Search clinical trials for: ZEN-3694

Total 61 results

National Cancer Institute (NCI)

Recruiting

Testing the Safety and Efficacy of the Combination of Two Anti-cancer Drugs, ZEN003694 and Abemaciclib, for Adult and Pediatric Patients (12-17 Years) With Metastatic or Unresectable NUT Carcinoma, Breast Cancer and Other Solid Tumors

Malignant Solid Neoplasm | Breast Carcinoma | NUT Carcinoma

United States
Zenith Epigenetics
Astellas Pharma Inc; Newsoara Biopharma Co., Ltd.

Recruiting

ZEN003694 and Enzalutamide Versus Enzalutamide Monotherapy in Metastatic Castration-Resistant Prostate Cancer

Metastatic Castration-Resistant Prostate Cancer

United States, China
Rahul Aggarwal
Merck Sharp & Dohme LLC; U.S. Army Medical Research and Development Command; Zenith...

Recruiting

ZEN-3694, Enzalutamide, and Pembrolizumab for the Treatment of Metastatic Castration-Resistant Prostate Cancer

Castration-Resistant Prostate Carcinoma | Stage IV Prostate Cancer AJCC v8 | Stage IVA Prostate Cancer AJCC v8 | Stage IVB Prostate Cancer AJCC v8 | Metastatic Prostate Adenocarcinoma | Metastatic Prostate Small Cell Carcinoma

United States
National Cancer Institute (NCI)

Recruiting

Testing the Combination of the Anti-cancer Drugs ZEN003694 (ZEN-3694) and Talazoparib in Patients With Advanced Solid Tumors, The ComBET Trial

Advanced Malignant Solid Neoplasm | Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States
National Cancer Institute (NCI)

Recruiting

Testing A New Anti-cancer Drug Combination, Entinostat and ZEN003694, for Advanced and Refractory Solid Tumors and Lymphomas

Advanced Lymphoma | Advanced Malignant Solid Neoplasm | Advanced Pancreatic Carcinoma | B-Cell Non-Hodgkin Lymphoma | Metastatic Pancreatic Carcinoma | Refractory B-Cell Non-Hodgkin Lymphoma | Refractory Lymphoma | Refractory Malignant Solid Neoplasm | Refractory Pancreatic Carcinoma | Refractory T-Cell... and other conditions

United States
Zenith Epigenetics
Pfizer; Newsoara Biopharma Co., Ltd.

Terminated

A Study of ZEN003694 and Talazoparib in Patients With Triple Negative Breast Cancer (TNBC)

Triple Negative Breast Cancer

United States, Belgium, China, Spain
National Cancer Institute (NCI)

Recruiting

Testing the Combination of the Anticancer Drugs ZEN003694 and Binimetinib in Patients With Advanced/Metastatic or Unresectable Solid Tumors With RAS Alterations and Triple Negative Breast Cancer

Advanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm | Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Triple-Negative Breast Carcinoma

United States
National Cancer Institute (NCI)
NRG Oncology

Recruiting

Testing Different Amounts of the Combination of Drugs M1774 and ZEN-3694 for the Treatment of Recurrent Ovarian and Endometrial Cancer

Ovarian Endometrioid Adenocarcinoma | Endometrial Carcinoma | Endometrial Clear Cell Adenocarcinoma | Endometrial Endometrioid Adenocarcinoma | Ovarian Clear Cell Adenocarcinoma | Ovarian High Grade Serous Adenocarcinoma | Platinum-Resistant Ovarian Carcinoma | Endometrial Low Grade Endometrioid... and other conditions

United States
National Cancer Institute (NCI)

Recruiting

Testing the Addition of an Anti-Cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment (Capecitabine) for Metastatic or Unresectable Cancers

Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Metastatic Colorectal Carcinoma | Stage IV Colorectal Cancer AJCC v8 | Unresectable Colorectal Carcinoma

United States
China Medical University Hospital

Completed

Effect of Su-Man Formula Massage Oil Acupressure on Sleep Quality and Anxiety in Patients With Insomnia

Insomnia

Taiwan
National Cancer Institute (NCI)

Recruiting

Testing the Addition of Anti-cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment, Cetuximab Plus Encorafenib, for Colorectal Cancer

Metastatic Colorectal Adenocarcinoma | Refractory Colorectal Adenocarcinoma | Stage IV Colorectal Cancer AJCC v8

United States
Fourth Affiliated Hospital of Guangxi Medical University
Liuzhou Maternity and Child Healthcare Hospital; Liuzhou Hospital of Traditional...

