Search clinical trials for: hepatotoxicity of isoniazid

Total 428737 results

University of California, San Francisco
Boston University; Boston Medical Center; Mbarara University of Science and Technology

Completed

Alcohol Drinkers' Exposure to Preventive Therapy for TB (ADEPTT) (ADEPTT)

HIV/AIDS | Tuberculosis | Alcohol Abuse

Uganda
National Taiwan University Hospital

Unknown

NAT2 Genotyping in Re-challenge Protocol of INH Titration in Patients With Anti-TB Medications-induced Hepatitis

Hepatotoxicity

Taiwan
National Taiwan University Hospital
Department of Health, Executive Yuan, R.O.C. (Taiwan)

Unknown

NAT2 in Re-challenge of INH in Patients With Hepatitis

Tuberculosis | Hepatotoxicity

Taiwan
All India Institute of Medical Sciences, New Delhi

Completed

Anti-tuberculosis (TB) Drug Levels and Correlation With Drug Induced Hepatotoxicity

Hepatitis | Tuberculosis

India
All India Institute of Medical Sciences, New Delhi

Completed

Study of Safety and Efficacy of Different Regimes of Reintroduction of Anti-TB Drugs in Anti-TB Drugs Induced Liver Damage

Tuberculosis | Drug Induced Hepatotoxicity

India
University of Cologne

Terminated

Isoniazid Dose Adjustment According to NAT2 Genotype (IDANAT2)

Pulmonary Tuberculosis

Germany, Bulgaria, Poland
All India Institute of Medical Sciences, New Delhi

Completed

Anti-tuberculosis (TB) Drug Levels and Hepatotoxicity

Hepatitis | Tuberculosis

India
Beijing Chest Hospital
The First Affiliated Hospital with Nanjing Medical University; Anhui Chest... and other collaborators

Recruiting

Efficacy Safety BaiDiZiYin ShenQiYiFei Adjunctive Treatments Pulmonary Tuberculosis

Tuberculosis | Treatment | Adjuvant

China
Brigham and Women's Hospital
University of Cape Town; APIN Public Health Initiatives

Not yet recruiting

Dolutegravir Pharmacokinetics During Weekly Rifapentine/Isoniazid for TB Prevention

Latent Tuberculosis | Pediatric HIV Infection
Johns Hopkins University
United States Agency for International Development (USAID)

Not yet recruiting

Shortened Regimen for Drug-susceptible TB in Children (SMILE-TB)

Tuberculosis | Tuberculosis, Pulmonary | Mycobacterium Tuberculosis | Tuberculosis, Lymph Node

Uganda, South Africa, Mozambique, Indonesia, Zambia
Fundación Pública Andaluza para la Investigación...

Not yet recruiting

Proof-of-concept to Evaluate the Efficacy and Safety of Prednisone in Idiosyncratic Hepatotoxicity (DILICORT)

Prednisone | Hepatotoxicity | Idiosyncratic Drug Effect
University of Washington
National Institute of Allergy and Infectious Diseases (NIAID); Human Sciences...

Recruiting

ThiPhiSA: New Pathways to Prevention From Community TB Screening in South Africa (ThiPhiSA)

Tuberculosis

South Africa
Freundeskreis Für Internationale Tuberkulosehilfe...

Not yet recruiting

1HP Versus 3HR in the Treatment of Tuberculosis Infection in Vietnam

Tuberculosis Infection

Vietnam
National Institute of Allergy and Infectious Diseases...
TB Alliance

Not yet recruiting

Trial of Novel Regimens for the Treatment of Pulmonary Tuberculosis (RAD-TB)

Pulmonary Tuberculosis

Botswana, Brazil, Haiti, India, Kenya, Malawi, Mexico, Peru, Philippines, South Africa, Thailand, Uganda, Zimbabwe
University College, London
London School of Hygiene and Tropical Medicine; Radboud University Medical... and other collaborators

Recruiting

Platform Assessing Regimens and Durations In a Global Multisite Consortium for TB (PARADIGM4TB)

Pulmonary Tuberculosis

South Africa
Centre Hospitalier Universitaire, Amiens

Recruiting

Relevance of Isoniazid Dosage in Adults Treated for Tuberculosis (ISOBK)

Tuberculosis

France
Huashan Hospital

Recruiting

TB YOUTH - TB sYstemic Management Using One-month, Ultra-short TPT Regimen for scHool Contacts (TB-YOUTH)

Latent Tuberculosis | Tuberculosis

China
Queen Mary University of London
University of Washington; University of Oxford; KEMRI-Wellcome Trust Collaborative... and other collaborators

Not yet recruiting

An Adaptive Multi-arm Trial to Improve Clinical Outcomes Among Children Recovering From Complicated SAM (Co-SAM)

HIV | Severe Acute Malnutrition | Comorbidities and Coexisting Conditions | Child Malnutrition
Bill & Melinda Gates Medical Research Institute
Global Alliance for TB Drug Development; Janssen Pharmaceutica; Otsuka Pharmaceutical...

