Search clinical trials for: ceftazidime avibactam

Total 115 results

Hospital Italiano de Buenos Aires

Not yet recruiting

Mortality of MBL-producing Enterobacteriaceae Bacteremias With the Combined Use of Ceftazidime-avibactam and Aztreonam vs. Other Active Antibiotics. A Multicenter Target Trial Emulation.

Bacteremia
Sichuan Provincial People's Hospital

Not yet recruiting

Precise Treatment of Ceftazidime-Avibactam in Patients With CRO Infections Under the Guidance of TDM and PPK Model

ECMO | Carbapenem-Resistant Enterobacteriaceae Infection
National University of Singapore
Pfizer; Biomerieux inc

Recruiting

EaRly impAct theraPy With Ceftazidime-avibactam Via rapID Diagnostics (RAPID)

Hospital-acquired Pneumonia | Ventilator Associated Pneumonia | Healthcare Associated Infection | Blood Stream Infections | Carbapenem-Resistant Enterobacteriaceae Infection

Taiwan, Malaysia, Thailand
Phramongkutklao College of Medicine and Hospital
Silpakorn University

Recruiting

Dose Optimization by Pharmacokinetic/Pharmacodynamic of Antibiotics to Improve Clinical Outcome of Carbapenem Resistant Klebsiella Pneumoniae Bloodstream Infections in Critically Ill Patients at Phramongkutklao Hospital

Carbapenem Resistant Klebsiella Pneumoniae

Thailand
Pfizer

Recruiting

A Study to Learn About the Study Medicine Zavicefta After it is Released Into the Markets in Korea

Hospital-acquired Pneumonia | Complicated Intra-abdominal Infection | Complicated Urinary Tract Infection

Korea, Republic of
Policlinico Hospital
Pfizer

Recruiting

Nosocomial Infections in Patients With ARDS Treated With ECMO (INF-ECMO)

Acute Respiratory Distress Syndrome | Extracorporeal Membrane Oxygenation Complication | Nosocomial Infection

Italy
Pfizer

Recruiting

Real-World Study of Ceftazidime Avibactam in China (REACT)

Hospital Acquired Pneumonia | Complicated Intra Abdominal Infections | Ventilator Acquired Pneumonia

China
First Affiliated Hospital of Zhejiang University

Recruiting

Clinical Study on Monitoring the Plasma Concentration of Ceftazidime-Avibactam in Critically Ill Patients

Severe Sepsis

China
Uppsala University
Karolinska University Hospital; Sahlgrenska University Hospital, Sweden; University... and other collaborators

Recruiting

Use of New Antibiotics in Sweden

Multi-antibiotic Resistance

Sweden
King Faisal Specialist Hospital & Research Center

Terminated

Ceftazidime-Avibactam Use in Critically Ill Patients With Carbapenem-Resistant Enterobacteriaceae Infections (AVI-ICU)

Carbapenem-Resistant Enterobacteriaceae Infection

Saudi Arabia
Pfizer
Allergan

Terminated

Evaluation of Pharmacokinetics, Safety, and Tolerability of Ceftazidime-avibactam in Neonates and Infants. (NOOR)

Gram-negative Bacterial Infection

United States, Hungary, Slovakia, Taiwan, India, Estonia, Greece, Italy
Pfizer

Completed

Study to Assess Efficacy and Safety of PF-06947386 in Japanese Adult Patients With Complicated Intra-abdominal Infection

Complicated Intra-abdominal Infection

Japan
Pfizer

Completed

Real-World Observational Study Of Zavicefta to Characterize Use Patterns (EZTEAM)

Infection

France, United Kingdom, Spain, Colombia, Argentina, Germany, Italy, Austria, Russian Federation, Greece
Pfizer

Completed

Efficacy and Safety of CAZ-AVI in the Treatment of Infections Due to Carbapenem-resistant G- Pathogens in Chinese Adults

Bacteremia | Urinary Tract Infection | Intra-abdominal Infection | Hospital Acquired Pneumonia | Acute Pyelonephritis | Ventilator-associated Pneumonia

China
West Virginia University

Enrolling by invitation

Comparing Oral Versus Parenteral Antimicrobial Therapy (COPAT)

Skin and Soft Tissue Infection | Gastrointestinal Infection | Pulmonary Infection | Bone and Joint Infection | Endovascular Infection | Genitourinary Infection

United States
Pfizer

Completed

Efficacy and Safety of Ceftazidime-Avibactam (CAZ-AVI) in Chinese Participants With HAP (Including VAP)

Hospital-Acquired Pneumonia

China
Pfizer

Completed

Retrospective Analysis of Real World Use of Ceftazidime-avibactam in the Management of Gram Negative Infections

Gram Negative Infections

India
Pfizer
AbbVie

Terminated

Single-dose PK Study of Ceftazidime-Avibactam In Hospitalized Children Receiving Systemic Antibiotics for Nosocomial Pneumonia

Hospitalized Children With Suspected or Confirmed Nosocomial Pneumonia

Taiwan, China
National Institute of Allergy and Infectious Diseases...

