Search clinical trials for: ctDNA Methylation Haplotypes

Total 798 results

Fudan University
Southern Medical University, China

Completed

The Implication of Plasma ctDNA Methylation Haplotypes in Detecting Colorectal Cancer and Adenomas

Colorectal Cancer | Adenoma

China
Fudan University

Unknown

Use of Plasma ctDNA Methylation Haplotypes in Detecting Local Residual or Lymph Node Metastasis

Colorectal Cancer | Lymph Node Metastases

China
Shanghai Chest Hospital

Recruiting

Predicting Non-small Cell Lung Cancer (NSCLC) Lymph Node Metastasis: Integrating Circulating Tumor DNA (ctDNA) Mutation/ Methylation Profiling With Positron Emission Tomography-computed Tomography (PET-CT) Scan

Carcinoma | Non-small Cell Lung Cancer

China
Singlera Genomics Inc.
Shanghai Zhongshan Hospital

Recruiting

Clinical Research on Dynamic Monitoring MRD Via Plasma ctDNA After Systemic Therapy of Hepatocellular Carcinoma

Hepatocellular Carcinoma

China
Sir Run Run Shaw Hospital

Recruiting

Circulating Tumor DNA Methylation Guiding Postoperative Adjuvant Chemotherapy in Stage III Colorectal Cancer (cmPAT)

Colorectal Cancer

China
Fudan University

Recruiting

Circulating Tumor DNA Methylation Guided Postoperative Follow-up Strategy for Non-metastatic Colorectal Cancer

Non-metastatic Colorectal Cancer | Circulating Tumor DNA Methylation

China
Singlera Genomics Inc.
Beijing Friendship Hospital

Recruiting

Study on Early Auxiliary Diagnosis and Postoperative Recurrence Monitoring of Breast Cancer

Breast Cancer

China
Lei Li

Recruiting

ctDNA Methylation for Detecting Ovarian Cancer

Epithelial Ovarian Cancer | Circulating Tumor DNA | CA125 | DNA Methylation | Non-invasive Diagnosis | Human Epididymis Protein 4 | Imaging Evaluation | Survival Prognosis | ROMA Index

China
Lei Li

Recruiting

ctDNA Methylation for Epithelial Ovarian Cancer

Epithelial Ovarian Cancer | Circulating Tumor DNA | CA125 | DNA Methylation | Non-invasive Diagnosis | Human Epididymis Protein 4 | Imaging Evaluation | Survival Prognosis

China
Parc de Salut Mar
GUARDANT HEALTH

Recruiting

Molecular Profiling and Dynamic Changes of ctDNA in Unresectable Locally Advanced NSCLC

Lung Cancer | Stage III Lung Cancer | Unresectable Lung Carcinoma

Spain
Cancer Institute and Hospital, Chinese Academy...
Cangzhou Central Hospital; Weifang Medical University; Heji Hospital affiliated... and other collaborators

Recruiting

Early Screening of Colorectal Cancer Based on Plasma Multi-omics Combining With Artificial Intelligence (RECOMMEND)

Colorectal Cancer | Colorectal Adenoma

China
Institute of Hematology & Blood Diseases Hospital
MethylGene Tech Co., Ltd. China

Recruiting

ctDNA Methylation Sequencing for Myeloma

Multiple Myeloma

China
Ruijin Hospital
Guangzhou Burning Rock Dx Co., Ltd.

Recruiting

AssesSment of Early-deteCtion basEd oN liquiD Biopsy in PANCEATIC Cancer (ASCEND-PANCREATIC)

Cancer

China
Singlera Genomics Inc.
Second Affiliated Hospital, School of Medicine, Zhejiang University

Recruiting

ctDNA Methylation Application in Postoperative Relapse and Adjuvant Chemotherapy Efficacy Evaluation

Cancer Colorectal

China
Singlera Genomics Inc.
Peking University Shougang Hospital

Recruiting

A Prospective Cohort Study on Colorectal Cancer Screening in Community Population

Colorectal Cancer

China
Singlera Genomics Inc.
Cancer Institute and Hospital, Chinese Academy of Medical Sciences

Recruiting

Application of Polygenic Methylation Markers in Postoperative Recurrence Monitoring of Colorectal Cancer

Colorectal Cancer

China
Singlera Genomics Inc.
China-Japan Friendship Hospital

Recruiting

To Establish a Molecular Typing System for Early Diagnosis of Lung Cancer

Lung Cancer

China
Geneplus-Beijing Co. Ltd.
Beijing Hospital; Emergency General Hospital

Recruiting

Benign/Malignant Pulmonary Nodule Classification Based on High-throughput Whole-genome Methylation Sequencing(GM-seq)

Pulmonary Nodule, Solitary | Whole-genome Methylation Sequencing

China
Shanghai Zhongshan Hospital
Guangzhou Burning Rock Bioengineering Ltd.

