquimod

Biomarkers | HSIL, High-Grade Squamous Intraepithelial Lesions | Vaginal Microbiome
Assiut University

Recruiting

Memantine Hydrochloride for Treatment of Cognitive Dysfunction Due to Traumatic Brain Injury

Treatment of Posttraumatic Cognitive Dysfunction

Egypt
OX2 Therapeutics

Recruiting

CD200AR-L and Allogeneic Tumor Lysate Vaccine Immunotherapy for Recurrent HGG and Newly Diagnosed DMG/DIPG in Children and Young Adults

Diffuse Midline Glioma, H3 K27M-Mutant | Recurrent High Grade Glioma

United States
Centre Hospitalier Universitaire de Saint Etienne

Recruiting

The Role of Platelet TLRs in Platelet Activation During VTE (ROT-PLAT-VTE)

Venous Thromboembolism

France
Maastricht University Medical Center

Recruiting

Real-world Evaluation of Diagnostic and Treatment Strategies in Low-Risk Basal Cell Carcinoma (REDT-BCC)

Basal Cell Carcinoma

Netherlands
National Cancer Institute (NCI)

Recruiting

Autologous T-cells Genetically Engineered to Express Receptors Reactive Against KRAS Mutations in Conjunction With a Vaccine Directed Against These Antigens in Participants With Metastatic Cancer

Breast Cancer | Colorectal Cancer | Ovarian Cancer | Non-Small Cell Lung Cancer | Gastrointestinal Cancer | Genitourinary Cancer | Metastatic Solid Cancers

United States
Fondazione Policlinico Universitario Agostino Gemelli...

Recruiting

Estrogen Receptors and HER2 Levels' Expression in Luminal Metastatic Breast Cancer (CYCLHER)

Advanced Breast Carcinoma

Italy
Fondazione Policlinico Universitario Agostino Gemelli...

Not yet recruiting

Hyperlactacidemia in Major Abdominal Surgery and Monocarboxylate Receptors (NETTUNO)

Postoperative Complications | Surgical Procedure, Unspecified | Hyperlactatemia | Abdomen Disease

Italy
Lakehead University

Recruiting

Over-the-Counter Antihistamines & Heat Stress

Allergic Rhinitis | Heat Illness | Heat Injury | Sudomotor Sympathetic Dysfunction

Canada
Anna Stanhewicz, PhD

Recruiting

Balance of Angiotensin II Receptors in Vessel Function After Preeclampsia

Preeclampsia

United States
University Hospital, Strasbourg, France

Recruiting

Hematological Effects of Atypical Antipsychotics (AAPs) in a Geriatric Population: What is the Role of 5-HT2 Receptors (AAPs)

Neutropenia

France
Fred Hutchinson Cancer Center
Bristol-Myers Squibb

Not yet recruiting

Autologous T Cells Lentivirally Transduced to Express L1CAM-Specific Chimeric Antigen Receptors in Treating Patients With Locally Advanced and Unresectable or Metastatic Small Cell Neuroendocrine Prostate Cancer

Stage IV Prostate Cancer AJCC v8 | Prostate Carcinoma | Stage III Prostate Cancer AJCC v8 | Prostate Small Cell Neuroendocrine Carcinoma

United States
National Institute of Allergy and Infectious Diseases...
Gilead Sciences; University of Oxford

Recruiting

Evaluation of Safety, Immunogenicity and Efficacy of a Triple Immune Regimen in Adults Initiated on ART During Acute HIV-1

HIV-1-infection

United States, Brazil
Cancer Research UK
Aleta BioTherapeutics

Recruiting

A Phase I/II Trial of ALETA-001 for the Treatment of Participants With B-cell Malignancies

Lymphoma, Follicular | Lymphoma, B-Cell | Lymphoma, Large B-Cell, Diffuse | Lymphoma, Non-Hodgkin | Lymphoma, Mantle-Cell

United Kingdom
Fred Hutchinson Cancer Center
Affini-T Therapeutics, Inc.

Recruiting

Autologous CD8+ and CD4+ Transgenic T Cells Expressing High Affinity KRASG12V Mutation-Specific T Cell Receptors (FH-A11KRASG12V-TCR) in Treating Patients With Metastatic Pancreatic, Colorectal and Non-Small Cell Lung Cancers With KRAS G12V Mutations

Metastatic Lung Non-Small Cell Carcinoma | Stage IV Pancreatic Cancer AJCC v8 | Metastatic Pancreatic Adenocarcinoma | Metastatic Colorectal Adenocarcinoma | Stage IV Lung Cancer AJCC v8 | Stage IV Colorectal Cancer AJCC v8

United States
Assistance Publique - Hôpitaux de Paris

Recruiting

Fetal Cell Receptors Repertoire (MoreCCR)

Venous Ulcer | Diabetic Ulcer | Sickle Cell Ulcer | Post-partum Women | Mixed Ulcer

France
University of Alberta

Recruiting

Sympathetic Neurovascular Transduction: Role of Adrenergic Receptors and Sex Differences (STARS)

Vasodilation | Vasoconstriction

Canada
Pharmazz, Inc.

