Search clinical trials for: beta lactam

Total 8607 results

University Hospital, Ghent

Recruiting

Pediatric Antibiotic Dosing in Extracorporal Membrane Oxygenation (PADECMO) (PADECMO)

Pharmacokinetics | Vancomycin | Amoxicillin-clavulanate | Piperacillin-tazobactam | Teicoplanin | Meropenem | Ciprofloxacin | Amikacin | Cefazolin

Belgium
Instituto Nacional de Cancerologia de Mexico

Recruiting

Ceftolozane/Tazobactam vs. Piperacillin/Tazobactam for the Treatment of Bacteremia in Hemato-oncological Patients

Hematologic Neoplasms | Neutropenia

Mexico
Hospital Italiano de Buenos Aires

Not yet recruiting

Mortality of MBL-producing Enterobacteriaceae Bacteremias With the Combined Use of Ceftazidime-avibactam and Aztreonam vs. Other Active Antibiotics. A Multicenter Target Trial Emulation.

Bacteremia
Massachusetts General Hospital
National Institute of Allergy and Infectious Diseases (NIAID)

Not yet recruiting

Optimizing the Diagnostic Approach to Cephalosporin Allergy Testing (DACAT)

Drug Hypersensitivity | Drug-Induced Anaphylaxis | Antibiotic Allergy | Drug Allergy | Beta Lactam Adverse Reaction | Cephalosporin Allergy | Cephalosporin Reaction

United States
Ohio State University

Not yet recruiting

Improvement of PPROM Management With Prophylactic Antimicrobial Therapy (iPROMPT)

Preterm Birth | Pregnancy, High Risk | Preterm Premature Rupture of Membrane

United States
Assistance Publique Hopitaux De Marseille

Not yet recruiting

Screen-and-treat Strategy for Vaginal Flora Abnormalities in Pregnant Women at High Risk of Preterm Birth (AUTOP2)

Bacterial Vaginosis | Premature Delivery | Vaginal Dysbiosis
Beneficência Portuguesa de São Paulo
Merck Sharp & Dohme LLC

Not yet recruiting

Ceftolozane/Tazobactam Versus Meropenem for Febrile Neutropenia on Patients Colonized With or at Risk for Infection With Extended Spectrum Beta Lactamase - Producing Pathogens (CLEMENT)

Febrile Neutropenia

Brazil
University Hospital, Grenoble

Not yet recruiting

Pharmacokinetics and Modelling of Beta-Lactam in ECMO-VA Patients (KAMELOT)

Infections | Cardiac Arrest | Cardiogenic Shock | Extracorporeal Membrane Oxygenation Complication | Post-cardiac Surgery

France
Clinical Research Centre, Malaysia

Not yet recruiting

Early Intravenous to Oral Antibiotic Switch in Uncomplicated Staphylococcus Aureus Bacteraemia (EVOS)

Staphylococcus Aureus Bacteremia

Malaysia
Petrovsky National Research Centre of Surgery

Recruiting

Antibacterial Tactics Based on Presepsin Level in Thoracic Aorta Surgery Patients

Thoracic Aortic Aneurysm | Thoracic Aortic Dissection | Cardiac Valve Disease | Aortic Aneurysm and Dissection

Russian Federation
Centre Hospitalier Universitaire Vaudois
Unisanté Centre universitaire de médecine générale et santé publique; FORCE...

Not yet recruiting

Adjustment of Antibiotic Dosage in Pediatric Oncology Patients With Febrile Neutropenia and Augmented Renal Clearance (DAR-ARC)

Febrile Neutropenia

Switzerland
Hellenic Institute for the Study of Sepsis

Recruiting

Clarithromycin Treatment to Prevent Sepsis Progression in CAP (REACT) (REACT)

Community-acquired Pneumonia

Greece
The Methodist Hospital Research Institute
M.D. Anderson Cancer Center; National Institute of Allergy and Infectious Diseases... and other collaborators

Recruiting

Dynamics of Colonization and Infection by Multidrug-Resistant Pathogens in Immunocompromised and Critically Ill Patients (DYNAMITE)

Antibiotic Resistant Infection | Clostridium Difficile | Antimicrobial Drug Resistance | Carbapenem-Resistant Enterobacteriaceae Infection | Vancomycin Resistant Enterococci Infection | Vancomycin-Resistant Enterococcal Infection | Carbapenem Resistant Bacterial Infection | Extended Spectrum Beta-Lactamase...

