Search clinical trials for: fractional dose

Total 21465 results

Cairo University

Not yet recruiting

Fractional Carbon Dioxide Laser: A Novel Therapeutic Option for Lichen Simplex Chronicus

Lichen Simplex Chronicus

Egypt
Leiden University Medical Center

Recruiting

Coadministration of GA2 Sporozoites With Adjuvants (CoGA)

Malaria,Falciparum

Netherlands
Boston University
National Institute of Mental Health (NIMH); Massachusetts General Hospital; New... and other collaborators

Active, not recruiting

Supporting Sustained HIV Treatment Adherence After Initiation (SUSTAIN)

HIV Infections | Adherence, Medication

South Africa
Murdoch Childrens Research Institute
Indonesia University; Universitas Padjadjaran; Health Development Policy Agency... and other collaborators

Withdrawn

Evaluation of COVID-19 Vaccines Given as a Booster in Healthy Adults in Indonesia (MIACoV Indonesia)

COVID-19

Indonesia
GlaxoSmithKline

Completed

An Ancillary Study Protocol to GSK's Phase IIb Malaria Vaccine Trial Entitled "Efficacy, Safety and Immunogenicity Study of GSK Biologicals' Candidate Malaria Vaccine (SB257049) Evaluating Schedules With or Without Fractional Doses, Early Dose 4 and Yearly Doses, in Children 5-17 Months of Age"

Malaria

Ghana, Kenya
University of Oxford
KEMRI-Wellcome Trust Collaborative Research Program; Institut Pasteur; MRC/UVRI... and other collaborators

Completed

Non- Inferiority Fractional-doses Trial for Yellow Fever Vaccine (NIFTY)

Yellow Fever

Kenya, Uganda
Albert B. Sabin Vaccine Institute
Stanford University; Aga Khan University; Oswaldo Cruz Foundation

Completed

Immunogenicity and Safety of Fractional Booster Dose of COVID-19 Vaccines Available for Use in Pakistan/Brazil: A Phase 4 Dose-optimizing Trial

COVID-19

Brazil, Pakistan
Istanbul Training and Research Hospital

Completed

Effects of Subanesthetic Dose of Ketamine Given on Postoperative Mood in Patients Undergoing Fractional Curettage

Ketamine | Woman | Minor Surgical Procedure | Total Mood Score

Turkey
University of Vermont
World Health Organization

Active, not recruiting

Intradermal Fractional Dose IPV (fIPV) in Combination With dmLT

Poliomyelitis

United States
London School of Hygiene and Tropical Medicine
University College, London; Bill and Melinda Gates Foundation; Wellcome Trust; KEMRI-Wellcome... and other collaborators

Active, not recruiting

The Effect of Fractional Doses of Pneumococcal Conjugate Vaccines on Immunogenicity and Carriage in Kenyan Infants (FPCV)

Pneumococcal Infection | Streptococcus Pneumoniae Infection | Invasive Pneumococcal Disease, Protection Against

Kenya
GlaxoSmithKline

Completed

Efficacy, Safety and Immunogenicity Study of GSK Biologicals' Candidate Malaria Vaccine (SB257049) Evaluating Schedules With or Without Fractional Doses, Early Dose 4 and Yearly Doses, in Children 5-17 Months of Age

Malaria

Ghana, Kenya
Epicentre
Kenya Medical Research Institute; LSHTM; Universite Abdou Moumouni de Niamey UAM

Active, not recruiting

Mass Campaigns With Fractional Dose Pneumococcal Vaccines in Sub-Saharan Africa (fPCV) (fPCV)

Pneumococcal Carriage

Niger
Fidec Corporation
Bill and Melinda Gates Foundation

Completed

A Study to Evaluate Immunogenicity of Intramuscular Full-Dose and Intradermal Fractional Dose of IPV

Poliomyelitis

Dominican Republic, Panama
University of Washington

Active, not recruiting

Intradermal, Fractional Dose of HPV Vaccines:

HPV Infection | HPV Vaccine

United States
University of Washington

Active, not recruiting

Immunogenicity of Fractional Dose of the HPV Vaccines

HPV Infection | HPV Vaccine

United States
Murdoch Childrens Research Institute
Coalition for Epidemic Preparedness Innovations; The Peter Doherty Institute...