Unknown

Effectiveness of Acupuncture for Breast Cancer Related Lymphedema (Acupuncture)

Breast Cancer | Lymphedema | Acupuncture
National Cancer Institute (NCI)

Suspended

Testing the Addition of Anti-Cancer Drug, ZEN003694 (ZEN-3694) and PD-1 Inhibitor (Pembrolizumab), to Standard Chemotherapy (Nab-Paclitaxel) Treatment in Patients With Advanced Triple-Negative Breast Cancer

Anatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IV Breast Cancer AJCC v8 | Metastatic Triple-Negative Breast Carcinoma | Unresectable Triple-Negative Breast Carcinoma | Locally Advanced Triple-Negative Breast Carcinoma

United States
Ohio State University

Completed

Urban Zen Integrative Therapy for Persons With Pulmonary Hypertension

Chronic Disease | Pulmonary Hypertension

United States
Laboratoires Arkopharma

Completed

Management of Anxiety in Intensive Care Unit Including Olfactotherapy (OCEAN)

Anxiety

France
National Cancer Institute (NCI)

Recruiting

Testing the Safety and Efficacy of the Addition of A New Anti-cancer Drug, ZEN003694, to Chemotherapy Treatment (Etoposide and Cisplatin) for Adult and Pediatric Patients (12-17 Years) With NUT Carcinoma

Metastatic NUT Carcinoma | Unresectable NUT Carcinoma | Advanced NUT Carcinoma

United States
Zenith Epigenetics

Completed

A Study of ZEN003694 in Combination With Enzalutamide in Patients With Metastatic Castration-Resistant Prostate Cancer

Metastatic Castration-Resistant Prostate Cancer

United States
Zenith Epigenetics

Completed

A Study of ZEN003694 in Patients With Metastatic Castration-Resistant Prostate Cancer

Metastatic Castration-Resistant Prostate Cancer

United States
Chang Gung Memorial Hospital
Ministry of Science and Technology, Taiwan

Recruiting

Development of Three-dimensional Deep Learning for Automatic Design of Skull Implants

Skull Defect

Taiwan
National Cancer Institute (NCI)

Recruiting

Testing the Combination of ZEN003694 and Nivolumab With or Without Ipilimumab in Solid Tumors

Recurrent Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Recurrent Platinum-Resistant Ovarian Carcinoma | Refractory Ovarian Carcinoma

United States
Lykos Therapeutics

Completed

Psychological Effects of Methylenedioxymethamphetamine (MDMA) When Administered to Healthy Volunteers (MT-1)

Psychological Effects of Study Drug

United States
University of Waterloo
Bausch & Lomb Incorporated

Unknown

Corneal Thickness Changes With Scleral Contact Lenses

Keratoconus | Healthy Controls

Canada
Taipei Veterans General Hospital, Taiwan

Recruiting

Machine-learning Algorithm to Differentiate Intraoperative Ketamine Dosing Based on Electroencephalographic Density Spectrum Array Analysis

Ketamine | Electroencephalographic Density Spectrum Array Analysis | Density Spectrum Array | Multimodal General Anesthesia

Taiwan
Hospital Israelita Albert Einstein
Federal University of São Paulo

Completed

The Effects of a Meditation Retreat on Healthy Volunteers and Cancer Patients: an fMRI Study (Sesshin)

Healthy | Cancer

Brazil
Kaohsiung Medical University Chung-Ho Memorial...

Completed

Whole-body Vibration on Mucus Clearance, the Quality of Life, and Exercise Capacity for Patients With Chronic Obstructive Pulmonary Disease

COPD

Taiwan
Hunter College of City University of New York
The City College of New York

Completed

Transcranial Direct Current Stimulation (tDCS) Augments the Effects of Gamified, Mobile Attention Bias Modification

Stress | Anxiety

United States
Da Zen Theranostics Inc

Recruiting

A Pharmacokinetic and Pharmacodynamic Study of DZ-002 in Patients With Advanced Solid Malignancies or Lymphoma

Lymphoma | Solid Tumor

United States
Novo Nordisk A/S

Completed

Observational Study to Observe the Efficacy of Levemir® (Insulin Detemir) in Patients With Type 2 Diabetes.

