Search clinical trials for: cathepsin L

Total 490906 results

Sohag University

Not yet recruiting

Evaluation of Serum and Tissue Cathepsin L in Non-segmental Vitiligo Patients

Vitiligo
Assiut University

Not yet recruiting

Diagnostic Value of Serum Cathepsin S and Chromogranin A in DKD

Diabetic Kidney Disease
Ankara City Hospital Bilkent
Gazi University

Recruiting

The Relationship of Cortical Excitability, Cognitive Functions, and Peripheral Signaling Molecules Following Acute Exercise

Healthy

Turkey
SphinCS Lyso Gemeinnutzige UG (Haftungsbeschrankt)

Recruiting

Registry Gangliosidoses

Gangliosidoses | Galactosialidosis | Sialidosis | GM1 Gangliosidosis | Tay-Sachs Disease | Sandhoff Disease | Morquio B Disease | Gm2-Gangliosidosis, Variant B1 | GM2 Activator Deficiency

Germany
Insmed Incorporated

Available

An Expanded Access Study to Assess Brensocatib for Participants With Non-Cystic Fibrosis Bronchiectasis

Non-Cystic Fibrosis Bronchiectasis
Sanliurfa Mehmet Akif Inan Education and Research...

Completed

The Role of Pentraxin 3 and Cathepsin B Levels in Preeclamptic Pregnancy

Pre-Eclampsia | Cathepsin B Level | Pentraxin 3 Level

Turkey
Centre Hospitalier Universitaire de Saint Etienne

Terminated

Transplacental Transmission of COVID-19

SARS-COV-2 Infection

France
University Hospital, Tours

Completed

Lymphangioleiomyomatosis, a Study on Cathepsin K (LAM-CAK)

Tuberous Sclerosis Complex | Lymphangioleiomyomatosis

France
Nicolaus Copernicus University

Completed

Oxidoreductive Balance and Lysosomal Activity in Cancer Patients.

Neoplasms | Inflammation | Oxidative Stress | Antioxidants | Lipid Peroxidation | Lysosome Alteration

Poland
University Hospital, Tours

Completed

Respiratory Cathepsins, Proteases Inhibitors and Glycosaminoglycans (GAG) in Mucopolysaccharidosis (RespiGAG)

Mucopolysaccharidoses

France
Peking Union Medical College Hospital
Stanford University

Unknown

68Ga-BMV101 PET/CT in Patients With Idiopathic Pulmonary Fibrosis

Idiopathic Pulmonary Fibrosis

China
David Kirsch
American Society of Clinical Oncology

Completed

Cathepsin Activatable Fluorescent Probe (LUM015)

Sarcoma | Soft Tissue Sarcoma | Breast Cancer

United States
Johnson & Johnson Pharmaceutical Research & Development...

Completed

Safety and Effectiveness Study of RWJ-445380 Cathepsin-S Inhibitor in Patients With Active Rheumatoid Arthritis Despite Methotrexate Therapy

Rheumatoid Arthritis

United States, Poland, Germany, Mexico, Brazil, Czech Republic, Argentina
Virobay Inc.

Completed

Safety Study of Single Oral Doses of VBY-036 in Healthy Volunteers (VBY036P1A)

Healthy

United States
Novartis Pharmaceuticals

Completed

Efficacy and Safety of AAE581 in Postmenopausal Women With Osteopenia/Osteoporosis.

Osteoporosis
University Medical Centre Ljubljana

Unknown

The Role of Cathepsin X in Infection With the Helicobacter Pylori

Persistence of Infection With Helicobacter Pylori

Slovenia
Kaohsiung Medical University Chung-Ho Memorial...

Completed

Recurrence and Distant Metastases in Hepatocellular Carcinoma Treated by Transcatheter Arterial Chemoembolization

Hepatocellular Carcinoma

Taiwan
Leiden University Medical Center

Completed

The Effect of Doxycycline on Matrix Metalloproteinase Expression and Activity in the Abdominal Aneurysm

Aortic Aneurysm, Abdominal

Netherlands
Merck Sharp & Dohme LLC

Not yet recruiting

Substudy 06D: Combination Therapies in Second Line (2L) Gastroesophageal Adenocarcinoma (MK-3475-06D/Keymaker-U06)

Esophageal Cancer | Esophageal Neoplasms | Gastroesophageal Adenocarcinoma | Gastroesophageal Junction
University Hospital, Rouen

Not yet recruiting

Functional Residual Capacity and Alveolar Recruitment in Single-lung Ventilation: a Randomized Study (OLVEELV)

Lung Injury
The University of Texas Health Science Center at...
Baptist Health Foundation of San Antonio

Recruiting

Prevention of Progression of Prediabetes, Obesity and CV Risk (Pre-DM)

Cardiovascular Diseases | Weight, Body | Pre-Diabetes

United States
University Medical Center Groningen

Not yet recruiting

PIRATES Phase I Trial (PIRATES)

Head and Neck Cancer | Oropharyngeal Cancer

Netherlands
McMaster University

Not yet recruiting

Accelerated Intermittent Theta-burst Stimulation to Modify Cognitive Function and Balance in Dementia and Memory Loss

Dementia Alzheimers

Canada
M.D. Anderson Cancer Center
Regeneron Pharmaceuticals

Not yet recruiting

Phase II Trial of Ubamatamab Alone or in Combination With Cemiplimab in MUC16-Expressing SMARCB1-Deficient Malignancies

SMARCB1-Deficient Malignancies

United States
Shahirose Sadrudin Premji
Canadian Institutes of Health Research (CIHR)

