Search clinical trials for: antibiotic monotherapy

Total 9953 results

Centre Hospitalier Intercommunal Creteil
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Comparison of Two Antibiotic Regimens for the Treatment of Early Airways Infection With PA in Adults With Bronchiectasis (ANTEIPA)

Bronchiectasis

France
Leiden University Medical Center
Radboud University Medical Center; University Medical Center Groningen; Erasmus... and other collaborators

Recruiting

Rifampicin Combination Therapy Versus Monotherapy for Staphylococcal Prosthetic Joint Infection (RiCOTTA)

Prosthetic-joint Infection | Infection Hip | Infection; Knee, Joint

Netherlands
Rambam Health Care Campus
Fondazione Policlinico Universitario Agostino Gemelli IRCCS; Imperial College... and other collaborators

Recruiting

Lyophilized Fecal Microbiome Transfer vs. Vancomycin Monotherapy for Primary Clostridioides Difficile Infection (DONATE)

Clostridioides Difficile Infection

Israel, Canada, Hungary, Italy, Lithuania, United Kingdom
University of Southern Denmark
Hospital of South West Jutland

Not yet recruiting

Comparison of Three Different Antibiotic Treatments Against Recurrent Urinary Tract Infections in Catheterized Patients

Recurrent Urinary Tract Infections | Antibiotic Treatment | Chronic Urinary-catheter-carrier | Biofilm Infection | Replacement of Urinary Catheter
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Recruiting

A Study of SKLB1028 Versus Salvage Chemotherapy in Patients With Relapsed or Refractory (R/R) AML With FLT3-Mutated (ALIVE)

Acute Myeloid Leukemia (AML)

China
Academisch Medisch Centrum - Universiteit van Amsterdam...
Bristol-Myers Squibb

Recruiting

A Study of Mitomycin-c/ Capecitabine ChemoRadiotherapy Combined With Nivolumab Monotherapy or Ipilumimab and Nivolumab, as Bladder Sparing Curative Treatment for Muscle Invasive Bladder Cancer: the CRIMI Study (CRIMI)

Urinary Bladder Cancer | Invasive Bladder Cancer

Netherlands
Genmab
AbbVie

Active, not recruiting

Trial of the Safety and Efficacy of Epcoritamab in Japanese Subjects With R/R B-NHL (EPCORE™ NHL-3)

Follicular Lymphoma | Marginal Zone Lymphoma | Diffuse Large B Cell Lymphoma | Small Lymphocytic Lymphoma | High-grade B-cell Lymphoma | Primary Mediastinal Large B Cell Lymphoma

Japan
Genmab
AbbVie

Active, not recruiting

A Study to Evaluate Adverse Events and Change in Disease Activity of Subcutaneous (SC) Epcoritamab As Monotherapy or Combined With Standard of Care Therapies in Adult Participants in China With B-Cell Non-Hodgkin Lymphoma

B-Cell Non-Hodgkin Lymphoma

China
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Donor Peripheral Stem Cell Transplant in Treating Patients With Advanced Hematologic Cancer or Other Disorders

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Diseases | Graft Versus Host Disease | Precancerous/Nonmalignant Condition
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Auto BMT for Non-M3 AML in 1st Remission in Pts </=60y of Age Using Busulfan/FTBI & VP16 as a Prep R

Leukemia
Novartis Pharmaceuticals

Completed

Study to Assess the Safety and Efficacy of Midostaurin (PKC412) in Combination With Standard Chemotherapy During Induction and Consolidation Followed by 12 Months of Maintenance Monotherapy in Patients With Newly-diagnosed FMS-like Tyrosine 3 (FLT3) Kinase Receptor-mutated Acute Myeloid Leukemia.

Acute Myeloid Leukemia

Italy, Croatia, Estonia, Czechia, France, Spain, Sweden, Bulgaria, Lithuania, Serbia, Hungary, Finland, Norway, Romania, Slovakia
Chulalongkorn University

Completed

Single Versus Combined Antibiotic Therapy for Bacterial Peritonitis in CAPD Patients

Peritonitis

Thailand
Massachusetts General Hospital
Transplant Genomics, Inc.; CareDx

Completed

Immune Monitoring to Facilitate Belatacept Monotherapy

Kidney Transplant Rejection | Immunosuppression

United States
Haiphong University of Medicine and Pharmacy

Completed

Combination Antibiotic Therapy Compared to Monotherapy in the Treatment of Acute COPD (COPD)

COPD Exacerbation Acute

Vietnam
Piemonti Lorenzo
Italian Diabetes Foundation

Completed

Monotherapy With Rapamycin in Long-standing Type 1 Diabetes (MONORAPA)