Recruiting

AssesSment of Early-deteCtion basEd oN liquiD Biopsy in GASTRIC Cancer, ASCEND-Gastric (ASCEND-Gastric)

Cancer

China
National Taiwan University Hospital

Recruiting

Developing Novel Circulating Epigenetic Biomarkers for Early Detection of Lung Cancer

Lung Cancer

Taiwan
Fudan University
RenJi Hospital; Hebei Medical University Fourth Hospital; Shanghai University... and other collaborators

Recruiting

Dynamic Monitoring of ctDNA Methylation to Predict Relapse in Colorectal Cancer After Radical Resection (POSTCA)

Colorectal Cancer | Circulating Tumor DNA | Surveillance | Methylation

China
Singlera Genomics Inc.

Completed

Clinical Validation of ColonAiQ (a Blood-based Assay Targeting ctDNA Methylation) for Colorectal Cancer Detection

Colorectal Cancer

China
Nanfang Hospital, Southern Medical University

Active, not recruiting

Comparison of Diagnostic Sensitivity Between ctDNA Methylation and CEA in Colorectal Cancer

Colorectal Tumor

China
Singlera Genomics Inc.
Fudan University; Shanghai Zhongshan Hospital; Shanghai Public Health Clinical... and other collaborators

Completed

Establishment of Molecular Classification Models for Early Diagnosis of Digestive System Cancers

Hepatocellular Carcinoma | Colorectal Cancer | Esophageal Cancer | Gastric (Stomach) Cancer

China
Changhai Hospital
The Second Hospital of Hebei Medical University; Qilu Hospital of Shandong... and other collaborators

Completed

A Study on a Blood-based Dual-target Test for CRC Detection

Colorectal Cancer | Colorectal Adenoma

China
AnchorDx Medical Co., Ltd.
The First Affiliated Hospital with Nanjing Medical University; The First Affiliated... and other collaborators

Active, not recruiting

Diagnostic and Monitoring Significance of ctDNA Methylation Analysis by NGS in Benign and Malignant Pulmonary Nodules

Pulmonary Nodules

China
HKGepitherapeutics
International Centre for Diarrhoeal Disease Research, Bangladesh

Completed

HCC Screening Using DNA Methylation Changes in ctDNA

Hepatocellular Carcinoma

Bangladesh
Peking University People's Hospital

Unknown

Monitoring of Circulating Tumor DNA and Its Aberrant Methylation in the Surveillance of Surgical Lung Cancer Patients (MEDAL, MEthylation Based Dynamic Analysis for Lung Cancer). (MEDAL)

Carcinoma | NSCLC | Lung Cancer | Lung Neoplasm

China
Shanghai Chest Hospital
Singlera Genomics Inc.

Unknown

Non-Invasive ctDNA Methylation Detection for Lung Nodule Patients

Lung Nodule

China
RenJi Hospital

Completed

Plasma ctDNA Detection in Diagnosis of Epithelial Ovarian Cancer. (ctDNA_EOC)

Epithelial Ovarian Cancer

China
Sidney Kimmel Comprehensive Cancer Center at Johns...
Canon Medical Systems, USA

Not yet recruiting

Exploration of Personalized Biomarkers During Neoadjuvant Radiation Therapy for Spinal and Sacral Chordoma (Canon)

Chordoma of Sacrum | Chordoma of Spine | Chordoma of Skull Base
UNICANCER
Natera, Inc.

Not yet recruiting

Decreasing Treatment for Metastatic HER2-Positive Breast Cancer With Undectable Cancer Levels in Blood Tests. (HEROES)

Metastatic Breast Cancer | HER2-positive Breast Cancer
Zhujiang Hospital

Not yet recruiting

Compare the Accuracy of ctDNA-MRD and MVI Result in Predicting Postoperative Recurrence of Hepatocellular Carcinoma

Recurrence | Surgery | Hepatocellular Carcinoma Resectable

China
Sun Yat-sen University
Wuzhou Red Cross Hospital; Fujian Cancer Hospital; Zhongshan People's Hospital... and other collaborators

Recruiting

Diagnostic Accuracy of EBV C Promoter Methylation Kit in Nasopharyngeal Carcinoma

