Search clinical trials for: lacosamide

Total 106 results

Kafrelsheikh University

Recruiting

Lacosamide Versus Topiramate in Migraine

Migraine Disorders

Egypt
University of North Carolina, Chapel Hill

Recruiting

Antiseizure Medication in Seizure Networks at Early Acute Brain Injury

Stroke | Brain Ischemia | Brain Injuries, Traumatic | Heart Arrest | Intracranial Hemorrhages | Brain Hypoxia | Coma | Hypoxia-Ischemia, Brain | Persistent Vegetative State | Brain Injuries, Acute

United States
Xiangya Hospital of Central South University

Recruiting

Improvement Effect of Lacosamide and Levetiracetam on Cognitive in Alzheimer's Disease Patients With Epilepsy

Epilepsy | Alzheimer Disease 3

China
Overseas Pharmaceuticals, Ltd.
Beijing Capton Pharmaceutical Technology Development Co., LTD

Not yet recruiting

An Open Label, Balanced, Randomized, Two-Treatment, Two-Period, Two-Sequence, Two-way Crossover, Oralcomparative Pharmacokinetic（PK）Study of Lacosamide Extended-Release Tablets , Adult, Human Subjects Under Fasting Conditions.

Epilepsy

China
University of Milano Bicocca
Azienda Ospedaliera Universitaria Integrata Verona; Azienda Socio Sanitaria... and other collaborators

Recruiting

Dual Anti-glutamate Therapy in Super-refractory Status Epilepticus After Cardiac Arrest (SUPER-CAT)

Cardiac Arrest | Status Epilepticus

Italy
Tanta University

Recruiting

Effect of Silymarin in Metastatic Colorectal Cancer Patients

Metastatic Colorectal Cancer

Egypt
Indiana University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

STTEPP: Safety, Tolerability and Dose Limiting Toxicity of Lacosamide in Patients With Painful Chronic Pancreatitis (STTEPP)

Chronic Pain | Opioid-Related Disorders | Opioid Use Disorder | Opioid Dependence | Chronic Pancreatitis | Hyperalgesia | Chronic Pain Syndrome | ERCP | Pancreatic Surgery | Chronic Abdominal Pain

United States
Tanta University

Recruiting

Comparative Clinical Study Evaluating the Possible Efficacy of Duloxetine, Gabapentin and Lacosamide on Oxaliplatin-Induced Peripheral Neuropathy in Cancer Patients

Oncology

Egypt
Sherief Abd-Elsalam

Recruiting

Lacosamide in Neonatal Status Epilepticus

Epilepsy

Egypt
UCB Biopharma SRL

Recruiting

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Lacosamide in Neonates With Repeated Electroencephalographic Neonatal Seizures (LENS)

Epilepsy | Electroencephalographic Neonatal Seizures

United States, Australia, Canada
Laniado Hospital

Not yet recruiting

Addition of Dydrogesterone to the Luteal Phase Support After Fresh Embryo Transfer

Infertility | IVF

Israel
Assistance Publique - Hôpitaux de Paris

Recruiting

Population Pharmacokinetics of Antiepileptic in Pediatrics (EPIPOP)

Epilepsy

France
UCB Pharma

Completed

A Trial to Investigate the Safety, Tolerability and Pharmacokinetics of Intravenous SPM 927

Epilepsy
UCB Pharma

Completed

A Multi-Centre, Randomized, Double-Blind, Placebo Controlled Pilot Trial to Assess the Efficacy, Safety, and Tolerability of SPM 927 in Subjects With Postherpetic Neuralgia (PHN).

Postherpetic Neuralgia
The Hospital for Sick Children
St. Justine's Hospital; University of Waterloo

Completed

Drug Concentrations in Breast Milk and Prediction of Blood Levels of the Breastfed Infants

Breast Feeding

Canada
UCB Pharma
SCHWARZ BIOSCIENCES GmbH - Part of UCB Group

Completed

A Trial to Assess the Efficacy and Safety of 400mg/Day Lacosamide in Subjects With Painful Diabetic Neuropathy

Painful Diabetic Neuropathy

Germany
Kafrelsheikh University

Completed

The Lacosamide's Effect on Calcitonin Gene-related Peptide in Migraine Patients

Migraine Disorders | Effect of Drug

Egypt
Leiden University Medical Center

Completed

Combined Effect of Pregabalin and Oxycodone, and Lacosamide and Oxycodone, on Breathing (POLO)

Opioid-induced Respiratory Depression

Netherlands
UCB Pharma

Completed

An Open-label follow-on Trial to Assess the Long-term Safety and Efficacy of Oral SPM 927 in Subjects With Diabetic Neuropathy

Painful Diabetic Neuropathy
UCB BIOSCIENCES, Inc.

