Search clinical trials for: caspofungin

Total 80 results

Fujian Shengdi Pharmaceutical Co., Ltd.

Not yet recruiting

A Trial of Intravenous HRS9432 in the Treatment of Subjects With Candidemia and/or Invasive Candidiasis

Patients With Candidemia and/or Invasive Candidiasis
Basilea Pharmaceutica

Not yet recruiting

A Phase 3 Efficacy and Safety Study of Fosmanogepix for the Treatment of Adult Participants With Candidemia and/or Invasive Candidiasis

Candidemia | Candidiasis, Invasive
Children's Hospital of Fudan University

Not yet recruiting

PK/PD of Caspofungin in Children Severe Infection

Pharmacokinetics | Infection, Fungal

China
Shanghai General Hospital, Shanghai Jiao Tong University...

Not yet recruiting

To Evaluate the Efficacy and Safety of Micafungin in Preventing Invasive Mycosis After Liver Transplantation

Liver Transplantation
Cidara Therapeutics Inc.

Recruiting

Study of Rezafungin Compared to Standard Antimicrobial Regimen for Prevention of Invasive Fungal Diseases in Adults Undergoing Allogeneic Blood and Marrow Transplantation (ReSPECT)

Mycoses | Candidemia | Fungemia | Fungal Infection | Invasive Candidiasis | Invasive Fungal Disease | Pneumocystis | Mold Infection | Prophylaxis of Invasive Fungal Infections | Aspergillus

United States, Germany, France, Belgium, Canada, Italy, Spain, United Kingdom, Turkey, Switzerland
Centre Hospitalier Universitaire, Amiens

Recruiting

Study Comparing Caspofungin to Placebo for the Treatment of ICU Intra-abdominal Candidiasis (CASPER)

ICU Yeast Intra-abdominal Infection

France
European Organisation for Research and Treatment...

Completed

Empirical Versus Preemptive Antifungal Therapy

Myelodysplastic Syndromes | Leukemia | Fungal Infection

Belgium, Netherlands, Germany, France, Czechia, Slovakia
Scynexis, Inc.

Suspended

A Phase 3, Randomized, Double-blind Study for Patients With Invasive Candidiasis Treated With IV Echinocandin Followed by Either Oral Ibrexafungerp or Oral Fluconazole (MARIO)

Candidemia | Candidiasis, Invasive

United States, Korea, Republic of, Greece, Canada, France, Belgium, Germany, Italy, Spain, South Africa, Bulgaria, Israel
LI YAN

Completed

Effect of Azole/Echinocandin Use on Tacrolimus Pharmacokinetics

Kidney Transplant Patients

China
Shandong University

Completed

Population Pharmacokinetics and Dose Optimization of Caspofungin in Adolescents

Invasive Fungal Infections

China
Universitair Ziekenhuis Brussel

Completed

Initiation of Ovarian Stimulation With Recombinant-human FSH (Bemfola®) in the Late Follicular Phase

Infertility, Female

Belgium
Cidara Therapeutics Inc.

Completed

Study of Rezafungin Compared to Caspofungin in Subjects With Candidemia and/or Invasive Candidiasis (ReSTORE)

Mycoses | Candidemia | Fungal Infection | Invasive Candidiases

United States, Israel, Spain, Korea, Republic of, Taiwan, Singapore, Thailand, Australia, China, Turkey, Belgium, Germany, France, Argentina, Bulgaria, Colombia, Greece, Italy
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Caspofungin Acetate, Fluconazole, or Voriconazole in Preventing Fungal Infections in Patients Following Donor Stem Cell Transplant

Hematopoietic and Lymphoid Cell Neoplasm | Fungal Infection

United States, Canada
Cttq

Completed

Empiric Therapy of Patients With Persistent Fever and Agranulocytosis Using Caspofungin

Fungal Infection

China
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Caspofungin Versus Fluconazole in Preventing Invasive Fungal Infections (IFI) in Patients Undergoing Chemotherapy for Acute Myeloid Leukemia

Acute Myeloid Leukemia | Recurrent Adult Acute Myeloid Leukemia | Fungal Infection | Neutropenia | Secondary Acute Myeloid Leukemia | Untreated Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia in Remission | Childhood Acute Myeloid Leukemia in Remission | Recurrent Childhood Acute Myeloid... and other conditions

United States, Canada, Puerto Rico
Cidara Therapeutics Inc.