Recruiting

Efficacy and Safety Evaluation of Two to Four Months of Treatment With the Combination Regimens of DBOS and PBOS in Adults With Pulmonary Tuberculosis

Pulmonary Tuberculosis

South Africa, Philippines
Indian Council of Medical Research
Christian Medical College, Vellore, India; Jawaharlal Institute of Postgraduate... and other collaborators

Not yet recruiting

Intensified Short Course Regimen for TBM in Adults (INSHORT)

Tuberculous Meningitis

India
Michael Hoelscher
Radboud University Medical Center; University College, London; University of...

Recruiting

PanACEA - STEP2C -01

Pulmonary Tuberculosis | Other Specified Pulmonary Tuberculosis

Gabon, South Africa, Tanzania, Malawi, Uganda, Mozambique
Centers for Disease Control and Prevention
Tuberculosis Trials Consortium

Recruiting

Short-course Regimens for the Treatment of Pulmonary Tuberculosis (CRUSH-TB)

Tuberculosis, Pulmonary | Tuberculosis Infection

Canada, United States, Haiti, South Africa, Uganda, Vietnam
Brigham and Women's Hospital
University of California, Los Angeles; University of Stellenbosch; University... and other collaborators

Recruiting

Ultra-Short Course Bedaquiline, Clofazimine, Pyrazinamide and Delamanid Versus Standard Therapy for Drug-Susceptible TB (PRESCIENT)

HIV | Tuberculosis, Pulmonary

South Africa, Haiti
Children's Hospital of Orange County
University of California, Irvine

Recruiting

Use of Levocarnitine to Reduce Asparaginase Hepatotoxicity in Patients With Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia | Hepatotoxicity

United States
TASK Applied Science

Recruiting

A Phase 2 Trial to Evaluate the EBA, Safety and Tolerability of Eto Alone and in Combination With BVL-GSK098 (BETO)

Rifampicin- and Isoniazid-Susceptible Pulmonary Tuberculosis (TB)

South Africa
First Affiliated Hospital of Zhejiang University

Not yet recruiting

Sitafloxacin-containing Regimens for Shortening Tuberculosis Treatment

Tuberculosis, Pulmonary
University of Zurich

Recruiting

Safety and Tolerability of Chlorquine in Addition to Anti-tuberculosis Therapy

Tuberculosis Infection

Switzerland
Central South University

Recruiting

Hepatotoxicity Related to Protein Kinase Inhibitors

Cancer

China
Stanford University
National Institute of Allergy and Infectious Diseases (NIAID); Federal University... and other collaborators

Recruiting

Point-of-care Pharmacogenomic Testing to Optimize Isoniazid Dosing for Tuberculosis Prevention

Tuberculosis Infection | Isoniazid Adverse Reaction

Brazil
Rutgers, The State University of New Jersey

Recruiting

One-month Latent Tuberculosis Treatment for Renal Transplant Candidates

End Stage Renal Disease | Latent Tuberculosis | Renal Transplant Candidate for Right Kidney | Renal Transplant Candidate for Left Kidney

United States
National Institute of Allergy and Infectious Diseases...

Recruiting

Trial of a Six-Month Regimen of High-Dose Rifampicin, High-Dose Isoniazid, Linezolid, and Pyrazinamide Versus a Standard Nine-Month Regimen for the Treatment of Adults and Adolescents With Tuberculous Meningitis

Tuberculous Meningitis

South Africa, Zimbabwe, India, Kenya, Malawi, Mexico, Peru, Brazil, Philippines, Tanzania, Thailand, Vietnam
West China Hospital

Not yet recruiting

The Prophylaxis of Tuberculosis According to TSPOT Results After Kidney Transplantation (PTTKT)

Tuberculosis | Kidney Transplant Infection | Isoniazid Toxicity
Makerere University

Recruiting

Pharmacogenetics-guided Isoniazid Dosing in TB-HIV (PHINX)

Tuberculosis

Uganda
The Aurum Institute NPC
Johns Hopkins University

Recruiting

Rifapentine and Isoniazid TB Preventive Therapy (3HP) for Children Taking Dolutegravir-based Antiretroviral Treatment (DOLPHIN KIDS) (DOLPHIN KIDS)

HIV | Tuberculosis

South Africa
The Aurum Institute NPC
Johns Hopkins University; Weill Medical College of Cornell University; University...

