Search clinical trials for: Twice a year treatment

Total 494550 results

Noguchi Memorial Institute for Medical Research
Ghana Health Services

Completed

Twice Yearly Treatment for the Control of LF

Lymphatic Filariasis | Helminth Infection

Ghana
Eli Lilly and Company

Terminated

A Comparison of Two Treatment Strategies in Older Participants With Type 2 Diabetes Mellitus (T2DM) (IMPERIUM)

Diabetes Mellitus, Type 2

United States, Puerto Rico, Germany, United Kingdom, Austria
ANRS, Emerging Infectious Diseases
Institut National de la Santé Et de la Recherche Médicale, France; University... and other collaborators

Completed

Evaluation of Simplified Antiretroviral Treatment Strategies in HIV Infected Children Treated by Antiretroviral (ARV) Before One Year of Age

HIV Infections

Burkina Faso, Côte D'Ivoire
AstraZeneca
Bristol-Myers Squibb

Completed

Evaluation of Dapagliflozin Taken Twice-daily

Type 2 Diabetes

South Africa, Germany, Hungary, Romania, Slovakia, Switzerland, Ukraine
Zealand University Hospital
Tampere University Hospital

Not yet recruiting

Surgical Versus Non-surgical Treatment of Displaced Proximal Humerus Fracture in Adults Aged 50 to 65 Years (PHF50-65)

Shoulder Fractures | Proximal Humeral Fracture

Finland, Denmark
Sanofi

Recruiting

A Study to Evaluate the Treatment Response and Safety of Two Dose Regimens of Subcutaneous Amlitelimab Monotherapy Compared With Treatment Withdrawal in Participants Aged 12 Years and Older With Moderate-to-severe Atopic Dermatitis (ESTUARY)

Dermatitis Atopic

United States
Salma Hassan Widatalla Omar

Not yet recruiting

Assessment of the Occlusal Characteristics and Orthodontic Treatment Needs for Egyptian Children( 6-12)years Old

Occlusion
Jaeb Center for Health Research
National Eye Institute (NEI); Pediatric Eye Disease Investigator Group

Not yet recruiting

Dichoptic Treatment for Amblyopia in Children 4 to 7 Years of Age (ATS23)

Amblyopia
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Evaluation of the Effectiveness of Hormonal Treatment in Adolescents Suffering From Gender Dysphoria (TRANSADO)

Cross Sex Hormonal Treatment in Adolescents With Gender Dysphoria
Fudan University

Recruiting

Chemotherapy Omission in ER+/HER2- Breast Cancer With 1-3 Positive Lymph Nodes Receiving Extended Adjuvant Abemaciclib (Rainbow)

Breast Cancer

China
Hospices Civils de Lyon

Not yet recruiting

Exploring Food Rejection Dispositions as Potential Risk Factors for Undernutrition in Hospitalized Children Aged 2 to 8 (MEDIALIME)

Undernutrition

France
University Hospital, Strasbourg, France

Not yet recruiting

Effect of One Year Elexacaftor-tezacaftor-ivacaftor Treatment (DIATRIM)

Cystic Fibrosis
Rui-hua Xu, MD, PhD

Not yet recruiting

A Phase II Study of Surufatinib Combined With Camrelizumab and mFOLFOX6 as Second-line Treatment for Advanced PRAD

Advanced Pancreatic Cancer

China
Nantes University Hospital

Recruiting

Prospective Multicenter Randomized and Controlled Study Evaluating the Benefit of Early Pulmonary Vein Isolation Compared to Usual Treatment in Patients Aged Over 75 Years and Presenting With Atrial Fibrillation (EDearly AF)

Atrial Fibrillation

France
University of Yalova

Recruiting

The Effect of Breathing Exercise on Sleep and Stress Levels in Women With Breast Cancer Receiving Chemotherapy Treatment

Women Receiving Chemotherapy | 18 Years of Age and Above | Women With High Stress Levels | Women With Poor Sleep Quality

Turkey
University Hospital of Cologne
Albert Einstein College of Medicine; Monash University; The Alfred; Johann Wolfgang... and other collaborators

Not yet recruiting

PrognostICate- Study:Prognostication of ICU- and Ventilator- Days Over the Next Years Until 2040 (PrognostICate)

ICU Admission
City of Hope Medical Center
National Cancer Institute (NCI)

Not yet recruiting

225Ac-DOTA-Anti-CD38 Daratumumab Monoclonal Antibody With Fludarabine, Melphalan and Total Marrow and Lymphoid Irradiation as Conditioning Treatment for Donor Stem Cell Transplant in Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia and Myelodysplastic Syndrome

Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Myelodysplastic Syndrome

United States
CeraRoot SL

Recruiting

5-Years PMCF Study of Ceramic Dental Implants One-piece Versus Two-piece. (240101)

Tooth Loss | Edentulism

Spain, United States
GlaxoSmithKline

Not yet recruiting

A Study to Assess and Compare Safety and Tolerability of 3 Months Treatment With Salbutamol Administered Via MDI Containing Propellant HFA-152a or HFA-134a in Participants 12 Years of Age and Older With Asthma

Asthma

Argentina, United States, Canada, Panama, Greece, France, Poland, Italy, United Kingdom
Travere Therapeutics, Inc.

