Search clinical trials for: new synthetic opioids

Total 69651 results

University of Zurich
University Children's Hospital, Zurich

Recruiting

Observational Study on the Incorporation of Opioids and Their Metabolites Into Hair of Pediatric Patients

Opioid Use, Unspecified

Switzerland
Chulalongkorn University

Not yet recruiting

"Quick-starting" of a New Combined Hormonal Contraceptive Pills, 15 mg Estetrol/3 mg Drospirenone VS 20 mcg Ethinylestradiol/75 mcg Gestodene Focusing on Ovulation Inhibition

Ultrasound Finding: Ovulation Inhibition, Ovarian Activities | Cervical Mucus | Serum Hormonal Profile
University of Kent
Kent Community Health NHS Foundation Trust; NHS Kent and Medway

Recruiting

DE-eSCALation of Opioids Post-surgical dischargE (DESCALE)

Opioid Dependence

United Kingdom
AbbVie

Recruiting

A Study to Assess the Safety and Efficacy of Oral Armour Thyroid Compared to Synthetic T4 for the Treatment of Primary Hypothyroidism in Adult Participants

Hypothyroidism

United States
Yale University
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Not yet recruiting

Oral Contraceptive Pill (OCP) Pharmacogenomics

Contraception | Pharmacogenomic Drug Interaction

United States
Servier Bio-Innovation LLC
Institut de Recherches Internationales Servier

Recruiting

S095035 in Adult Participants With Advanced or Metastatic Solid Tumors With Deletion of the Methylthioadenosine Phosphorylase (MTAP) Gene

MTAP-deleted Solid Tumors

Australia, United States
Soligenix

Recruiting

HyBryte (Synthetic Hypericin) Versus Valchlor (Mechlorethamine) in the Treatment of CTCL

Cutaneous T-Cell Lymphoma/Mycosis Fungoides

United States
Memorial Sloan Kettering Cancer Center
Astellas Pharma US, Inc.; Corcept Therapeutics; Breast Cancer Research Foundation

Recruiting

A Study of Enzalutamide, Enzalutamide in Combination With Mifepristone, or Chemotherapy in People With Metastatic Breast Cancer

Metastatic Breast Cancer

United States
Rutgers, The State University of New Jersey

Recruiting

Search to Advance Limited Use of Opioids Pilot: Optimization of Non-Opioid Therapy With a Steroid (SAILS-Steroid)

Pain Management

United States
State University of New York at Buffalo
University of Pennsylvania; Thomas Jefferson University

Recruiting

Cannabis Use and Outcomes in Black and White Patients With Cancer (C4C)

Cancer

United States
Wake Forest University Health Sciences

Not yet recruiting

Randomized Controlled Trial (RCT) Umbilical Hernia Repair (UHR) Absorbable vs Non-absorbable Synthetic Mesh

Umbilical Hernia

United States
Washington University School of Medicine
National Cancer Institute (NCI)

Not yet recruiting

A Behavioral Intervention to Promote Primary Prevention and Uterine Preservation in Premenopausal Women With Obesity and Endometrial Hyperplasia

Endometrial Hyperplasia | Grade 1 Endometrial Cancer

United States
NYU Langone Health
National Institute of General Medical Sciences (NIGMS)

Not yet recruiting

Harm Reduction Services (HRS)

Mental Illness | Substance Abuse | Drug Use

United States
Corcept Therapeutics

Recruiting

Study to Determine the Prevalence of Hypercortisolism in Patients With Type 2 Diabetes and Treatment With Korlym® (Mifepristone) (CATALYST)

Diabetes Mellitus, Type 2 | Hypercortisolism

United States
Mackay Medical College

Recruiting

Efficacy/Safety of Urogynecology Synthetic Mesh Surgery

Pelvic Organ Prolapse | Stage III and IV High Grade Pelvic Organ Prolapse

Taiwan
National Cancer Institute (NCI)
NRG Oncology

Recruiting

Testing the Addition of the AKT Inhibitor, Ipatasertib, to Treatment With the Hormonal Agent Megestrol Acetate for Recurrent or Metastatic Endometrial Cancers

Recurrent Endometrial Endometrioid Adenocarcinoma | Stage IV Uterine Corpus Cancer AJCC v8 | FIGO Grade 1 Endometrial Endometrioid Adenocarcinoma | FIGO Grade 2 Endometrial Endometrioid Adenocarcinoma | Metastatic Endometrial Endometrioid Adenocarcinoma