Recruiting

Safety and Tolerability of 1 Month Daily (1HP) and 3 Months Weekly (3HP) Isoniazid and Rifapentine With Pharmacokinetics of Dolutegravir (DTG) in Pregnant People With HIV (DOLPHIN Moms)

Pregnancy | HIV Seropositivity | Tuberculosis Infection

South Africa
The Aurum Institute NPC
Johns Hopkins University

Recruiting

Comparing Treatment Completion Of Daily Rifapentine & Isoniazid For One Month (1HP) To Weekly High Dose Rifapentine & Isoniazid For 3 Months (3HP) In Persons Living With HIV and in Household Contacts of Recently Diagnosed Tuberculosis Patients (1 to 3)

Tuberculosis | HIV Seropositivity | Household Contact

South Africa, India, Indonesia, Mozambique
Region Skane

Recruiting

Rifampicin Resistance in S. Aureus During and After Treatment for Latent Tuberculosis

Staphylococcus Aureus | Latent Tuberculosis

Sweden
Miguel Santín
Institut d'Investigació Biomèdica de Bellvitge; Instituto de Salud Carlos III

Not yet recruiting

Short-course Rifamycin-based Regimens for Latent Tuberculosis in Patients With End-stage Kidney Disease

Latent Tuberculosis | Kidney Failure
Institut National de la Santé Et de la Recherche...
National Agency for Research on AIDS and Viral Hepatitis (ANRS)

Not yet recruiting

Impact of Malnutrition on Pharmacokinetic or Rifampicin, Isoniazid, Pyrazinamide and Ethambutol in TB-HIV Co-infected Children (TB-Speed TB-PK)

Tuberculosis | Pulmonary

Uganda, Zambia
University of Cape Town

Recruiting

Testing New Strategies for Patients Hospitalised With HIV-associated Disseminated Tuberculosis (NEW-STRAT TB)

HIV | Disseminated Tuberculosis

South Africa
University of Massachusetts, Worcester
National Institute of Allergy and Infectious Diseases (NIAID); Aurum Institute and other collaborators

Recruiting

Safety and Tolerability of Metformin in People With Tuberculosis (TB) and Human Immunodeficiency Virus (HIV) (METHOD)

Tuberculosis | Pulmonary Tuberculosis | HIV Coinfection

South Africa
ANRS, Emerging Infectious Diseases
European and Developing Countries Clinical Trials Partnership (EDCTP); European...

Recruiting

Determination of Adequate Tuberculosis Regimen in Patients Hospitalized With HIV-associated Severe Immune Suppression (DATURA)

Tuberculosis | HIV-1-infection | Immuno-Deficiency

Uganda, Cambodia, Cameroon, Guinea, Vietnam, Zambia
Daiichi Sankyo, Inc.

Recruiting

A Long-term Study Evaluating Hepatotoxicity Associated With TURALIO™ (Pexidartinib) Treatment

Tenosynovial Giant Cell Tumor | Hepatotoxicity

United States
Dr. Nyanda Elias Ntinginya
King's College London; Makerere University; Stichting Katholieke Universiteit-... and other collaborators

Recruiting

Preventive Treatment Of Latent Tuberculosis Infection In People With Diabetes Mellitus (PROTID)

Diabetes Mellitus | Tuberculosis

Uganda, Tanzania
Aswan University Hospital

Recruiting

Vaginal Dinoprostone Versus Isonicotinic Acid Hydrazide Prior to Diagnostic Office Hysteroscopy

Postmenopausal Bleeding

Egypt
Seoul National University Hospital
Pusan National University Hospital; Chonnam National University Hospital; Seoul... and other collaborators

Not yet recruiting

Treatment Shortening of Drug-Sensitive Pulmonary Tuberculosis Using High Dose Rifampicin (Hi-DoRi-3) (Hi-DoRi-3)

Tuberculosis, Pulmonary

Korea, Republic of
University of Nottingham
Pfizer

Recruiting

Checkpoint Inhibitor-induced Liver Injury (ChILI)

Immune-Mediated Hepatitis

United Kingdom
Fifth Affiliated Hospital, Sun Yat-Sen University

Not yet recruiting

Efficacy and Safety of Isoniazid, Rifampicin and Moxifloxacin for the Intensive Phase of Initial Therapy of PTB

Pulmonary Tuberculosis

China
University of Florida
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Recruiting

Adequacy of the New Pediatric Isoniazid/Rifampin/Pyrazinamide (HRZ) Tablet

Tuberculosis | Human Immunodeficiency Virus | Coinfection

Ghana
Hospices Civils de Lyon

Recruiting

Pharmacokinetics Variability of Posaconazole (PCZ) and Its Glucuronide Metabolite During Induction and Consolidation Treatments in Patients With Acute Myeloid Leukemia (AML): a Covariate Analysis With the Tablets Formulation and Evaluation of the Potential Risk of Hepatotoxicity (Posa-Pk)

Leukemia, Myeloid, Acute

France

Search clinical trials for: hepatotoxicity of isoniazid

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