Recruiting

A Study to Investigate Efficacy and Safety of Pegtibatinase Compared With Placebo in Participants ≥12 to ≤65 Years of Age With Classical Homocystinuria (HCU) Due to Cystathionine Beta Synthase Deficiency Receiving Standard of Care Treatment (HARMONY)

Homocystinuria

United States
Manuel Coelho da Rocha

Not yet recruiting

Tailored vs. Empirical Helicobacter Pylori Infection Treatment

Helicobacter Pylori Infection

Portugal
PETHEMA Foundation

Not yet recruiting

Treatment Protocol for Newky Diagnosed Adult Ph Positive ALL (LALPh2022)

Lymphoblastic Leukemia | Adult ALL | Philadelphia-Positive ALL
Massachusetts General Hospital
Foundation Medicine

Recruiting

Use of Serial Plasma NGS as a New Efficacy Metric to Guide Immunotherapy Treatment Discontinuation

Melanoma | Non-small Cell Lung Cancer

United States
Sanofi

Recruiting

A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab Monotherapy Compared With Placebo in Participants Aged 12 Years and Older With Moderate-to-severe Atopic Dermatitis (COAST 1)

Dermatitis Atopic

Israel, Chile, Australia, United States, Canada, Korea, Republic of, Taiwan, China
Epion Therapeutics

Recruiting

Epithelium-On Corneal Cross-linking in Subjects 8 to 45 Years of Age With Keratoconus (Apricity-A)

Keratoconus

United States
Epion Therapeutics

Recruiting

Epithelium-On Corneal Cross-linking in Subjects 8 to 45 Years of Age With Keratoconus (Apricity-B)

Keratoconus

United States
PersonGen BioTherapeutics (Suzhou) Co., Ltd.
Anhui Provincial Hospital

Not yet recruiting

UTAA09 Injection in the Treatment of Relapsed/Refractory Hematolymphatic Malignancies.

CD19-positive Relapsed or Refractory B-cell Malignancies

China
AstraZeneca

Recruiting

A Study to Investigate the Effect on Lung Function of an Approved COPD Treatment (BGF, With HFA Propellant) Compared to BGF Formulated With a New Propellant (HFO) in Participants 40 to 80 Years of Age With COPD

COPD (Chronic Obstructive Pulmonary Disease)

United States, Korea, Republic of, Argentina, Turkey, Vietnam, Malaysia, Philippines, Thailand, Hungary, Mexico, Canada, India, Bulgaria, Poland
Sanofi

Recruiting

Real-world Effectiveness Study of Long-term Treatment With Dupilumab in Participants ≥6 Years With Atopic Dermatitis (PROTYPE2)

Atopic Dermatitis

Germany
University Hospital, Grenoble

Not yet recruiting

Continuation of Anti-osteoporotic Treatment 1 Year After Initial Administration (POUROSTEO)

Osteoporosis Fracture
French Innovative Leukemia Organisation
Acute Leukemia French Association

Recruiting

Study Investigating the Efficacy and Safety of the Addition of Oral-azacitidine to Salvage Treatment by Gilteritinib in Subjects ≥18 Years of Age With Relapsed/Refractory FLT3-mutated Acute Myeloid Leukemia (OGILAR)

AML, Adult | Relapsed Adult AML | Refractory AML | FLT3-TKD Mutation | FLT3-ITD

France
Fondation Ophtalmologique Adolphe de Rothschild

Recruiting

Impact of Annual Versus Biannual Infusions of Ocrelizumab in Patients With Active MS,After 2 Years of Initial Treatment, on Freedom From Radiological Disease Activity at Two Years: a Multicenter Randomized Controlled Non-inferiority Trial (WINDOCRE)

Multiple Sclerosis

France
Boehringer Ingelheim
Children's Hospital Acquired Thrombosis consortium

Recruiting

A Study in the United Sates That Looks at the Safety and Effectiveness of Pradaxa Pellets in Children Aged 3 Months to Less Than 12 Years Who Need Treatment of a Blood Clot or Who Have Had a Blood Clot and Are at Risk of Developing Another Blood Clot

Venous Thromboembolism

United States
University of Miami

Recruiting

Treatment of Relapsed/Refractory Intracranial Glioma in Patients Under 22 Years of Age

Glioblastoma Multiforme | Anaplastic Astrocytoma | Oligodendroglioma | Diffuse Intrinsic Pontine Glioma | DIPG Brain Tumor | H3 K27M | Fibrillary Astrocytomas | Diffuse Intrinsic Brainstem Glioma