Diabetes Mellitus, Type 1

Italy
Gilead Sciences

Terminated

Entospletinib (ENTO) as Monotherapy and in Combination With Chemotherapy in Japanese Adults (Japanese AML)

Acute Myeloid Leukemia | Hematologic Malignancy

Japan
SCARE (Study group for carbapenem resistance)

Unknown

Comparison of Bloodstream Infections With Carbapenem Hetero-resistant vs Carbapenem Resistant Klebsiella Pneumoniae (COMBAT)

Bloodstream Infection

Turkey
Gilead Sciences

Terminated

Entospletinib Monotherapy and in Combination With Chemotherapy in Adults With Acute Myeloid Leukemia (AML) (ENTO in AML)

Acute Myeloid Leukemia

United States, Canada, Germany
University of Wisconsin, Madison

Terminated

Mycophenolic Acid Monotherapy in Recipients of HLA-identical Living-Related Transplantation

Kidney Transplantation

United States
Gangnam Severance Hospital

Completed

Colistin-rifampin Combination and Colistin Monotherapy in Extensively Drug-resistant Acinetobacter Baumannii

Acinetobacter Infections | Colistin | Rifampin
National Cancer Institute (NCI)

Completed

Pilot Study of Liposomal Doxorubicin Combined With Bevacizumab Followed by Bevacizumab Monotherapy in Adults With Advanced Kaposi s Sarcoma

Sarcoma, Kaposi

United States
Sanofi
Regeneron Pharmaceuticals

Completed

A Study Assessing the Safety and Efficacy of Sarilumab Added to Non-MTX DMARDs or as Monotherapy in Japanese Patients With Active Rheumatoid Arthritis (SARIL-RA-HARUKA)

Rheumatoid Arthritis

Japan
Assistance Publique - Hôpitaux de Paris
Novartis

Completed

Evaluation of Low Dose Corticosteroids Efficiency, Associated With Myfortic ® in the Treatment of Nephrotic Syndrome (MSN)

Nephrotic Syndrome

France
Merck Sharp & Dohme LLC

Terminated

Pegylated Liposomal Doxorubicin (Caelyx(R)) as Monotherapy in Elderly Patients With Locally Advanced and/or Metastatic Breast Cancer (Study P05059)

Breast Neoplasms
Merrimack Pharmaceuticals

Unknown

Safety and Pharmacokinetic Study of MM-302 in Patients With Advanced Breast Cancer

Breast Cancer

United States
Northwestern University
Roche Pharma AG

Terminated

A Trial of Two Steroid-Free Approaches Toward Mycophenolate Mofetil-Based Monotherapy Immunosuppression (Cell220)

Kidney Transplant Failure and Rejection

United States
Janssen Research & Development, LLC

Completed

Study of DOXIL/CAELYX (Pegylated Liposomal Doxorubicin) and VELCADE (Bortezomib) or VELCADE Monotherapy for the Treatment of Relapsed Multiple Myeloma

Multiple Myeloma

Australia, France, Poland, United Kingdom, United States, Spain, Israel, Portugal, South Africa, Canada, Netherlands, Belgium, Singapore, Russian Federation, Czech Republic, Argentina, Austria
Northwestern University
Northwestern Memorial Hospital

Completed

Immune Tolerance and Alloreactivity in Liver Transplant Recipients on Different Monotherapy Immunosuppressive Agents

Immunosuppression | Liver Transplant Rejection

United States
National Cancer Institute (NCI)

Terminated

SGN-30 and Combination Chemotherapy in Treating Patients With Newly Diagnosed Anaplastic Large Cell Lymphoma

Anaplastic Large Cell Lymphoma

United States
University of Wisconsin, Madison
Novartis Pharmaceuticals

Terminated

Mycophenolic Acid (MPA) Monotherapy in Liver Transplantation

Liver Transplant

United States
Johnson & Johnson Pharmaceutical Research & Development...