United States
Otto Helve
University of Helsinki

Not yet recruiting

Autoflor -Lyophilized Capsulated Autological FMT to Restore Gut Microbiome After Treatment With Antibiotics (FMT)

Microbial Colonization | Antibiotic Side Effect

Finland
Nantes University Hospital

Not yet recruiting

Amoxicillin Alone Versus Amoxicillin/Clavulanate for Community-acquired Pneumonia in Patients Aged 65 Years or Older, and Hospitalized in a Non-intensive Care Unit Ward (CAPTAIN)

Community-acquired Pneumonia
Sichuan Provincial People's Hospital

Not yet recruiting

Precise Treatment of Ceftazidime-Avibactam in Patients With CRO Infections Under the Guidance of TDM and PPK Model

ECMO | Carbapenem-Resistant Enterobacteriaceae Infection
University Hospital, Strasbourg, France

Recruiting

Interest in Probabilistic Antibiotic Therapy With Broad-spectrum Beta-lactams in Orthopedic Surgery (Prob-ATB)

Joint Infection

France
Assiut University

Not yet recruiting

Prophylactic Antibiotic in Non-complicated Low Risk Lap Cholecystectomy (LC)

Cholecystectomy, Laparoscopic
Scandinavian Critical Care Trials Group

Not yet recruiting

Empirical Meropenem Versus Piperacillin/Tazobactam for Adult Patients With Sepsis (EMPRESS)

Sepsis | Septic Shock

Denmark
Qpex Biopharma, Inc.
Shionogi Inc.; Biomedical Advanced Research and Development Authority

Not yet recruiting

PK & Safety Study of Xeruborbactam Oral Prodrug Combined With Ceftibuten in Participants With Renal Impairment

Bacterial Infections
University Hospital, Rouen

Not yet recruiting

Postoperative Anti-infective Strategy Following Pancreaticoduodenectomy in Patients With Preoperative Biliary Stent (FRENCH24 ANIS)

Pancreaticoduodenectomy | Antibiotherapy
Shionogi

Recruiting

A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Cefiderocol in Hospitalized Neonates and Infants

Gram-Negative Bacterial Infections

United States, South Africa, Taiwan
Qpex Biopharma, Inc.
Shionogi Inc.; Biomedical Advanced Research and Development Authority

Recruiting

P1, DDI & MAD PK and Safety Study of Xeruborbactam Oral Prodrug in Combo With Ceftibuten in Healthy Participants

Bacterial Infections

Australia
Shandong University
Shandong Provincial Hospital

Recruiting

Population Pharmacokinetic of Piperacillin/Tazobactam in Maternal and Neonatal Populations

Early-Onset Neonatal Sepsis

China
Suzhou Erye Pharmaceutical Co., Ltd.

Recruiting

Study of the Safety, Tolerability, and PK of SZEY-2108 Administered Intravenously to HVs in SAD and MAD Cohorts

Infections

China
Sunshine Coast Hospital and Health Service
The Prince Charles Hospital; Mater

Not yet recruiting

Ceftolozane/Tazobactam Continuous Infusion for Infective Exacerbations of Cystic Fibrosis and Bronchiectasis (CERTAIN)

Bronchiectasis | Cystic Fibrosis | Pseudomonas Aeruginosa | Burkholderia Cepacia Infection
University Hospital, Ghent
Imec; Research Foundation Flanders

Not yet recruiting

Validation of Betalactam ML Prediction Models - TDMAide (TDMAide)

Infections

Belgium
Helse Stavanger HF
Oslo University Hospital; Haukeland University Hospital; St. Olavs Hospital; Alesund... and other collaborators

Recruiting

Antibiotics, Microbiology and Immunology in Children With Chronic Wet Cough - the AMIC Study (AMIC)

Protracted Bacterial Bronchitis

Norway
Shandong University
Shandong Provincial Hospital; Qianfoshan Hospital; Jining Medical University; Yantai... and other collaborators

Recruiting

Model-based Dose Versus Empirical Dose of Piperacillin/Tazobactam in Preterm Neonates With Late-onset Sepsis. (PIP/TAZO)

Late-Onset Neonatal Sepsis

China
McMaster Children's Hospital

Not yet recruiting

Piperacillin/Tazobactam Versus ceftriAxone and Metronidazole for Children With Perforated Appendicitis (ALPACA) (ALPACA)

Appendicitis Perforated
Singapore General Hospital

Recruiting

Therapeutic Drug Monitoring in Patients With Difficult-to-Treat Gram-Negative Bacterial Infections (TDM-RCT)

Sepsis | Bacterial Infections | Therapeutic Drug Monitoring | Hemodynamic Instability | Antimicrobial Resistance

Singapore
Biruni University

Not yet recruiting

Effects of Antibiotic Prophylaxis on the Healing Parameters Following Surgical Crown Lengthening (SCLABP)