Completed

A Trial to Evaluate the Pharmacokinetics and Safety of AVYCAZ(R) in Combination With Aztreonam

Bacterial Infection

United States
Maimónides Biomedical Research Institute of Córdoba

Completed

Impact of Ceftazidime / Avibactam Treatment vs Better Available Therapy on Mortality of Patients With Infections Caused by Carbapenem-resistant Enterobacteria (CAVICOR)

Carbapenem-Resistant Enterobacteriaceae Infection

Spain
University of Pittsburgh
Allergan

Completed

Pharmacokinetics of Ceftazidime-avibactam Among Critically-ill Patients Receiving CVVHDF

Bacterial Infections

United States
King Abdul Aziz Specialist Hospital

Completed

Usage of Meropenem/Gentamicin Versus Ceftazidime/Avibactam in ARDS

Ventilator Associated Pneumonia

Saudi Arabia
Fundación Pública Andaluza para la gestión de la...

Unknown

Study to Optimize the Use of New Antibiotics (NEW_SAFE)

Bacterial Infections | Fungal Infection

Spain
Temple University
Allergan

Unknown

Study of Ceftazidime-Avibactam Blood Concentrations in Intensive Care Unit Patients With Renal Failure Requiring Continuous Dialysis

Critical Illness | Bacterial Infections | Renal Failure

United States
Michigan State University

Completed

A Study of Avycaz (Ceftazidime/Avibactam) Pharmacokinetics/Pharmacodynamics (PK/PD) in Critically Ill Patients

Pharmacokinetics of Avycaz in ICU Patients
University of Southern California

Completed

Steady-state Pharmacokinetics of Ceftazidime/Avibactam in Cystic Fibrosis

Cystic Fibrosis

United States
Pfizer

Completed

Evaluation of Safety,Pharmacokinetics and Efficacy of CAZ-AVI With Metronidazole in Children Aged 3 Months to 18 Years Old With Complicated Intra-abdominal Infections (cIAIs).

Complicated Intra-abdominal Infections

Spain, Taiwan, United States, Poland, Hungary, Czechia, Turkey, Greece, Romania, Russian Federation
Pfizer
PRA Health Sciences

Completed

Evaluation of Safety, Pharmacokinetics and Efficacy of Ceftazidime and Avibactam (CAZ-AVI ) Compared With Cefepime in Children From 3 Months to Less Than 18 Years of Age With Complicated Urinary Tract Infections (cUTIs)

Complicated Urinary Tract Infections

United States, Taiwan, Turkey, Czechia, Hungary, Greece, Poland, Romania, Russian Federation
Pfizer

Completed

Prospective Multicenter Doubleblind Randomized Study of NXL104/Ceftazidime + Metronidazole vs. Meropenem in Treatment of Complicated Intra-abdominal Infections

Complicated Intra-abdominal Infections

United States, Lebanon, France, Romania, Bulgaria, India, Poland, Russian Federation
Pfizer

Completed

Comparative Study of NXL104/Ceftazidime Versus Comparator in Adults With Complicated Urinary Tract Infections

Complicated Urinary Tract Infection

United States, Lebanon, Jordan
Pfizer
Forest Laboratories

Completed

Ceftazidime-Avibactam for the Treatment of Infections Due to Ceftazidime Resistant Pathogens

Complicated Intra-abdominal Infection | Complicated Urinary Tract Infection

Croatia, Bulgaria, Korea, Republic of, Mexico, Peru, Russian Federation, Spain, Turkey, Poland, Romania, Ukraine, South Africa, Argentina, Israel, United States, Philippines, France, Czechia
Pfizer
Forest Laboratories

Completed

Compare Ceftazidime-Avibactam + Metronidazole Versus Meropenem for Hospitalized Adults With Complicated Intra-Abdominal Infections

Complicated Intra-Abdominal Infection

United States, Croatia, Bulgaria, Peru, Russian Federation, Latvia, Ukraine, Mexico, Romania, South Africa, Argentina, Czechia, Hungary, Israel, Taiwan, India, Thailand, Spain, Netherlands, Malaysia
Pfizer
Forest Laboratories

Completed

Ceftazidime-Avibactam Compared With Doripenem Followed by Oral Therapy for Hospitalized Adults With Complicated UTIs (Urinary Tract Infections)

Complicated Urinary Tract Infection (cUTI) Including Acute Pyelonephritis

Croatia, Brazil, Bulgaria, Korea, Republic of, Russian Federation, Hungary, Poland, Romania, Ukraine, Argentina, Israel, Portugal, Greece, Taiwan, Japan, Slovakia, Serbia, United States, Mexico, Germany, Turkey, Czechia
Pfizer
Forest Laboratories