Recruiting

Study to Assess the Safety and Efficacy of Sovateltide in Patients With Acute Cerebral Ischemic Stroke

Acute Cerebral Ischemia

India
Tomsk National Research Medical Center of the Russian...
Uppsala University

Recruiting

Molecular Imaging of Gastrin Releasing Peptide Receptors Using Labeled Technetium-99m DB8

Breast Cancer | Prostate Cancer

Russian Federation
Anna Stanhewicz, PhD

Recruiting

Sensitivity of Angiotensin II Type II Receptors in Women Following Preeclampsia

Preeclampsia Postpartum

United States
Assiut University

Not yet recruiting

Role of LILRA3 in Ankylosing Spondylitis and Axial Psoriatic Patients

Autoimmune Diseases
Northwestern University

Recruiting

Combining Topical Imiquimod With Local Radiotherapy for Treatment of Mycosis Fungoides

Mycosis Fungoides

United States
InCor Heart Institute

Recruiting

The Effects of Resveratrol on Sirtuins and Apoptosis Biomarkers (RE-AGES)

Coronary Artery Disease | Menopause | Endothelial Dysfunction

Brazil
SURGE Therapeutics

Recruiting

A Study of STM-416 Administered to Patients Undergoing TURBT for Recurrent Bladder Cancer

Non-muscle-invasive Bladder Cancer

United States
Pharmazz, Inc.

Not yet recruiting

Assess the Safety and Efficacy of Sovateltide in Patients With Acute Cerebral Ischemic Stroke

Acute Ischemic Stroke | Cerebral Stroke
Christian Hinrichs

Recruiting

E7 TCR-T Cell Immunotherapy for Human Papillomavirus (HPV) Associated Cancers

Cervical Cancer | HPV-Related Malignancy | Metastatic Cancer | Anal Cancer | Oropharynx Cancer | Vaginal Cancer | HPV-Related Carcinoma | HPV-Related Cervical Carcinoma | HPV Positive Oropharyngeal Squamous Cell Carcinoma | Penile Cancer | HPV-Related Adenocarcinoma | HPV-Related Adenosquamous Carcinoma | HPV-Related... and other conditions

United States
China Medical University Hospital

Recruiting

The Roles of Human Microbiome and Vitamin D in the Development of Childhood Allergic Diseases

Pediatric

Taiwan
Centre Antoine Lacassagne

Recruiting

Study to Determine the Safety and Efficacy of Ribociclib in Combination With Hormone Therapy and Hypofractionated Radiotherapy in Breast Cancer, With Positive Hormone Receptors and Negative HER2 Status, in Newly Diagnosed, Not Immediately Operable Elderly Patient (CALHYS) (CALHYS)

HER2 Negative Breast Cancer Not Immediately Operated

France
Perspective Therapeutics

Recruiting

MC1R-targeted Alpha-particle Therapy Trial in Adults With Advanced Melanoma

Metastatic Melanoma | Melanoma (Skin) | Mucosal Melanoma | Melanoma Stage IV | Melanoma Stage III | Melanoma, Uveal

United States
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Recruiting

Study of M5049 in DM and PM Participants (NEPTUNIA)

Dermatomyositis | Polymyositis

United States, Italy, Spain, Greece, Czechia, United Kingdom, Poland
Janssen Pharmaceutical K.K.

Recruiting

A Study of Erdafitinib Intravesical Delivery System in Japanese Participants With Bladder Cancer (TAR-210)

Urinary Bladder Neoplasms | Receptors, Fibroblast Growth Factor

Japan
Cerevel Therapeutics, LLC

Recruiting

Positron Emission Tomography (PET) Trial to Evaluate Target Occupancy of CVL-354 at Kappa and Mu Opioid Receptors in Brain Following Oral Dosing

Opioid Use Disorder

United States
Merck Healthcare KGaA, Darmstadt, Germany, an affiliate...

Recruiting

The Willow LTE Study With M5049 in Participants With SCLE, DLE and/or SLE (WILLOW LTE)

Systemic Lupus Erythematosus

United States, Spain, China, Korea, Republic of, Argentina, Bulgaria, Chile, Greece, Japan, Mauritius, Mexico, Moldova, Republic of, Poland, South Africa, Australia, Colombia, Philippines, Serbia
Yonsei University

Recruiting

Fibroblast Growth Factor (FGFs) / Fibroblast Growth Factor Receptor (FGFRs) Genetic as a Second-line Therapy for Recurrent / Progressive Gastric Cancer With INCB054828 and Paclitaxel a Study to Evaluate the Safety and Efficacy of Combination Therapy.

Fibroblast Growth Factors (FGFs)/Fibroblast Growth Factor Receptors (FGFRs) Genetic Aberration Gastric Cancer, INCB054828, Paclitaxel

Korea, Republic of

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