Completed

CD101 Compared to Caspofungin Followed by Oral Step Down in Subjects With Candidemia and/or Invasive Candidiasis-Bridging Extension (STRIVE)

Mycoses | Candidemia | Fungemia | Fungal Infection | Invasive Candidiasis

United States, Spain, Belgium, Russian Federation, Greece, Bulgaria, Canada, Hungary, Italy, Romania
Radboud University Medical Center

Completed

Pharmacokinetics of Caspofungin (Cancidas ®) Given Intravenously as Therapy to Patients With an Invasive Fungal Infection in the Intensive Care Unit - a Search for Co-variates (CASCADE)

Invasive Fungal Infection

Netherlands
Hospices Civils de Lyon

Completed

Therapeutic Drug Monitoring of Antifungals in Intensive Care Units (Fungi-up)

Intensive Care Unit Patients

France
Beijing Chao Yang Hospital

Unknown

Effects and Safety of Caspofungin and Corticosteroids in Pneumocystis Pneumonia in Non-HIV Patients

Pneumocystis Pneumonia

China
Merck Sharp & Dohme LLC

Terminated

Safety, Tolerability, and Efficacy of Caspofungin Versus Amphotericin B Deoxycholate in the Treatment of Invasive Candidiasis in Neonates and Infants (MK-0991-064)

Candidiasis, Invasive
Bin Du

Unknown

Trimethoprim/Sulfamethoxazole Combined With Caspofungin as First-line Therapy in PCP

Pneumocystis Pneumonia

China
Universitaire Ziekenhuizen KU Leuven
KU Leuven

Unknown

Impact of Capillary Leak and Hypoalbuminemia on PK/PD of Anidulafungin and Caspofungin in Critically Ill Patients

Critically Ill Patients

Belgium
Centre Hospitalier Universitaire de Saint Etienne
Merck Sharp & Dohme LLC

Completed

Evaluation of the Pharmacokinetics of Caspofungin in ICU Patients (CaspoKin)

Shock

France
Astellas Pharma Europe B.V.
World Health Information Science Consultants, LLC

Completed

Short and Long-term Safety of Micafungin and Other Parenteral Antifungal Agents (MYCOS)

Systemic Fungal Infections

United States
Xian-Janssen Pharmaceutical Ltd.

Terminated

A Study Comparing the Efficacy of Intravenous Followed by Oral Itraconazole With Intravenous Caspofungin For Empiric Antifungal Therapy in Neutropenic Participants With Hematological Malignancy

Hematologic Neoplasms

China
Astellas Pharma Inc

Completed

Liver Transplant European Study Into the Prevention of Fungal Infection (TENPIN)

Liver Transplantation | Mycoses

Belgium, France, Italy, Spain, Ireland, Germany, Portugal, Saudi Arabia, Austria, United Kingdom, Russian Federation, Hungary, Sweden, Romania
Erasme University Hospital

Completed

Pharmacokinetics of Caspofungin After One Dose in Patients With Liver Failure

Bacterial Infections and Mycoses | Liver Disease

Belgium
Astellas Pharma Inc
Basilea Pharmaceutica

Completed

Isavuconazole (BAL8557) in the Treatment of Candidemia and Other Invasive Candida Infections

Mycoses | Candidemia | Candidiasis, Invasive

Philippines, New Zealand, United States, Spain, Belgium, Canada, Israel, Malaysia, Mexico, Italy, Australia, Germany, Singapore, Hungary, Brazil, Thailand, China, India, Argentina, France, Russian Federation, Chile, Lebanon, South Africa and more
Centre Hospitalier Universitaire de Nīmes

Completed

Pharmacokinetic Study on Echinocandins for Patients With Septic Shock Following Secondary Peritonitis

Septic Shock | Peritonitis

France, Australia
Careggi Hospital

Completed

Pharmacokinetics/Pharmacodynamics (PK/PD) of Caspofungin in Intensive Care Unit (ICU) Patients. An Open Observational Study for Antifungal Treatment's Optimization

Critical Illness | Infection
Merck Sharp & Dohme LLC

Completed

A Study of Caspofungin (MK-0991) in Japanese Children and Adolescents With Documented Candida or Aspergillus Infections (MK-0991-074)