Completed

Ceftazidime-Avibactam Compared With Doripenem Followed by Oral Therapy for Hospitalized Adults With Complicated UTIs (Urinary Tract Infections)

Complicated Urinary Tract Infection (cUTI) Including Acute Pyelonephritis

Croatia, Bulgaria, Korea, Republic of, Mexico, Peru, Poland, Russian Federation, Spain, Romania, Ukraine, United States, Argentina, Czechia, Israel, Taiwan, Germany, Italy
Pfizer
Forest Laboratories

Completed

Safety and Tolerability of Ceftazidime-Avibactam for Pediatric Patients With Suspected or Confirmed Infections

Systemic Infections

United States
Pfizer

Completed

Compare Ceftazidime-Avibactam + Metronidazole vs Meropenem for Hospitalized Adults With Complicated Intra-Abd Infections (RECLAIM3)

Complicated Intra-abdominal Infection

Korea, Republic of, Vietnam, China
Pfizer

Completed

A Study Comparing Ceftazidime-Avibactam Versus Meropenem in Hospitalized Adults With Nosocomial Pneumonia

Ventilator-associated Pneumonia (VAP) | Nosocomial Pneumonia (NP)

Bulgaria, France, Italy, Korea, Republic of, Mexico, Peru, Poland, Russian Federation, Spain, Turkey, United Kingdom, Vietnam, Philippines, China, Ukraine, Argentina, Brazil, Hungary, Romania, India, Japan, Taiwan, Latvia, Czechia, Slov... and more
Pfizer

Completed

A Phase I Study to Assess the Safety, Tolerability and PK of Ceftazidime-Avibactam in Healthy Chinese Subjects

Healthy Volunteers

China
Pfizer

Completed

A Study to Investigate the Effect of Administration of Ceftazidime-avibactam (CAZ-AVI) and Ceftaroline Fosamil -Avibactam (CXL) on the Intestinal Flora of Healthy Volunteers

Pharmacokinetics | Safety | Open Label | CAZ-AVI | CXL | Effect on Intestinal Flora

Sweden
Pfizer

Completed

A Single-centre, Randomised, Double-blind, Placebo-controlled, Four Way Crossover Phase I Study to Investigate the Effect on QT/QTc Interval of Ceftazidime NXL104 or Ceftaroline Fosamil NXL104, Compared With Placebo, Using Moxifloxacin (Avelox®) as a Positive Control, in Healthy Male Volunteers

Healthy Male Volunteers

United States
Pfizer

Completed

A Study to Assess the Levels of Two Antibiotics in the Blood When Given Together and Separately

Healthy

United Kingdom
Pfizer

Completed

Study to Assess the Concentration of Avibactam and Ceftazidime in Epithelial Lining Fluid and Plasma

Healthy

United Kingdom
Pfizer

Completed

A Study to Assess the Safety, Tolerability and Pharmacokinetics of NXL104 Alone and in Combination With Ceftazidime Administered as Single and Repeated Intravenous Doses in Healthy Japanese Subjects

Healthy Male and Female Japanese Volunteers

United States
Forest Laboratories

Terminated

Comparative Study of Ceftazidime-Avibactam Versus Standard of Care as Therapy in Febrile Neutropenic Adults With Cancer

Neoplasms | Febrile Neutropenia

United States
Massachusetts General Hospital
National Institute of Allergy and Infectious Diseases (NIAID)

Not yet recruiting

Optimizing the Diagnostic Approach to Cephalosporin Allergy Testing (DACAT)

Drug Hypersensitivity | Drug-Induced Anaphylaxis | Antibiotic Allergy | Drug Allergy | Beta Lactam Adverse Reaction | Cephalosporin Allergy | Cephalosporin Reaction

United States
Qianfoshan Hospital

Recruiting

Drug Resistance Mechanism of Enterobacteriaceae and Its Strategies

Carbapenem-Resistant Enterobacteriaceae Infection

China
Pfizer

Recruiting

Study of 2 Medicines (Aztreonam and Avibactam) Compared to Best Available Therapy for Serious Gram-negative Infections

Gram-negative Bacterial Infections

Spain, Taiwan, United States, Hungary, India, China, Turkey, Greece, Czechia
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Not yet recruiting

To Evaluate the Pharmacokinetic Effects of TQD3606 for Injection in Healthy Adult Subjects

Infections

China
Children's Hospital of Fudan University

Recruiting

PK/PD of Ceftazidime Avitbatan Sodium in Children With Severe Infection

Sepsis | Antibiotic Reaction

China
Murdoch Childrens Research Institute

Recruiting

Early Versus Late Stopping of Antibiotics in Children With Cancer and High-risk Febrile Neutropenia (ELSA-FN)

Febrile Neutropenia

Australia

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