United States
Go Medical Industries Pty Ltd
National Institute on Drug Abuse (NIDA); Columbia University; University at Buffalo and other collaborators

Not yet recruiting

Evaluation of the O'Neil Long Acting Naltrexone Implant in Opioid Dependent Persons (GM0020)

Opioid Use Disorder
Rutgers, The State University of New Jersey

Recruiting

Reducing Pain From Wisdom Molar Extractions

Acute Pain

United States
OssDsign

Recruiting

OssDsign® Spine Registry Study ("Propel")

Degenerative Disc Disease | Spinal Stenosis

United States
Far Eastern Memorial Hospital

Recruiting

HRT on Overactive Bladder Symptoms, Sexual Function, Depressive Symptoms, Autonomic Function, and Arterial Stiffness

Menopausal Syndrome

Taiwan
Mirati Therapeutics Inc.

Recruiting

Phase 1/2 Study of MRTX1719 in Solid Tumors With MTAP Deletion

Pancreatic Adenocarcinoma | Solid Tumor | Non Small Cell Lung Cancer | Mesothelioma | Advanced Solid Tumor | Malignant Peripheral Nerve Sheath Tumors

United States
NewGiza University
Ain Shams University

Not yet recruiting

The Association of Hormonal Intake and Demographic Factors With Breast Cancer Risk. An Egyptian Case-controlled Study

Observational Study
Mahmoud Ramadan mohamed Elkazzaz
Ministry of Health, Saudi Arabia

Not yet recruiting

Investigating the Potential Role of a Novel Quadrate Combination Therapy Mifepristone(Antiprogestrone), Tamoxifen, Retinoic Acid and Cannabidiol ( Selective Cyp 26 Inhibitor) for Treating Early Breast Cancer.

Breast Cancer Female
Prof. Janet Dunn
King's College Hospital NHS Trust; University of Manchester; University of Birmingham and other collaborators

Recruiting

Repurposed Drugs to Improve Haematological Responses in Myelodysplastic Syndromes (REPAIR-MDS)

Myelodysplastic Syndromes (MDS)

United Kingdom
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Recruiting

Olanzapine Versus Megestrol Acetate for the Treatment of Loss of Appetite Among Advanced Cancer Patients

Hematopoietic and Lymphoid Cell Neoplasm | Anorexia | Advanced Malignant Solid Neoplasm

United States
Linepharma International LTD

Recruiting

Effectiveness and Safety of Combination Mifepristone/Misoprostol for Medical Abortion (MiMAC)

Medical Abortion

Canada
Rutgers, The State University of New Jersey
New Jersey Health Foundation

Not yet recruiting

Twin Block, Pain Medications and Third Molar Extractions

Acute Pain

United States
IDEAYA Biosciences

Recruiting

Study of IDE397 in Participants With Solid Tumors Harboring MTAP Deletion

Solid Tumor

United States, Taiwan, Korea, Republic of, France, Spain, Australia, Germany
University of Alabama at Birmingham
Patient-Centered Outcomes Research Institute

Recruiting

RA-PRO PRAGMATIC TRIAL (RA-PROPR)

Rheumatoid Arthritis

United States, Canada
University of New Mexico
National Institute on Drug Abuse (NIDA); Johns Hopkins University; Duke University and other collaborators

Recruiting

Pain and Opioids: Integrated Treatment In Veterans (POSITIVE)

Chronic Pain | Opioid-use Disorder | Opioids; Harmful Use

United States
Syracuse University
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Recruiting

Personalized Feedback Intervention for Alcohol and Opioid Use Among Adults With Chronic Pain

Alcohol Drinking | Pain | Opioid Use | Feedback, Psychological

United States
Albany Medical College

Recruiting

No Opioids PrescrIptions On Discharge After Surgery (NOPIOiDS)

Postoperative Pain | Surgery | Opioid Use | Prescription Drug Abuse and Dependency

United States
University of Oxford
Bill and Melinda Gates Foundation; Department for International Development... and other collaborators

Recruiting

Randomised Evaluation of COVID-19 Therapy (RECOVERY)

Severe Acute Respiratory Syndrome

Ghana, Indonesia, Nepal, South Africa, United Kingdom, Vietnam, India
University of Saskatchewan