Diabetes Mellitus, Type 2 | Diabetes

Switzerland
National Taiwan University Hospital

Unknown

A Study Comparing the Supraglottic Airway Devices and Endotracheal Tube During Controlled Ventilation for Laparoscopic Surgery

The Comparison of the I-gel and Endotracheal Tube About in Different Ventilation Settings During Laparoscopic Surgery

Taiwan
Zennea Technologies Inc.
University of Calgary; Interior Health

Completed

Safety, and Tolerability of the ZENS Device (PLUTO)

Snoring | Obstructive Sleep Apnea

Canada
National Taiwan University Hospital

Unknown

The Effects of General Anesthesia on Microcirculation of Central and Peripheral Soft Tissue: a Comparison of Inhalational and Intravenous Anesthetics

Microcirculatory Effects of Anesthesia | Inhalation and Intravenous Anesthesia

Taiwan
RZN Nutraceuticals, Inc.

Unknown

Study of MIGRA-ZEN RELIEF PLUS In the Treatment of Chronic Migraine Headache (RZN)

Chronic Migraine

Israel
Zenith Epigenetics

Withdrawn

Phase 1 Study Evaluating ZEN003365 in Relapsed/Refractory Lymphoproliferative Malignancies or Relapsed/Refractory AML

Acute Myeloid Leukemia | Lymphoproliferative Malignancies

United States
Cancer Institute and Hospital, Chinese Academy...

Recruiting

Real-world Clinical Outcomes of NSCLC Patients Receiving Neoadjuvant Immunotherapy (NeoIM-Lung)

NSCLC

China
National Taiwan University Hospital

Unknown

Interaction Between Nalbuphine and Morphine in PCA

Postoperative Pain

Taiwan
Hospital Miguel Servet

Active, not recruiting

Effectiveness of Four Deconstructive Meditative Practices on Well-being and Self-deconstruction

Mental Health Wellness

Spain
Gian Paolo Fadini
University Hospital Padova

Terminated

Plerixafor in Diabetic Wound Healing (MOZOBL07740)

Diabetes | Critical Limb Ischemia | Wounds

Italy
National Taiwan University Hospital

Recruiting

Methylene Blue Intra-vital Nerve Staining

Neurologic Findings

Taiwan
Alzheimer's Association

Unknown

Couples Coping With Alzheimer's Disease

Dementia | Alzheimer Disease | Aging

United States
Wake Forest University Health Sciences
Alzheimer's Association

Completed

Study of Nasal Insulin to Fight Forgetfulness - Long-acting Insulin Detemir - 120 Days (SL120) (SL120)

Mild Cognitive Impairment | Alzheimer's Disease

United States
Mendel Tuchman
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Unknown

N-Carbamylglutamate (Carbaglu) In The Treatment Of Hyperammonemia

Inborn Errors of Metabolism

United States
Zhenhua Zen

Completed

Hypertension in Patients Hospitalized With COVID-19 (HT-COVID19)

COVID-19 | Hypertension

China
Zhenhua Zen

Completed

Acute Kidney Injury in Patients Hospitalized With COVID-19

COVID-19 | Acute Kidney Injury | Kidney Function

China
isRed Pharma & Biotech Research Corporation
Yung Shin Pharmaceutical Ind. Co., Ltd.

Unknown

A Pharmacokinetic Study to Evaluate the Bioequivalence of a Test Formulation Compared to an Equivalent Dose of a Reference Drug Product

Healthy Adult Subjects

Taiwan
Lykos Therapeutics

Completed

Open Label Multi-Site Study of Safety and Effects of MDMA-assisted Therapy for Treatment of PTSD

PTSD

United States
Lykos Therapeutics

Completed

A Multi-Site Open-Label Extension Study of MDMA-Assisted Psychotherapy for PTSD (MAPPUSX)

PTSD

United States, Canada, Israel
University Hospital, Caen

Completed

Impact of Sophrology on the Pain Felt During a Bone Marrow Aspiration and Biopsy (BOM-ZEN)

Pain | Hematologic Diseases | Diagnoses Disease

France
Asklepieion Voulas General Hospital
Aretaieion University Hospital

Completed

The Effect of Tramadol on Interscalene Brachial Plexus Block

Rotator Cuff Injury | Shoulder Arthritis | Shoulder Dislocation | Shoulder Fracture

Greece
Lykos Therapeutics

Completed

A Multi-Site Phase 3 Study of MDMA-Assisted Psychotherapy for PTSD (MAPP2)

Posttraumatic Stress Disorder

United States, Israel
Lykos Therapeutics

Completed

A Multi-Site Phase 3 Study of MDMA-Assisted Psychotherapy for PTSD (MAPP1)

Posttraumatic Stress Disorder

United States, Israel, Canada

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