Tooth Diseases | Tooth Wear
Rambam Health Care Campus
Assaf-Harofeh Medical Center; Sheba Medical Center; Monaldi Hospital; Rutgers Robert... and other collaborators

Not yet recruiting

Cefiderocol and Ampicillin-sulbactam vs. Colistin +/- Meropenem for Carbapenem Resistant A. Baumannii (CASCADE)

Carbapenem Resistant Bacterial Infection | Acinetobacter Bacteremia | Acinetobacter Pneumonia
Sunnybrook Health Sciences Centre
Canadian Institutes of Health Research (CIHR)

Recruiting

BALANCE+ Vanguard Phase (BALANCE+)

Gram-negative Bacteremia

Canada
University of Louisville
Osteo Science Foundation

Not yet recruiting

Efficacy of Oral vs IV Antibiotics in the Treatment of Orofacial Osteomyelitis

Osteomyelitis of Jaw

United States
Phramongkutklao College of Medicine and Hospital
Silpakorn University

Recruiting

Dose Optimization by Pharmacokinetic/Pharmacodynamic of Antibiotics to Improve Clinical Outcome of Carbapenem Resistant Klebsiella Pneumoniae Bloodstream Infections in Critically Ill Patients at Phramongkutklao Hospital

Carbapenem Resistant Klebsiella Pneumoniae

Thailand
Qianfoshan Hospital

Recruiting

Drug Resistance Mechanism of Enterobacteriaceae and Its Strategies

Carbapenem-Resistant Enterobacteriaceae Infection

China
University of Missouri-Columbia

Recruiting

CAT BITE Antibiotic Prophylaxis for the Hand/Forearm (CATBITE) (CATBITE)

Infection, Bacterial | Anti-bacterial Agents | Hand Injuries | Arm Injury | Cat Bite

United States
Emory University
Centers for Disease Control and Prevention

Recruiting

Further MT for AntIbiotic-Resistant Bacterial Colonization in Inpatients (FAIR)

Multi-drug Resistant Organism

United States
Hanna Jangö
Region Hovedstadens Apotek

Recruiting

Oral Antibiotics After Obstetric Perineal Tear (REPAIR)

Infections | Wound Dehiscence | Obstetric Trauma

Denmark
Allecra
Linical Co., Ltd.

Recruiting

A Study to Investigate PK, Safety, Tolerability of Cefepime-enmetazobactam in Pediatric Participants With cUTI

Complicated Urinary Tract Infection

Spain, France, Czechia, Hungary, Poland, Slovakia
Anabio R&D
Thai Binh University of Medicine and Pharmacy

Recruiting

LiveSpo Navax® Supports the Treatment of Acute Rhinosinusitis and Otitis Media

Upper Respiratory Tract Infections

Vietnam
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Household Transmission Dynamics of Multidrug Resistant Enterobacterales (HOME)

Adults Patients, With Fecal Carriage of Multi-Drug Resistant Enterobacterales (MDR-E)
Fundació Institut de Recerca de l'Hospital de la...

Recruiting

Fast Track Therapeutic Model in Acute Complicated Appendicitis in Pediatrics (FTAA)

Complicated Appendicitis | Laparoscopic Appendectomy | Periappendicular Abscess

Spain
Case Comprehensive Cancer Center

Recruiting

eXtended Antibiotic Prophylaxis for Intermediate- and High-risk Glands After Pancreatoduodenectomy to Reduce CR-POPF

Pancreatic Fistula

United States
Assistance Publique - Hôpitaux de Paris

Recruiting

Beta-lactam Intermittent Versus Continuous Infusion and Combination Antibiotic Therapy in Sepsis (BICCS)

Sepsis

France
Monash University

Recruiting

Role of Antibiotic Therapy or Immunoglobulin On iNfections in hAematoLogy: Immunoglobulin Stopping or Extension (RATIONALISE)

Hypogammaglobulinemia | Haematological Malignancy

Australia
Western Sydney Local Health District
Centre Of Research Excellence in Tuberculosis Control

Recruiting

The BLAST- 1 Trial - Cephalexin+Amoxicillin-clavulanate for Tuberculosis (BLAST)

Tuberculosis, Pulmonary

Australia
Pfizer

Recruiting

Study of 2 Medicines (Aztreonam and Avibactam) Compared to Best Available Therapy for Serious Gram-negative Infections

Gram-negative Bacterial Infections

Spain, Taiwan, United States, Hungary, India, China, Turkey, Greece, Czechia
Kaizen Bioscience Co.

Recruiting

A Pharmacokinetic Study of LP-001 in Children With a Bacterial Infection

Bacterial Infections | Pediatric

United States

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