Nasopharyngeal Carcinoma

China
University Hospital, Rouen

Not yet recruiting

De-scalation or swItch of Treatment According to Circulating tuMOr DNA Variation After 2 Cycles of Doublet Chemotherapy Plus Targeted Agent in Metastatic Unresectable Colorectal Cancer (DIAMOND)

Metastatic Colon Cancer
Fudan University

Recruiting

Exploration of Therapeutic Strategies for NeoRAS Wild-type Metastatic Colorectal Cancer Based on Circulating Tumor DNA

Colorectal Cancer Metastatic

China
UMC Utrecht
The Netherlands Cancer Institute; Personal Genome Diagnostics (PGDx)

Recruiting

Circulating Tumor DNA Based Adjuvant Chemotherapy in Stage II Colon Cancer Patients: the MEDOCC-CrEATE Trial (CrEATE)

Recurrence | Circulating Tumor DNA | Colon Cancer Stage II

Netherlands
University Hospital of Ferrara
Azienda Ospedaliera Universitaria Policlinico; Azienda Ospedaliera di Padova; Fondazione IRCCS San Gerardo dei Tintori

Not yet recruiting

Effect of Infections and Global DNA Methylation on Frailty Trajectories in Hospitalized Older Patients (INFRAGEN) (INFRAGEN)

Inflammation | Frailty | Aging | Telomere Shortening | Hospital Infection
Changhai Hospital

Not yet recruiting

Urine DNA Methylation Detection for Hematuria Evaluation

Bladder Cancer | Urothelial Carcinoma | Ureter Cancer | Hematuria | Renal Pelvis Cancer

China
Sun Yat-sen University

Not yet recruiting

ctDNA-MRD Guided Consolidation Toripalimab in Stage IB-IIIA NSCLC (CONTINUE)

Lung Cancer, Nonsmall Cell
The Third Affiliated Hospital of Guangzhou Medical...

Recruiting

Dynamic Monitoring of ctDNA and HPV DNA in Plasma for the Early Prediction of Recurrence After Cervical Cancer Surgery

cfHPV DNA in Plasma of Cervical Cancer Patients

China
Peter MacCallum Cancer Centre, Australia
AbbVie

Not yet recruiting

MRD-Directed Consolidation With Epcor-only or Epcor-R2 Post Anti-CD19 CAR TCell Therapy for Large B-Cell Lymphoma (EpLCART)

Relapsed/Refractory Large B-cell Lymphoma

Australia
Exact Sciences Corporation
NSABP Foundation Inc

Not yet recruiting

EXActDNA-003 / NSABP B-64: Study of Molecular Residual Disease Detection in Breast Cancer (MRD)

Breast Cancer
Exact Sciences Corporation
Labcorp Corporation of America Holdings, Inc

Recruiting

First CORRECT Study of Minimal Residual Disease (MRD) Detection in Colorectal Cancer (MRD)

Colorectal Cancer

United Kingdom, Spain, Italy, Israel
Elisabethinen Hospital
Medical University Innsbruck

Recruiting

Liquid Biopsy (ctDNA) Guided Treatment in Localized Pancreatic Cancer: Neoadjuvant CTX vs. Upfront Surgery (LIQUIPANC)

Pancreatic Cancer | Circulating Tumor Cell | Predictive Cancer Model

Austria
Shanghai Zhongshan Hospital

Not yet recruiting

Biomarkers and Molecular Mechanism Study of Hepatocellular Carcinoma After Radical Resection and Conversion Therapy

Hepatocellular Carcinoma

China
University of Rome G. Marconi
University of Bologna; University of the Italian Switzerland

Not yet recruiting

Poor Sleep During Pregnancy as Risk Factor for Post-partum Stress and Mental Health (MOTHERS)

Stress | Insomnia | Postpartum Depression

Italy
University Hospital, Basel, Switzerland
Research Center for Clinical Neuroimmunology and Neuroscience Basel

Not yet recruiting

Implementation of Liquid Biopsies During Routine Clinical Care in Patients With Advanced Malignancies (LIQPLAT) (LIQPLAT)

Advanced Solid Tumor
Obstetrics & Gynecology Hospital of Fudan University
Peking Union Medical College Hospital; First Affiliated Hospital of Xinjiang... and other collaborators

Not yet recruiting

Role of Methylation Test Triage in HPV Positive Women (MTTRIHPW)

Precancerous Cervical Lesion

China
Sixth Affiliated Hospital, Sun Yat-sen University

Recruiting

Dynamic Multi-omics Integration Model to Predict Neoadjuvant Therapy Response in Locally Advanced Rectal Cancer

Predictive Cancer Model | Pathologic Complete Response

China

Search clinical trials for: ctDNA Methylation Haplotypes

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