United States
UNC Lineberger Comprehensive Cancer Center

Recruiting

Long-Term Follow-Up in Women With Early Breast Cancer Three Years of More Post Primary Treatment

Breast Cancer

United States
Ain Shams University

Not yet recruiting

Effect of Lactoferrin Versus Intravenous Iron Sucrose in Treatment of Anemia

Iron Deficiency Anemia
Bayer

Recruiting

A Study to Learn How Gadoquatrane Moves Into, Through, and Out of the Body and How Safe it is in Children (From Birth to <18 Years), Who Will Undergo a Contrast Enhanced MRI (Quanti Pediatric)

Children | Contrast Enhancement in Magnetic Resonance Imaging

United States, Japan, China, Canada, Czechia, Poland, Argentina, Bulgaria, Belgium, Germany, Sweden, Hungary, Italy
Columbia University
Planned Parenthood League of Massachusetts; National Institute on Alcohol Abuse... and other collaborators

Not yet recruiting

Improving Alcohol and Substance Use Care Access, Outcome, Equity During the Reproductive Years

Substance-Related Disorders | Alcohol-Related Disorders | Sexually Transmitted Diseases | Pregnancy | Contraception | Maternal Health | Mental Health | Women's Health | Reproductive Health | Sexual Health

United States
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Exploring the Changes of Inflammatory Factors in Joint Fluid of Patients With Sports Injury for 1-year Postoperative Rehabilitation and Clinical Treatment

Anterior Cruciate Ligament Injuries

China
London School of Hygiene and Tropical Medicine
Radboud University Medical Center; Groupe de Recherche Action en Sante

Recruiting

Understanding and Maximizing the Community Impact of Antimalarial Treatment (INDIE-SMC) (INDIE-SMC)

Malaria | Malaria,Falciparum

Burkina Faso
Protara Therapeutics

Recruiting

Safety and Efficacy Study of Intracystic TARA-002 for the Treatment of Lymphatic Malformations in Participants 6 Months to Less Than 18 Years of Age (STARBORN-1)

Lymphatic Malformation

United States
Massachusetts General Hospital

Recruiting

Repeat BCG Vaccinations for the Treatment of New Onset Type 1 Diabetes in Children Age 8-<18 Years

Diabetes Mellitus | Type 1 Diabetes | Diabetes type1 | Autoimmune Diabetes

United States
Seventh Medical Center of PLA General Hospital
The General Hospital of Central Theater Command; The General Hospital of Northern...

Not yet recruiting

To Evaluate the Clinical Efficacy and Safety of Recombinant Human Interferon ω Spray in Treatment of Viral Upper Respiratory Tract Infection in Children

Viral Upper Respiratory Tract Infection
Second Affiliated Hospital of Soochow University
The Affiliated Hospital of Xuzhou Medical University

Recruiting

Mitoxantrone Hydrochloride Liposome Injection in the Treatment of Relapsed/Refractory Multiple Myeloma

Relapsed/Refractory Multiple Myeloma

China
Institute for Atherosclerosis Research, Russia

Not yet recruiting

The Effects of Allicor on Patients After Revascularization Treatment During a Year (TEA-PARTY)

Peripheral Arterial Disease | Atherosclerosis

Russian Federation
AbbVie

Recruiting

Study to Assess Adverse Events, Change in Disease Activity and How Oral ABBV-552 Capsules Moves Through the Body of Participants Aged 50 to 90 Years With Mild Alzheimer's Disease

Alzheimer's Disease (AD)

United States, Japan, New Zealand, Australia, Spain, Germany, United Kingdom
Vifor Pharma, Inc.

Recruiting

Patiromer for Treatment of Hyperkalaemia in Children Under 12 Years of Age

Hyperkalemia

United States, Israel
AbbVie
Ironwood Pharmaceuticals, Inc.

Recruiting

A Study to Assess Adverse Events and Change in Disease Activity in Pediatric Participants (Age 6 Months to <2 Years) With Functional Constipation Who Are Treated With Linaclotide

Functional Constipation

United States, Bulgaria, United Kingdom, Croatia, Germany, Hungary
European Organisation for Research and Treatment...
Merck KGaA, Darmstadt, Germany

Recruiting

Radiotherapy Plus Xevinapant in Older Patients With Locally Advanced Head and Neck Squamous Cell Carcinoma (RAVINA)

Locally Advanced Head and Neck Squamous Cell Carcinoma

France, Belgium, Netherlands, Norway, United Kingdom, Ireland, Italy, Slovenia, Germany, Spain
Eli Lilly and Company

Recruiting

A Study of Baricitinib (LY3009104) in Children From 6 Years to Less Than 18 Years of Age With Alopecia Areata (BRAVE-AA-PEDS)

Skin Diseases | Pathological Conditions, Anatomical | Alopecia | Hypotrichosis | Hair Diseases | Areata Alopecia

United States, Taiwan, Japan, Spain, Korea, Republic of, Germany, France, Mexico, Canada, Poland, Australia, Hungary, Argentina

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