Completed

Evaluation of Full Versus Fractional Doses of COVID-19 Vaccines Given as a Booster in Adults in Australia - Mongolia, Indonesia, Australia Coronavirus (MIACoV). (MIACoV)

COVID-19

Australia
Murdoch Childrens Research Institute
Coalition for Epidemic Preparedness Innovations; The Peter Doherty Institute...

Active, not recruiting

Evaluation of Full Versus Fractional Dose of COVID-19 Vaccine Given as a Booster for the Prevention of COVID-19 in Adults in Mongolia.

COVID-19

Mongolia
Centers for Disease Control and Prevention
International Centre for Diarrhoeal Disease Research, Bangladesh; World Health... and other collaborators

Enrolling by invitation

Assessing Immunogenicity of Intramuscular Sabin Inactivated Poliovirus Vaccine and Non-inferiority of Intradermal Fractional Inactivated Poliovirus Vaccine

Poliomyelitis

Bangladesh
PATH
GlaxoSmithKline; Kenya Medical Research Institute; US Army Medical Research Directorate-Africa... and other collaborators

Completed

RTS,S/AS01E Hypo-immuno-responsiveness Study

Plasmodium Falciparum

Kenya
Central Clinical Hospital of the Russian Academy...
Ural State Medical University; De Haar Research Task Force; De Haar Research... and other collaborators

Terminated

Natural History of Coronary Atherosclerosis in Real-World Stable Chest Pain Patients Underwent Computed Tomography Angiography in Comparison With Invasive Multimodality Imaging (REALITY)

Coronary Artery Disease | Alzheimer Disease | Contrast-induced Nephropathy | Coronary Atherosclerosis | Cerebrovascular Disease | Stable Chronic Angina | Chronic Coronary Insufficiency

Netherlands, Russian Federation, Estonia
University of Oxford

Completed

Malaria Vaccine Safety and Immunogenicity Study in Healthy Adults (RTSS)

Malaria Vaccine

Thailand
Epicentre
Kenya Medical Research Institute

Completed

Immunogenicity and Safety of Fractional Doses of Yellow Fever Vaccines (YEFE) (YEFE)

Yellow Fever

Uganda, Kenya
Assistance Publique - Hôpitaux de Paris

Completed

Open Randomized Trial Evaluating Four Anti-pneumococcal Vaccine Strategies With Fractionated Doses of Non Conjugate Polysaccharide Vaccine to Prevent Hyporesponse in Healthy Volunteers (HYPOPNEUMO)

Pneumococcal Infection
GlaxoSmithKline
PATH

Completed

A Study to Evaluate the Efficacy, Immunogenicity and Safety in a Sporozoite Challenge Model of a Fractional Booster Dose of GSK Biologicals' Candidate Malaria Vaccine Administered to Previously Vaccinated Healthy Malaria-naïve Adults

Malaria

United States
Aga Khan University
World Health Organization

Unknown

Use of mOPV1 in Routine Immunization in Pakistan. (mOPV1)

Oral Polio Vaccine

Pakistan
University of Vermont

Completed

Evaluation of Safety, Reactogenicity and Immunogenicity of Fractional-dose Inactivated Polio Vaccine (fIPV) Given Intradermally With Double Mutant Enterotoxigenic Escherichia Coli Heat Labile Toxin (dmLT) Adjuvant

Polio

United States
University of Dundee

Completed

Dose Response of Fractional Exhaled Nitric Oxide (FeNO) to Inhaled Steroids in Mild-to-moderate Asthma

Asthma

United Kingdom
Aga Khan University
World Health Organization

Unknown

Comparison of Immunity Following IPV Versus fIPV: a Community Based Randomized Controlled Trial in Pakistan (CODI)

Poliomyelitis | Immunization; Infection | Poliovirus Vaccine, Inactivated

Pakistan
Centers for Disease Control and Prevention
MRC/UVRI and LSHTM Uganda Research Unit; Ministry of Health, Uganda; Infectious...

Unknown

Immunogenicity of Fractional One-fifth and One-half Doses of Yellow Fever Vaccine Compared to Full Dose in Children 9-23 Months Old

Yellow Fever
Aga Khan University
World Health Organization

Completed

ID Administration of fIPV Using Intradermal Adapters vs. BCG Syringe (ID-ADAP)

IPV
University of Patras

Completed

Differential Effect of High (200μg/kg/Min) Adenosine Dose on Fractional Flow Reserve in Patients Presenting Variation of FFR ≥0.05 During the Usual Dose of Adenosine Infusion (140μg/kg/Min).