Completed

A Study of Docetaxel Monotherapy or DOXIL and Docetaxel in Patients With Advanced Breast Cancer

Breast Cancer

United States, Poland, Ukraine, United Kingdom, Spain, Israel, Bulgaria, Romania, Serbia, South Africa, Russian Federation, Hungary, Lithuania, Netherlands, Latvia, Portugal, Estonia, France
GlaxoSmithKline
NSABP Foundation Inc

Completed

Treatment With Pazopanib for Neoadjuvant Breast Cancer

Neoplasms, Breast

United States, Canada
Oslo University Hospital

Unknown

Rifampin Combination Therapy Versus Monotherapy in Early Staphylococcal Infections After Total Hip and Knee Arthroplasty

Staphylococcal Infections | Prosthesis-related Infections

Norway
Shi-Ming Lin

Unknown

Combine TACE and RFA Versus RFA Monotherapy in Unilobar HCC of 3.1 to 7 cm Patient

Hepatocellular Carcinoma

Taiwan
Swiss National Fund for Scientific Research
University Hospital, Geneva

Completed

Monotherapy Versus Bitherapy in Non-severe Hospitalized Community-acquired Pneumonia (BICAP)

Community-acquired Pneumonia

Switzerland
Poitiers University Hospital

Completed

Maintenance Neoral Monotherapy Compared to Bitherapy in Renal Transplantation

Kidney Transplantation

France
Merck Sharp & Dohme LLC
GOG Foundation; European Network of Gynaecological Oncological Trial Groups...

Not yet recruiting

A Study to Compare Sacituzumab Tirumotecan (MK-2870) Monotherapy Versus Treatment of Physician's Choice as Second-line Treatment for Participants With Recurrent or Metastatic Cervical Cancer (MK-2870-020/TroFuse-020/Gog-3101/ENGOT-cx20)

Cervical Cancer
Merck Sharp & Dohme LLC

Not yet recruiting

A Study of MK-6837 as a Monotherapy and Combination Therapy in Participants With Advanced/Metastatic Solid Tumors (MK-6837-001)

Neoplasm Metastasis
Children's Hospital of Philadelphia
Eli Lilly and Company; United States Department of Defense

Not yet recruiting

Selpercatinib Pre-RAI in Patients With RET Fusion Thyroid Cancer (RAISE) (RAISE)

Cancer | Pediatric Cancer | Differentiated Thyroid Cancer | Cancer, Thyroid
SK Life Science, Inc.

Not yet recruiting

Open-label Study of Cenobamate Monotherapy in Adult Subjects With Newly Diagnosed or Recurrent Partial-Onset Epilepsy

Focal Onset Seizure
Biocodex

Not yet recruiting

Effect of Saccharomyces Boulardii CNCM I-745 on Gut Microbiota in Patients Undergoing Antibiotic Therapy (in the Context of Erythema Migrans (Early Skin Form of Lyme Borreliosis)) (SUBLYME)

Erythema Migrans of Lyme Disease
Guangdong Provincial People's Hospital

Not yet recruiting

Randomized Study of ABC-14 Regimen Compared With "3+7" Standard Induction Therapy or AB-14 for ND AML

Acute Myeloid Leukemia

China
South Valley University
Assiut University

Not yet recruiting

Egyptian Arthroplasty Surgeons' Antibiotics Usage Awareness

Infections Joint Prosthetic

Egypt
Eye & ENT Hospital of Fudan University
Soochow University

Recruiting

Novel Antisense Oligonucleotide Eye Drops for Treating Antibiotic-Resistant Bacterial Keratitis (ASOTARI)

Eye Diseases | Corneal Diseases | Sensation Disorders | Vision Disorders | Blindness | Infections, Bacterial | Bacterial Keratitis | Antibiotic-resistant Bacteria | Antisense Peptide Nucleic Acid | Antibacterial Therapy

China
Universitas Diponegoro
Dr. Kariadi General Hospital Medical Center

Recruiting

Biomarkers & Infection After Prophylactic Antibiotic in Cardiac Implantable Electronic Device Implantation (BI-PACED)

Heart Block | Biomarkers | Antibiotic Prophylaxis | CIED Related Infection | CIED-related Infections

Indonesia
Takeda

Not yet recruiting

A Study to Learn About the Safety of Vedolizumab and How Well it Works in Children and Teenagers With Active Chronic Pouchitis

Pouchitis

Belgium, Spain, Czechia, Italy, Israel, Croatia, Greece, Poland
Sanofi

Not yet recruiting

A Study to Evaluate the Efficacy and Safety of Subcutaneous Amlitelimab Monotherapy Compared With Placebo in Adult Participants With Severe Alopecia Areata

Alopecia Areata
Ruijin Hospital

Not yet recruiting

Efficacy of Pola-RCHP-X vs Pola-RCHP in Untreated DLBCL

Diffuse Large B-Cell Lymphoma
Penn State University

Not yet recruiting

Optimizing Antibiotics Prescription: A Stepped-Wedge Randomized Trial

Antimicrobial Resistance
Faming Zhang

Not yet recruiting

Effect of Antibiotic Pretreatment on the Efficacy of WMT in the Treatment of Irritable Bowel Syndrome

Irritable Bowel Syndrome

China

Search clinical trials for: antibiotic monotherapy

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