Completed

Safety and Efficacy of Lacosamide as Additional Therapy in Patients Suffering From Epileptic Tonic-Clonic Seizures (VALUE)

Epilepsy

United States, Australia, Brazil, Bulgaria, China, Czechia, France, Germany, Hungary, Israel, Italy, Japan, Korea, Republic of, Mexico, Poland, Portugal, Romania, Russian Federation, Slovakia, Spain, Taiwan
Kafrelsheikh University

Completed

Lacosamide Versus Propranolol in Migraine

Migraine Disorders

Egypt
UCB Biopharma SRL

Active, not recruiting

A Study to Test the Long-term Use of Oral Lacosamide in Pediatric Study Participants Who Completed NCT01964560 (EP0034) or NCT00938912 (SP848) and Received Lacosamide Treatment

Epilepsy

Georgia, Hungary, Moldova, Republic of, Romania, Taiwan, Ukraine
UCB Pharma

Completed

Study Evaluating Long-term Safety and Efficacy of Lacosamide in Subjects With Painful Distal Diabetic Neuropathy.

Painful Diabetic Neuropathy

Russian Federation, Austria, Belgium, Bulgaria, Czechia, Finland, France, Germany, Hungary, Italy, Poland, Romania, Serbia, Spain, United Kingdom
UCB Pharma
SCHWARZ BIOSCIENCES GmbH - Part of UCB Group

Completed

A Trial to Assess the Long-term Safety and Efficacy of Lacosamide in Subjects With Painful Diabetic Neuropathy

Painful Diabetic Neuropathy

Germany
Liu Yonghong
First Affiliated Hospital Xi'an Jiaotong University; Second Affiliated Hospital... and other collaborators

Enrolling by invitation

Acute Sympotomatic Seizure Secondary to Autoimmune Encephalitis and Autoimmune-associated Epilepsy

Epilepsy | Seizures | Autoimmune Encephalitis

China
UCB Biopharma S.P.R.L.
Parexel

Completed

A Clinical Study to Investigate the Long-term Use of Lacosamide as Monotherapy in Subjects Who Completed Study SP0994

Epilepsy

Bulgaria, Finland, France, Germany, Japan, Korea, Republic of, Latvia, Mexico, Philippines, Poland, Romania, Russian Federation, Sweden, Switzerland, Ukraine
Duke University

Terminated

Seizure Prophylaxis in Patients With Glioma or Brain Metastasis

Glioma | Brain Tumor | Glioma of Brain

United States
UCB BIOSCIENCES, Inc.

Completed

Study to Investigate Safety and Tolerability of Intravenous Lacosamide in Children. (ASPIRE)

Epilepsy

United States, Hungary, Italy, Poland, Ukraine
Danish Pain Research Center
Odense University Hospital

Terminated

The Effect of Lacosamide in Peripheral Neuropathic Pain

Neuropathic Pain | Neuropathy | Neuropathy, Diabetic | Neuropathy;Peripheral | Neuropathy, Painful

Denmark
Pakistan Institute of Medical Sciences
Riphah International University

Completed

COMPARISON OF EFFICACY OF DIFFERENT DRUG COMBINATIONS IN ACUTE SCIATICA (EDCLAS)

Sciatica | Sciatica Acute

Pakistan
UCB BIOSCIENCES, Inc.
UCB Biopharma SRL

Completed

A Clinical Study to Investigate the Efficacy and Safety of Lacosamide as an Add on Therapy in Children With Epilepsy With Partial-onset Seizures

Epilepsy

United States, Argentina, Australia, Belgium, Brazil, Bulgaria, China, Colombia, Croatia, Czechia, Estonia, France, Georgia, Greece, Hungary, Israel, Italy, Korea, Republic of, Latvia, Lithuania, Mexico, Moldova, Republic of, Monten... and more
University of California, San Francisco
San Francisco VA Health Care System

Completed

Pilot Human Lab Study of Lacosamide in Alcohol Use Disorder (AUD) (ACGT)

Alcohol Use Disorder

United States
UCB BIOSCIENCES, Inc.

Completed

An Open-Label Study to Determine Safety , Tolerability, and Efficacy of Oral Lacosamide in Children With Epilepsy

Epilepsy

United States, Belgium, China, France, Germany, Hungary, Italy, Japan, Mexico, Poland, Ukraine
University of Maryland, Baltimore

Completed

Pharmacokinetics of Antiepileptics in Patients on CRRT (PADRE)

Renal Insufficiency | Renal Failure | Acute Kidney Injury | Pharmacokinetics

United States
UCB Pharma SA
UCB Japan Co. Ltd.