Coronary Artery Disease

Greece
Gilead Sciences
Nimbus Apollo

Completed

Study to Evaluate the Pharmacodynamic Effects of a Single Oral Dose of GS-0976 (NDI-010976) in Healthy Adult Subjects

PD Effects of GS-0976 (NDI-010976) on Fractional DNL

United States
Sanofi Pasteur, a Sanofi Company

Completed

Immunogenicity and Safety of Fractional Doses of IPV Intradermally vs Full Doses Intramuscularly

Poliomyelitis

Philippines
Sanofi Pasteur, a Sanofi Company

Completed

Immunogenicity and Safety of a Fractional Booster Dose of IPV Intradermally Versus Full Dose Intramuscularly

Poliomyelitis

Philippines
Odense University Hospital

Completed

Influence of Intensive Lipid Lowering Treatment Compared to Moderate Lipid Lowering Treatment

Myocardial Infarction [C14.907.585.500]

Denmark
University of Sao Paulo General Hospital

Unknown

Serological Evaluation of Varicella and Hepatitis A Vaccines Using Injector Delivery (InjHepAVar)

Hepatitis A | Varicella

Brazil
Epicentre
University of Oslo; Norwegian Institute of Public Health; Medecins Sans Frontieres...

Completed

Fractional Dose Tetravalent A, C, Y, W135 Meningococcal Polysaccharide Vaccine

Infections, Meningococcal | Meningitis, Meningococcic

Norway, Uganda
Celgene

Not yet recruiting

A Study to Evaluate the Safety, Tolerability, and Drug Levels of Orally Administered BMS-986368 in Healthy Participants, Healthy Elderly Participants, and Healthy Participants of Japanese Ethnicity

Healthy Participants

United States
Tongji Hospital

Not yet recruiting

Oliceridine-Enhanced Analgesia and Recovery: A G-Protein Biased μ-Opioid Study

Postoperative Analgesia
Bill & Melinda Gates Medical Research Institute

Not yet recruiting

Study To Evaluate Safety, Tolerability, and Pharmacokinetics of MAM01 in African Population

Healthy Volunteers

Kenya, Uganda
Boehringer Ingelheim

Not yet recruiting

A Study in Healthy People to Compare How 2 Different Low Dose Formulations of BI 1015550 Are Taken up in the Body

Healthy
Sanofi

Recruiting

A Study to Evaluate the Treatment Response and Safety of Two Dose Regimens of Subcutaneous Amlitelimab Monotherapy Compared With Treatment Withdrawal in Participants Aged 12 Years and Older With Moderate-to-severe Atopic Dermatitis (ESTUARY)

Dermatitis Atopic

United States
Wuxi People's Hospital

Recruiting

Low-dose Chemotherapy Under Hypoglycaemia for the Treatment of Relapsed Refractory Advanced Solid Tumours

Solid Tumors, Adult

China
Wave Life Sciences Ltd.

Not yet recruiting

A Phase 1b/2a, Open-label Single Ascending Doses and Multiple Ascending Doses Study in Participants With Pi*ZZ AATD (RestorAATion-2)

Alpha-1 Antitrypsin Deficiency
Bayer

Not yet recruiting

A Study to Learn About How BAY 3283142 Moves Into, Through, and Out of the Body After a Single Dose in Participants With Reduced Liver Function Compared to Participants With Normal Liver Function

Chronic Kidney Disease | Hepatic Impairment
Traws Pharma, Inc.

Recruiting

Evaluation Safety, Tolerability, and Pharmacokinetics of Single and Multiple Ascending Doses of 83-0060 in Healthy Volunteers

Healthy Volunteers Only

Australia
Semmelweis University

Recruiting

The Effect of an Additional Pre-extubational Loading Dose of Caffeine-citrate (NEOKOFF22)

Premature Birth | Respiratory Failure | Apnea of Prematurity

Hungary
Assiut University

Not yet recruiting

Topical Simvastatin Versus Topical Steroid in Treatment of Alopecia Areata

Alopecia Areata

Egypt
Eilean Therapeutics

Recruiting

Study of Single and Multiple Ascending Doses of ZE46-0134 in Healthy Volunteers

AML

Australia
University Hospital, Ghent
Belgium Health Care Knowledge Centre

Not yet recruiting

Proactive TDM Versus Standard Use of Biologics in Psoriasis (HELIOS)

Psoriasis Vulgaris

Belgium

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