Recruiting

Effect of Multimodal Opioid-free Anesthesia on Return of Bowel Function in Laparoscopic Colorectal Surgery (RUMBLE)

Laparoscopic Surgery | Analgesia | Colorectal Surgery | Anesthesia | Ketamine | General Anesthesia | Dexmedetomidine | Postoperative Ileus | Analgesics, Opioid | Lidocaine | Opioid Free Anesthesia

Canada
Health Decisions
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Recruiting

A Study to Evaluate the PK and PD of IM or SQ Injections of Levonorgestrel Butanoate (LB) for Female Contraception

Female Contraception | Healthy Women

United States
National Development and Research Institutes, Inc.
New York University; Rhode Island Hospital; Drexel University; Brandeis University

Recruiting

Overdose Risk Management and Naloxone

Opioid Use

United States
Kirby Institute
National Health and Medical Research Council, Australia

Recruiting

ETHOS ENGAGE: Enhancing Treatment of Hepatitis C in Opioid Substitution Settings (ETHOS II)

Hepatitis C

Australia
National Cancer Institute (NCI)

Recruiting

Testing the Addition of an Individualized Vaccine to Nab-Paclitaxel, Durvalumab and Tremelimumab and Chemotherapy in Patients With Metastatic Triple Negative Breast Cancer

Anatomic Stage IV Breast Cancer AJCC v8 | Invasive Breast Carcinoma | Metastatic Triple-Negative Breast Carcinoma

United States
Tetra Bio-Pharma
Cognitive Research Corporation

Recruiting

Inhaled Cannabinoids Versus Immediate-release Oral Opioids for the Management of Breakthrough Cancer Pain (REBORN)

Cancer | Breakthrough Cancer Pain

United States
AbbVie

Recruiting

A Study to Assess the Effect of Venetoclax on Ethinyl Estradiol and Levonorgestrel in Female Participants With Different Hematological Malignancies

Hematologic Malignancies

United States, Australia
Medicines360

Completed

Study of a Levonorgestrel 52 mg Intrauterine System for the Treatment of Heavy Menstrual Bleeding

Menorrhagia

United States
VA Office of Research and Development

Active, not recruiting

Treatment, Pain, and Opioids

Chronic Pain

United States
Myovant Sciences GmbH

Completed

LIBERTY EXTENSION: Efficacy and Safety Extension Study of Relugolix in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids

Uterine Fibroid | Heavy Menstrual Bleeding

United States, Italy, Belgium, Czechia, Hungary, Poland, South Africa, Chile, Brazil
Brown University
National Institute on Drug Abuse (NIDA); New York University

Active, not recruiting

Preventing Overdose Using Information and Data From the Environment (PROVIDENT)

Drug Overdose | Opioid Overdose

United States
National Institute of Diabetes and Digestive and...
Massachusetts General Hospital; University of Pennsylvania; Yale University; New... and other collaborators

Active, not recruiting

HOPE Consortium Trial to Reduce Pain and Opioid Use in Hemodialysis (HOPE)

Chronic Pain | End Stage Renal Disease | Opioid Dependence

United States
Daniel Grossman, MD

Completed

Mail Order Mifepristone Study

Pregnancy Related | Abortion Early

United States
SetPoint Medical Corporation

Active, not recruiting

Vagus Nerve Stimulation for Moderate to Severe Rheumatoid Arthritis (RESET-RA)

Rheumatoid Arthritis

United States
Go Medical Industries Pty Ltd
National Institute on Drug Abuse (NIDA); Columbia University; New York State... and other collaborators

Completed

Pharmacokinetic Study of Vivitrol in Healthy Participants

Opioid-use Disorder

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Levonorgestrel-Releasing Intrauterine System With or Without Everolimus in Treating Patients With Atypical Hyperplasia or Stage IA Grade 1 Endometrial Cancer (LEVER)

Atypical Endometrial Hyperplasia | FIGO Grade 1 Endometrial Endometrioid Adenocarcinoma | FIGO Grade 2 Endometrial Endometrioid Adenocarcinoma

United States
Indiana University
LCMC Health; The Society for Pediatric Anesthesia

Completed

Investigating Interventions to Reduce Residual Opioids in the Home Following Legitimate Opioid Prescribing in Children.

Opioid Use, Unspecified

United States

Search clinical trials for: new synthetic opioids

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