Completed

Study to Evaluate the Safety, Tolerability, and Efficacy of Long-term Adjunctive Therapy With Lacosamide in Adults With Partial-onset Seizures

Epilepsy | Partial-onset Seizures

China, Japan
UCB BIOSCIENCES, Inc.

Completed

Efficacy and Safety of Lacosamide as Adjunctive Therapy in Subjects ≥1 Month to <4 Years With Partial-onset Seizures

Epilepsy With Partial-onset Seizures

United States, Argentina, Brazil, Bulgaria, China, Croatia, Czechia, France, Georgia, Greece, Hungary, Israel, Italy, Korea, Republic of, Mexico, Moldova, Republic of, Philippines, Poland, Portugal, Romania, Russian Federation, Se... and more
Boston Medical Center
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Completed

Lacosamide Effects on Alcohol Self Administration and Craving in Heavy Drinkers

Alcohol Use Disorder

United States
Jiangxi Qingfeng Pharmaceutical Co. Ltd.

Unknown

A Real World Study on the Efficacy and Safety of Lacosamide as Add-on Therapy for Focal-onset Epilepsy

Epilepsy | Focal-Onset Seizure

China
UCB BIOSCIENCES GmbH
Eden Sarl

Completed

Trial Comparing the Efficacy and Safety of Lacosamide (LCM) to Carbamazepine Controlled-Release (CBZ-CR); Initial Monotherapy in Epilepsy; Subjects Aged 16 and Older (SP0993)

Epilepsy | Monotherapy

United States, Australia, Belgium, Bulgaria, Canada, Czechia, Finland, France, Germany, Greece, Hungary, Italy, Japan, Korea, Republic of, Latvia, Lithuania, Mexico, Philippines, Poland, Portugal, Romania, Russian Federation, Slovakia, Spa... and more
UCB BIOSCIENCES, Inc.
Pharmaceutical Research Associates

Completed

A Study to Assess the Safety and Efficacy of Lacosamide Versus Placebo (a Pill Without Active Medication) in Patients With Idiopathic Generalised Epilepsy Who Are Already Taking Anti-epileptic Medications (VALOR)

Epilepsy

United States, Australia, Belgium, Brazil, Bulgaria, China, Czechia, France, Germany, Hungary, Israel, Italy, Japan, Korea, Republic of, Mexico, Poland, Portugal, Romania, Russian Federation, Slovakia, Spain, Taiwan
Le Bonheur Children's Hospital

Completed

IV Lacosamide: The Safety of Intravenous Lacosamide

Epilepsy

United States
Le Bonheur Children's Hospital

Completed

The Safety of Intravenous Lacosamide

Epilepsy

United States
Chiba University

Completed

Open-label Clinical Trial of Lacosamide in ALS

Amyotrophic Lateral Sclerosis

Japan
UCB BIOSCIENCES GmbH
PRA Health Sciences

Completed

Study of Lacosamide as an Adjunctive Drug Treatment for Epilepsy in Patients With Brain Tumors (VIBES)

Brain Tumor Related Epilepsy (BTRE)

Italy, France, Germany, Netherlands, Spain, United Kingdom
Second Affiliated Hospital, School of Medicine,...
University of California, Los Angeles; Tongji Hospital; Michigan State University and other collaborators

Unknown

Evaluation of the Efficacy and Safety of Lacosamide in Pediatric Patients With Epilepsy

Epilepsy

China
Seoul National University Hospital
Dongsan Medical Center; Konkuk University

Completed

Efficacy and Safety of Rapid Titration Protocols of Lacosamide

Focal Epilepsy

Korea, Republic of
UCB Biopharma S.P.R.L.

No longer available

Compassionate Use Program With Lacosamide in Patients With Partial-onset or Generalized Tonic-clonic Seizures

Epilepsies, Partial
UCB Japan Co. Ltd.

Completed

A Trial to Evaluate the Long Term Safety and Tolerability of Lacosamide Taken as Monotherapy in Adults With Partial-onset Seizures

Epilepsy | Partial-onset Seizures

Japan
UCB Pharma

Completed

A Study to Investigate the Safety and Efficacy of Lacosamide Added to the Patients Current Therapy in Patients Aged 1 Month to Less Than 18 Years Old With Epilepsy Syndromes Associated With Generalized Seizures.

Epilepsy

United States, France, Hungary, Mexico, Poland
UCB Pharma

Completed

A Multicenter, Open-Label Study To Investigate The Safety And Pharmacokinetics Of Lacosamide In Children With Partial Seizures

Epilepsy

United States, Belgium, Mexico

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