Not yet recruiting

A Chinese Version of the Thinking Health Program for East Asian Pregnant Immigrant People in Canada

Perinatal Depression

Canada
Huai'an First People's Hospital
The Affiliated Hospital of Xuzhou Medical University; The First People's Hospital... and other collaborators

Recruiting

A Clinical Study Evaluating the Safety and Efficacy of ZRMT Regimen in the Treatment of PCNSL

Primary Central Nervous System Lymphoma

China
Hôpital NOVO
University of Brighton

Not yet recruiting

Observational Study of Musculoskeletal Patients in an Emergency Department in France (SKUAD-P)

Musculoskeletal Pain

France
Centre Hospitalier Universitaire de Nīmes

Not yet recruiting

Follow-up of Migraine Patients on Eptinezumab (EPTI-CO)

Migraine

France
Anhui Provincial Hospital

Not yet recruiting

SV2A-PET/CT and PET/MRI Combined Clinical Criteria Score in the Diagnosis of Early Cognitive Alteration

Alzheimer Disease
Johns Hopkins University

Not yet recruiting

Nutrition Optimization and Community Upliftment for Postpartum Recovery: Intervention to Support Healing After Hypertensive Disorders of Pregnancy (NOURISH-HDP)

Obesity, Maternal | Gestational Hypertension | Pre-Eclampsia; Complicating Pregnancy | Eclampsia; Complicating Pregnancy

United States
Givaudan France Naturals
Analyze & Realize; University Hospital of Leuven Leuven

Not yet recruiting

The Effect of a Ginger Supplement on Digestive Complaints in Healthy Adults Versus a Placebo (GIGI)

Dyspepsia
Hartford Hospital

Recruiting

Target ADHD Executive Working Memory Replication Study

ADHD

United States
Islamia University of Bahawalpur

Not yet recruiting

Efficacy of Cognitive Behavior Therapy in the Treatment of Chronic Pelvic Pain in Women

Chronic Pelvic Pain Syndrome
Shanghai East Hospital

Recruiting

Chemokine and Co-stimulatory Molecule-modified Mesenchymal Stem Cells for the Treatment of Advanced Colorectal Cancer

Advanced Colorectal Cancer

China
Hospital Universitario Getafe

Recruiting

Biomarkers of Inflammation and Endothelial Dysfunction in Patients With Myocardial Infarction With Non-obstructive Coronary Arteries (IMACORN-INFLI)

Myocardial Infarction | Inflammation | Biomarkers | Endothelial Dysfunction | MINOCA

Spain
Liu Shuxian
Harbin Medical University

Not yet recruiting

Construction and Preliminary Application of COM-B Based Sedentary Behavioural Booster Intervention Programme for Elderly Stroke Patients

Stroke
Brown University
The Miriam Hospital

Not yet recruiting

Musical Playlist of the Grief Journey

Music Therapy | Bereavement
Marmara University

Not yet recruiting

The Effectiveness of Online Interpersonal Relationships-Based Pyschoeducation in Increasing Sexual Interest and Arousal in Women With Sexual Interest and Arousal Disorder

Sexual Arousal Disorder | Sexual Desire Disorder
Shanghai Zhongshan Hospital

Not yet recruiting

Efficacy and Safety of Oxycodone Hydrochloride for Long-term Analgesia in ICU Patients

Analgesia | Mechanical Ventilation | Remifentanil | Postoperative | Oxycodone

China
Ohio State University
Patient-Centered Outcomes Research Institute; The George Washington University...

Not yet recruiting

DECIDE: A Comparative Effectiveness Trial of Metformin Versus Insulin for the Treatment of Gestational Diabetes (DECIDE)

Pregnancy, High Risk | Gestational Diabetes Mellitus

United States
Zachary Zumsteg

Not yet recruiting

Using CircuLating Tumor DNA to Risk Adapt Post-Operative Therapy for HPV-associated Oropharyngeal Cancer

Carcinoma | Oropharyngeal Cancer

United States
Lawson Health Research Institute

Not yet recruiting

Patient Reported Outcomes Targeting Early Chest Tube Removal (PROTECTR) Study (PROTECTR)

Chest Tube Removal | Lung Surgery | ERAS

Canada
University of Chicago

Not yet recruiting

Using Text Messages to Improve Oral Chemotherapy for Adolescents and Young Adults With Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia

United States
University of California, Irvine

Not yet recruiting

Relationship bw Image-deriv Features of Intraoperative ICG Visualiz of NVBs During RARP & Functional Outcome

Prostate Adenocarcinoma

United States
Medstar Health Research Institute
Medtronic

Recruiting

Optimal Pacing Rate for Cardiac Resynchronization Therapy (OPT-RATE AF)

Atrial Fibrillation, Persistent

United States
Cutting Edge SAS

Not yet recruiting

Bicentric Clinical Investigation to Assess Safety and Performance of LuxHighAdd IOL (HIGHADD)

Cataract

France
Ball State University

Recruiting

Postprandial Effects of Animal Versus Plant-Based Protein

Overweight or Obesity

United States
University of Valencia

Not yet recruiting

TRAK vs Standard Home-based Exercise in Low Back Pain

Low Back Pain
Johns Hopkins University

Not yet recruiting

Nutrition Optimization and Community Upliftment for Postpartum Recovery (NOURISH-GDM)

Gestational Diabetes | Obesity, Maternal

United States
Baylor University
National Institute on Aging (NIA); Baylor Scott and White Health; University...

Not yet recruiting

Paper-Based and Smartphone-Based Memory Supports

Alzheimer Disease | Mild Cognitive Impairment | Dementia, Mild

United States

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