Candidiasis, Invasive | Aspergillosis | Candidiasis, Esophageal
F2G Biotech GmbH
University Hospital of Cologne

Withdrawn

Study on Safety and Pharmacokinetics of Intravenous F901318 for Fungal Prophylaxis in AML Patients (SAFEGUARD)

Acute Myeloid Leukemia | Pulmonary Aspergillosis - Invasive
Medical University of Lublin

Unknown

Pharmacokinetics of Caspofungin

Critical Illness | Septic Shock | Fungal Infection
Outcome Rea
Assistance Publique - Hôpitaux de Paris

Completed

Impact of a Loading Dose of Caspofungin in Invasive Candidiasis in ICU Patients (CASPOLOAD)

Candida Infections

France
Merck Sharp & Dohme LLC

Completed

A Multicenter, Randomized, Double-Blind, Comparative Study to Evaluate the Safety, Tolerability, and Efficacy of 2 Dosing Regimens of an Antifungal Drug in the Treatment of Fungal Infections in Adults (0991-801)(COMPLETED)

Invasive Candidiasis
Merck Sharp & Dohme LLC
Mycoses Study Group

Terminated

Pilot Feasibility Study With Patients Who Are at High Risk For Developing Invasive Candidiasis in a Critical Care Setting (MK-0991-067)

Invasive Candidiasis
Merck Sharp & Dohme LLC

Completed

A Study of Caspofungin Acetate (MK0991) for the Treatment of Esophageal Candidiasis or Invasive Candidiasis in Chinese Adults (MK-0991-066)

Fungal Infection
Merck Sharp & Dohme LLC

Completed

A Clinical Study of MK0991 (Caspofungin) in Japanese Patients With Deep-seated Candida or Aspergillus Infections (0991-062)(COMPLETED)

Fungal Infection
Merck Sharp & Dohme LLC

Completed

Documented Candida or Aspergillus Infections in Pediatric Patients (0991-043)

Candidiasis | Aspergillosis
Merck Sharp & Dohme LLC

Completed

Caspofungin for the Treatment of Non-blood Candida Infections (0991-045)

Candidiasis
Merck Sharp & Dohme LLC

Completed

Open, Pharmacokinetic Study of Caspofungin in Neonates and Infants (0991-058)

Candidiasis
Merck Sharp & Dohme LLC

Completed

A 28 - 90 Days Study to Evaluate the Safety, Tolerability, and Efficacy of Caspofungin Injection as Empirical Therapy in Indian Adults With Persistent Fever and Neutropenia (0991-053)(COMPLETED)

Fungal Infection
Merck Sharp & Dohme LLC

Completed

Open, Pharmacokinetic Study of Caspofungin Acetate in Immunocompromised Young Children With Febrile Neutropenia (0991-042)

Fungal Infection
Merck Sharp & Dohme LLC

Completed

MK0991 Versus Amphotericin B for Empirical Therapy in Febrile, Neutropenic Pediatric Patients (0991-044)

Neutropenia | Fever
Texas Tech University Health Sciences Center
University of Texas Southwestern Medical Center; National Center for Research...

Completed

Effect of Weight and/or Obesity on Caspofungin Drug Concentrations

Obesity | Fungal Infection

United States
Nanjing PLA General Hospital

Completed

the Influence of Prophylactic and Empirical Anti-fungal Treatment in Severe Sepsis Patients With Perforations

Intra-abdominal Perforation
Shanghai Jiao Tong University School of Medicine

Unknown

Caspofungin Based Combined Anti-fungal Therapy for Proven or Probable Invasive Fungal Infection

Leukemia | Transplantation, Hematopoietic Stem Cell

China
Pfizer

Terminated

Risk Of Severe Hepatic Injury In Patients With Invasive Candidiasis Treated With Echinocandins

Candidemia | Invasive Candidiasis
Merck Sharp & Dohme LLC

Completed

Evaluate the Safety and Efficacy of Caspofungin Acetate as Empirical Therapy in Chinese Adults With Persistent Fever and Neutropenia (0991-055)

Fungal Infection
University Medical Center Groningen

Completed

Optimal Dosage of Caspofungin in Critically Ill Patients

Critically Ill | Suspected Invasive Candidiasis

Netherlands

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