Search clinical trials for: lesotho

Total 43 results

University Hospital, Basel, Switzerland
SolidarMed Lesotho

Recruiting

Measuring Anticipated Attitudes and Behavior Towards a New Medical Treatment in Lesotho

Recruitment | Health Behavior | Motivation | Social Behavior | Health Care Utilization | Consumer Behavior | Health Care Seeking Behavior | Researcher-Subject Relations

Lesotho
FHI 360
United States Agency for International Development (USAID); Jhpiego; Wits Reproductive... and other collaborators

Recruiting

The CATALYST Study

HIV Prevention

Kenya, Lesotho, South Africa, Uganda, Zimbabwe
University Hospital, Basel, Switzerland
SolidarMed

Recruiting

Substituting SMSs for Provider-delivered Care to Improve Alcohol Use Outcomes

Alcohol Use Disorder, Mild | Alcohol Use Disorder, Moderate

Lesotho
Harvard Medical School (HMS and HSDM)
National Institute of Allergy and Infectious Diseases (NIAID); Partners in... and other collaborators

Recruiting

Strengthening Evidence on Optimal Multidrug-resistant Tuberculosis Treatment Regimens (STEM-TB)

HIV | Tuberculosis, Multidrug-Resistant

Kazakhstan, Lesotho, Peru
University Hospital, Basel, Switzerland
SolidarMed; Swiss Agency for Development and Cooperation (SDC); World Diabetes...

Recruiting

Community-based, eHealth Supported Type 2 Diabetes Care by Lay Village Health Workers in Rural Lesotho (ComBaCaL T2D)

Type 2 Diabetes Mellitus (T2D)

Lesotho, Switzerland
University Hospital, Basel, Switzerland
Swiss Agency for Development and Cooperation (SDC); World Diabetes Foundation...

Recruiting

"Community-based, eHealth Supported Management of Cardiovascular Risk Factors by Lay Village Health Workers (ComBaCaL aHT TwiC 1 & ComBaCaL aHT TwiC 2)

Arterial Hypertension

Lesotho, Switzerland
University Hospital, Basel, Switzerland
SolidarMed; Swiss Agency for Development and Cooperation (SDC); World Diabetes...

Recruiting

Community-Based Chronic Disease Care in Rural Lesotho (ComBaCaL)

Non-communicable Diseases (NCDs)

Lesotho, Switzerland
Klaus Reither
Radboud University Medical Center; Charite University, Berlin, Germany; Institute... and other collaborators

Recruiting

Tuberculosis Diagnostic Trial of CAD4TB Screening Alone Compared to CAD4TB Screening Combined With a CRP Triage Test, Both Followed by Confirmatory Xpert MTB/RIF Ultra in Communities of Lesotho and South Africa

Tuberculosis

Lesotho, South Africa
University of Cape Town
Institute of Tropical Medicine, Belgium; Epicentre; Medecins Sans Frontieres,... and other collaborators

Recruiting

Pharmacometrics to Advance Novel Regimens for Drug-resistant Tuberculosis-PandrTB Tuberculosis (PandrTB)

Multi-drug Resistant Tuberculosis

Vietnam, Kazakhstan, Lesotho, Pakistan, Peru, South Africa
University Hospital, Basel, Switzerland
London School of Hygiene and Tropical Medicine; Swiss National Science Foundation and other collaborators

Active, not recruiting

Same-day Versus Rapid ART Initiation in HIV-positive Individuals Presenting With Symptoms of Tuberculosis (SaDAPT)

Human Immunodeficiency Virus (HIV) Infection

Lesotho, Malawi
University of California, Santa Barbara
Ministry of Health, Lesotho; Fulbright

Completed

A Brief Affirmation Intervention on HIV-related Distress and Positive Living in Lesotho

Counseling | Self-affirmation Plus Positive Living Counseling
Swiss Tropical & Public Health Institute
University of Zurich; University Hospital, Basel, Switzerland; University of... and other collaborators

Active, not recruiting

Tolerability of Lopinavir Versus Dolutegravir for Children and Adolescents Living With HIV (LoDoCA)

HIV

Lesotho
Columbia University
Centers for Disease Control and Prevention; Ministry of Health, Lesotho; National...

Completed

PROvide MIner-friendly SErvices for Integrated TB/HIV Care in Lesotho Study (PROMISE)

HIV

Lesotho
Boston University
Fogarty International Center of the National Institute of Health

Completed

Nthabi in Lesotho - Implementation

Preconception Care

Lesotho
Médecins Sans Frontières, France
Harvard Medical School (HMS and HSDM); Institute of Tropical Medicine, Belgium and other collaborators

Completed

Evaluating Newly Approved Drugs for Multidrug-resistant TB (endTB)

Tuberculosis, Multidrug-Resistant | Infection, Bacterial | Pulmonary Tuberculoses

Pakistan, Georgia, India, Kazakhstan, Lesotho, Peru, South Africa
Swiss Tropical & Public Health Institute
University Hospital, Basel, Switzerland; University of Basel; Ifakara Health... and other collaborators

Completed

Genotype-Informed Versus Empiric Management of VirEmia (GIVE MOVE)

HIV-1-infection

Lesotho, Tanzania
Médecins Sans Frontières, France
Harvard Medical School (HMS and HSDM); Institute of Tropical Medicine, Belgium and other collaborators

Active, not recruiting

Evaluating Newly Approved Drugs in Combination Regimens for Multidrug-Resistant TB With Fluoroquinolone Resistance (endTB-Q) (endTB-Q)

Bacterial Infections | Gram-Positive Bacterial Infections | Tuberculosis | Tuberculosis, Multidrug-Resistant | Pulmonary Tuberculoses | Mycobacterial Infections

Vietnam, Pakistan, India, Kazakhstan, Lesotho, Peru
Swiss Tropical & Public Health Institute
University of Basel; Ministry of Health, Lesotho; District Health Management... and other collaborators

Completed

Dolutegravir in Real Life in Lesotho (DO-REAL)

HIV-1-infection

Lesotho
Swiss Tropical & Public Health Institute

Active, not recruiting

Viral Load Triggered ART Care in Lesotho (VITAL)

HIV Infections

Lesotho
Elizabeth Glaser Pediatric AIDS Foundation

Completed

TB Innovation Project: A Pre- and Post- Implementation Assessment (TIPPI) (TIPPI)

Tuberculosis | Pediatric

Cameroon, Congo, The Democratic Republic of the, Côte D'Ivoire, India, Kenya, Lesotho, Malawi, Tanzania, Uganda, Zimbabwe
Elizabeth Glaser Pediatric AIDS Foundation
Janssen, LP

Active, not recruiting

Characteristics and Outcomes of Patients Who Received Etravirine and/or Darunavir (NewHorizon)

HIV/AIDS

Cameroon, Kenya, Lesotho, Swaziland, Uganda
University Hospital, Basel, Switzerland
Swiss National Fund for Scientific Research

Completed

Identifying Most Effective Treatment Strategies to Control Arterial Hypertension in Sub-Saharan Africa (coArtHA)

Arterial Hypertension

Lesotho, Switzerland, Tanzania
Klaus Reither
Radboud University Medical Center; Charite University, Berlin, Germany; University... and other collaborators

Completed

Diagnostic Accuracy of CAD4TB and C-reactive Protein Assay as Triage Tests for Pulmonary Tuberculosis (TB TRIAGE+)

Covid-19 | HIV | Pulmonary Tuberculosis | Tuberculosis Diagnosis

Lesotho, South Africa
Partners in Health
Harvard Medical School (HMS and HSDM); Epicentre; Interactive Research and Development and other collaborators

Completed

Expand New Drugs for TB [endTB]

Tuberculosis, Multidrug-Resistant

Georgia, Armenia, Bangladesh, Belarus, Ethiopia, Indonesia, Kazakhstan, Kenya, Kyrgyzstan, Lesotho, Myanmar, Pakistan, Peru, South Africa
Columbia University
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Preventing Childhood Tuberculosis in Lesotho (PREVENT Study)

Tuberculosis

Lesotho
Niklaus Labhardt
University Hospital, Basel, Switzerland; Swiss Tropical & Public Health Institute and other collaborators

Completed

"Switch Either Near Suppression Or THOusand" (SESOTHO)

HIV/AIDS

Lesotho
Columbia University
United States Agency for International Development (USAID)

Completed

Start TB Patients on ART and Retain on Treatment (START Study) (START)

HIV | Tuberculosis

Lesotho
Amstutz Alain
Swiss National Science Foundation; University Hospital, Basel, Switzerland; Swiss... and other collaborators

Completed

Peer-Educator-coordinated vs Nurse-coordinated ART Refill for Adolescents and Young Adults Living With HIV in Lesotho (PEBRA)

HIV/AIDS

Lesotho
Niklaus Labhardt
University Hospital, Basel, Switzerland; University of Basel; Ministry of Health... and other collaborators

Completed

Village-based vs Clinic-based ART Care - a Cluster Randomized Controlled Trial in Lesotho (VIBRA)

HIV/AIDS

Lesotho
University of California, Los Angeles
Boston University; United States Agency for International Development (USAID); Ministry of Health, Zambia and other collaborators

Terminated

INTERVAL: Varying Intervals of ART to Improve Outcomes in HIV (INTERVAL)

HIV-1-infection

Malawi, Zambia
Elizabeth Glaser Pediatric AIDS Foundation
Johns Hopkins University; United States Agency for International Development... and other collaborators

Completed

A Multidisciplinary "Integrated Management Team to Improve Maternal-Child Outcomes (IMPROVE)" Intervention to Improve Maternal and Child Outcomes in Lesotho (IMPROVE)

Human Immunodeficiency Virus
GlaxoSmithKline

Completed

A Study to Evaluate the Effect of Itraconazole on the Pharmacokinetics (PK) of Nemiralisib

Pulmonary Disease, Chronic Obstructive

United States
Swiss Tropical & Public Health Institute
University of Basel; Ministry of Health, Lesotho; SolidarMed

Completed

Short Adherence Intervention for Viral Re-suppression (SAVIR)

HIV/AIDS | Adherence, Medication

Lesotho
Tracy Glass
University Hospital, Basel, Switzerland; University of Basel; Ministry of Health... and other collaborators

Completed

HOme-based SElf-testiNG - a Cluster Randomized Controlled Trial in Rural Lesotho (HOSENG) (HOSENG)

HIV/AIDS | HIV

Lesotho
Swiss Tropical & Public Health Institute
University of Basel; University of Geneva, Switzerland; SolidarMed - Swiss Organization... and other collaborators

Completed

Same-day ART Initiation Versus Standard of Care After Positive HIV-test Result in Rural Lesotho (CASCADE)

HIV Infection

Lesotho
Equip, Lesotho
United States Agency for International Development (USAID); Elizabeth Glaser... and other collaborators

Unknown

Outcomes of Differentiated Models of Antiretroviral Treatment (ART) Provision ([MMD])

HIV/AIDS

Lesotho
Swiss Tropical & Public Health Institute
University of Basel; SolidarMed - Swiss Organization for Health in Africa; Swiss... and other collaborators

Completed

Comorbidities and Virologic Outcome Among Patients on Anti-retroviral Therapy in Rural Lesotho

Depression | Alcoholism | Hepatitis | Metabolic Syndrome | HIV

Lesotho
University of Toronto

Completed

Reducing Lesbian, Gay , Bisexual and Transgender (LGBT) Stigma in Swaziland and Lesotho

Social Stigma

Lesotho, Swaziland
Columbia University

Completed

Enhanced HIV Prevention in Couples: Feasibility Study #1 (EPIC)

Human Immunodeficiency Virus (HIV) | Acquired Immune Deficiency Syndrome (AIDS)

Lesotho
Columbia University
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Enhanced Prevention in Couples: Feasibility Study #2 (EPIC)

Human Immunodeficiency Virus (HIV) | Acquired Immune Deficiency Syndrome (AIDS)

Lesotho
Columbia University
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Enhanced HIV Prevention in Couples: Feasibility Study #3 (EPIC)

Human Immunodeficiency Virus (HIV) | Acquired Immune Deficiency Syndrome (AIDS)

Lesotho
Bocconi University
World Bank

Unknown

The Impact of Short-term Financial Incentives on Sexual Behavior and HIV Incidence in Lesotho

Sexually Transmitted Diseases | AIDS/HIV PROBLEM

United Kingdom
SolidarMed
Paray Mission Hospital, Thaba-Tseka; Seboche Hospital, Botha-Bothe

Completed

Comparison of Door-to-door Versus Community Gathering to Provide HIV Counseling and Testing Services in Rural Lesotho (DoDoPi)

Diabetes Mellitus | HIV/AIDS | Tuberculosis | Arterial Hypertension

Lesotho

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